Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Nagaki, T Naiki, D A Brenner, Y Osawa, M Imose, H Hayashi, Y Banno, S Nakashima, H Moriwak. Tumor necrosis factor alpha prevents tumor necrosis factor receptor-mediated mouse hepatocyte apoptosis, but not fas-mediated apoptosis: role of nuclear factor-kappaB. Hepatology (Baltimore, Md.). vol 32. issue 6. 2001-01-04. PMID:11093734. |
tumor necrosis factor alpha (tnf-alpha) binding to the tnf receptor (tnfr) initiates apoptosis and simultaneously activates the transcription factor, nuclear factor-kappab (nf-kappab), which suppresses apoptosis by an unknown mechanism. |
2001-01-04 |
2023-08-12 |
mouse |
F Su, C N Theodosis, R J Schneide. Role of NF-kappaB and myc proteins in apoptosis induced by hepatitis B virus HBx protein. Journal of virology. vol 75. issue 1. 2001-01-04. PMID:11119591. |
hbx stimulates cytoplasmic signal transduction pathways, moderately stimulates a number of transcription factors, including several nuclear factors, and in certain settings sensitizes cells to apoptosis by proapoptotic stimuli, including tumor necrosis factor alpha (tnf-alpha) and etopocide. |
2001-01-04 |
2023-08-12 |
Not clear |
E Tonner, G J Allan, D J Flin. Hormonal control of plasmin and tissue-type plasminogen activator activity in rat milk during involution of the mammary gland. The Journal of endocrinology. vol 167. issue 2. 2000-12-15. PMID:11054640. |
since alpha(s2)-casein also binds plasminogen and tissue-type plasminogen activator (t-pa), resulting in the conversion of plasminogen to plasmin, and since igfbp-5 binds to plasminogen activator inhibitor-1 (pai-1), we investigated whether apoptosis and extracellular matrix (ecm) degradation might be coordinately controlled by gh and prl possibly acting through igfbp-5. |
2000-12-15 |
2023-08-12 |
rat |
T Kita, T Tanaka, N Tanaka, Y Kinoshit. The role of tumor necrosis factor-alpha in diffuse axonal injury following fluid-percussive brain injury in rats. International journal of legal medicine. vol 113. issue 4. 2000-12-07. PMID:10929238. |
it is generally accepted that tnf alpha directly induces primary demyelination and oligodendrocyte apoptosis. |
2000-12-07 |
2023-08-12 |
rat |
N Kyprianou, J Chon, C M Bennin. Effects of alpha(1)-adrenoceptor (alpha(1)-AR) antagonists on cell proliferation and apoptosis in the prostate: therapeutic implications in prostatic disease. The Prostate. Supplement. vol 9. 2000-11-30. PMID:11056502. |
effects of alpha(1)-adrenoceptor (alpha(1)-ar) antagonists on cell proliferation and apoptosis in the prostate: therapeutic implications in prostatic disease. |
2000-11-30 |
2023-08-12 |
Not clear |
N Kyprianou, J Chon, C M Bennin. Effects of alpha(1)-adrenoceptor (alpha(1)-AR) antagonists on cell proliferation and apoptosis in the prostate: therapeutic implications in prostatic disease. The Prostate. Supplement. vol 9. 2000-11-30. PMID:11056502. |
this work examined the effects of selected alpha(1)-adrenoceptor (alpha(1)-ar) antagonists (blockers) on cellular dynamics to determine whether induction of apoptosis or inhibition of proliferation could contribute to the overall clinical profile. |
2000-11-30 |
2023-08-12 |
Not clear |
V Müller-Wieprecht, C Riebeling, A Stooss, C E Orfanos, C C Geile. Bcl-2 transfected HaCaT keratinocytes resist apoptotic signals of ceramides, tumor necrosis factor alpha and 1 alpha, 25-dihydroxyvitamin D(3). Archives of dermatological research. vol 292. issue 9. 2000-11-28. PMID:11000289. |
the results obtained showed that apoptosis induced by c(2)-ceramide, tumor necrosis factor alpha or 1 alpha,25-dihydroxyvitamin d(3) occurred in a vector-transfected clone but not in a bcl-2-transfected hacat clone. |
2000-11-28 |
2023-08-12 |
human |
W S Colucci, D B Sawyer, K Singh, C Communa. Adrenergic overload and apoptosis in heart failure: implications for therapy. Journal of cardiac failure. vol 6. issue 2 Suppl 1. 2000-11-21. PMID:10908092. |
likewise, mice that overexpress beta1-ar or g alpha s in the myocardium develop left ventricular dilation, contractile dysfunction and apoptosis. |
2000-11-21 |
2023-08-12 |
mouse |
S Perdow-Hickman, P Salgam. Rescue of human T cells by interleukin-9 (IL-9) from IL-2 deprivation-induced apoptosis: correlation with alpha subunit expression of the IL-9 receptor. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 6. 2000-11-17. PMID:10888117. |
rescue of human t cells by interleukin-9 (il-9) from il-2 deprivation-induced apoptosis: correlation with alpha subunit expression of the il-9 receptor. |
2000-11-17 |
2023-08-12 |
human |
S Perdow-Hickman, P Salgam. Rescue of human T cells by interleukin-9 (IL-9) from IL-2 deprivation-induced apoptosis: correlation with alpha subunit expression of the IL-9 receptor. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 20. issue 6. 2000-11-17. PMID:10888117. |
in summary, the data showed that il-9 can rescue only a small subset of th2 cells from apoptosis induced by growth factor withdrawal and that expression of il-9r alpha is required for the antiapoptotic signals mediated by this cytokine. |
2000-11-17 |
2023-08-12 |
human |
L Yan, V Herrmann, J K Hofer, P A Inse. beta-adrenergic receptor/cAMP-mediated signaling and apoptosis of S49 lymphoma cells. American journal of physiology. Cell physiology. vol 279. issue 5. 2000-11-16. PMID:11029315. |
we conclude that betaar activation induces apoptosis in immature t lymphocytes via g(s)alpha and pka, while overexpression of bcl-2 prevents cell death. |
2000-11-16 |
2023-08-12 |
Not clear |
Y Liu, Y Hong, E J Androphy, J J Che. Rb-independent induction of apoptosis by bovine papillomavirus type 1 E7 in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 275. issue 40. 2000-11-13. PMID:10887172. |
rb-independent induction of apoptosis by bovine papillomavirus type 1 e7 in response to tumor necrosis factor alpha. |
2000-11-13 |
2023-08-12 |
human |
Y Liu, Y Hong, E J Androphy, J J Che. Rb-independent induction of apoptosis by bovine papillomavirus type 1 E7 in response to tumor necrosis factor alpha. The Journal of biological chemistry. vol 275. issue 40. 2000-11-13. PMID:10887172. |
our results indicate that expression of bpv-1 e7 sensitizes cells to tumor necrosis factor alpha (tnf)-induced apoptosis. |
2000-11-13 |
2023-08-12 |
human |
C K Lee, R L Weaks, G A Johnson, F W Bazer, J A Piedrahit. Effects of protease inhibitors and antioxidants on In vitro survival of porcine primordial germ cells. Biology of reproduction. vol 63. issue 3. 2000-11-13. PMID:10952936. |
collectively, these results indicate that the addition of alpha(2)-macroglobulin and antioxidants can increase the number of pgcs in vitro by suppressing apoptosis. |
2000-11-13 |
2023-08-12 |
Not clear |
L Molnár, T Berki, A Hussain, P Németh, H Losoncz. [The role of TNF-alpha in myelodysplastic syndrome: immunoserologic and immunohistochemical studies] . Orvosi hetilap. vol 141. issue 33. 2000-11-09. PMID:10979309. |
in conclusion we suppose that increased tnf alpha expression and production by pbmc may be a further indirect evidence of the role of increased apoptosis in low risk mds patients, in the course of progression the cytokine expression and production decreases. |
2000-11-09 |
2023-08-12 |
Not clear |
C U Niesler, B Ursø, J B Prins, K Siddl. IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-alpha-induced apoptosis, in 3T3-L1 preadipocytes. The Journal of endocrinology. vol 167. issue 1. 2000-11-09. PMID:11018764. |
we have previously shown that human preadipocytes in primary culture undergo apoptosis in response to serum deprivation and addition of tumour necrosis factor alpha (tnf-alpha), and have proposed that regulation of preadipocyte apoptosis in vivo may contribute to the overall control of adipose mass. |
2000-11-09 |
2023-08-12 |
human |
S Chatterjee, A Matsumura, J Schradermeier, G Y Gillespi. Human malignant glioma therapy using anti-alpha(v)beta3 integrin agents. Journal of neuro-oncology. vol 46. issue 2. 2000-11-07. PMID:10894366. |
these results indicated (i) that crgdfv induced apoptosis of human glioma cells by binding alpha(v)beta3 integrin expressed on their cell surfaces and (ii) that crgdfv may be an effective and non-toxic direct anti-tumor therapy for alpha(v)beta3-expressing gbms. |
2000-11-07 |
2023-08-12 |
mouse |
R Matsumura, K Umemiya, T Goto, T Nakazawa, K Ochiai, M Kagami, H Tomioka, E Tanabe, T Sugiyama, M Sueish. Interferon gamma and tumor necrosis factor alpha induce Fas expression and anti-Fas mediated apoptosis in a salivary ductal cell line. Clinical and experimental rheumatology. vol 18. issue 3. 2000-11-07. PMID:10895367. |
interferon gamma and tumor necrosis factor alpha induce fas expression and anti-fas mediated apoptosis in a salivary ductal cell line. |
2000-11-07 |
2023-08-12 |
Not clear |
S Y Huan, C H Yang, Y C Che. Arsenic trioxide therapy for relapsed acute promyelocytic leukemia: an useful salvage therapy. Leukemia & lymphoma. vol 38. issue 3-4. 2000-11-03. PMID:10830735. |
as2o3 can induce partial differentiation and subsequent apoptosis of apl cells through degradation of wild type pml and pml/rar alpha chimeric proteins and possible anti-mitochondrial effects. |
2000-11-03 |
2023-08-12 |
Not clear |
J Y Lee, Y A Hannun, L M Obei. Functional dichotomy of protein kinase C (PKC) in tumor necrosis factor-alpha (TNF-alpha ) signal transduction in L929 cells. Translocation and inactivation of PKC by TNF-alpha. The Journal of biological chemistry. vol 275. issue 38. 2000-11-03. PMID:10887171. |
because of the potential role of protein kinase c (pkc) in apoptosis, we examined the effects and mechanisms of tnf-alpha on pkc regulation, specifically on pkc alpha. |
2000-11-03 |
2023-08-12 |
Not clear |