| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Gnesutta, J Qu, A Minde. The serine/threonine kinase PAK4 prevents caspase activation and protects cells from apoptosis. The Journal of biological chemistry. vol 276. issue 17. 2001-06-14. PMID:11278822. |
expression of wild-type or constitutively active pak4 delays the onset of apoptosis in response to tumor necrosis factor alpha stimulation, uv irradiation, and serum starvation. |
2001-06-14 |
2023-08-12 |
Not clear |
| H Gisslinger, R Kurzrock, B Gisslinger, S Jiang, S Li, I Virgolini, W Woloszczuk, M Andreeff, M Talpa. Autocrine cell suicide in a Burkitt lymphoma cell line (Daudi) induced by interferon alpha: involvement of tumor necrosis factor as ligand for the CD95 receptor. Blood. vol 97. issue 9. 2001-06-14. PMID:11313273. |
it was hypothesized that interferon alpha (ifn-alpha) induces apoptosis through activation of the cd95-mediated pathway and that cd95 and ligands of the death domain may belong to the group of ifn-stimulated genes. |
2001-06-14 |
2023-08-12 |
human |
| D A Potoka, E P Nadler, X Zhou, X R Zhang, J S Upperman, H R For. Inhibition of NF-kappaB by IkappaB prevents cytokine-induced NO production and promotes enterocyte apoptosis in vitro. Shock (Augusta, Ga.). vol 14. issue 3. 2001-06-07. PMID:11028558. |
treatment of adikappab-transfected cells with cytomix [1000 u/ml ifn-gamma, 1 nm il-1beta, and 10 ng/ml tumor necrosis factor alpha (tnfalpha)] or tnfalpha-containing cytokine combinations resulted in inhibition of cytokine-induced nitrite production and a marked increase in apoptosis compared to control cells. |
2001-06-07 |
2023-08-12 |
rat |
| H G Burgert, J H Blusc. Immunomodulatory functions encoded by the E3 transcription unit of adenoviruses. Virus genes. vol 21. issue 1-2. 2001-05-31. PMID:11022786. |
the early transcription unit e3 of ads encodes proteins that inhibit antigen presentation by mhc class i molecules as well as apoptosis induced by tumor necrosis factor alpha (tnf-alpha) and fas ligand (fasl). |
2001-05-31 |
2023-08-12 |
human |
| B Zhang, D Zhang, H Ren, Y M. The effect of Bcl-2 adenovirus against murine hepatocyte apoptosis caused by tumor necrosis factor alpha and D-galactosamine. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 9. issue 1. 2001-05-31. PMID:11242124. |
the effect of bcl-2 adenovirus against murine hepatocyte apoptosis caused by tumor necrosis factor alpha and d-galactosamine. |
2001-05-31 |
2023-08-12 |
Not clear |
| K Suk, I Chang, Y H Kim, S Kim, J Y Kim, H Kim, M S Le. Interferon gamma (IFNgamma ) and tumor necrosis factor alpha synergism in ME-180 cervical cancer cell apoptosis and necrosis. IFNgamma inhibits cytoprotective NF-kappa B through STAT1/IRF-1 pathways. The Journal of biological chemistry. vol 276. issue 16. 2001-05-31. PMID:11278357. |
interferon gamma (ifngamma ) and tumor necrosis factor alpha synergism in me-180 cervical cancer cell apoptosis and necrosis. |
2001-05-31 |
2023-08-12 |
Not clear |
| Y Ashhab, A Alian, A Polliack, A Panet, D Ben Yehud. Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. FEBS letters. vol 495. issue 1-2. 2001-05-21. PMID:11322947. |
the livin alpha but not beta protects cells from apoptosis induced by staurosporine, but in contrast, apoptosis initiated by etoposide was blocked only by the beta isoform. |
2001-05-21 |
2023-08-12 |
human |
| Y Ashhab, A Alian, A Polliack, A Panet, D Ben Yehud. Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern. FEBS letters. vol 495. issue 1-2. 2001-05-21. PMID:11322947. |
these functional and tissue distribution differences of livin alpha and beta suggest that livin may play a complex role in the regulation of apoptosis. |
2001-05-21 |
2023-08-12 |
human |
| K Suk, Y H Kim, I Chang, J Y Kim, Y H Choi, K Y Lee, M S Le. IFNalpha sensitizes ME-180 human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation. FEBS letters. vol 495. issue 1-2. 2001-05-21. PMID:11322949. |
tumor necrosis factor alpha (tnfalpha) induces apoptosis of a variety of tumor cell types. |
2001-05-21 |
2023-08-12 |
human |
| E M Rego, Z G Wang, D Peruzzi, L Z He, C Cordon-Cardo, P P Pandolf. Role of promyelocytic leukemia (PML) protein in tumor suppression. The Journal of experimental medicine. vol 193. issue 4. 2001-05-17. PMID:11181703. |
the promyelocytic leukemia (pml) gene encodes a putative tumor suppressor gene involved in the control of apoptosis, which is fused to the retinoic acid receptor alpha (raralpha) gene in the vast majority of acute promyelocytic leukemia (apl) patients as a consequence of chromosomal translocations. |
2001-05-17 |
2023-08-12 |
mouse |
| K W Kim, H H Chung, C W Chung, I K Kim, M Miura, S Wang, H Zhu, K D Moon, G B Rha, J H Park, D G Jo, H N Woo, Y H Song, B J Kim, J Yuan, Y K Jun. Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: cleavage of the common alpha subunit during apoptosis. Oncogene. vol 20. issue 3. 2001-05-17. PMID:11313965. |
inactivation of farnesyltransferase and geranylgeranyltransferase i by caspase-3: cleavage of the common alpha subunit during apoptosis. |
2001-05-17 |
2023-08-12 |
Not clear |
| C Oberholzer, A Oberholzer, M Clare-Salzler, L L Moldawe. Apoptosis in sepsis: a new target for therapeutic exploration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 6. 2001-05-10. PMID:11292647. |
during sepsis syndromes, lymphocyte apoptosis can be triggered by the absence of il-2 or by the release of glucocorticoids, granzymes, or the so-called 'death' cytokines: tumor necrosis factor alpha or fas ligand. |
2001-05-10 |
2023-08-12 |
Not clear |
| J W Davis, F T Lauer, A D Burdick, L G Hudson, S W Burchie. Prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the MCF-10A cell line: correlation with increased transforming growth factor alpha production. Cancer research. vol 61. issue 8. 2001-05-10. PMID:11309286. |
prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (tcdd) in the mcf-10a cell line: correlation with increased transforming growth factor alpha production. |
2001-05-10 |
2023-08-12 |
human |
| J W Davis, F T Lauer, A D Burdick, L G Hudson, S W Burchie. Prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the MCF-10A cell line: correlation with increased transforming growth factor alpha production. Cancer research. vol 61. issue 8. 2001-05-10. PMID:11309286. |
indeed, in the present studies, the egfr inhibitor ag1478 was able to prevent tcdd-, egf-, and transforming growth factor alpha (tgf-alpha)-dependent cell recovery and inhibition of apoptosis. |
2001-05-10 |
2023-08-12 |
human |
| J Gil, M Esteba. Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action. Apoptosis : an international journal on programmed cell death. vol 5. issue 2. 2001-05-03. PMID:11232238. |
the mechanism of apoptosis induction by pkr involves phosphorylation of eif-2 alpha and activation of nf-kappa b. |
2001-05-03 |
2023-08-12 |
Not clear |
| S Salv. Protecting the myocardium from ischemic injury: a critical role for alpha(1)-adrenoreceptors? Chest. vol 119. issue 4. 2001-05-03. PMID:11296192. |
stimulation of alpha(1)-adrenoreceptors increases glucose transport inside the cardiomyocytes by translocating glucose transporter (glut)-1 and glut-4 from the cytoplasm to the plasma membrane, enhances glycogenolysis by activating phosphorylase kinase, increases the rate of glycolysis by activating the enzyme phosphofructokinase, reduces intracellular acidity produced during excessive glycolysis by activating the na(+)/h(+) exchanger, and inhibits apoptosis by increasing the levels of the antiapoptotic protein bcl-2. |
2001-05-03 |
2023-08-12 |
Not clear |
| N Shah, T J Thomas, J S Lewis, C M Klinge, A Shirahata, C Gelinas, T Thoma. Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells. Oncogene. vol 20. issue 14. 2001-05-03. PMID:11313919. |
in addition, polyamine analogs inhibited the association of er alpha and nf-kappa b with cbp/p300 and were unable to facilitate nuclear translocation of nf-kappa b. apo-brdu assay demonstrated that polyamine analogs induced apoptosis, with a loss of the anti-apoptotic protein bcl-2. |
2001-05-03 |
2023-08-12 |
Not clear |
| M E Reyland, K A Barzen, S M Anderson, D O Quissell, A A Matass. Activation of PKC is sufficient to induce an apoptotic program in salivary gland acinar cells. Cell death and differentiation. vol 7. issue 12. 2001-04-26. PMID:11175257. |
expression of constitutively activated pkc alpha or pkc delta, but not kinase negative mutants of these isoforms, or constitutively activated pkc epsilon, induces apoptosis in salivary acinar cells, suggesting a role for these isoforms in tpa-induced apoptosis. |
2001-04-26 |
2023-08-12 |
Not clear |
| L A Welniak, A R Khaled, M R Anver, K L Komschlies, R H Wiltrout, S Durum, F R Ruscetti, B R Blazar, W J Murph. Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 5. 2001-04-26. PMID:11207240. |
il-7r alpha(-/-) mice and il-7r alpha(+/+) mice were irradiated and examined for lesions and apoptosis within the small intestine. |
2001-04-26 |
2023-08-12 |
mouse |
| L A Welniak, A R Khaled, M R Anver, K L Komschlies, R H Wiltrout, S Durum, F R Ruscetti, B R Blazar, W J Murph. Gastrointestinal cells of IL-7 receptor null mice exhibit increased sensitivity to irradiation. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 5. 2001-04-26. PMID:11207240. |
these results demonstrate the increased radiosensitivity of intestinal stem cells within the crypts in il-7r alpha(-/-) mice and a role for il-7 in the protection of radiation-induced apoptosis in these same cells. |
2001-04-26 |
2023-08-12 |
mouse |