All Relations between apoptosis and alpha

Publication Sentence Publish Date Extraction Date Species
Xin Yang, Heling Zhang, Tong Qu, Yi Wang, Yongxian Zhong, Yuchen Yan, Xuefei Ji, Tiayan Chi, Peng Liu, Libo Zo. Tolfenamic acid inhibits ROS-generating oxidase Nox1-regulated p53 activity in intrastriatal injection of malonic acid rats. The journal of physiological sciences : JPS. vol 72. issue 1. 2022-07-19. PMID:35850611. tolfenamic acid reduced mouse double minute 2 (mdm2), phosphatase and tensin homologue (pten), p53-upregulated modulator of apoptosis (puma) and bcl2-associated x (bax) at the mrna level to inhibit apoptosis and downregulated sestrin 2 (sesn2) and hypoxia inducible factor 1, alpha subunit (hif-1α) mrna levels to exert antioxidative stress effects. 2022-07-19 2023-08-14 mouse
De-Tian Jiang, Lei Tuo, Xiao Bai, Wei-Dong Bing, Qing-Xi Qu, Xin Zhao, Guang-Min Song, Yan-Wen Bi, Wen-Yu Su. Prostaglandin E1 reduces apoptosis and improves the homing of mesenchymal stem cells in pulmonary arterial hypertension by regulating hypoxia-inducible factor 1 alpha. Stem cell research & therapy. vol 13. issue 1. 2022-07-16. PMID:35842683. prostaglandin e1 reduces apoptosis and improves the homing of mesenchymal stem cells in pulmonary arterial hypertension by regulating hypoxia-inducible factor 1 alpha. 2022-07-16 2023-08-14 rat
Yuxuan Zheng, Su Li, Shi-Hua Li, Shaoxiong Yu, Qihui Wang, Kehui Zhang, Liang Qu, Yuan Sun, Yuhai Bi, Fuchou Tang, Hua-Ji Qiu, George F Ga. Transcriptome profiling in swine macrophages infected with African swine fever virus at single-cell resolution. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 19. 2022-07-16. PMID:35507870. mechanistically, the production of tumor necrosis factor alpha (tnf-α) induced by asfv infection is necessary for cell apoptosis, highlighting the importance of tnf-α in asfv pathogenesis. 2022-07-16 2023-08-16 Not clear
Guowu Hu, Pia J Hauk, Nannan Zhang, Waleed Elsegeiny, Carlos M Guardia, Amy Kullas, Kevin Crosby, Robin R Deterding, Michaela Schedel, Paul Reynolds, Jordan K Abbott, Vijaya Knight, Stefania Pittaluga, Mark Raffeld, Sergio D Rosenzweig, Juan S Bonifacino, Gulbu Uzel, Peter R Williamson, Erwin W Gelfan. Autophagy-associated immune dysregulation and hyperplasia in a patient with compound heterozygous mutations in Autophagy. 2022-07-15. PMID:35838483. autophagy-associated immune dysregulation and hyperplasia in a patient with compound heterozygous mutations in bcl2: bcl2 apoptosis regulator; bcl10: bcl10 immune signaling adaptor; card11: caspase recruitment domain family member 11; cbm: card11-bcl10-malt1; cr2: complement c3d receptor 2; ebna: epstein barr nuclear antigen; ebv: epstein-barr virus; fcgr3a; fc gamma receptor iiia; glild: granulomatous-lymphocytic interstitial lung disease; hv: healthy volunteer; ikbkb/ikb kinase: inhibitor of nuclear factor kappa b kinase subunit beta; il2ra: interleukin 2 receptor subunit alpha; malt1: malt1 paracaspase; ms4a1: membrane spanning 4-domain a1; mtor: mechanistic target of rapamycin kinase; myc: myc proto-oncogene, bhlh: transcription factor; ncam1: neural cell adhesion molecule 1; nfkb: nuclear factor kappa b; niaid: national institute of allergy and infectious diseases; nk: natural killer; ptprc: protein tyrosine phosphatase receptor type c; sell: selectin l; pbmcs: peripheral blood mononuclear cells; tr: t cell receptor; tregs: regulatory t cells; wt: wild-type. 2022-07-15 2023-08-14 human
Soyeon Jeong, Ahmed K Farag, Hye Kyeong Yun, Yoon A Jeong, Dae Yeong Kim, Min Jee Jo, Seong Hye Park, Bo Ram Kim, Jung Lim Kim, Bu Gyeom Kim, Dae-Hee Lee, Eun Joo Roh, Sang Cheul O. AF8c, a Multi-Kinase Inhibitor Induces Apoptosis by Activating DR5/Nrf2 via ROS in Colorectal Cancer Cells. Cancers. vol 14. issue 13. 2022-07-09. PMID:35804815. af8c mediated p53-dependent apoptosis of crc cells via the generation of endoplasmic reticulum (er) stress and reactive oxygen species (ros), as well as activation of nuclear respiratory factor 2 alpha subunit (nrf2) and death receptor 5 (dr5), among others. 2022-07-09 2023-08-14 mouse
Si-Ying Liu, Jian-Xu Rao, Jie Deng, Gui-Juan Zhang, Xiao-Ling Jiang, Jing Cheng, Huan Chen, Zhi-Gang Jiang, De-Lin Xu, Yi-Huai H. Feedback loop between hepatocyte nuclear factor 1α and endoplasmic reticulum stress mitigates liver injury by downregulating hepatocyte apoptosis. Scientific reports. vol 12. issue 1. 2022-07-08. PMID:35804081. hepatocyte nuclear factor alpha (hnf1α), endoplasmic reticulum (er) stress, and hepatocyte apoptosis contribute to severe acute exacerbation (sae) of liver injury. 2022-07-08 2023-08-14 Not clear
Qing Li, Xianjie Zhang, Siyuan Li, Wen Li, Yunpeng Teng, Yukai Zhou, Hongfei Xion. Carnosol alleviates sevoflurane-induced cognitive dysfunction by mediating NF-κB pathway in aged rats. Drug development research. 2022-07-05. PMID:35781309. the results showed that carnosol can improve the cognitive dysfunction and reduce neuroinflammation in aged rats induced by sev; carnosol can reduce the activation of microglia and inhibit neuronal apoptosis in aged rats induced by sev; carnosol can phosphorylate p65 and nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, alpha regulates the nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb) pathway. 2022-07-05 2023-08-14 rat
Kaori Yoriki, Taisuke Mori, Kohei Aoyama, Yosuke Tarumi, Hisashi Kataoka, Tetsuya Kokabu, Jo Kitawak. Genistein induces long-term expression of progesterone receptor regardless of estrogen receptor status and improves the prognosis of endometrial cancer patients. Scientific reports. vol 12. issue 1. 2022-06-18. PMID:35717540. genistein inhibits cell growth by inducing cell cycle arrest in g2 and apoptosis; moreover, it upregulates prolonged expression of pr-b and forkhead box protein o1, regardless of estrogen receptor alpha expression in endometrial cancer cells. 2022-06-18 2023-08-14 Not clear
Ruonan Liang, Shuaiyin Chen, Yuefei Jin, Ling Tao, Wangquan Ji, Peiyu Zhu, Dong Li, Yu Zhang, Weiguo Zhang, Guangcai Dua. The CXCL10/CXCR3 Axis Promotes Disease Pathogenesis in Mice upon CVA2 Infection. Microbiology spectrum. 2022-05-23. PMID:35604176. additionally, αcxcr3 treatment reduced viral loads and reversed the proinflammatory cytokine (interleukin 6 [il-6], tumor necrosis factor alpha [tnf-α], and il-1β) expression, apoptosis, and inflammatory cell infiltration induced by cva2. 2022-05-23 2023-08-13 mouse
Yu-Ting Sun, Jun-Hong Cai, Shan Ba. Overexpression of lncRNA HCP5 in human umbilical cord mesenchymal stem cell-derived exosomes promoted the proliferation and inhibited the apoptosis of ovarian granulosa cells via the musashi RNA-binding protein 2/oestrogen receptor alpha 1 axis. Endocrine journal. 2022-05-11. PMID:35545536. overexpression of lncrna hcp5 in human umbilical cord mesenchymal stem cell-derived exosomes promoted the proliferation and inhibited the apoptosis of ovarian granulosa cells via the musashi rna-binding protein 2/oestrogen receptor alpha 1 axis. 2022-05-11 2023-08-13 human
Ye Cao, Jiajia Zheng, Chentao L. Correction: miR-199a-3p knockdown inhibits dedifferentiated liposarcoma (DDLPS) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (CK1α). RSC advances. vol 9. issue 56. 2022-05-09. PMID:35529749. correction: mir-199a-3p knockdown inhibits dedifferentiated liposarcoma (ddlps) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (ck1α). 2022-05-09 2023-08-13 Not clear
Ye Cao, Jiajia Zheng, Chentao L. Retracted Article: miR-199a-3p knockdown inhibits dedifferentiated liposarcoma (DDLPS) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (CK1α). RSC advances. vol 9. issue 39. 2022-05-06. PMID:35519458. retracted article: mir-199a-3p knockdown inhibits dedifferentiated liposarcoma (ddlps) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (ck1α). 2022-05-06 2023-08-13 Not clear
Guo Wang, Xiaoyan Lin, Han Han, Hongxu Zhang, Xiaoli Li, Mei Feng, Chunming Jian. lncRNA H19 promotes glioblastoma multiforme development by activating autophagy by sponging miR-491-5p. Bioengineered. vol 13. issue 5. 2022-05-04. PMID:35506168. in addition, cell viability, proliferation, apoptosis and autophagy were respectively determined via cell counting kit-8 assay, clone formation assay, flow cytometry, western blotting and green fluorescent protein-microtubule-associated protein 1 light chain 3 alpha fluorescence analysis 2022-05-04 2023-08-13 Not clear
Laura Fishe. Retraction: miR-199a-3p knockdown inhibits dedifferentiated liposarcoma (DDLPS) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (CK1α). RSC advances. vol 11. issue 10. 2022-04-15. PMID:35427032. retraction: mir-199a-3p knockdown inhibits dedifferentiated liposarcoma (ddlps) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (ck1α). 2022-04-15 2023-08-13 Not clear
Meixia Yang, Jianhao Feng, Xianyong Lan, Yaru Tang, Yufang Zhang, Hongliang Zhang, Shuilian Wan. Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments. In vitro cellular & developmental biology. Animal. 2022-04-05. PMID:35378691. cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments. 2022-04-05 2023-08-13 mouse
Meixia Yang, Jianhao Feng, Xianyong Lan, Yaru Tang, Yufang Zhang, Hongliang Zhang, Shuilian Wan. Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments. In vitro cellular & developmental biology. Animal. 2022-04-05. PMID:35378691. here, we investigated the effects of cpg-odns on the cell cycle, apoptosis, and steroidogenesis in mouse granulosa cells (mgcs), in combination with inhibin alpha (1 ~ 32) fragments. 2022-04-05 2023-08-13 mouse
Meixia Yang, Jianhao Feng, Xianyong Lan, Yaru Tang, Yufang Zhang, Hongliang Zhang, Shuilian Wan. Cytosine-phosphate-guanine oligodeoxynucleotides regulate the cell cycle, apoptosis, and steroidogenesis of mouse ovarian granulosa cells by targeting inhibin alpha (1 ~ 32) fragments. In vitro cellular & developmental biology. Animal. 2022-04-05. PMID:35378691. in conclusion, this study demonstrated that cpg-odns may affect the cell cycle, apoptosis, and steroidogenesis by targeting the effects of inhibin alpha (1 ~ 32) fragments, supporting the potential role of cpg-odns in the development of granulosa cells. 2022-04-05 2023-08-13 mouse
Piaopiao Xu, Xiangling Chen, Yongping Xu, Li Fu, Yun Li, Haoyu Fu, Qing Yao, Haitian Quan, Liguang Lo. Trastuzumab in combination with PEGylated interferon-α1b exerts synergistic antitumor activity through enhanced inhibition of HER2 downstream signaling and antibody-dependent cellular cytotoxicity. American journal of cancer research. vol 12. issue 2. 2022-03-09. PMID:35261786. in this study, we report that trastuzumab in combination with pegylated interferon-α1b (ifn-α1b), a polyethylene glycol (peg)-conjugated form of a subtype of interferon alpha (ifn-α), synergistically inhibited the proliferation of her2-positive cells, including bt-474 and sk-br-3 breast cancer cells and nci-n87 gastric cancer cells, and also induced their apoptosis, but had no effect on her2-negative mda-mb-231 breast cancer cells. 2022-03-09 2023-08-13 Not clear
Rehab S Abdelrahman, Ramy A Abdelsalam, Marwa S Zaghlou. Beneficial effect of trimetazidine on folic acid-induced acute kidney injury in mice: Role of HIF-1α/HO-1. Journal of biochemical and molecular toxicology. 2022-02-22. PMID:35191561. finally, tmz amended fa-induced histopathological changes in kidneys. by mitigating functional alteration, oxidative stress, and preventing the development of inflammatory and apoptosis signals, tmz provides dose-dependent defense against fa-induced aki mainly via stimulation of hypoxia-inducible factor-1 alpha (hif-1α)/heme oxygenase-1 (ho-1) pathway. 2022-02-22 2023-08-13 mouse
Xinghui Wang, Mengyao Zhu, Juan J Loor, Qianming Jiang, Yiwei Zhu, Wei Li, Xiliang Du, Yuxiang Song, Wenwen Gao, Lin Lei, Jianguo Wang, Guowen Liu, Xinwei L. Propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating PPARG coactivator 1 alpha in hepatocytes. Journal of dairy science. 2022-02-19. PMID:35181129. propionate alleviates fatty acid-induced mitochondrial dysfunction, oxidative stress, and apoptosis by upregulating pparg coactivator 1 alpha in hepatocytes. 2022-02-19 2023-08-13 Not clear