| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Roh, A Laemmle, U Von Holzen, D Stroka, J-F Dufour, K K Hunt, D Candinas, S A Vorburge. Dual induction of PKR with E2F-1 and IFN-alpha to enhance gene therapy against hepatocellular carcinoma. Cancer gene therapy. vol 15. issue 10. 2009-01-09. PMID:18535617. |
when adcmv-e2f was combined with the pkr modifier interferon alpha (ifnalpha), pkr was additionally upregulated and both pkr activation and apoptosis were increased. |
2009-01-09 |
2023-08-12 |
human |
| Yu-Ting Yen, Hsuen-Chin Chen, Hseun-Chin Chen, Yang-Ding Lin, Chi-Chang Shieh, Betty A Wu-Hsie. Enhancement by tumor necrosis factor alpha of dengue virus-induced endothelial cell production of reactive nitrogen and oxygen species is key to hemorrhage development. Journal of virology. vol 82. issue 24. 2009-01-02. PMID:18842737. |
temporal studies showed that beginning at day 2, there was macrophage infiltration into the vicinity of the endothelium, increased tumor necrosis factor alpha (tnf-alpha) production, and endothelial cell apoptosis in the tissues. |
2009-01-02 |
2023-08-12 |
mouse |
| Hao Wu, Wei Li, Tongshan Wang, Yongqian Shu, Ping Li. Paeoniflorin suppress NF-kappaB activation through modulation of I kappaB alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 62. issue 9. 2008-12-29. PMID:18809274. |
paeoniflorin suppress nf-kappab activation through modulation of i kappab alpha and enhances 5-fluorouracil-induced apoptosis in human gastric carcinoma cells. |
2008-12-29 |
2023-08-12 |
human |
| Simone Difilippantonio, Eric Gapud, Nancy Wong, Ching-Yu Huang, Grace Mahowald, Hua Tang Chen, Michael J Kruhlak, Elsa Callen, Ferenc Livak, Michel C Nussenzweig, Barry P Sleckman, André Nussenzwei. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature. vol 456. issue 7221. 2008-12-29. PMID:18931658. |
this results in apoptosis, loss of t-cell receptor alpha locus integrity and lymphopenia. |
2008-12-29 |
2023-08-12 |
mouse |
| Sangita Manna, Tridib Chakraborty, Balaram Ghosh, Mary Chatterjee, Amalendu Panda, Sunil Srivastava, Ajay Rana, Malay Chatterje. Dietary fish oil associated with increased apoptosis and modulated expression of Bax and Bcl-2 during 7,12-dimethylbenz(alpha)anthracene-induced mammary carcinogenesis in rats. Prostaglandins, leukotrienes, and essential fatty acids. vol 79. issue 1-2. 2008-12-16. PMID:18614344. |
dietary fish oil associated with increased apoptosis and modulated expression of bax and bcl-2 during 7,12-dimethylbenz(alpha)anthracene-induced mammary carcinogenesis in rats. |
2008-12-16 |
2023-08-12 |
rat |
| Haiying Sun, Zaneta Nikolovska-Coleska, Chao-Yie Yang, Dongguang Qian, Jianfeng Lu, Su Qiu, Longchuan Bai, Yuefeng Peng, Qian Cai, Shaomeng Wan. Design of small-molecule peptidic and nonpeptidic Smac mimetics. Accounts of chemical research. vol 41. issue 10. 2008-12-16. PMID:18937395. |
it was shown that smac mimetics induce apoptosis in tumor cells by targeting ciap-1/-2 for the rapid degradation of these proteins, which leads to activation of nuclear factor kappab (nf-kappab) and production and secretion of tumor necrosis factor alpha (tnfalpha). |
2008-12-16 |
2023-08-12 |
human |
| Daria A Chudakova, Youssef H Zeidan, Brian W Wheeler, Jin Yu, Sergei A Novgorodov, Mark S Kindy, Yusuf A Hannun, Tatyana I Gud. Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity. The Journal of biological chemistry. vol 283. issue 43. 2008-12-11. PMID:18682390. |
herein we report that attachment of oligodendrocytes (ols) to fibronectin via alpha(v)beta(3) integrin receptors rendered the cells more resistant to apoptosis than the cells attached to laminin via alpha(6)beta(1) integrins. |
2008-12-11 |
2023-08-12 |
mouse |
| Daria A Chudakova, Youssef H Zeidan, Brian W Wheeler, Jin Yu, Sergei A Novgorodov, Mark S Kindy, Yusuf A Hannun, Tatyana I Gud. Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyelinase activity. The Journal of biological chemistry. vol 283. issue 43. 2008-12-11. PMID:18682390. |
both in ols and in the mouse brain, lyn selectively associates with alpha(v)beta(3) integrin, not with alpha(v)beta(5) integrin, leading to suppression of acid sphingomyelinase activity and preventing ceramide-mediated apoptosis. |
2008-12-11 |
2023-08-12 |
mouse |
| Ginny I Chen, Sally Tisayakorn, Claus Jorgensen, Lisa M D'Ambrosio, Marilyn Goudreault, Anne-Claude Gingra. PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. The Journal of biological chemistry. vol 283. issue 43. 2008-12-11. PMID:18715871. |
protein serine/threonine phosphatase 4 (pp4c) is an essential polypeptide involved in critical cellular processes such as microtubule growth and organization, dna damage checkpoint recovery, apoptosis, and tumor necrosis factor alpha signaling. |
2008-12-11 |
2023-08-12 |
Not clear |
| Rainer Gallitzendoerfer, Mekky M Abouzied, Dieter Hartmann, Radoslaw Dobrowolski, Volkmar Gieselmann, Sebastian Franke. Hepatoma-derived growth factor (HDGF) is dispensable for normal mouse development. Developmental dynamics : an official publication of the American Association of Anatomists. vol 237. issue 7. 2008-12-10. PMID:18570251. |
contrary to the reported role of hdgf as a modulator of apoptosis, similar apoptotic rates were found between wild-type and hdgf-deficient fibroblasts following tumor necrosis factor alpha (tnfalpha) -induced apoptosis or cellular stress. |
2008-12-10 |
2023-08-12 |
mouse |
| Helieh S Oz, Theresa S Che. Green-tea polyphenols downregulate cyclooxygenase and Bcl-2 activity in acetaminophen-induced hepatotoxicity. Digestive diseases and sciences. vol 53. issue 11. 2008-12-09. PMID:18373199. |
apap also caused severe centrilobular apoptosis and necrosis accompanied by leukocyte infiltration and marked elevations in the hepatic enzyme, alanine aminotransferase (alt) released from damaged hepatocytes, and cytokine tumor necrosis factor alpha (tnf-alpha). |
2008-12-09 |
2023-08-12 |
mouse |
| Javier Beaumont, Teresa Arias, Susana Ravassa, Javier Díe. Overexpression of human truncated peroxisome proliferator-activated receptor alpha induces apoptosis in HL-1 cardiomyocytes. Cardiovascular research. vol 79. issue 3. 2008-12-02. PMID:18440986. |
overexpression of human truncated peroxisome proliferator-activated receptor alpha induces apoptosis in hl-1 cardiomyocytes. |
2008-12-02 |
2023-08-12 |
human |
| Javier Beaumont, Teresa Arias, Susana Ravassa, Javier Díe. Overexpression of human truncated peroxisome proliferator-activated receptor alpha induces apoptosis in HL-1 cardiomyocytes. Cardiovascular research. vol 79. issue 3. 2008-12-02. PMID:18440986. |
our goal was to analyse whether truncated peroxisome proliferator-activated receptor alpha (pparalpha) overexpression induces apoptosis of cardiomyocytes. |
2008-12-02 |
2023-08-12 |
human |
| Ying-Xin Qi, Ming-Juan Qu, Ding-Kun Long, Bo Liu, Qing-Ping Yao, Shu Chien, Zong-Lai Jian. Rho-GDP dissociation inhibitor alpha downregulated by low shear stress promotes vascular smooth muscle cell migration and apoptosis: a proteomic analysis. Cardiovascular research. vol 80. issue 1. 2008-12-02. PMID:18540023. |
rho-gdp dissociation inhibitor alpha downregulated by low shear stress promotes vascular smooth muscle cell migration and apoptosis: a proteomic analysis. |
2008-12-02 |
2023-08-12 |
Not clear |
| Elizabeth S Taglauer, Ann S Trikhacheva, Joyce G Slusser, Margaret G Petrof. Expression and function of PDCD1 at the human maternal-fetal interface. Biology of reproduction. vol 79. issue 3. 2008-11-26. PMID:18550794. |
compared with empty vector-transfected cells, cd274-transfected jar cells caused a significant suppression of interferon gamma and tumor necrosis factor alpha production by cd4+ (p < 0.05) but not cd8 bright t cells, while having no effect on secretion of il10 or t cell apoptosis. |
2008-11-26 |
2023-08-12 |
human |
| Clotilde Castaldo, Franca Di Meglio, Daria Nurzynska, Gianpaolo Romano, Ciro Maiello, Ciro Bancone, Patrick Müller, Michael Böhm, Maurizio Cotrufo, Stefania Montagnan. CD117-positive cells in adult human heart are localized in the subepicardium, and their activation is associated with laminin-1 and alpha6 integrin expression. Stem cells (Dayton, Ohio). vol 26. issue 7. 2008-11-18. PMID:18436868. |
signaling mediated by alpha(6) integrin was implicated in the migration and protection from apoptosis, as documented by transfection with specific small interfering rna. |
2008-11-18 |
2023-08-12 |
human |
| Li-Shu Wang, Yi-Wen Huang, Suling Liu, Pearlly Yan, Young C Li. Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. BMC cancer. vol 8. 2008-11-18. PMID:18652667. |
conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. |
2008-11-18 |
2023-08-12 |
human |
| Martijn Schenning, Joachim Goedhart, Theodorus W J Gadella, Diana Avram, Karel W A Wirtz, Gerry T Snoe. The anti-apoptotic activity associated with phosphatidylinositol transfer protein alpha activates the MAPK and Akt/PKB pathway. Biochimica et biophysica acta. vol 1783. issue 10. 2008-11-13. PMID:18501717. |
snoek, phosphatidylinositol transfer protein alpha regulates growth and apoptosis of nih3t3 cells: involvement of a cannabinoid 1-like receptor, j. lipid res. |
2008-11-13 |
2023-08-12 |
mouse |
| Andrew J Steele, Archibald G Prentice, A Victor Hoffbrand, Birunthini C Yogashangary, Stephen M Hart, Elisabeth P Nacheva, Julie D Howard-Reeves, Veronique M Duke, Panagiotis D Kottaridis, Kate Cwynarski, Lyubomir T Vassilev, R Gitendra Wickremasingh. p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism. Blood. vol 112. issue 9. 2008-11-12. PMID:18682598. |
surprisingly, pifithrin alpha dramatically augmented apoptosis induction by p53-elevating agents and also accelerated the proapoptotic conformation change of the bax protein. |
2008-11-12 |
2023-08-12 |
Not clear |
| Theocharis Panaretakis, Linn Hjortsberg, Katja Pokrovskaja Tamm, Ann-Charlotte Björklund, Bertrand Joseph, Dan Grandé. Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin. Molecular biology of the cell. vol 19. issue 1. 2008-11-10. PMID:17942603. |
interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-jun nh2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin. |
2008-11-10 |
2023-08-12 |
Not clear |