Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Fengjian Chen, Xunping Jiang, Xiuping Chen, Guiqiong Liu, Jiatong Din. Effects of downregulation of inhibin alpha gene expression on apoptosis and proliferation of goose granulosa cells. Journal of genetics and genomics = Yi chuan xue bao. vol 34. issue 12. 2009-04-24. PMID:18155623. |
effects of downregulation of inhibin alpha gene expression on apoptosis and proliferation of goose granulosa cells. |
2009-04-24 |
2023-08-12 |
Not clear |
Fengjian Chen, Xunping Jiang, Xiuping Chen, Guiqiong Liu, Jiatong Din. Effects of downregulation of inhibin alpha gene expression on apoptosis and proliferation of goose granulosa cells. Journal of genetics and genomics = Yi chuan xue bao. vol 34. issue 12. 2009-04-24. PMID:18155623. |
to study the genetic effects of inhibin alpha on apoptosis and proliferation of goose granulosa cells cultured in vitro, two rna interference (rnai) expression vectors, psirna-inh alpha 1 and psirna-inh alpha 2, were constructed to knock down inhibin alpha gene expression. |
2009-04-24 |
2023-08-12 |
Not clear |
Fengjian Chen, Xunping Jiang, Xiuping Chen, Guiqiong Liu, Jiatong Din. Effects of downregulation of inhibin alpha gene expression on apoptosis and proliferation of goose granulosa cells. Journal of genetics and genomics = Yi chuan xue bao. vol 34. issue 12. 2009-04-24. PMID:18155623. |
the results showed that the expression level of inhibin alpha in the rnai group were decreased 30%-40% than those in the control groups (p < 0.05) and the apoptosis indexes and proliferation indexes in the rnai groups were significantly higher than those in the control groups (p < 0.05). |
2009-04-24 |
2023-08-12 |
Not clear |
Fengjian Chen, Xunping Jiang, Xiuping Chen, Guiqiong Liu, Jiatong Din. Effects of downregulation of inhibin alpha gene expression on apoptosis and proliferation of goose granulosa cells. Journal of genetics and genomics = Yi chuan xue bao. vol 34. issue 12. 2009-04-24. PMID:18155623. |
these results indicate that inhibin alpha has antagonistic effect on granulosa cell apoptosis. |
2009-04-24 |
2023-08-12 |
Not clear |
Victoria M Rimkunas, Mark J Graham, Rosanne M Crooke, Laura Liscu. TNF-{alpha} plays a role in hepatocyte apoptosis in Niemann-Pick type C liver disease. Journal of lipid research. vol 50. issue 2. 2009-04-20. PMID:18815434. |
tnf-{alpha} plays a role in hepatocyte apoptosis in niemann-pick type c liver disease. |
2009-04-20 |
2023-08-12 |
mouse |
Victoria M Rimkunas, Mark J Graham, Rosanne M Crooke, Laura Liscu. TNF-{alpha} plays a role in hepatocyte apoptosis in Niemann-Pick type C liver disease. Journal of lipid research. vol 50. issue 2. 2009-04-20. PMID:18815434. |
we hypothesize that tumor necrosis factor alpha (tnf-alpha), which is involved in both proinflammatory and apoptotic signaling cascades, is a key mediator of inflammation, apoptosis, and fibrosis in npc liver disease. |
2009-04-20 |
2023-08-12 |
mouse |
Miran Seo, Hyo-Jung Nam, So-Young Kim, Yong-Sung Juhn. Inhibitory heterotrimeric GTP-binding proteins inhibit hydrogen peroxide-induced apoptosis by up-regulation of Bcl-2 via NF-kappaB in H1299 human lung cancer cells. Biochemical and biophysical research communications. vol 381. issue 2. 2009-04-20. PMID:19233129. |
the stable expression of constitutively active alpha subunits of gi1 (galphai1ql), gi2, or gi3 inhibited hydrogen peroxide-induced apoptosis. |
2009-04-20 |
2023-08-12 |
human |
Kun-Hung Shen, Cheng-Hsien Lin, Hsiu-Kang Chang, Wei-Chun Chen, Sheng-Hsien Che. Premarin can act via estrogen receptors to rescue mice from heatstroke-induced lethality. Shock (Augusta, Ga.). vol 30. issue 6. 2009-04-16. PMID:18496235. |
heat-induced apoptosis, as indicated by terminal deoxynucleotidyl-transferase-mediated alpha udp-biotin nick end-labeling staining, in the spleen, liver, and kidney were significantly reduced by premarin. |
2009-04-16 |
2023-08-12 |
mouse |
Jun-ichi Hirata, Joji Kotani, Michiko Aoyama, Shin-ichiro Kashiwamura, Haruyasu Ueda, Yasuhiro Kuroda, Makoto Usami, Haruki Okamura, Seishiro Marukaw. A role for IL-18 in human neutrophil apoptosis. Shock (Augusta, Ga.). vol 30. issue 6. 2009-04-16. PMID:18520705. |
thus, human neutrophils can express mrna for il-18 receptors alpha and beta, and il-18, like lps, inhibits neutrophil apoptosis by activating pi3k and erk pathways but not p38mapk. |
2009-04-16 |
2023-08-12 |
human |
Takeshi Kurosawa, Hiroyuki Nakamura, Erika Yamaura, Hiromichi Fujino, Yasuo Matsuzawa, Tatsuo Kawashima, Toshihiko Murayam. Cytotoxicity induced by inhibition of thioredoxin reductases via multiple signaling pathways: role of cytosolic phospholipase A(2)alpha-dependent and -independent release of arachidonic acid. Journal of cellular physiology. vol 219. issue 3. 2009-04-16. PMID:19170071. |
treatment with an inhibitor of p38 kinase, a downstream enzyme of the apoptosis signal-regulating kinase 1 pathway, and pyrrophenone (an inhibitor of alpha-type cytosolic phospholipase a(2), cpla(2)alpha) partially but significantly decreased the dncb-induced release of aa and cell death. |
2009-04-16 |
2023-08-12 |
mouse |
Shang-Pang Huang, Jung-Chou Chen, Chih-Chung Wu, Chi-Tsai Chen, Nou-Ying Tang, Yung-Tsuan Ho, Chyi Lo, Jink-Pin Lin, Jing-Gung Chung, Jaung-Geng Li. Capsaicin-induced apoptosis in human hepatoma HepG2 cells. Anticancer research. vol 29. issue 1. 2009-04-16. PMID:19331147. |
the alpha psi(m) significantly decreased after capsaicin treatment for 24 h. co-treatment of hepg2 cells with capsaicin and bapta (an intracellular ca2+ chelator) significantly reduced intracellular ca2+ levels, prevented alpha psi(m) disruption and inhibited apoptosis induction. |
2009-04-16 |
2023-08-12 |
human |
Shang-Pang Huang, Jung-Chou Chen, Chih-Chung Wu, Chi-Tsai Chen, Nou-Ying Tang, Yung-Tsuan Ho, Chyi Lo, Jink-Pin Lin, Jing-Gung Chung, Jaung-Geng Li. Capsaicin-induced apoptosis in human hepatoma HepG2 cells. Anticancer research. vol 29. issue 1. 2009-04-16. PMID:19331147. |
the caspase-3 activity significantly increased after capsaicin treatment for 24 h. our results indicated that the capsaicin-induced apoptosis in hepg2 cells may result from the elevation of intracellular ca2+ production, ros, disruption of alpha psi(m), regulation of bcl-2 family protein expression and caspase-3 activity. |
2009-04-16 |
2023-08-12 |
human |
Christian Rust, Nadine Wild, Carina Bernt, Timo Vennegeerts, Ralf Wimmer, Ulrich Beuer. Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent. The Journal of biological chemistry. vol 284. issue 5. 2009-04-07. PMID:19017654. |
in addition, gcdca-induced apoptosis was reduced by 50% in fadd-deficient hepg2-ntcp cells, whereas apoptosis induced by tumor necrosis factor alpha was reduced by 90%. |
2009-04-07 |
2023-08-12 |
human |
Sylwia Michlewska, Ian Dransfield, Ian L Megson, Adriano G Ross. Macrophage phagocytosis of apoptotic neutrophils is critically regulated by the opposing actions of pro-inflammatory and anti-inflammatory agents: key role for TNF-alpha. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 23. issue 3. 2009-04-01. PMID:18971259. |
although the powerful proinflammatory agents lipopolysaccharide (lps) and tumor necrosis factor alpha (tnf-alpha) influence rates of inflammatory cell apoptosis, little is known about their effects on efferocytosis. |
2009-04-01 |
2023-08-12 |
Not clear |
S Mitola, V Sorbello, E Ponte, E Copreni, C Mascia, M Bardessono, M Goia, F Biasi, M Conese, G Poli, F Bussolino, V De Ros. Tumor necrosis factor-alpha in airway secretions from cystic fibrosis patients upregulate endothelial adhesion molecules and induce airway epithelial cell apoptosis: implications for cystic fibrosis lung disease. International journal of immunopathology and pharmacology. vol 21. issue 4. 2009-03-30. PMID:19144271. |
ssp obtained from cf patients, especially at the time of an acute exacerbation, induced a) an upregulation of endothelial adhesion molecules on cultured hmecs that was associated with an increase of neutrophil adhesion to these cells, and was mediated at least in part by tnf-alpha and il-1 and b) apoptosis of airway epithelial cells, mainly activated by tnf- alpha pathway. |
2009-03-30 |
2023-08-12 |
human |
Peng Qu, Hong Du, Yuan Li, Cong Ya. Myeloid-specific expression of Api6/AIM/Sp alpha induces systemic inflammation and adenocarcinoma in the lung. Journal of immunology (Baltimore, Md. : 1950). vol 182. issue 3. 2009-03-30. PMID:19155514. |
to study the functional role of apoptosis inhibition of myeloid lineage cells in tumor formation, apoptosis inhibitor 6 (api6/aim/sp alpha) was overexpressed in a myeloid-specific c-fms-rtta/(teto)(7)-cmv-api6 bitransgenic mouse model under the control of the c-fms promoter/intron 2. |
2009-03-30 |
2023-08-12 |
mouse |
M Gudur Valmiki, J W Ramo. Death effector domain-containing proteins. Cellular and molecular life sciences : CMLS. vol 66. issue 5. 2009-03-27. PMID:18989622. |
these proteins are particularly associated with the regulation of apoptosis and proliferation mediated by the tumor necrosis factor alpha (tnfalpha) receptor family. |
2009-03-27 |
2023-08-12 |
Not clear |
H M Habib, T E Taher, D A Isenberg, R A Magee. Enhanced propensity of T lymphocytes in patients with systemic lupus erythematosus to apoptosis in the presence of tumour necrosis factor alpha. Scandinavian journal of rheumatology. vol 38. issue 2. 2009-03-26. PMID:19110660. |
enhanced propensity of t lymphocytes in patients with systemic lupus erythematosus to apoptosis in the presence of tumour necrosis factor alpha. |
2009-03-26 |
2023-08-12 |
Not clear |
Shu-Fen Liou, Hung-Hong Lin, Jyh-Chong Liang, Ing-Jun Chen, Jwu-Lai Ye. Inhibition of human prostate cancer cells proliferation by a selective alpha1-adrenoceptor antagonist labedipinedilol-A involves cell cycle arrest and apoptosis. Toxicology. vol 256. issue 1-2. 2009-03-24. PMID:19056458. |
in this research, we conducted an in vitro analysis to evaluate the prostate cancer cells response to labedipinedilol-a in order to determine the effect of this selective alpha(1)-adrenoceptor antagonist to suppress prostate cancer cell growth by affecting cell proliferation and apoptosis. |
2009-03-24 |
2023-08-12 |
human |
Jin-Young Han, Sara A Miller, Teresa M Wolfe, Hoda Pourhassan, Keith R Jerom. Cell type-specific induction and inhibition of apoptosis by Herpes Simplex virus type 2 ICP10. Journal of virology. vol 83. issue 6. 2009-03-24. PMID:19116254. |
hsv-2 icp10 gene expression is sufficient to induce apoptosis in jurkat cells, while its expression protects epithelial hep-2 cells from apoptosis triggered by cycloheximide and tumor necrosis factor alpha. |
2009-03-24 |
2023-08-12 |
Not clear |