| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hung-Chuan Pan, Fu-Chou Cheng, Chun-Jung Chen, Shu-Zhen Lai, Mu-Jung Liu, Ming-Hong Chang, Yeou-Chih Wang, Dar-Yu Yang, Shu-Peng H. Dietary supplement with fermented soybeans, natto, improved the neurobehavioral deficits after sciatic nerve injury in rats. Neurological research. vol 31. issue 5. 2009-08-10. PMID:19309538. |
sciatic nerve crush injury induced elevation of tumor necrosis factor alpha (tnf-alpha) production and caused apoptosis. |
2009-08-10 |
2023-08-12 |
rat |
| Yoshihiro Suzuki, Tetsuro Yoshimaru, Toshio Inoue, Chisei R. Ca v 1.2 L-type Ca2+ channel protects mast cells against activation-induced cell death by preventing mitochondrial integrity disruption. Molecular immunology. vol 46. issue 11-12. 2009-08-04. PMID:19447492. |
moreover, blockade of the expression of the alpha(1c) subunit of ca(v)1.2 ltcc using small-interfering rna strongly augmented fc epsilon ri-mediated apoptosis, mitochondrial integrity, and mitochondrial ca(2+) collapse, and abolished the protective effects of (s)-bayk8644 against tg-induced apoptosis. |
2009-08-04 |
2023-08-12 |
Not clear |
| Krystina B Hazelgrove, Robert S Flynn, Li-Ya Qiao, John R Grider, John F Kuemmerl. Endogenous IGF-I and alpha v beta3 integrin ligands regulate increased smooth muscle growth in TNBS-induced colitis. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 6. 2009-07-30. PMID:19359426. |
the changes in proliferation and apoptosis were reversed by an igf-i receptor tyrosine kinase inhibitor or an alpha(v)beta(3) integrin antagonist. |
2009-07-30 |
2023-08-12 |
rat |
| Krystina B Hazelgrove, Robert S Flynn, Li-Ya Qiao, John R Grider, John F Kuemmerl. Endogenous IGF-I and alpha v beta3 integrin ligands regulate increased smooth muscle growth in TNBS-induced colitis. American journal of physiology. Gastrointestinal and liver physiology. vol 296. issue 6. 2009-07-30. PMID:19359426. |
the results suggest that smooth muscle hyperplasia in tnbs-induced colitis partly results from the upregulation of endogenous igf-i and ligands of alpha(v)beta(3) integrin that mediate increased smooth muscle cell proliferation and decreased apoptosis. |
2009-07-30 |
2023-08-12 |
rat |
| Walee Chamulitrat, Jürgen Burhenne, Tobias Rehlen, Anita Pathil, Wolfgang Stremme. Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent. Hepatology (Baltimore, Md.). vol 50. issue 1. 2009-07-28. PMID:19496180. |
cytoprotection by udca-lpe was tested in starvation and tumor necrosis factor alpha (tnf-alpha) apoptosis models using hepg2 cells. |
2009-07-28 |
2023-08-12 |
mouse |
| Hongyan Du, Xiang Huang, Suihai Wang, Yingsong Wu, Weiwen Xu, Ming L. PSMA7, a potential biomarker of diseases. Protein and peptide letters. vol 16. issue 5. 2009-07-27. PMID:19442227. |
proteasome subunit alpha type 7(psma7) is an alpha-type subunit of the 20s proteasome core complex and participates in degrading proteins through ubiquitin-proteasome pathway (upp) which plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. |
2009-07-27 |
2023-08-12 |
Not clear |
| Brian Skaug, Xiaomo Jiang, Zhijian J Che. The role of ubiquitin in NF-kappaB regulatory pathways. Annual review of biochemistry. vol 78. 2009-07-23. PMID:19489733. |
particular emphasis is given to proteasome-independent functions of ubiquitin, specifically its role in the activation of protein kinase complexes and in coordination of cell survival and apoptosis signals downstream of tumor necrosis factor alpha (tnfalpha). |
2009-07-23 |
2023-08-12 |
Not clear |
| Maria J Comin, Gabriella Czifra, Noemi Kedei, Andrea Telek, Nancy E Lewin, Sofiya Kolusheva, Julia F Velasquez, Ryan Kobylarz, Raz Jelinek, Peter M Blumberg, Victor E Marque. Conformationally constrained analogues of diacylglycerol (DAG). 31. Modulation of the biological properties of diacylgycerol lactones (DAG-lactones) containing rigid-rod acyl groups separated from the core lactone by spacer units of different lengths. Journal of medicinal chemistry. vol 52. issue 10. 2009-07-17. PMID:19379015. |
the kinetics and site of translocation for the pkc isozymes alpha and delta upon treatment with the compounds were also studied as well as the early response of erk phosphorylation and the late response of induction of apoptosis in the human prostatic carcinoma cell line lncap. |
2009-07-17 |
2023-08-12 |
human |
| Deepa S De Silva, Richard M Wilson, Christoph Hutchinson, Peter C Ip, Anthony G Garcia, Steve Lancel, Masa Ito, David R Pimentel, Flora Sa. Fenofibrate inhibits aldosterone-induced apoptosis in adult rat ventricular myocytes via stress-activated kinase-dependent mechanisms. American journal of physiology. Heart and circulatory physiology. vol 296. issue 6. 2009-07-17. PMID:19395558. |
therefore, involvement of jnk mapk-dependent mitochondrial death pathway mediates arvm aldosterone-induced apoptosis and is inhibited by fenofibrate, a peroxisome proliferator-activated receptor (ppar)alpha ligand. |
2009-07-17 |
2023-08-12 |
rat |
| Yoon Jung Choi, Jung-Min Oh, So-Young Kim, Miran Seo, Yong-Sung Juhn. Stimulatory heterotrimeric GTP-binding protein augments cisplatin-induced apoptosis by upregulating Bak expression in human lung cancer cells. Cancer science. vol 100. issue 6. 2009-07-08. PMID:19320642. |
overexpression of the constitutively active alpha subunit of gs (galphasql) in a549 human lung cancer cells increased cisplatin-induced apoptosis, and knockdown of galphas with small hairpin rna decreased the percentage of apoptotic cells. |
2009-07-08 |
2023-08-12 |
human |
| Salahuddin Ahmed, Matthew D Silverman, Hubert Marotte, Kevin Kwan, Natalie Matuszczak, Alisa E Koc. Down-regulation of myeloid cell leukemia 1 by epigallocatechin-3-gallate sensitizes rheumatoid arthritis synovial fibroblasts to tumor necrosis factor alpha-induced apoptosis. Arthritis and rheumatism. vol 60. issue 5. 2009-06-30. PMID:19404960. |
overexpression of the antiapoptotic protein myeloid cell leukemia 1 (mcl-1) in rheumatoid arthritis (ra) synovial fibroblasts is a major cause of their resistance to tumor necrosis factor alpha (tnfalpha)-induced apoptosis. |
2009-06-30 |
2023-08-12 |
Not clear |
| YanHe Lue, Christina Wang, YuGui Cui, XingHai Wang, JiaHao Sha, ZuoMin Zhou, Jun Xu, Charles Wang, Amiya P Sinha Hikim, Ronald S Swerdlof. Levonorgestrel enhances spermatogenesis suppression by testosterone with greater alteration in testicular gene expression in men. Biology of reproduction. vol 80. issue 3. 2009-06-25. PMID:19074003. |
both tu and tu + lng administration suppressed gene expression of insulin-like 3; cytochrome p450, family 17, subfamily a1 in leydig cells; and inhibin alpha in sertoli cells; they increased proapoptotic transcripts bcl2-like 14, insulin-like growth factor-binding protein 3; and they decreased x-linked inhibitor of apoptosis protein. |
2009-06-25 |
2023-08-12 |
human |
| Hui Zhang, Gary G Meadow. Exogenous IL-15 in combination with IL-15R alpha rescues natural killer cells from apoptosis induced by chronic alcohol consumption. Alcoholism, clinical and experimental research. vol 33. issue 3. 2009-06-19. PMID:19120059. |
exogenous il-15 in combination with il-15r alpha rescues natural killer cells from apoptosis induced by chronic alcohol consumption. |
2009-06-19 |
2023-08-12 |
mouse |
| Chun-Hsien Chu, Bor-Show Tzang, Li-Mien Chen, Chung-Jung Liu, Fuu-Jen Tsai, Chang-Hai Tsai, James A Lin, Wei-Wen Kuo, Da-Tian Bau, Chun-Hsu Yao, Chih-Yang Huan. Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells. Endocrinology. vol 150. issue 6. 2009-06-18. PMID:19095737. |
activation of insulin-like growth factor ii receptor induces mitochondrial-dependent apoptosis through g(alpha)q and downstream calcineurin signaling in myocardial cells. |
2009-06-18 |
2023-08-12 |
rat |
| Nora Engel, Jennifer S Tront, Toyin Erinle, Nghi Nguyen, Keith E Latham, Carmen Sapienza, Barbara Hoffman, Dan A Lieberman. Conserved DNA methylation in Gadd45a(-/-) mice. Epigenetics. vol 4. issue 2. 2009-06-17. PMID:19229137. |
gadd45a (growth arrest and dna-damage-inducible protein 45 alpha) plays a pivotal role in cellular stress responses and is implicated in dna repair, cell cycle arrest and apoptosis. |
2009-06-17 |
2023-08-12 |
mouse |
| Ari M Chow, Rohan Steel, Robin L Anderso. Hsp72 chaperone function is dispensable for protection against stress-induced apoptosis. Cell stress & chaperones. vol 14. issue 3. 2009-06-02. PMID:18819021. |
in this study, we show that hsp72 mutants with a functional substrate-binding domain but lacking chaperone activity retain their ability to protect cells against apoptosis induced by heat and tumor necrosis factor alpha. |
2009-06-02 |
2023-08-12 |
Not clear |
| Mohamed Hassan, Denis Selimovic, Hanan Ghozlan, Ola Abdel-kade. Hepatitis C virus core protein triggers hepatic angiogenesis by a mechanism including multiple pathways. Hepatology (Baltimore, Md.). vol 49. issue 5. 2009-06-02. PMID:19235829. |
in addition, regulated expression of core protein in hepg2 or huh7 cells was found to induce expression and activation of the transcription factor e2f1 and apoptosis signal-regulating kinase 1 (ask1), activation of c-jun-n-terminal kinase (jnk) and p38, and extracellular-regulated kinase (erk), and transcription factors activator protein 1 (ap-1), activating transcription factor 2 (atf-2), cyclic adenosine monophosphate response element binding (creb), e2f1, hypoxia inducing factor 1 alpha (hif-1alpha), and specificity protein 1. |
2009-06-02 |
2023-08-12 |
Not clear |
| Sadhna Sharma, Monika Sharma, Mridula Bos. Mycobacterium tuberculosis infection of human monocyte-derived macrophages leads to apoptosis of T cells. Immunology and cell biology. vol 87. issue 3. 2009-05-11. PMID:19104503. |
significantly higher no and tnf- alpha levels suggested an association of the soluble factors with apoptosis of nonspecifically activated t cells. |
2009-05-11 |
2023-08-12 |
human |
| Jian Guang Lu, Ya Nan Sun, Chao Wang, De Jun Jin, Ming Li. Role of the alpha v-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 266. issue 1. 2009-05-05. PMID:18427826. |
role of the alpha v-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation. |
2009-05-05 |
2023-08-12 |
Not clear |
| Jian Guang Lu, Ya Nan Sun, Chao Wang, De Jun Jin, Ming Li. Role of the alpha v-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. vol 266. issue 1. 2009-05-05. PMID:18427826. |
the objective of this study was to investigate the role of alpha v-integrin subunit (itgav, cd51) in invasion and metastasis of the laryngeal and hypopharyngeal squamous cell carcinomas and to evaluate whether an antisense oligonucleotide sequence (asons) targeting itgav gene can result in proliferative inhibition and induce to apoptosis of laryngeal carcinoma cell lines (hep-2). |
2009-05-05 |
2023-08-12 |
Not clear |