| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elzbieta Pluskota, Dmitry A Soloviev, Dorota Szpak, Christian Weber, Edward F Plo. Neutrophil apoptosis: selective regulation by different ligands of integrin alphaMbeta2. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 5. 2008-09-15. PMID:18714035. |
alpha(m)beta(2) is reported either to delay or accelerate neutrophil apoptosis, but the mechanisms by which this integrin can support such diametrically opposed responses are poorly understood. |
2008-09-15 |
2023-08-12 |
Not clear |
| Elzbieta Pluskota, Dmitry A Soloviev, Dorota Szpak, Christian Weber, Edward F Plo. Neutrophil apoptosis: selective regulation by different ligands of integrin alphaMbeta2. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 5. 2008-09-15. PMID:18714035. |
the abilities of closely related alpha(m)beta(2) ligands, plasminogen and angiostatin, derived from plasminogen, as well as fibrinogen and its two derivative alpha(m)beta(2) recognition peptides, p1 and p2-c, differed markedly in their effects on neutrophil apoptosis. |
2008-09-15 |
2023-08-12 |
Not clear |
| Hajime Kin, Ning-Ping Wang, James Mykytenko, James Reeves, Jeremiah Deneve, Rong Jiang, Amanda J Zatta, Robert A Guyton, Jakob Vinten-Johansen, Zhi-Qing Zha. Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release. Shock (Augusta, Ga.). vol 29. issue 6. 2008-09-09. PMID:18496137. |
inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa b translocation and tnf alpha release. |
2008-09-09 |
2023-08-12 |
rat |
| Jay R Radke, Zeba K Siddiqui, Tanya A Miura, John M Routes, James L Coo. E1A oncogene enhancement of caspase-2-mediated mitochondrial injury sensitizes cells to macrophage nitric oxide-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 12. 2008-09-05. PMID:18523293. |
the adenovirus e1a oncogene induces innate immune rejection of tumors by sensitizing tumor cells to apoptosis in response to injuries, such as those inflicted by macrophage-produced tnf alpha and no. |
2008-09-05 |
2023-08-12 |
mouse |
| David R Grubb, Oliver Vasilevski, Huy Huynh, Elizabeth A Woodcoc. The extreme C-terminal region of phospholipase Cbeta1 determines subcellular localization and function; the "b" splice variant mediates alpha1-adrenergic receptor responses in cardiomyocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 22. issue 8. 2008-09-03. PMID:18390926. |
in cardiomyocytes, responses initiated by alpha(1)-adrenergic receptor activation involve only plcbeta1b, and the selective targeting of this splice variant to the sarcolemma provides a potential therapeutic target to reduce hypertrophy, apoptosis, and arrhythmias. |
2008-09-03 |
2023-08-12 |
Not clear |
| Hai-ping Jiang, Rong-yue Teng, Qi Wang, Xing Zhang, Hao-hao Wang, Jiang Cao, Li-song Ten. Estrogen receptor alpha variant ERalpha46 mediates growth inhibition and apoptosis of human HT-29 colon adenocarcinoma cells in the presence of 17beta-oestradiol. Chinese medical journal. vol 121. issue 11. 2008-09-02. PMID:18706253. |
estrogen receptor alpha variant eralpha46 mediates growth inhibition and apoptosis of human ht-29 colon adenocarcinoma cells in the presence of 17beta-oestradiol. |
2008-09-02 |
2023-08-12 |
human |
| Boel De Paepe, Guy G Brusselle, Tania Maes, Kim K Creus, Sophie D'hose, Nele D'Haese, Ken R Bracke, An I D'hulst, Guy F Joos, Jan L De Bleecke. TNF alpha receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice. Acta neuropathologica. vol 115. issue 6. 2008-08-26. PMID:18309502. |
cs-induced apoptosis was observed in all genotypes, while a significant reduction of cross-sectional areas of myofibres was present only in tnf alpha r2ko mice. |
2008-08-26 |
2023-08-12 |
mouse |
| Boel De Paepe, Guy G Brusselle, Tania Maes, Kim K Creus, Sophie D'hose, Nele D'Haese, Ken R Bracke, An I D'hulst, Guy F Joos, Jan L De Bleecke. TNF alpha receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice. Acta neuropathologica. vol 115. issue 6. 2008-08-26. PMID:18309502. |
our data suggest that the skeletal muscle manifestations associated with this murine copd model are under complex regulation by both tnfalpha receptors, but that tnf alpha r2 may be the most important determinant for the outcome of cs-induced myofibre apoptosis. |
2008-08-26 |
2023-08-12 |
mouse |
| Shoucheng Ning, Jeffrey A Nemeth, Rebecca L Hanson, Kevin Forsythe, Susan J Kno. Anti-integrin monoclonal antibody CNTO 95 enhances the therapeutic efficacy of fractionated radiation therapy in vivo. Molecular cancer therapeutics. vol 7. issue 6. 2008-08-22. PMID:18566227. |
immunohistochemistry studies showed that the combined use of cnto 95 and radiation reduced the alpha(v) integrin and vascular endothelial growth factor receptor expression and the microvessel density and increased apoptosis in tumor cells and the tumor microenvironment. |
2008-08-22 |
2023-08-12 |
mouse |
| Sai-Juan Chen, Li-Juan Chen, Guang-Biao Zho. [Basic and clinical studies of the gene product-targeting therapy based on leukemogenesis--editorial]. Zhongguo shi yan xue ye xue za zhi. vol 13. issue 1. 2008-08-18. PMID:15748426. |
taken together, atra and as(2)o(3) target the transcription factor pml-rar alpha, the former by retinoic acid receptor and the latter by pml sumolization, both induce pml-rar alpha degradation and apl cells differentiation and apoptosis. |
2008-08-18 |
2023-08-12 |
mouse |
| Dmitri V Rozanov, Alexei Y Savinov, Roy Williams, Kang Liu, Vladislav S Golubkov, Stan Krajewski, Alex Y Strongi. Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer. Cancer research. vol 68. issue 11. 2008-08-15. PMID:18519667. |
these genes included regulators of energy metabolism (nnt), trafficking and membrane fusion (slco2a1 and anxa7), signaling and transcription (nr3c1, jag1, pi3k delta, and ck2 alpha), chromatin rearrangement (smarca1), cell division (stk38/ndr1), apoptosis (dapk1), and mrna splicing (snrpb2). |
2008-08-15 |
2023-08-12 |
human |
| James E Vince, Diep Chau, Bernard Callus, W Wei-Lynn Wong, Christine J Hawkins, Pascal Schneider, Mark McKinlay, Christopher A Benetatos, Stephen M Condon, Srinivas K Chunduru, George Yeoh, Robert Brink, David L Vaux, John Silk. TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha. The Journal of cell biology. vol 182. issue 1. 2008-08-08. PMID:18606850. |
synthetic inhibitor of apoptosis (iap) antagonists induce degradation of iap proteins such as cellular iap1 (ciap1), activate nuclear factor kappab (nf-kappab) signaling, and sensitize cells to tumor necrosis factor alpha (tnfalpha). |
2008-08-08 |
2023-08-12 |
Not clear |
| Jonathan D Ashwel. TWEAKing death. The Journal of cell biology. vol 182. issue 1. 2008-08-08. PMID:18606854. |
smac mimetics (inhibitor of apoptosis [iap] antagonists) are synthetic reagents that kill susceptible tumor cells by inducing degradation of cellular iap (ciap) 1 and ciap2, nuclear factor kappab activation, tumor necrosis factor (tnf) alpha production, tnf receptor 1 occupancy, and caspase-8 activation. |
2008-08-08 |
2023-08-12 |
Not clear |
| Ping Ouyancg, Bin Zhang, Wei-jian Bei, Wen-yan Lai, Wen-lie Peng, Ding-li X. [Effects of flavone from leaves of Diospyros kaki on expression of apoptosis signal-regulating kinase 1 and rat vascular smooth muscle cells proliferation by tumor necrosis factor alpha in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. vol 30. issue 7. 2008-08-04. PMID:17944194. |
[effects of flavone from leaves of diospyros kaki on expression of apoptosis signal-regulating kinase 1 and rat vascular smooth muscle cells proliferation by tumor necrosis factor alpha in vitro]. |
2008-08-04 |
2023-08-12 |
rat |
| Ping Ouyancg, Bin Zhang, Wei-jian Bei, Wen-yan Lai, Wen-lie Peng, Ding-li X. [Effects of flavone from leaves of Diospyros kaki on expression of apoptosis signal-regulating kinase 1 and rat vascular smooth muscle cells proliferation by tumor necrosis factor alpha in vitro]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. vol 30. issue 7. 2008-08-04. PMID:17944194. |
to observe the effects of flavone from leaves of diospyros kaki on expression of apoptosis signal-regulating kinase 1 (ask1) and rat vascular smooth muscle cells (vsmcs) proliferation by tumor necrosis factor alpha in vitro. |
2008-08-04 |
2023-08-12 |
rat |
| Marcos C Dias, Maria A M Rodrigues, Maria C H Reimberg, Luís F Barbisa. Protective effects of Ginkgo biloba against rat liver carcinogenesis. Chemico-biological interactions. vol 173. issue 1. 2008-07-31. PMID:18367157. |
liver samples were collected for the analysis of proliferating cell nuclear antigen (pcna), transforming growth factor alpha (tgf-alpha), p53, apoptosis and induction of single hepatocytes and minifoci positive for the enzyme glutathione s-transferase p-form (gst-p). |
2008-07-31 |
2023-08-12 |
rat |
| Horng-Cherng Wu, Chuan-Sheng Chiu, Jen-Leih Wu, Hong-Yi Gong, Ming-Chyuan Chen, Ming-Wei Lu, Jiann-Ruey Hon. Zebrafish anti-apoptotic protein zfBcl-xL can block betanodavirus protein alpha-induced mitochondria-mediated secondary necrosis cell death. Fish & shellfish immunology. vol 24. issue 4. 2008-07-30. PMID:18276161. |
betanodavirus protein alpha induces cell apoptosis or secondary necrosis by a poorly understood process. |
2008-07-30 |
2023-08-12 |
zebrafish |
| Horng-Cherng Wu, Chuan-Sheng Chiu, Jen-Leih Wu, Hong-Yi Gong, Ming-Chyuan Chen, Ming-Wei Lu, Jiann-Ruey Hon. Zebrafish anti-apoptotic protein zfBcl-xL can block betanodavirus protein alpha-induced mitochondria-mediated secondary necrosis cell death. Fish & shellfish immunology. vol 24. issue 4. 2008-07-30. PMID:18276161. |
we conclude that rgnnv protein alpha induces apoptosis followed by secondary necrotic cell death through a mitochondria-mediated death pathway and activation of caspases-8 and -3. |
2008-07-30 |
2023-08-12 |
zebrafish |
| L M Prieto, J W Brown, C Perez-Stable, L M Fishma. High dose 17 beta-estradiol and the alpha-estrogen agonist PPT trigger apoptosis in human adrenal carcinoma cells but the beta-estrogen agonist DPN does not. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 40. issue 5. 2008-07-22. PMID:18491249. |
these studies suggest that induction of apoptosis by estrogen in sw-13 human adrenal cortical carcinoma cultures is mediated by the alpha-receptor, but the g2/m blocking effect of estrogen is not likely to be related to either alpha or beta mechanisms. |
2008-07-22 |
2023-08-12 |
human |
| Regine Lüpertz, Yvonni Chovolou, Andreas Kampkötter, Wim Wätjen, Regine Kah. Catalase overexpression impairs TNF-alpha induced NF-kappaB activation and sensitizes MCF-7 cells against TNF-alpha. Journal of cellular biochemistry. vol 103. issue 5. 2008-07-16. PMID:17879952. |
the pleiotropic cytokine tumor necrosis factor alpha (tnf-alpha) can induce apoptosis but also supports cell survival pathways. |
2008-07-16 |
2023-08-12 |
Not clear |