| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oriane E Chausiaux, Margaret H Abel, Fiona O Baxter, Walid T Khaled, Peter J I Ellis, Harry M Charlton, Nabeel A Affar. Hypogonadal mouse, a model to study the effects of the endogenous lack of gonadotropins on apoptosis. Biology of reproduction. vol 78. issue 1. 2008-03-25. PMID:17671269. |
we confirmed our observations of sertoli cell apoptosis using anti-mullerian inhibiting substance staining and staining for cleaved fodrin alpha. |
2008-03-25 |
2023-08-12 |
mouse |
| Xinmin Zheng, Ross J Resnick, David Shallowa. Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi. International journal of cancer. vol 122. issue 9. 2008-03-18. PMID:18183590. |
apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by ptp alpha and src rnai. |
2008-03-18 |
2023-08-12 |
human |
| Xinmin Zheng, Ross J Resnick, David Shallowa. Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi. International journal of cancer. vol 122. issue 9. 2008-03-18. PMID:18183590. |
src and ptp alpha rnai induced apoptosis in estrogen receptor (er)-negative breast cancer and colon cancer cells, but not in immortalized noncancerous breast cells, er-positive breast cancer cells or other cancer cell types tested. |
2008-03-18 |
2023-08-12 |
human |
| Su Youn Nam, Joo Sung Kim, Jung Mogg Kim, Jong Yeul Lee, Nayoung Kim, Hyun Chae Jung, In Sung Son. DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 2. 2008-03-14. PMID:18222973. |
apoptosis was determined by in situ terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labeling assay, and the expression of ki-67, phospho-kappab kinase alpha (ikkalpha), and cox-2 were evaluated by immunohistochemistry. |
2008-03-14 |
2023-08-12 |
mouse |
| Heping Yang, Nathaniel Magilnick, Meng Xia, Shelly C L. Effects of hepatocyte growth factor on glutathione synthesis, growth, and apoptosis is cell density-dependent. Experimental cell research. vol 314. issue 2. 2008-03-05. PMID:17950727. |
hgf acts as a mitogen in h4iie cells under low cell density and protects against tumor necrosis factor alpha (tnfalpha)-induced apoptosis by limiting jnk activation. |
2008-03-05 |
2023-08-12 |
Not clear |
| Ronald S Y Cheung, John T Brooling, Melissa M Johnson, Kimberly J Riehle, Jean S Campbell, Nelson Faust. Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells. Carcinogenesis. vol 28. issue 12. 2008-03-04. PMID:17698969. |
both myc and transforming growth factor alpha (tgfalpha) are commonly over-expressed in hepatocellular carcinomas, and transgenic mice expressing these genes rapidly develop tumors via the suppression of myc-induced apoptosis by the growth factor. |
2008-03-04 |
2023-08-12 |
mouse |
| S Sebens Müerköster, A V Rausch, A Isberner, J Minkenberg, E Blaszczuk, M Witt, U R Fölsch, F Schmitz, H Schäfer, A Arl. The apoptosis-inducing effect of gastrin on colorectal cancer cells relates to an increased IEX-1 expression mediating NF-kappa B inhibition. Oncogene. vol 27. issue 8. 2008-03-03. PMID:17704804. |
moreover, tumor necrosis factor alpha (tnfalpha)- or 5-fu-induced apoptosis that is greatly enhanced by g17 treatment in colo320wt cells was prevented if iex-1 expression was repressed. |
2008-03-03 |
2023-08-12 |
mouse |
| Zafira Castaño, Nuria Vergara-Irigaray, Maria J Pajares, Luis M Montuenga, Ruben Pi. Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells. International journal of cancer. vol 122. issue 7. 2008-02-26. PMID:17973258. |
induction of alpha cp-4 expression caused cell cycle arrest in g(2)/m in 3 out of the 7 lung cancer cell lines studied, while no effect on apoptosis was observed. |
2008-02-26 |
2023-08-12 |
mouse |
| Zafira Castaño, Nuria Vergara-Irigaray, Maria J Pajares, Luis M Montuenga, Ruben Pi. Expression of alpha CP-4 inhibits cell cycle progression and suppresses tumorigenicity of lung cancer cells. International journal of cancer. vol 122. issue 7. 2008-02-26. PMID:17973258. |
immunocytochemistry analysis of the xenograft tumors revealed an in vivo effect of alpha cp-4 on cell proliferation and no effect on apoptosis. |
2008-02-26 |
2023-08-12 |
mouse |
| C M Kemp, R G Bardsley, T Par. Changes in caspase activity during the postmortem conditioning period and its relationship to shear force in porcine longissimus muscle. Journal of animal science. vol 84. issue 10. 2008-02-20. PMID:16971587. |
specific degradation products of alpha ii spectrin and parp, which are known indicators of caspase activity, and apoptosis were detected on immunoblots of muscle samples taken over the postmortem period. |
2008-02-20 |
2023-08-12 |
Not clear |
| Sébastien L'Hoste, Mallorie Poet, Christophe Duranton, Radia Belfodil, Herv é Barriere, Isabelle Rubera, Michel Tauc, Chantal Poujeol, Jacques Barhanin, Phillipe Poujeo. Role of TASK2 in the control of apoptotic volume decrease in proximal kidney cells. The Journal of biological chemistry. vol 282. issue 50. 2008-02-15. PMID:17947235. |
apoptosis was induced by staurosporine, cyclosporin a, or tumor necrosis factor alpha. |
2008-02-15 |
2023-08-12 |
mouse |
| Lili Liu, Xiaoxuan Ning, Li Sun, Hongbo Zhang, Yongquan Shi, Changcun Guo, Shuang Han, Jie Liu, Shiren Sun, Zheyi Han, Kaichun Wu, Daiming Fa. Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer. Cancer science. vol 99. issue 1. 2008-02-15. PMID:17953712. |
annexin-v/propidium iodide staining analysis revealed hypoxia or forced hif-1 alpha expression reduced apoptosis by 24% or 18% in sgc7901 cells (p < 0.05). |
2008-02-15 |
2023-08-12 |
human |
| Lili Liu, Xiaoxuan Ning, Li Sun, Hongbo Zhang, Yongquan Shi, Changcun Guo, Shuang Han, Jie Liu, Shiren Sun, Zheyi Han, Kaichun Wu, Daiming Fa. Hypoxia-inducible factor-1 alpha contributes to hypoxia-induced chemoresistance in gastric cancer. Cancer science. vol 99. issue 1. 2008-02-15. PMID:17953712. |
we further demonstrated that hif-1 alpha overexpression showed a 1.85-fold increased expression of bcl-2 and a 2.16-fold decreased expression of bax, and also showed significantly induced expression of p-gp and mrp1, which indicated that hif-1 alpha may confer hypoxia-induced drug resistance via inhibition of drug-induced apoptosis and decreases in intracellular drug accumulation. |
2008-02-15 |
2023-08-12 |
human |
| So-Young Kim, MiRan Seo, Yeni Kim, Yun-Il Lee, Jung-Min Oh, Eun-Ah Cho, Jae-Seung Kang, Yong-Sung Juhn. Stimulatory heterotrimeric GTP-binding protein inhibits hydrogen peroxide-induced apoptosis by repressing BAK induction in SH-SY5Y human neuroblastoma cells. The Journal of biological chemistry. vol 283. issue 3. 2008-02-14. PMID:17991745. |
thus, in this study we aimed to investigate the role of the alpha subunit of g(s) (galpha(s)) in the ros-induced apoptosis of cancer cells. |
2008-02-14 |
2023-08-12 |
human |
| Luciano Vellon, Javier A Menendez, Hong Liu, Ruth Lup. Up-regulation of alphavbeta3 integrin expression is a novel molecular response to chemotherapy-induced cell damage in a heregulin-dependent manner. Differentiation; research in biological diversity. vol 75. issue 9. 2008-02-08. PMID:17999741. |
alpha(v)beta(3) integrin has a dual role in apoptosis. |
2008-02-08 |
2023-08-12 |
human |
| Luciano Vellon, Javier A Menendez, Hong Liu, Ruth Lup. Up-regulation of alphavbeta3 integrin expression is a novel molecular response to chemotherapy-induced cell damage in a heregulin-dependent manner. Differentiation; research in biological diversity. vol 75. issue 9. 2008-02-08. PMID:17999741. |
whereas ligated alpha(v)beta(3) activates cell survival pathways and suppresses pro-apoptotic signals, unligated alpha(v)beta(3) or integrins bound to soluble ligands promote apoptosis. |
2008-02-08 |
2023-08-12 |
human |
| Luciano Vellon, Javier A Menendez, Hong Liu, Ruth Lup. Up-regulation of alphavbeta3 integrin expression is a novel molecular response to chemotherapy-induced cell damage in a heregulin-dependent manner. Differentiation; research in biological diversity. vol 75. issue 9. 2008-02-08. PMID:17999741. |
this mia-induced increase of alpha(v)beta(3) expression was correlated with a decrease in cell viability and an increase in apoptosis in mda-mb-231/as31 cells, indicating that overexpression of alpha(v)beta(3) is linked to chemotherapy-induced cell death in low hrg-expressing breast cancer models. |
2008-02-08 |
2023-08-12 |
human |
| Timothy C Hallstrom, Seiichi Mori, Joseph R Nevin. An E2F1-dependent gene expression program that determines the balance between proliferation and cell death. Cancer cell. vol 13. issue 1. 2008-02-06. PMID:18167336. |
activation of ampk alpha 2 with an amp analog further stimulates e2f1-induced apoptosis. |
2008-02-06 |
2023-08-12 |
Not clear |
| Pachiyappan Kamarajan, Yvonne L Kapil. An altered fibronectin matrix induces anoikis of human squamous cell carcinoma cells by suppressing integrin alpha v levels and phosphorylation of FAK and ERK. Apoptosis : an international journal on programmed cell death. vol 12. issue 12. 2008-01-30. PMID:17879163. |
overexpression of integrin alpha v or fak inhibited the increase in caspase-3 activation and apoptosis, whereas suppression of alpha v or fak triggered a further significant increase in apoptosis, indicating that the apoptosis was mediated by suppression of integrin alpha v levels and dephosphorylation of fak. |
2008-01-30 |
2023-08-12 |
human |
| Mirjam T Epping, Liming Wang, Jane A Plumb, Michele Lieb, Hinrich Gronemeyer, Robert Brown, René Bernard. A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 45. 2008-01-28. PMID:17968018. |
we report here that ectopic expression of two genes that act on retinoic acid (ra) signaling can cause resistance to growth arrest and apoptosis induced by hdaci of different chemical classes: the retinoic acid receptor alpha (raralpha) and preferentially expressed antigen of melanoma (prame), a repressor of ra signaling. |
2008-01-28 |
2023-08-12 |
mouse |