| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dinender K Singla, Gary E Lyons, Timothy J Kam. Transplanted embryonic stem cells following mouse myocardial infarction inhibit apoptosis and cardiac remodeling. American journal of physiology. Heart and circulatory physiology. vol 293. issue 2. 2007-09-18. PMID:17416601. |
in conclusion, transplanted mouse es cells in the infarcted heart inhibit apoptosis, fibrosis, and hypertrophy, thereby reducing adverse remodeling. |
2007-09-18 |
2023-08-12 |
mouse |
| Takuro Yamashita, Eiichiro Yamamoto, Keiichiro Kataoka, Taishi Nakamura, Shinji Matsuba, Yoshiko Tokutomi, Yi-Fei Dong, Hidenori Ichijo, Hisao Ogawa, Shokei Kim-Mitsuyam. Apoptosis signal-regulating kinase-1 is involved in vascular endothelial and cardiac remodeling caused by nitric oxide deficiency. Hypertension (Dallas, Tex. : 1979). vol 50. issue 3. 2007-09-18. PMID:17646574. |
l-name treatment in wild mice caused cardiac hypertrophy, myocyte apoptosis, macrophage infiltration, coronary arterial remodeling, interstitial fibrosis, and the expression of monocyte chemoattractant protein-1 and transforming growth factor-beta1, whereas these cardiac changes by l-name were absent in ask1-deficient mice. |
2007-09-18 |
2023-08-12 |
mouse |
| Kozo Morita, Takeshi Miyamoto, Nobuyuki Fujita, Yoshiaki Kubota, Keisuke Ito, Keiyo Takubo, Kana Miyamoto, Ken Ninomiya, Toru Suzuki, Ryotaro Iwasaki, Mitsuru Yagi, Hironari Takaishi, Yoshiaki Toyama, Toshio Sud. Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification. The Journal of experimental medicine. vol 204. issue 7. 2007-09-17. PMID:17576777. |
chondrocyte hypertrophy during endochondral ossification is a well-controlled process in which proliferating chondrocytes stop proliferating and differentiate into hypertrophic chondrocytes, which then undergo apoptosis. |
2007-09-17 |
2023-08-12 |
mouse |
| Lin Yan, Dorothy E Vatner, J Patrick O'Connor, Andreas Ivessa, Hui Ge, Wei Chen, Shinichi Hirotani, Yoshihiro Ishikawa, Junichi Sadoshima, Stephen F Vatne. Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell. vol 130. issue 2. 2007-09-13. PMID:17662940. |
old ac5 ko mice are also protected from aging-induced cardiomyopathy, e.g., hypertrophy, apoptosis, fibrosis, and reduced cardiac function. |
2007-09-13 |
2023-08-12 |
mouse |
| Peter A Watson, Jane E B Reusch, Sylvia A McCune, Leslie A Leinwand, Stephen W Luckey, John P Konhilas, David A Brown, Adam J Chicco, Genevieve C Sparagna, Carlin S Long, Russell L Moor. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17337597. |
potential regulation of two factors linked to physiological outcomes with left ventricular (lv) hypertrophy, resistance to apoptosis, and matching of metabolic capacity, by the transcription factor cyclic-nucleotide regulatory element binding protein (creb), was examined in the two models of physiological lv hypertrophy: involuntary treadmill running of female sprague-dawley rats and voluntary exercise wheel running in female c57bl/6 mice. |
2007-09-12 |
2023-08-12 |
mouse |
| Peter A Watson, Jane E B Reusch, Sylvia A McCune, Leslie A Leinwand, Stephen W Luckey, John P Konhilas, David A Brown, Adam J Chicco, Genevieve C Sparagna, Carlin S Long, Russell L Moor. Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise. American journal of physiology. Heart and circulatory physiology. vol 293. issue 1. 2007-09-12. PMID:17337597. |
these data support a model wherein creb contributes to physiological hypertrophy by enhancing expression of genes important for efficient oxidative capacity and resistance to apoptosis. |
2007-09-12 |
2023-08-12 |
mouse |
| b' T Pelik\\xc3\\xa1nov\\xc3\\xa. [Pathogenesis of diabetic retinopathy]. Vnitrni lekarstvi. vol 53. issue 5. 2007-08-30. PMID:17642432.' |
these activated cells change the production pattern of a number of mediators such as growth factors, vasoactive agents, coagulation factors and adhesion molecules resulting in increased blood flow, increased capillary permeability, proliferation of extracellular matrix and thickening of basal membranes, altered cell turnover (apoptosis, proliferation, hypertrophy), procoagulant and proaggregant patterns, and finally in angiogenesis and tissue remodelling. |
2007-08-30 |
2023-08-12 |
Not clear |
| Tetyana L Vasylyeva, Robert J Ferr. Novel roles of the IGF-IGFBP axis in etiopathophysiology of diabetic nephropathy. Diabetes research and clinical practice. vol 76. issue 2. 2007-08-20. PMID:17011663. |
high ambient glucose level transforms intracellular pathways, promoting stable phenotypic changes in the glomerulus such as mesangial cell hypertrophy, podocyte apoptosis, and matrix expansion. |
2007-08-20 |
2023-08-12 |
Not clear |
| Angela Clerk, Timothy E Cullingford, Stephen J Fuller, Alejandro Giraldo, Thomais Markou, Sampsa Pikkarainen, Peter H Sugde. Signaling pathways mediating cardiac myocyte gene expression in physiological and stress responses. Journal of cellular physiology. vol 212. issue 2. 2007-08-16. PMID:17450511. |
in response to pathophysiological stresses, cardiac myocytes undergo hypertrophic growth or apoptosis, responses associated with the development of cardiac pathologies. |
2007-08-16 |
2023-08-12 |
Not clear |
| Rei Shibata, Yasuhiro Izumiya, Kaori Sato, Kyriakos Papanicolaou, Shinji Kihara, Wilson S Colucci, Flora Sam, Noriyuki Ouchi, Kenneth Wals. Adiponectin protects against the development of systolic dysfunction following myocardial infarction. Journal of molecular and cellular cardiology. vol 42. issue 6. 2007-08-15. PMID:17499764. |
administration of adenovirus-mediated adiponectin in wt mice resulted in decreased lv dilatation and improved lv function that was associated with increased capillary density in the infarct border zone and decreased myocyte hypertrophy, diminished myocardial apoptosis and decreased interstitial fibrosis in the remote zone. |
2007-08-15 |
2023-08-12 |
mouse |
| Kirsten Leineweber, Gerd Heusch, Rainer Schul. Regulation and role of the presynaptic and myocardial Na+/H+ exchanger NHE1: effects on the sympathetic nervous system in heart failure. Cardiovascular drug reviews. vol 25. issue 2. 2007-08-09. PMID:17614935. |
during acute ischemia/reperfusion and in heart failure the activity/amount of nhe1 is increased, leading to intracellular ca(2+) overload and promoting structural (apoptosis, hypertrophy) and functional (arrhythmias, hypercontraction) myocardial damage. |
2007-08-09 |
2023-08-12 |
Not clear |
| Sandra Levrand, Pal Pacher, Benoît Pesse, Joelle Rolli, François Feihl, Bernard Waeber, Lucas Liaude. Homocysteine induces cell death in H9C2 cardiomyocytes through the generation of peroxynitrite. Biochemical and biophysical research communications. vol 359. issue 3. 2007-08-07. PMID:17544363. |
in additional experiments performed in primary rat ventricular cardiomyocytes, hcy (1 mm, 6h) activated the phosphorylation of the map kinases erk and jnk, two essential stress signaling kinases regulating myocardial apoptosis, hypertrophy and remodeling. |
2007-08-07 |
2023-08-12 |
rat |
| A Jiménez, M A López-González, F Solano, A Chadli, F Delgado, E Pintado, M Luca. Hypomethylation of DNA and resistance to apoptosis in tonsillar hypertrophy in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. vol 17. issue 3. 2007-08-06. PMID:16672010. |
hypomethylation of dna and resistance to apoptosis in tonsillar hypertrophy in children. |
2007-08-06 |
2023-08-12 |
Not clear |
| A Jiménez, M A López-González, F Solano, A Chadli, F Delgado, E Pintado, M Luca. Hypomethylation of DNA and resistance to apoptosis in tonsillar hypertrophy in children. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. vol 17. issue 3. 2007-08-06. PMID:16672010. |
we analyzed the hypomethylation of dna and the sensitivity to apoptosis of tonsillar cells and peripheral blood lymphocytes (pbl) in twenty children with either recurrent tonsillitis (rt) or tonsillar hypertrophy (th). |
2007-08-06 |
2023-08-12 |
Not clear |
| Elena V Tchetina, Masahiko Kobayashi, Tadashi Yasuda, Tineke Meijers, Isabelle Pidoux, A Robin Pool. Chondrocyte hypertrophy can be induced by a cryptic sequence of type II collagen and is accompanied by the induction of MMP-13 and collagenase activity: implications for development and arthritis. Matrix biology : journal of the International Society for Matrix Biology. vol 26. issue 4. 2007-07-18. PMID:17306969. |
immunostaining for anti-ki67, anti-pcna, (proliferation markers), type x collagen, cleavage of type ii collagen by collagenases (hypertrophy markers) and tunel staining (hypertrophy and apoptosis markers) were used to detect progressive maturational stages of chondrocyte hypertrophy. |
2007-07-18 |
2023-08-12 |
cattle |
| Hiroyuki Tsutsui, Shouji Matsushima, Shintaro Kinugawa, Tomomi Ide, Naoki Inoue, Yukihiro Ohta, Takashi Yokota, Sanae Hamaguchi, Kenji Sunagaw. Angiotensin II type 1 receptor blocker attenuates myocardial remodeling and preserves diastolic function in diabetic heart. Hypertension research : official journal of the Japanese Society of Hypertension. vol 30. issue 5. 2007-07-18. PMID:17587756. |
improvement of lv diastolic function was accompanied by the attenuation of myocyte hypertrophy, interstitial fibrosis and apoptosis in association with the expression of connective tissue growth factor (ctgf) and myocardial oxidative stress. |
2007-07-18 |
2023-08-12 |
mouse |
| Heinz-Juergen Hausser, Markus A Ruegg, Rolf E Brenner, Iwona Ksiaze. Agrin is highly expressed by chondrocytes and is required for normal growth. Histochemistry and cell biology. vol 127. issue 4. 2007-07-16. PMID:17186266. |
compression of this zone was not caused by reduced viability of hypertrophic chondrocytes, as no differences in the apoptosis rates could be observed. |
2007-07-16 |
2023-08-12 |
mouse |
| Yasuo Terauch. [PPARgamma and metabolic syndrome]. Rinsho byori. The Japanese journal of clinical pathology. vol 55. issue 5. 2007-07-13. PMID:17593690. |
by contrast, potent activation of ppary by thiazolidinedione (tzd) stimulated adipocyte differentiation and apoptosis, thereby preventing adipocyte hypertrophy, which is associated with the alleviation of insulin resistance, presumably due to decreases in ffa, and tnfa, and the up-regulation of adiponectin. |
2007-07-13 |
2023-08-12 |
mouse |
| Caroline B Marshall, Stuart J Shanklan. Cell cycle regulatory proteins in podocyte health and disease. Nephron. Experimental nephrology. vol 106. issue 2. 2007-07-10. PMID:17570940. |
in response to injury, podocytes may undergo several cell fates, including proliferation, de-differentiation, hypertrophy, apoptosis, or necrosis. |
2007-07-10 |
2023-08-12 |
mouse |
| Ya Yang, Eryuan Lia. Mutant WISP3 triggers the phenotype shift of articular chondrocytes by promoting sensitivity to IGF-1 hypothesis of spondyloepiphyseal dysplasia tarda with progressive arthropathy (SEDT-PA). Medical hypotheses. vol 68. issue 6. 2007-07-03. PMID:17363178. |
so, the articular chondrocytes undergo hypertrophic and terminal differentiation apoptosis. |
2007-07-03 |
2023-08-12 |
Not clear |