| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Harold Bays, Lawrence Blonde, Robert Rosenso. Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients? Expert review of cardiovascular therapy. vol 4. issue 6. 2007-01-30. PMID:17173503. |
peroxisome proliferator-activated receptor-gamma agonists increase the recruitment, proliferation and differentiation of preadipocytes ('healthy fat') and cause apoptosis of hypertrophic and dysfunctional (including visceral) adipocytes resulting in improved fat function and improved metabolic parameters associated with efrmd. |
2007-01-30 |
2023-08-12 |
Not clear |
| Shouji Matsushima, Shintaro Kinugawa, Tomomi Ide, Hidenori Matsusaka, Naoki Inoue, Yukihiro Ohta, Takashi Yokota, Kenji Sunagawa, Hiroyuki Tsutsu. Overexpression of glutathione peroxidase attenuates myocardial remodeling and preserves diastolic function in diabetic heart. American journal of physiology. Heart and circulatory physiology. vol 291. issue 5. 2007-01-12. PMID:16844917. |
improvement of lv diastolic function was accompanied by the attenuation of myocyte hypertrophy, interstitial fibrosis, and apoptosis. |
2007-01-12 |
2023-08-12 |
mouse |
| Gentzon Hall, Jeffery D Hasday, Terry B Roger. Regulating the regulator: NF-kappaB signaling in heart. Journal of molecular and cellular cardiology. vol 41. issue 4. 2007-01-12. PMID:16949095. |
the nuclear factor-kappab (nf-kappab) signaling pathway has been linked to several pathologic processes in the myocardium including cardiomyocyte proinflammatory cytokine release, ischemia/reperfusion injury, hypertrophy and apoptosis. |
2007-01-12 |
2023-08-12 |
Not clear |
| Nicolaas de Jonge, Marie Jose Goumans, Daan Lips, Rutger Hassink, Eva J Vlug, Roy van der Meel, Christopher Donald Emmerson, Joppe Nijman, Leon de Windt, Pieter A Doevendan. Controlling cardiomyocyte survival. Novartis Foundation symposium. vol 274. 2007-01-12. PMID:17019805. |
gradually the distinction between signalling pathways originally believed to be specific for either hypertrophy, cell cycle control, apoptosis and cell survival are fading. |
2007-01-12 |
2023-08-12 |
mouse |
| Nicolaas de Jonge, Marie Jose Goumans, Daan Lips, Rutger Hassink, Eva J Vlug, Roy van der Meel, Christopher Donald Emmerson, Joppe Nijman, Leon de Windt, Pieter A Doevendan. Controlling cardiomyocyte survival. Novartis Foundation symposium. vol 274. 2007-01-12. PMID:17019805. |
whether hypertrophy following ischaemia is adaptive or maladaptive and whether all apoptosis is detrimental will have to be determined by assessment of left ventricular function through invasive and noninvasive methods. |
2007-01-12 |
2023-08-12 |
mouse |
| Kazuhiko Nishida, Kinya Ots. The role of apoptosis signal-regulating kinase 1 in cardiomyocyte apoptosis. Antioxidants & redox signaling. vol 8. issue 9-10. 2007-01-04. PMID:16987025. |
in cardiomyocytes, ask1 is involved not only in cardiac apoptosis, leading to cardiac remodeling, but also in cardiac hypertrophy as well as nonapoptotic cardiomyocyte death. |
2007-01-04 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsui, Tomomi Ide, Shintaro Kinugaw. Mitochondrial oxidative stress, DNA damage, and heart failure. Antioxidants & redox signaling. vol 8. issue 9-10. 2007-01-04. PMID:16987026. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2007-01-04 |
2023-08-12 |
Not clear |
| Claudia Penna, Raffaella Rastaldo, Daniele Mancardi, Sandra Cappello, Pasquale Pagliaro, Nico Westerhof, Gianni Losan. Effect of endothelins on the cardiovascular system. Journal of cardiovascular medicine (Hagerstown, Md.). vol 7. issue 9. 2006-12-19. PMID:16932076. |
the chronic effect of ets on the myocardium results in hypertrophy and prevention of apoptosis, two processes that are together responsible for the contradictory effect of ets in heart failure. |
2006-12-19 |
2023-08-12 |
Not clear |
| Maria A Mello, Rocky S Tua. Effects of TGF-beta1 and triiodothyronine on cartilage maturation: in vitro analysis using long-term high-density micromass cultures of chick embryonic limb mesenchymal cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 24. issue 11. 2006-12-07. PMID:16955422. |
using in vitro, long-term, high-density, micromass cultures of chick embryonic mesenchyme, that recapitulate the process of chondrogenesis, chondrocyte maturation, and hypertrophy, we have investigated the importance of a balance between proliferation and apoptosis in cartilage maturation, focusing specifically on the effects of transforming growth factor-beta1 (tgf-beta1) and the thyroid hormone, triiodothyronine (t3). |
2006-12-07 |
2023-08-12 |
chicken |
| Maria A Mello, Rocky S Tua. Effects of TGF-beta1 and triiodothyronine on cartilage maturation: in vitro analysis using long-term high-density micromass cultures of chick embryonic limb mesenchymal cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 24. issue 11. 2006-12-07. PMID:16955422. |
the results support the roles of t3 and tgf-beta in cartilage maturation, i.e., tgf-beta stimulates proliferation and suppresses hypertrophy, while t3 stimulates hypertrophy and apoptosis. |
2006-12-07 |
2023-08-12 |
chicken |
| Ivana Fantozzi, Oleksandr Platoshyn, Ada H Wong, Shen Zhang, Carmelle V Remillard, Manohar R Furtado, Olga V Petrauskene, Jason X-J Yua. Bone morphogenetic protein-2 upregulates expression and function of voltage-gated K+ channels in human pulmonary artery smooth muscle cells. American journal of physiology. Lung cellular and molecular physiology. vol 291. issue 5. 2006-11-29. PMID:16815889. |
bone morphogenetic proteins (bmps) inhibit proliferation and induce apoptosis in normal human pasmc, whereas dysfunctional bmp signaling and downregulated k(v) channels are involved in pulmonary vascular medial hypertrophy associated with pulmonary hypertension. |
2006-11-29 |
2023-08-12 |
human |
| Laimute Taraseviciene-Stewart, Robertas Scerbavicius, Kang-Hyeon Choe, Carlyne Cool, Kathy Wood, Rubin M Tuder, Nana Burns, Michael Kasper, Norbert F Voelke. Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology. vol 291. issue 4. 2006-11-07. PMID:16698853. |
in contrast, treatment of rats with established sph with simvastatin markedly reduced mean pap and right ventricular hypertrophy, and this reduction was associated with caspase-3 activation and pulmonary microvascular endothelial cell apoptosis. |
2006-11-07 |
2023-08-12 |
human |
| Soo Bong Choi, Jin Sun Jang, Sang Mee Hong, Dong Wha Jun, Sunmin Par. Exercise and dexamethasone oppositely modulate beta-cell function and survival via independent pathways in 90% pancreatectomized rats. The Journal of endocrinology. vol 190. issue 2. 2006-11-07. PMID:16899580. |
by contrast, dex expanded beta-cell mass via hypertrophy and neogenesis from precursor cells, rather than increasing proliferation and decreasing apoptosis. |
2006-11-07 |
2023-08-12 |
rat |
| Egbert Bisping, Sadakatsu Ikeda, Sek Won Kong, Oleg Tarnavski, Natalya Bodyak, Julie R McMullen, Satish Rajagopal, Jennifer K Son, Qing Ma, Zhangli Springer, Peter M Kang, Seigo Izumo, William T P. Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure. Proceedings of the National Academy of Sciences of the United States of America. vol 103. issue 39. 2006-10-30. PMID:16983087. |
after transverse aortic constriction (tac), g4d mice developed overt heart failure and eccentric cardiac hypertrophy, associated with significantly increased fibrosis and cardiomyocyte apoptosis. |
2006-10-30 |
2023-08-12 |
mouse |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
heme oxygenase-1 gene transfer inhibits angiotensin ii-mediated rat cardiac myocyte apoptosis but not hypertrophy. |
2006-10-20 |
2023-08-12 |
rat |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
cardiac myocyte apoptosis underlies the pathophysiology of cardiomyopathy, and plays a critical role in the transition from myocardial hypertrophy to heart failure. |
2006-10-20 |
2023-08-12 |
rat |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
angiotensin ii (ang ii) induces cardiac myocyte apoptosis and hypertrophy which contribute to heart failure possibly through enhanced oxidative stress; however, the mechanisms underlying the activation of both pathways and their interactions remain unclear. |
2006-10-20 |
2023-08-12 |
rat |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
in the present study, we have investigated whether overexpression of the antioxidant protein heme oxygenase-1 (ho-1) protects against apoptosis and hypertrophy in cultured rat cardiac myocytes treated with ang ii. |
2006-10-20 |
2023-08-12 |
rat |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
our findings demonstrate that ang ii (100 nm, 24 h) alone upregulates ho-1 expression and induces both myocyte hypertrophy and apoptosis, assessed by measuring terminal deoxynucleotidyltransferase dutp nick-end labelling (tunel) staining, caspase-3 activity and mitochondrial membrane potential. |
2006-10-20 |
2023-08-12 |
rat |
| Roger S Y Foo, Richard C M Siow, Morris J Brown, Martin R Bennet. Heme oxygenase-1 gene transfer inhibits angiotensin II-mediated rat cardiac myocyte apoptosis but not hypertrophy. Journal of cellular physiology. vol 209. issue 1. 2006-10-20. PMID:16826603. |
ang ii elicited apoptosis was augmented in the presence of tin protoporphyrin, an inhibitor of ho activity, while ho-1 gene transfer to myocytes attenuated ang ii-mediated apoptosis but not hypertrophy. |
2006-10-20 |
2023-08-12 |
rat |