| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nuria Olea-Herrero, María Isabel Arenas, Carmen Muñóz-Moreno, Rafael Moreno-Gómez-Toledano, Marta González-Santander, Ignacio Arribas, Ricardo J Bosc. Bisphenol-A induces podocytopathy with proteinuria in mice. Journal of cellular physiology. vol 229. issue 12. 2014-10-20. PMID:24809654. |
on cultured podocytes we first observed that bisphenol-a-at low or high concentrations-(10 nm and 100 nm, respectively) was able to induce hypertrophy, diminish viability, and promote apoptosis. |
2014-10-20 |
2023-08-13 |
mouse |
| Dorota Przybylska, Grazyna Mosienia. [The role of NADPH oxidase NOX4 in regulation of proliferation, senescence and differentiation of the cells]. Postepy biochemii. vol 60. issue 1. 2014-10-20. PMID:25033544. |
it was shown that nox4 has an impact on vasoconstriction, atherosclerosis development, vascular cells hypertrophy, apoptosis and differentiation. |
2014-10-20 |
2023-08-13 |
human |
| Shuguang Dong, Wenhan Ma, Bohan Hao, Fen Hu, Lianhua Yan, Xiaofei Yan, Ya Wang, Zhijian Chen, Zhaohui Wan. microRNA-21 promotes cardiac fibrosis and development of heart failure with preserved left ventricular ejection fraction by up-regulating Bcl-2. International journal of clinical and experimental pathology. vol 7. issue 2. 2014-10-14. PMID:24551276. |
it was demonstrated that, in systolic heart failure, microrna-21 (mir-21) could inhibit the apoptosis of cardiac fibroblasts, leading to cardiac hypertrophy and myocardial fibrosis, but the role of mir-21 in hfpef remains unknown. |
2014-10-14 |
2023-08-12 |
rat |
| Jun Ho Lee, Jeen-Woo Par. Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes. Biochimie. vol 99. 2014-10-10. PMID:24296260. |
attenuated mitochondrial nadp+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of h9c2 cardiomyocytes. |
2014-10-10 |
2023-08-12 |
Not clear |
| Jun Ho Lee, Jeen-Woo Par. Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes. Biochimie. vol 99. 2014-10-10. PMID:24296260. |
here, we showed that transfection of h9c2 clonal myoblastic cells with small interfering rna (sirna) specific for idpm markedly attenuated idpm expression and substantially induced apoptosis, senescence, and hypertrophy as indicated by increased atrial natriuretic peptide (anp) gene expression, a marker of cardiomyocyte hypertrophy, and a larger cell size. |
2014-10-10 |
2023-08-12 |
Not clear |
| Jun Ho Lee, Jeen-Woo Par. Attenuated mitochondrial NADP+-dependent isocitrate dehydrogenase activity induces apoptosis and hypertrophy of H9c2 cardiomyocytes. Biochimie. vol 99. 2014-10-10. PMID:24296260. |
taken together, our results suggest that the suppression of idpm expression by sirna induces apoptosis and hypertrophy of cultured cardiomyocytes through the disruption of cellular redox balance. |
2014-10-10 |
2023-08-12 |
Not clear |
| Julie Chao, Grant Bledsoe, Lee Cha. Tissue kallikrein-kinin therapy in hypertension and organ damage. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques. vol 69. 2014-09-30. PMID:25130039. |
tissue kallikrein/kinin treatment attenuates cardiovascular, renal, and brain injury by inhibiting oxidative stress, apoptosis, inflammation, hypertrophy, and fibrosis and promoting angiogenesis and neurogenesis. |
2014-09-30 |
2023-08-13 |
Not clear |
| Guoyan Liang, Chengjie Lian, Di Huang, Wenjie Gao, Anjing Liang, Yan Peng, Wei Ye, Zizhao Wu, Peiqiang Su, Dongsheng Huan. Endoplasmic reticulum stress-unfolding protein response-apoptosis cascade causes chondrodysplasia in a col2a1 p.Gly1170Ser mutated mouse model. PloS one. vol 9. issue 1. 2014-09-29. PMID:24475193. |
apoptosis occurred prior to hypertrophy, prevented the formation of a hypertrophic zone, disrupted normal chondrogenic signaling pathways, and eventually caused chondrodysplasia. |
2014-09-29 |
2023-08-12 |
mouse |
| Takumi Toya, Daihiko Hakuno, Yasunaga Shiraishi, Takehiko Kujiraoka, Takeshi Adach. Arginase inhibition augments nitric oxide production and facilitates left ventricular systolic function in doxorubicin-induced cardiomyopathy in mice. Physiological reports. vol 2. issue 9. 2014-09-29. PMID:25263201. |
echocardiography revealed that administration of a potent, reversible arginase inhibitor n-omega-hydroxy-nor-l-arginine completely reversed doxorubicin-induced decrease in the ejection fraction, in parallel with expression levels of bnp mrna, without affecting apoptosis, hypertrophy, fibrosis, or macrophage infiltration in the left ventricle. |
2014-09-29 |
2023-08-13 |
mouse |
| Bing Feng, Xiao-Bo Zhou, Xu Yang, Zi-Ling Ye, Zuo-Yun H. [Apoptosis of hypertrophic cardiomyocytes stimulated by hypoxia-reoxygenation is partially mediated by apoptosis-inducing factor]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 6. 2014-09-26. PMID:17173196. |
[apoptosis of hypertrophic cardiomyocytes stimulated by hypoxia-reoxygenation is partially mediated by apoptosis-inducing factor]. |
2014-09-26 |
2023-08-12 |
Not clear |
| Bing Feng, Xiao-Bo Zhou, Xu Yang, Zi-Ling Ye, Zuo-Yun H. [Apoptosis of hypertrophic cardiomyocytes stimulated by hypoxia-reoxygenation is partially mediated by apoptosis-inducing factor]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 6. 2014-09-26. PMID:17173196. |
cardiomyocyte apoptosis leads to the functional incapacitation of myocardial plasmodium and plays an important role in the pathogenesis of heart failure transformed from compensable cardiac hypertrophy. |
2014-09-26 |
2023-08-12 |
Not clear |
| Bing Feng, Xiao-Bo Zhou, Xu Yang, Zi-Ling Ye, Zuo-Yun H. [Apoptosis of hypertrophic cardiomyocytes stimulated by hypoxia-reoxygenation is partially mediated by apoptosis-inducing factor]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 6. 2014-09-26. PMID:17173196. |
the sirna transfection also reduced the apoptosis of hypertrophic cardiomyocytes in the groups of h8h/r and h12h/r but not in the groups of h8h and h12h. |
2014-09-26 |
2023-08-12 |
Not clear |
| Bing Feng, Xiao-Bo Zhou, Xu Yang, Zi-Ling Ye, Zuo-Yun H. [Apoptosis of hypertrophic cardiomyocytes stimulated by hypoxia-reoxygenation is partially mediated by apoptosis-inducing factor]. Sheng li xue bao : [Acta physiologica Sinica]. vol 58. issue 6. 2014-09-26. PMID:17173196. |
these data suggest that aif plays a pivotal role in the apoptosis of hypertrophic cardiomyocytes induced by hypoxia-reperfusion. |
2014-09-26 |
2023-08-12 |
Not clear |
| Chuanyu Wei, Li Li, Sudhiranjan Gupt. NF-κB-mediated miR-30b regulation in cardiomyocytes cell death by targeting Bcl-2. Molecular and cellular biochemistry. vol 387. issue 1-2. 2014-09-26. PMID:24178239. |
angiotensin ii(ang ii)-stimulated cardiomyocytes hypertrophy and apoptosis are associated with nuclear factor-κb (nf-κb) activation. |
2014-09-26 |
2023-08-12 |
Not clear |
| Lindsay A Bashur, Dongxing Chen, Zhijun Chen, Bojian Liang, Ruggero Pardi, Shunichi Murakami, Guang Zho. Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice. Journal of cellular physiology. vol 229. issue 11. 2014-09-25. PMID:24604556. |
by e18.5, jab1 cko mutant mice exhibited significantly shorter limbs with: very few hypertrophic chondrocytes, disorganized chondrocyte columns, much smaller primary ossification centers, and significantly increased apoptosis. |
2014-09-25 |
2023-08-12 |
mouse |
| Cherng-Shyang Chang, Pei-Jane Tsai, Junne-Ming Sung, Ju-Yi Chen, Li-Chun Ho, Kumar Pandya, Nobuyo Maeda, Yau-Sheng Tsa. Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice. The American journal of pathology. vol 184. issue 2. 2014-09-18. PMID:24287404. |
cotreatment with the diuretic furosemide in wild-type mice attenuated rosiglitazone-induced ch, hypertrophic gene reprogramming, cardiomyocyte apoptosis, hypertrophy-related signal activation, and left ventricular dysfunction. |
2014-09-18 |
2023-08-12 |
mouse |
| Jing Lu, Bo Sun, Rong Huo, Yu-Chun Wang, Di Yang, Yue Xing, Xiao-Lin Xiao, Xin Xie, De-Li Don. Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24648278. |
bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. |
2014-09-05 |
2023-08-12 |
mouse |
| Jing Lu, Bo Sun, Rong Huo, Yu-Chun Wang, Di Yang, Yue Xing, Xiao-Lin Xiao, Xin Xie, De-Li Don. Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24648278. |
our previous work showed that the expression of bone morphogenetic protein-4 (bmp4) was up-regulated in pathological cardiac hypertrophy models and bmp4 induced cardiomyocyte hypertrophy and apoptosis. |
2014-09-05 |
2023-08-12 |
mouse |
| Jing Lu, Bo Sun, Rong Huo, Yu-Chun Wang, Di Yang, Yue Xing, Xiao-Lin Xiao, Xin Xie, De-Li Don. Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24648278. |
bone morphogenetic protein-2 (bmp2) and bmp4 share greater than 80% amino acid homology and there exists an interaction between bmp2 and bmp4, so the aim of the present study was to elucidate the changes of bmp2 in the cardiac hypertrophy models and the effects of bmp2 on bmp4-induced cardiomyocyte hypertrophy and apoptosis. |
2014-09-05 |
2023-08-12 |
mouse |
| Jing Lu, Bo Sun, Rong Huo, Yu-Chun Wang, Di Yang, Yue Xing, Xiao-Lin Xiao, Xin Xie, De-Li Don. Bone morphogenetic protein-2 antagonizes bone morphogenetic protein-4 induced cardiomyocyte hypertrophy and apoptosis. Journal of cellular physiology. vol 229. issue 10. 2014-09-05. PMID:24648278. |
bmp2 itself did not elicit cardiomyocyte hypertrophy and apoptosis, but antagonized bmp4-induced cardiomyocyte hypertrophy and apoptosis. |
2014-09-05 |
2023-08-12 |
mouse |