| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ding-Sheng Jiang, Yu Liu, Heng Zhou, Yan Zhang, Xiao-Dong Zhang, Xiao-Fei Zhang, Ke Chen, Lu Gao, Juan Peng, Hui Gong, Yingjie Chen, Qinglin Yang, Peter P Liu, Guo-Chang Fan, Yunzeng Zou, Hongliang L. Interferon regulatory factor 7 functions as a novel negative regulator of pathological cardiac hypertrophy. Hypertension (Dallas, Tex. : 1979). vol 63. issue 4. 2014-06-02. PMID:24396025. |
cardiac hypertrophy is a complex pathological process that involves multiple factors including inflammation and apoptosis. |
2014-06-02 |
2023-08-12 |
mouse |
| Rodney Rouse, Lin Xu, Sharron Stewart, Jun Zhan. High fat diet and GLP-1 drugs induce pancreatic injury in mice. Toxicology and applied pharmacology. vol 276. issue 2. 2014-05-30. PMID:24534256. |
exocrine pancreatic changes identified in this study included acinar cell injury (hypertrophy, autophagy, apoptosis, necrosis, and atrophy), vascular injury, interstitial edema and inflammation, fat necrosis, and duct changes. |
2014-05-30 |
2023-08-12 |
mouse |
| Eric D Zhu, Leeann Louis, Daniel J Brooks, Mary L Bouxsein, Marie B Dema. Effect of bisphosphonates on the rapidly growing male murine skeleton. Endocrinology. vol 155. issue 4. 2014-05-19. PMID:24422540. |
this was not associated with altered hypertrophic chondrocyte apoptosis or vascular invasion at the growth plate. |
2014-05-19 |
2023-08-12 |
mouse |
| Jia Tan, Jin-feng F. [Effects of pressure therapy on the proliferation and apoptosis of cells in hypertrophic scar of burn patients]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 29. issue 6. 2014-05-15. PMID:24495636. |
[effects of pressure therapy on the proliferation and apoptosis of cells in hypertrophic scar of burn patients]. |
2014-05-15 |
2023-08-12 |
Not clear |
| Jia Tan, Jin-feng F. [Effects of pressure therapy on the proliferation and apoptosis of cells in hypertrophic scar of burn patients]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns. vol 29. issue 6. 2014-05-15. PMID:24495636. |
to explore the effects of pressure therapy on proliferation and apoptosis of cells in hypertrophic scar (hs) of burn patients. |
2014-05-15 |
2023-08-12 |
Not clear |
| Bao-Heng Liu, Liang Chen, Shi-Rong Li, Zhen-Xiang Wang, Wen-Guang Chen. Smac/DIABLO regulates the apoptosis of hypertrophic scar fibroblasts. International journal of molecular medicine. vol 32. issue 3. 2014-05-12. PMID:23857156. |
smac/diablo regulates the apoptosis of hypertrophic scar fibroblasts. |
2014-05-12 |
2023-08-12 |
human |
| M Elizabeth Sobhia, Baljinder K Grewal, Stanly Paul Ml, Jigneshkumar Patel, Amandeep Kaur, Thongtinlal Haokip, Alekhya Kokkul. Protein kinase C inhibitors: a patent review (2008 - 2009). Expert opinion on therapeutic patents. vol 23. issue 10. 2014-04-28. PMID:23795914. |
the protein kinase c (pkc) is a family of multifunctional isoenzymes involved in apoptosis, migration, adhesion, tumorgenesis, cardiac hypertrophy, angiogenesis, platelet function and inflammation. |
2014-04-28 |
2023-08-12 |
Not clear |
| Sailay Siddiqi, Mark A Sussma. Cell and gene therapy for severe heart failure patients: the time and place for Pim-1 kinase. Expert review of cardiovascular therapy. vol 11. issue 8. 2014-04-28. PMID:23984924. |
this review focuses upon potential for pim-1 kinase to mitigate chronic heart failure by improving myocyte quality through preservation of mitochondrial integrity, prevention of hypertrophy and inhibition of apoptosis. |
2014-04-28 |
2023-08-12 |
Not clear |
| Wei Deng, Duan Jiang, Yi Fang, Heng Zhou, Zhihong Cheng, Yafen Lin, Rui Zhang, Jieyu Zhang, Peng Pu, Yuan Liu, Zhouyan Bian, Qizhu Tan. Hesperetin protects against cardiac remodelling induced by pressure overload in mice. Journal of molecular histology. vol 44. issue 5. 2014-04-21. PMID:23719775. |
cardiac remodelling is a major determinant of heart failure (hf) and is characterised by cardiac hypertrophy, fibrosis, oxidative stress and myocytes apoptosis. |
2014-04-21 |
2023-08-12 |
mouse |
| Wei Deng, Duan Jiang, Yi Fang, Heng Zhou, Zhihong Cheng, Yafen Lin, Rui Zhang, Jieyu Zhang, Peng Pu, Yuan Liu, Zhouyan Bian, Qizhu Tan. Hesperetin protects against cardiac remodelling induced by pressure overload in mice. Journal of molecular histology. vol 44. issue 5. 2014-04-21. PMID:23719775. |
in conclusion, we found that the orange flavonoid hesperetin protected against cardiac remodelling induced by pressure overload via inhibiting cardiac hypertrophy, fibrosis, oxidative stress and myocytes apoptosis. |
2014-04-21 |
2023-08-12 |
mouse |
| Mariana Romero, Carolina Caniffi, Gonzalo Bouchet, Rosana Elesgaray, Myriam Mac Laughlin, Analía Tomat, Cristina Arranz, Maria A Cost. Sex differences in the beneficial cardiac effects of chronic treatment with atrial natriuretic Peptide in spontaneously hypertensive rats. PloS one. vol 8. issue 8. 2014-04-15. PMID:23951276. |
the aim of this study was to investigate both the effects of chronic treatment with atrial natriuretic peptide (anp) on systolic blood pressure (sbp), cardiac nitric oxide (no) system, oxidative stress, hypertrophy, fibrosis and apoptosis in spontaneously hypertensive rats (shr), and sex-related differences in the response to the treatment. |
2014-04-15 |
2023-08-12 |
rat |
| Zhongbing Lu, Xin Xu, John Fassett, Dongmin Kwak, Xiaoyu Liu, Xinli Hu, Huan Wang, Haipeng Guo, Dachun Xu, Shuo Yan, Edward O McFalls, Fei Lu, Robert J Bache, Yingjie Che. Loss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy. Hypertension (Dallas, Tex. : 1979). vol 63. issue 1. 2014-04-11. PMID:24166753. |
under basal conditions, gcn2 knockout mice had normal left ventricular structure and function, but after transverse aortic constriction, they demonstrated less contractile dysfunction, less increase in lung weight, less increase in lung inflammation and vascular remodeling, and less myocardial apoptosis and fibrosis compared with wild-type mice, despite an equivalent degree of left ventricular hypertrophy. |
2014-04-11 |
2023-08-12 |
mouse |
| Jianli Niu, M G F Gilliland, Zhuqing Jin, Pappachan E Kolattukudy, William H Hoffma. MCP-1and IL-1β expression in the myocardia of two young patients with Type 1 diabetes mellitus and fatal diabetic ketoacidosis. Experimental and molecular pathology. vol 96. issue 1. 2014-04-10. PMID:24246157. |
in addition, markers of oxidative stress, apoptosis, collagen deposition and cardiomyocyte hypertrophy were studied. |
2014-04-10 |
2023-08-12 |
Not clear |
| Rishi K Somvanshi, Xiaofan Qiu, Ujendra Kuma. Isoproterenol induced hypertrophy and associated signaling pathways are modulated by somatostatin in H9c2 cells. International journal of cardiology. vol 167. issue 3. 2014-04-02. PMID:22465343. |
the aim of the current study was to delineate the mechanistic insight for the role of sst on β-ar mediated signaling which promotes hypertrophy and apoptosis in rat fetal cardiomyocytes (h9c2 cells). |
2014-04-02 |
2023-08-12 |
rat |
| Rishi K Somvanshi, Xiaofan Qiu, Ujendra Kuma. Isoproterenol induced hypertrophy and associated signaling pathways are modulated by somatostatin in H9c2 cells. International journal of cardiology. vol 167. issue 3. 2014-04-02. PMID:22465343. |
accordingly, sst dependent changes in signaling molecules including second messenger camp, pka/creb as well as mapks including erk and p38 which are key mediators of hypertrophy and apoptosis were analyzed. |
2014-04-02 |
2023-08-12 |
rat |
| Heng Zhou, He-Xin Yang, Yuan Yuan, Wei Deng, Jie-Yu Zhang, Zhou-Yan Bian, Jing Zong, Jia Dai, Qi-Zhu Tan. Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways. Journal of molecular histology. vol 44. issue 3. 2014-03-27. PMID:23417833. |
cardiac remodeling is a key determinant in the clinical course and outcome of heart failure and characterized by cardiac hypertrophy, fibrosis, cardiomyocyte apoptosis and inflammation. |
2014-03-27 |
2023-08-12 |
mouse |
| Heng Zhou, He-Xin Yang, Yuan Yuan, Wei Deng, Jie-Yu Zhang, Zhou-Yan Bian, Jing Zong, Jia Dai, Qi-Zhu Tan. Paeoniflorin attenuates pressure overload-induced cardiac remodeling via inhibition of TGFβ/Smads and NF-κB pathways. Journal of molecular histology. vol 44. issue 3. 2014-03-27. PMID:23417833. |
in conclusion, paeoniflorin attenuated cardiac hypertrophy, fibrosis, apoptosis and inflammation, and improved left ventricular function in pressure overloaded mice. |
2014-03-27 |
2023-08-12 |
mouse |
| Iu V Liskova, S P Salikova, A A Stadniko. [Structural reorganization of the myocardium in ovariectomized rats with experimental heart failure after melatonin administration]. Morfologiia (Saint Petersburg, Russia). vol 144. issue 5. 2014-03-26. PMID:24592713. |
in rats given melatonin for 14 days, there was a regression of pathological changes, with the decrease in the hypertrophy of cmc and their nuclei, reduction of the number of cmc with the signs of apoptosis. |
2014-03-26 |
2023-08-12 |
rat |
| Dong Woo Song, Jae Yong Ryu, Jin Ock Kim, Eun Jeong Kwon, Do Han Ki. The miR-19a/b family positively regulates cardiomyocyte hypertrophy by targeting atrogin-1 and MuRF-1. The Biochemical journal. vol 457. issue 1. 2014-03-07. PMID:24117217. |
in the present study, we examined the hypothesis that the mir-19a/b family acts as a key regulator of cardiac hypertrophy and apoptosis. |
2014-03-07 |
2023-08-12 |
rat |
| Fanghao Lu, Jun Xing, Xinying Zhang, Shiyun Dong, Yajun Zhao, Lina Wang, Hulun Li, Fan Yang, Changqing Xu, Weihua Zhan. Exogenous hydrogen sulfide prevents cardiomyocyte apoptosis from cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry. vol 381. issue 1-2. 2014-02-12. PMID:23660955. |
exogenous hydrogen sulfide prevents cardiomyocyte apoptosis from cardiac hypertrophy induced by isoproterenol. |
2014-02-12 |
2023-08-12 |
Not clear |