| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruey-Lin Chang, Chih-Fen Chang, Da-Tong Ju, Tsung-Jung Ho, Tung-Ti Chang, Jing-Wei Lin, Jia-Chun Li, Shiu-Min Cheng, Cecilia-Hsuan Day, Vijaya Padma Viswanadha, Chih-Yang Huan. Short-term hypoxia upregulated Mas receptor expression to repress the AT Journal of cellular biochemistry. vol 119. issue 3. 2018-10-09. PMID:29052864. |
short-term hypoxia upregulated mas receptor expression to repress the at hypertension-stimulated cardiac hypertrophy and apoptosis play critical roles in the progression of heart failure. |
2018-10-09 |
2023-08-13 |
Not clear |
| Hooi Hooi Ng, Chen Huei Leo, Darnel Prakoso, Chengxue Qin, Rebecca H Ritchie, Laura J Parr. Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes. Scientific reports. vol 7. 2018-10-03. PMID:28067255. |
in the left ventricle, diabetes promoted apoptosis, hypertrophy and fibrosis; serelaxin treatment reversed this ventricular apoptosis and hypertrophy, but had no effect on fibrosis. |
2018-10-03 |
2023-08-13 |
mouse |
| Hooi Hooi Ng, Chen Huei Leo, Darnel Prakoso, Chengxue Qin, Rebecca H Ritchie, Laura J Parr. Serelaxin treatment reverses vascular dysfunction and left ventricular hypertrophy in a mouse model of Type 1 diabetes. Scientific reports. vol 7. 2018-10-03. PMID:28067255. |
in summary, serelaxin reversed diabetes-induced endothelial dysfunction by enhancing no-mediated relaxation in the mouse vasculature and attenuating left ventricular hypertrophy and apoptosis. |
2018-10-03 |
2023-08-13 |
mouse |
| Oscar Orihuela-Rodríguez, Héctor A. Carmona-Ruíz, Fernando Laredo-Sánchez, José Ramón Paniagua-Sierr. Left ventricular hypertrophy, fibrosis heart, and diastolic dysfunction in chronic kidney disease Revista medica del Instituto Mexicano del Seguro Social. vol 55. issue Suppl. 2. 2018-10-02. PMID:29697909. |
myocardial hypertrophy induces the activation of cellular apoptosis signals and activates metabolic pathways able to increase extracellular matrix production up to fibrosis. |
2018-10-02 |
2023-08-13 |
Not clear |
| Xiaoqian Zhou, Yidun Xie, Houan Xiao, Xudong Deng, Yu Wang, Liyuan Jiang, Chen Liu, Rui Zho. MicroRNA-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting Sirtuin 7. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 100. 2018-10-01. PMID:29428666. |
microrna-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting sirtuin 7. |
2018-10-01 |
2023-08-13 |
human |
| Saliha Boumaza, Aicha Belkebir, Samia Neggazi, Hamid Sahraoui, Sihem Berdja, Leila Smail, Yasmina Benazzoug, Ghoti Kacimi, Souhila Aouichat Bouguerr. Therapeutic Role of Resveratrol and Quercetin on Aortic Fibroblasts of Psammomys obesus After Oxidative Stress by Hydrogen Peroxide. American journal of therapeutics. vol 25. issue 3. 2018-09-27. PMID:26766292. |
stressed fibroblasts showed a decrease of cell proliferation and viability, hypertrophy and oncosis, chromatin hypercondensation and increase of cytochrome c release characteristic of apoptosis, activation of erk1/2 and akt pathway, and decreases in p38 mapk pathways marking the cellular resistance. |
2018-09-27 |
2023-08-13 |
Not clear |
| Jia-Wen Li, Xiao-Yun Wang, Xin Zhang, Lei Gao, Li-Feng Wang, Xin-Hua Yi. (‑)‑Epicatechin protects against myocardial ischemia‑induced cardiac injury via activation of the PTEN/PI3K/AKT pathway. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29658565. |
results revealed that myocardial ischemia‑induced mouse cardiac injury was significantly inhibited by epi, as evidenced by decreased myocardial apoptosis, cardiac fibrosis and myocardial hypertrophy and improved cardiac function. |
2018-09-26 |
2023-08-13 |
mouse |
| Shenjie Chen, Bingsheng Yang, Yifei Xu, Yiqing Rong, Yuangang Qi. Protection of Luteolin-7-O-glucoside against apoptosis induced by hypoxia/reoxygenation through the MAPK pathways in H9c2 cells. Molecular medicine reports. vol 17. issue 5. 2018-09-25. PMID:29568918. |
in addition, the flow cytometry analysis showed that the pretreatment of lutg mitigated cell apoptosis induced by hypoxia/reoxygenation in the cardiac hypertrophy model. |
2018-09-25 |
2023-08-13 |
Not clear |
| Madhura Bose, Sadia Almas, Sharma Prabhaka. Wnt signaling and podocyte dysfunction in diabetic nephropathy. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. vol 65. issue 8. 2018-09-10. PMID:28935636. |
the role of podocytes in health and diabetic nephropathy and abnormalities including podocyte hypertrophy, effacement, and apoptosis, and a detailed discussion on the role played by the wnt-β-catenin signaling pathway in podocyte injury and dysfunction are the focus of this review. |
2018-09-10 |
2023-08-13 |
Not clear |
| Wenyi Zhou, Mingyi Zha. How Hippo Signaling Pathway Modulates Cardiovascular Development and Diseases. Journal of immunology research. vol 2018. 2018-08-31. PMID:29577047. |
recent research has demonstrated a novel role of hippo signaling in cardiovascular disease in the context of development, hypertrophy, angiogenesis, regeneration, apoptosis, and autophagy. |
2018-08-31 |
2023-08-13 |
Not clear |
| Bin-Hai Cong, Xiao-Yan Zhu, Xin N. The roles of microRNA-22 in myocardial infarction. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063105. |
in this review, we summarized the recent research progresses, including the regulatory effects of mir-22 in oxidative stress, cardiac apoptosis, autophagy, hypertrophy, fibrosis and regeneration. |
2018-08-29 |
2023-08-13 |
Not clear |
| Fengjiao Sun, Zhiqiang Lu, Yidan Zhang, Shihan Geng, Mengxi Xu, Liman Xu, Yingying Huang, Pengwei Zhuang, Yanjun Zhan. Stage‑dependent changes of β2‑adrenergic receptor signaling in right ventricular remodeling in monocrotaline‑induced pulmonary arterial hypertension. International journal of molecular medicine. vol 41. issue 5. 2018-08-27. PMID:29393391. |
of note, increased levels of cardiomyocyte apoptosis and concomitant rv remodeling, including hypertrophy, dilatation, inflammation and fibrosis, were observed, despite the enhanced rv contractility. |
2018-08-27 |
2023-08-13 |
rat |
| Chih-Chung Feng, Sudhir Pandey, Ching-Yuang Lin, Chia-Yao Shen, Ruey-Lin Chang, Tung-Ti Chang, Ray-Jade Chen, Vijaya Padma Viswanadha, Yueh-Min Lin, Chih-Yang Huan. Cardiac apoptosis induced under high glucose condition involves activation of IGF2R signaling in H9c2 cardiomyoblasts and streptozotocin-induced diabetic rat hearts. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-13. PMID:29136764. |
unregulated igf2r signaling triggers cardiac hypertrophy, apoptosis, and cardiomyopathies. |
2018-08-13 |
2023-08-13 |
rat |
| Jinlin Zhang, Aihua Yang, Yu Wu, Wei Guan, Biao Xiong, Xiaoqing Peng, Xiaojin Wei, Chang Chen, Zhaoguo Li. Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 97. 2018-08-03. PMID:29378386. |
stachydrine (sta) is a naturally occurring compound extracted from a medicinal plant leonuru heterophyllus, which can inhibit the proliferation and induce the apoptosis of breast cancer cells, relieve high glucose-induced endothelial cell senescence and isoproterenol-induced cardiac hypertrophy, and exert antitumor effects. |
2018-08-03 |
2023-08-13 |
rat |
| Leonie R Price, Karen A Lillycrop, Nicola A Irvine, Mark A Hanson, Graham C Burdg. Transcriptome-wide analysis suggests that temporal changes in the relative contributions of hyperplasia, hypertrophy and apoptosis underlie liver growth in pregnant mice. Biology of reproduction. vol 97. issue 5. 2018-08-02. PMID:29091992. |
transcriptome-wide analysis suggests that temporal changes in the relative contributions of hyperplasia, hypertrophy and apoptosis underlie liver growth in pregnant mice. |
2018-08-02 |
2023-08-13 |
mouse |
| Leonie R Price, Karen A Lillycrop, Nicola A Irvine, Mark A Hanson, Graham C Burdg. Transcriptome-wide analysis suggests that temporal changes in the relative contributions of hyperplasia, hypertrophy and apoptosis underlie liver growth in pregnant mice. Biology of reproduction. vol 97. issue 5. 2018-08-02. PMID:29091992. |
these findings suggest that gestational liver growth involves increased mitosis and hypertrophy, and decreased apoptosis contingent on pregnancy stage. |
2018-08-02 |
2023-08-13 |
mouse |
| Aierken Amudong, Aikeremujiang Muheremu, Tuerhongjiang Abudourexit. Hypertrophy of the ligamentum flavum and expression of transforming growth factor beta. The Journal of international medical research. vol 45. issue 6. 2018-07-23. PMID:28635357. |
objective to explore the relationship between cellular apoptosis and hypertrophy of the ligamentum flavum in the lumbar region. |
2018-07-23 |
2023-08-13 |
Not clear |
| Dafeng Yang, Ya Wang, Minna Jiang, Xu Deng, Zhifang Pei, Fei Li, Ke Xia, Lingyan Zhu, Tianlun Yang, Meifang Che. Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells. BioMed research international. vol 2017. 2018-07-20. PMID:29238726. |
downregulation of profilin-1 expression attenuates cardiomyocytes hypertrophy and apoptosis induced by advanced glycation end products in h9c2 cells. |
2018-07-20 |
2023-08-13 |
Not clear |
| Dafeng Yang, Ya Wang, Minna Jiang, Xu Deng, Zhifang Pei, Fei Li, Ke Xia, Lingyan Zhu, Tianlun Yang, Meifang Che. Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells. BioMed research international. vol 2017. 2018-07-20. PMID:29238726. |
cardiomyocytes hypertrophy and apoptosis induced by advanced glycation end products (ages) is the crucial pathological foundation contributing to the onset and development of diabetic cardiomyopathy (dcm). |
2018-07-20 |
2023-08-13 |
Not clear |
| Dafeng Yang, Ya Wang, Minna Jiang, Xu Deng, Zhifang Pei, Fei Li, Ke Xia, Lingyan Zhu, Tianlun Yang, Meifang Che. Downregulation of Profilin-1 Expression Attenuates Cardiomyocytes Hypertrophy and Apoptosis Induced by Advanced Glycation End Products in H9c2 Cells. BioMed research international. vol 2017. 2018-07-20. PMID:29238726. |
here, we report that profilin-1 (pfn-1), a well-known actin-binding protein, serves as a potent regulator in ages-induced cardiomyocytes hypertrophy and apoptosis. |
2018-07-20 |
2023-08-13 |
Not clear |