| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bao Li, Rui-Fang Chi, Fu-Zhong Qin, Xiao-Fei Gu. Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress. Experimental physiology. vol 101. issue 8. 2018-01-01. PMID:27219474. |
little is known about the relationship among myocyte autophagy, hypertrophy, apoptosis and oxidative stress. |
2018-01-01 |
2023-08-13 |
mouse |
| Bao Li, Rui-Fang Chi, Fu-Zhong Qin, Xiao-Fei Gu. Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress. Experimental physiology. vol 101. issue 8. 2018-01-01. PMID:27219474. |
in the present study, we first examined the changes of myocyte autophagy in mice with chronic pressure overload and the relationships between myocyte autophagy and hypertrophy, apoptosis and oxidative stress. |
2018-01-01 |
2023-08-13 |
mouse |
| Bao Li, Rui-Fang Chi, Fu-Zhong Qin, Xiao-Fei Gu. Distinct changes of myocyte autophagy during myocardial hypertrophy and heart failure: association with oxidative stress. Experimental physiology. vol 101. issue 8. 2018-01-01. PMID:27219474. |
the distinct changes were associated with myocyte hypertrophy, apoptosis and oxidative stress. |
2018-01-01 |
2023-08-13 |
mouse |
| Peng Li, Pei-Pei Huang, Yun Yang, Chi Liu, Yan Lu, Fang Wang, Wei Sun, Xiang-Qing Kon. Renal sympathetic denervation attenuates hypertension and vascular remodeling in renovascular hypertensive rats. Journal of applied physiology (Bethesda, Md. : 1985). vol 122. issue 1. 2017-12-19. PMID:27742806. |
right kidney apoptosis and left kidney hypertrophy were not changed by rsd. |
2017-12-19 |
2023-08-13 |
rat |
| Jian Sun, Tao Wei, Shuzhi Bai, Hongtao Zhao, Xiaoqin Liu, Jinfeng Yu, Li Li, Gaochen Song, Hairong Luan, Changqing X. Calcium-sensing receptor-mediated mitogen-activated protein kinase pathway improves the status of transplanted mouse embryonic stem cells in rats with acute myocardial infarction. Molecular and cellular biochemistry. vol 431. issue 1-2. 2017-12-04. PMID:28281186. |
several studies have identified the critical role of calcium-sensing receptors (casrs) in cardiac ischaemia/reperfusion injury and cardiac hypertrophy and have demonstrated that casrs induce myocardial apoptosis by activating mapks. |
2017-12-04 |
2023-08-13 |
mouse |
| Anca Hermenean, Georgiana Gheorghiu, Miruna Silvia Stan, Hildegard Herman, Bianca Onita, Doru Puiu Ardelean, Aurel Ardelean, Mihály Braun, Miklós Zsuga, Sándor Kéki, Marieta Costache, Anca Dinischiot. Biochemical, Histopathological and Molecular Responses in Gills of Leuciscus cephalus Exposed to Metals. Archives of environmental contamination and toxicology. vol 73. issue 4. 2017-12-01. PMID:28939958. |
the induced oxidative stress generated hyperplasia, hypertrophy, and inflammation in the epithelial cells and apoptosis. |
2017-12-01 |
2023-08-13 |
Not clear |
| Feby Savira, Longxing Cao, Ian Wang, Wendi Yang, Kevin Huang, Yue Hua, Beat M Jucker, Robert N Willette, Li Huang, Henry Krum, Zhiliang Li, Qiang Fu, Bing Hui Wan. Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome. PloS one. vol 12. issue 11. 2017-11-28. PMID:29107962. |
apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: implications for cardiorenal syndrome. |
2017-11-28 |
2023-08-13 |
Not clear |
| Feby Savira, Longxing Cao, Ian Wang, Wendi Yang, Kevin Huang, Yue Hua, Beat M Jucker, Robert N Willette, Li Huang, Henry Krum, Zhiliang Li, Qiang Fu, Bing Hui Wan. Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome. PloS one. vol 12. issue 11. 2017-11-28. PMID:29107962. |
in this study, we sought to determine if apoptosis signal-regulated kinase 1 (ask1), an upstream regulator of cellular stress response, mediates cardiac hypertrophy and cardiorenal fibrosis induced by indoxyl sulfate (is) and p-cresol sulfate (pcs) in vitro, and whether ask1 inhibition is beneficial to ameliorate these cellular effects. |
2017-11-28 |
2023-08-13 |
Not clear |
| Ting Wu, Hua Li, Bing Wu, Lei Zhang, San-Wu Wu, Jia-Ning Wang, You-En Zhan. Hydrogen Sulfide Reduces Recruitment of CD11b Cell transplantation. vol 26. issue 5. 2017-11-27. PMID:28185610. |
nahs-treated mice also exhibited reduction in cardiomyocyte apoptosis, interstitial fibrosis, cardiac hypertrophy, and pulmonary edema, as well as overall better survival rates, when compared to controls. |
2017-11-27 |
2023-08-13 |
mouse |
| Yu-Feng Chen, Marthandam Asokan Shibu, Ming-Jen Fan, Ming-Cheng Chen, Vijaya Padma Viswanadha, Yi-Lin Lin, Chao-Hung Lai, Kuan-Ho Lin, Tsung-Jung Ho, Wei-Wen Kuo, Chih-Yang Huan. Purple rice anthocyanin extract protects cardiac function in STZ-induced diabetes rat hearts by inhibiting cardiac hypertrophy and fibrosis. The Journal of nutritional biochemistry. vol 31. 2017-11-24. PMID:27133428. |
diabetes mellitus (dm) often causes chronic inflammation, hypertrophy, apoptosis and fibrosis in the heart and subsequently leads to myocardial remodeling, deteriorated cardiac function and heart failure. |
2017-11-24 |
2023-08-13 |
rat |
| Fan Chen, Dandan Chen, Yubin Zhang, Liang Jin, Han Zhang, Miyang Wan, Tianshu Pan, Xiaochuan Wang, Yuheng Su, Yitao Xu, Junmei Y. Interleukin-6 deficiency attenuates angiotensin II-induced cardiac pathogenesis with increased myocyte hypertrophy. Biochemical and biophysical research communications. vol 494. issue 3-4. 2017-11-22. PMID:29079193. |
immunohistological and serum studies revealed that the extents of cardiac fibrosis, inflammation and apoptosis were reduced in il-6 ko heart during angii-stimulation, while cardiac hypertrophy was obviously induced. |
2017-11-22 |
2023-08-13 |
mouse |
| Chih-Yang Huang, Fa-Lun Lee, Shu-Fen Peng, Kuan-Ho Lin, Ray-Jade Chen, Tsung-Jung Ho, Fu-Jen Tsai, Vijaya V Padma, Wei-Wen Kuo, Chih-Yang Huan. HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy. Journal of cellular physiology. vol 233. issue 2. 2017-11-21. PMID:28383811. |
hypertension-induced cardiac hypertrophy and apoptosis are major characteristics of early-stage heart failure (hf). |
2017-11-21 |
2023-08-13 |
Not clear |
| Chih-Yang Huang, Fa-Lun Lee, Shu-Fen Peng, Kuan-Ho Lin, Ray-Jade Chen, Tsung-Jung Ho, Fu-Jen Tsai, Vijaya V Padma, Wei-Wen Kuo, Chih-Yang Huan. HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy. Journal of cellular physiology. vol 233. issue 2. 2017-11-21. PMID:28383811. |
inhibition of extracellular signal-regulated kinases (erk) efficaciously suppressed angiotensin ii (ang ii)-induced cardiomyocyte hypertrophy and apoptosis by blocking insulin-like growth factor ii receptor (igf-iir) signaling. |
2017-11-21 |
2023-08-13 |
Not clear |
| Yufeng Yao, Qiulun Lu, Zhenkun Hu, Yubin Yu, Qiuyun Chen, Qing K Wan. A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure. Nature communications. vol 8. issue 1. 2017-11-17. PMID:28743963. |
aggf1 protein therapy and mir-183-5p regulate endoplasmic reticulum stress signaling and block endoplasmic reticulum stress-induced apoptosis, cardiac hypertrophy, and heart failure, providing an attractive paradigm for treatment of cardiac hypertrophy and heart failure.endoplasmic reticulum (er) stress promotes cardiac dysfunction. |
2017-11-17 |
2023-08-13 |
mouse |
| Yong-yu Wang, Wei Yu, Bin Zho. Hippo signaling pathway in cardiovascular development and diseases. Yi chuan = Hereditas. vol 39. issue 7. 2017-10-26. PMID:28757472. |
gene knockout and transgenic mouse models have revealed that the hippo signaling pathway is involved in heart development, cardiomyocyte proliferation, apoptosis, hypertrophy and cardiac regeneration. |
2017-10-26 |
2023-08-13 |
mouse |
| Chengming Jia, Hui Chen, Mengying Wei, Xiangjie Chen, Yajun Zhang, Liang Cao, Ping Yuan, Fangyuan Wang, Guodong Yang, Jing M. Gold nanoparticle-based miR155 antagonist macrophage delivery restores the cardiac function in ovariectomized diabetic mouse model. International journal of nanomedicine. vol 12. 2017-10-16. PMID:28744126. |
accordingly, an additional increase of reactive oxygen species, cell apoptosis, cardiac hypertrophy, and fibrosis was observed in the hearts of ovariectomized diabetic mice, in comparison with the diabetes-only group. |
2017-10-16 |
2023-08-13 |
mouse |
| Giacomo Frati, Leonardo Schirone, Isotta Chimenti, Derek Yee, Giuseppe Biondi-Zoccai, Massimo Volpe, Sebastiano Sciarrett. An overview of the inflammatory signalling mechanisms in the myocardium underlying the development of diabetic cardiomyopathy. Cardiovascular research. vol 113. issue 4. 2017-10-02. PMID:28395009. |
diabetes is strongly associated with an increased incidence of heart failure and directly promotes cardiac hypertrophy, fibrosis, and apoptosis. |
2017-10-02 |
2023-08-13 |
Not clear |
| Rokas Navickas, Diane Gal, Aleksandras Laucevičius, Agnė Taparauskaitė, Monika Zdanytė, Paul Holvoe. Identifying circulating microRNAs as biomarkers of cardiovascular disease: a systematic review. Cardiovascular research. vol 111. issue 4. 2017-09-27. PMID:27357636. |
the identified mirs were found to regulate endothelial function and angiogenesis (mir-1, mir-133), vascular smooth muscle cell differentiation (mir-133, mir-145), communication between vascular smooth muscle and endothelial cell to stabilize plaques (mir-145), apoptosis (mir-1, mir-133, mir-499), cardiac myocyte differentiation (mir-1, mir-133, mir-145, mir-208, mir-499), and to repress cardiac hypertrophy (mir-133). |
2017-09-27 |
2023-08-13 |
Not clear |
| Shouji Matsushima, Junya Kuroda, Peiyong Zhai, Tong Liu, Shohei Ikeda, Narayani Nagarajan, Shin-Ichi Oka, Takashi Yokota, Shintaro Kinugawa, Chiao-Po Hsu, Hong Li, Hiroyuki Tsutsui, Junichi Sadoshim. Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling. The Journal of clinical investigation. vol 126. issue 9. 2017-09-26. PMID:27525436. |
transverse aortic constriction activated fyn in the left ventricle (lv), and fyn-deficient mice displayed exacerbated cardiac hypertrophy and dysfunction and increased ros production and apoptosis. |
2017-09-26 |
2023-08-13 |
mouse |
| Diane P Hu, Federico Ferro, Frank Yang, Aaron J Taylor, Wenhan Chang, Theodore Miclau, Ralph S Marcucio, Chelsea S Bahne. Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes. Development (Cambridge, England). vol 144. issue 2. 2017-09-26. PMID:28096214. |
the classic model of endochondral ossification holds that chondrocytes mature to hypertrophy, undergo apoptosis and new bone forms by invading osteoprogenitors. |
2017-09-26 |
2023-08-13 |
Not clear |