| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaohong Wang, Haitao Gu, Wei Huang, Jiangtong Peng, Yutian Li, Liwang Yang, Dongze Qin, Kobina Essandoh, Yigang Wang, Tianqing Peng, Guo-Chang Fa. Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice. Diabetes. vol 65. issue 10. 2017-05-19. PMID:27284111. |
we observed that overexpression of hsp20 significantly attenuated stz-caused cardiac dysfunction, hypertrophy, apoptosis, fibrosis, and microvascular rarefaction. |
2017-05-19 |
2023-08-13 |
mouse |
| Shilpa Rani, Pradeep Kumar Sreenivasaiah, Chunghee Cho, Do Han Ki. Salubrinal Alleviates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Endoplasmic Reticulum Stress Pathway. Molecules and cells. vol 40. issue 1. 2017-05-15. PMID:28152298. |
pathological hypertrophy of the heart is closely associated with endoplasmic reticulum stress (ers), leading to maladaptations such as myocardial fibrosis, induction of apoptosis, and cardiac dysfunctions. |
2017-05-15 |
2023-08-13 |
mouse |
| Hongliang Dai, Guizhi Jia, Meili Lu, Chunguang Liang, Yue Wang, Hongxin Wan. Astragaloside IV inhibits isoprenaline‑induced cardiac fibrosis by targeting the reactive oxygen species/mitogen‑activated protein kinase signaling axis. Molecular medicine reports. vol 15. issue 4. 2017-05-12. PMID:28260010. |
in a preliminary experiment, it was demonstrated that this naturally occurring substance exhibited cardioprotective effects via preventing cardiomyocyte hypertrophy and apoptosis. |
2017-05-12 |
2023-08-13 |
rat |
| Krit Jaikumkao, Anchalee Pongchaidecha, La-Ongdao Thongnak, Keerati Wanchai, Phatchawan Arjinajarn, Varanuj Chatsudthipong, Nipon Chattipakorn, Anusorn Lungkaphi. Amelioration of Renal Inflammation, Endoplasmic Reticulum Stress and Apoptosis Underlies the Protective Effect of Low Dosage of Atorvastatin in Gentamicin-Induced Nephrotoxicity. PloS one. vol 11. issue 10. 2017-05-09. PMID:27727327. |
gentamicin-induced nephrotoxicity was confirmed by marked elevations in serum urea and creatinine, kidney hypertrophy, renal inflammation, fibrosis, er stress and apoptosis and attenuation of creatinine clearance. |
2017-05-09 |
2023-08-13 |
rat |
| Qian-Shi Zhang, Gregory J Eaton, Carol Diallo, Theresa A Freema. Stress-Induced Activation of Apoptosis Signal-Regulating Kinase 1 Promotes Osteoarthritis. Journal of cellular physiology. vol 231. issue 4. 2017-05-01. PMID:26405834. |
recently, we reported that lack of ask1 slowed chondrocyte hypertrophy, terminal differentiation and apoptosis resulting in an increase in trabecular bone formation. |
2017-05-01 |
2023-08-13 |
mouse |
| Hui Li, Linjian Huang, Qianyang Xie, Xieyi Cai, Chi Yang, Shaoyi Wang, Min Zhan. Study on the effects of gradient mechanical pressures on the proliferation, apoptosis, chondrogenesis and hypertrophy of mandibular condylar chondrocytes in vitro. Archives of oral biology. vol 73. 2017-04-26. PMID:27771587. |
study on the effects of gradient mechanical pressures on the proliferation, apoptosis, chondrogenesis and hypertrophy of mandibular condylar chondrocytes in vitro. |
2017-04-26 |
2023-08-13 |
Not clear |
| Hui Li, Linjian Huang, Qianyang Xie, Xieyi Cai, Chi Yang, Shaoyi Wang, Min Zhan. Study on the effects of gradient mechanical pressures on the proliferation, apoptosis, chondrogenesis and hypertrophy of mandibular condylar chondrocytes in vitro. Archives of oral biology. vol 73. 2017-04-26. PMID:27771587. |
to investigate the effects of gradient mechanical pressure on chondrocyte proliferation, apoptosis, and the expression of markers of chondrogenesis and chondrocyte hypertrophy. |
2017-04-26 |
2023-08-13 |
Not clear |
| You-Liang Hsieh, Marthandam Asokan Shibu, Chong-Kuei Lii, Vijaya Padma Viswanadha, Yi-Lin Lin, Chao-Hung Lai, Yu-Feng Chen, Kuan-Ho Lin, Wei-Wen Kuo, Chih-Yang Huan. Andrographis paniculata extract attenuates pathological cardiac hypertrophy and apoptosis in high-fat diet fed mice. Journal of ethnopharmacology. vol 192. 2017-04-21. PMID:27401291. |
andrographis paniculata extract attenuates pathological cardiac hypertrophy and apoptosis in high-fat diet fed mice. |
2017-04-21 |
2023-08-13 |
mouse |
| Anna Bielicka, Beata Zielnik-Jurkiewicz, Edyta Podsiadły, Monika Prochorec-Sobieszek, Joanna Rogulska, Urszula Demko. Role of Chlamydia pneumoniae in the pathogenesis of hypertrophy and adenoid tissue inflammation in children. Otolaryngologia polska = The Polish otolaryngology. vol 70. issue 5. 2017-04-17. PMID:27935539. |
a tropism to epithelial cells and lymphocytes, an inhibition of apoptosis in host cells, an ability to occurrence in persistent form resistant to antibiotic treatment are the features of chlamydia pneumoniae, which can have connection with chronic inflammation of an adenoid tissue and adenoid hypertrophy. |
2017-04-17 |
2023-08-13 |
Not clear |
| Marcos Minicucci, Fernando Oliveira, Priscila Santos, Bertha Polegato, Meliza Roscani, Ana Angelica Fernandes, Beatriz Lustosa, Sergio Paiva, Leonardo Zornoff, Paula Azeved. Pentoxifylline Attenuates Cardiac Remodeling Induced by Tobacco Smoke Exposure. Arquivos brasileiros de cardiologia. vol 106. issue 5. 2017-04-04. PMID:27096523. |
under this condition, inflammation, oxidative stress, energy metabolism abnormalities, apoptosis, and hypertrophy are present. |
2017-04-04 |
2023-08-13 |
Not clear |
| Anna M Papinska, Maira Soto, Christopher J Meeks, Kathleen E Rodger. Long-term administration of angiotensin (1-7) prevents heart and lung dysfunction in a mouse model of type 2 diabetes (db/db) by reducing oxidative stress, inflammation and pathological remodeling. Pharmacological research. vol 107. 2017-03-20. PMID:26956523. |
a(1-7) also prevented cardiomyocyte hypertrophy, apoptosis, lipid accumulation, and decreased diabetes-induced fibrosis and os in the heart tissue. |
2017-03-20 |
2023-08-13 |
mouse |
| Juan Wang, Oi Wah Liew, Arthur Mark Richards, Yei-Tsung Che. Overview of MicroRNAs in Cardiac Hypertrophy, Fibrosis, and Apoptosis. International journal of molecular sciences. vol 17. issue 5. 2017-03-15. PMID:27213331. |
overview of micrornas in cardiac hypertrophy, fibrosis, and apoptosis. |
2017-03-15 |
2023-08-13 |
Not clear |
| Juan Wang, Oi Wah Liew, Arthur Mark Richards, Yei-Tsung Che. Overview of MicroRNAs in Cardiac Hypertrophy, Fibrosis, and Apoptosis. International journal of molecular sciences. vol 17. issue 5. 2017-03-15. PMID:27213331. |
the listed mirna entities are categorized according to the biological relevance of their target genes in relation to three cardiovascular pathologies, namely cardiac hypertrophy, fibrosis, and apoptosis. |
2017-03-15 |
2023-08-13 |
Not clear |
| Wei Xu, Yangli Xie, Quan Wang, Xiaofeng Wang, Fengtao Luo, Siru Zhou, Zuqiang Wang, Junlan Huang, Qiaoyan Tan, Min Jin, Huabing Qi, Junzhou Tang, Liang Chen, Xiaolan Du, Chengguang Zhao, Guang Liang, Lin Che. A novel fibroblast growth factor receptor 1 inhibitor protects against cartilage degradation in a murine model of osteoarthritis. Scientific reports. vol 6. 2017-03-07. PMID:27041213. |
for the in vivo study, intra-articular injection of g141 attenuated the surgical destabilization of the medial meniscus (dmm) induced cartilage destruction and chondrocyte hypertrophy and apoptosis in mice. |
2017-03-07 |
2023-08-13 |
mouse |
| Matthew C White, Li Pang, Xi Yan. MicroRNA-mediated maturation of human pluripotent stem cell-derived cardiomyocytes: Towards a better model for cardiotoxicity? Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 98. issue Pt A. 2017-02-28. PMID:27265266. |
these studies have shown that mirnas are essential to key processes that span the life cycle of a cardiomyocyte, including proliferation, hypertrophy, beating rhythm, and apoptosis. |
2017-02-28 |
2023-08-13 |
human |
| Wen-Qun Li, Xiao-Hui Li, Jie Du, Wang Zhang, Dai Li, Xiao-Ming Xiong, Yuan-Jian L. Rutaecarpine attenuates hypoxia-induced right ventricular remodeling in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 389. issue 7. 2017-02-27. PMID:27052575. |
hypoxia induced an increase of right ventricle systolic pressure (rvsp), ration of rv/lv+s, and rv/tibial length in rats, while cardiac hypertrophy, apoptosis, and fibrosis were detected. |
2017-02-27 |
2023-08-13 |
rat |
| Dominic P Del R. Hippo Signaling in the Heart - Non-Canonical Pathways Impact Growth, Survival and Function. Circulation journal : official journal of the Japanese Circulation Society. vol 80. issue 7. 2017-02-23. PMID:27296131. |
this review summarizes non-canonical targets of rassf1a and mst1 and discusses their role in the context of cardiac hypertrophy, autophagy, apoptosis and function. |
2017-02-23 |
2023-08-13 |
human |
| Shu-Nu Chang Lee, Tsung-Jung Ho, Marthandam Asokan Shibu, Cecilia Hsuan Day, Vijaya Padma Viswanadha, Chao-Hung Lai, Yi-Li Chen, Dennis Jine-Yuan Hsieh, Yueh-Sheng Chen, Chih-Yang Huan. Protective effects of electroacupuncture at LR3 on cardiac hypertrophy and apoptosis in hypertensive rats. Acupuncture in medicine : journal of the British Medical Acupuncture Society. vol 34. issue 3. 2017-02-16. PMID:26566622. |
protective effects of electroacupuncture at lr3 on cardiac hypertrophy and apoptosis in hypertensive rats. |
2017-02-16 |
2023-08-13 |
rat |
| W M Wang, Z Liu, G Che. Effect of siRNA silencing of inducible co-stimulatory molecule on myocardial cell hypertrophy after cardiac infarction in rats. Genetics and molecular research : GMR. vol 15. issue 2. 2017-02-09. PMID:27323062. |
the up-regulation of a series of factors including metalloproteinases, inflammatory factors, and growth factors after primary infarction lead to the hypertrophy, apoptosis, necrosis, and fibroblast proliferation in cardiac muscle tissues. |
2017-02-09 |
2023-08-13 |
rat |
| Jian Tang, Yingbin Ge, Lei Yang, Xinyu Xu, Tao Sui, Dawei Ge, Jun Que, Xiaojian Ca. ER Stress via CHOP Pathway is Involved in FK506-Induced Apoptosis in Rat Fibroblasts. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 39. issue 5. 2017-02-07. PMID:27771715. |
hypertrophic scars (hs) formation results from reduced apoptosis and increased proliferation of fibroblasts. |
2017-02-07 |
2023-08-13 |
rat |