| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huan. Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs. International journal of medical sciences. vol 15. issue 13. 2019-02-26. PMID:30443176. |
tumorous imaginal disc 1 (tid1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (chip) mediated degradation of gαs. |
2019-02-26 |
2023-08-13 |
human |
| Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huan. Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs. International journal of medical sciences. vol 15. issue 13. 2019-02-26. PMID:30443176. |
tid1 also plays a major role in preventing dcm; however, the role of tid1 in isoproterenol (iso)-induced cardiac apoptosis and hypertrophy remains unclear. |
2019-02-26 |
2023-08-13 |
human |
| Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huan. Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs. International journal of medical sciences. vol 15. issue 13. 2019-02-26. PMID:30443176. |
h9c2 cells were pretreated tid1 before iso-induced hypertrophy and apoptosis and then evaluated by ihc, tunel assay, ifc, co-ip, and western blot. |
2019-02-26 |
2023-08-13 |
human |
| Caiwei Wang, Li Yan, Bo Yan, Li Zhou, Wan Sun, Lingying Yu, Fucun Liu, Wenxi Du, Guangping Yu, Zhengyan Hu, Qiang Yuan, Luwei Xiao, Hongwen Li, Peijian Tong, Jida Zhang, Letian Shan, Thomas Effert. Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis. Journal of ethnopharmacology. vol 231. 2019-02-25. PMID:30529425. |
agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis. |
2019-02-25 |
2023-08-13 |
rat |
| Caiwei Wang, Li Yan, Bo Yan, Li Zhou, Wan Sun, Lingying Yu, Fucun Liu, Wenxi Du, Guangping Yu, Zhengyan Hu, Qiang Yuan, Luwei Xiao, Hongwen Li, Peijian Tong, Jida Zhang, Letian Shan, Thomas Effert. Agkistrodon ameliorates pain response and prevents cartilage degradation in monosodium iodoacetate-induced osteoarthritic rats by inhibiting chondrocyte hypertrophy and apoptosis. Journal of ethnopharmacology. vol 231. 2019-02-25. PMID:30529425. |
here, we determined the effects of eaa on the pain behavior and cartilage degradation in vivo and clarified its target genes and proteins associated with chondrocyte hypertrophy and apoptosis in vitro. |
2019-02-25 |
2023-08-13 |
rat |
| Shu-Chun Kuo, Yingxiao Li, Yung-Ze Cheng, Wei-Jing Lee, Juei-Tang Cheng, Kai-Chun Chen. Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221729. |
molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in h9c2 cells. |
2019-02-12 |
2023-08-13 |
Not clear |
| Shu-Chun Kuo, Yingxiao Li, Yung-Ze Cheng, Wei-Jing Lee, Juei-Tang Cheng, Kai-Chun Chen. Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221729. |
oxidative stress can induce cardiac hypertrophy with apoptosis. |
2019-02-12 |
2023-08-13 |
Not clear |
| Shu-Chun Kuo, Yingxiao Li, Yung-Ze Cheng, Wei-Jing Lee, Juei-Tang Cheng, Kai-Chun Chen. Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221729. |
collectively, these results provided a novel perspective that kbro3 induces cardiac hypertrophy without apoptosis at a low dose through the generation of ros, activating the calcineurin/nfat signaling pathway in h9c2 cells. |
2019-02-12 |
2023-08-13 |
Not clear |
| Shu-Chun Kuo, Yingxiao Li, Yung-Ze Cheng, Wei-Jing Lee, Juei-Tang Cheng, Kai-Chun Chen. Molecular mechanisms regarding potassium bromate‑induced cardiac hypertrophy without apoptosis in H9c2 cells. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221729. |
therefore, at a dose <250 µm, kbro3 can be applied as an inducer of cardiac hypertrophy without apoptosis in h9c2 cells. |
2019-02-12 |
2023-08-13 |
Not clear |
| Jun Hyuk Kang, Ho-Sung Lee, Daebeom Park, Yun-Won Kang, Seon Myeong Kim, Jeong-Ryeol Gong, Kwang-Hyun Ch. Context-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network. Scientific reports. vol 7. issue 1. 2019-02-05. PMID:28232733. |
context-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network. |
2019-02-05 |
2023-08-13 |
Not clear |
| Jun Hyuk Kang, Ho-Sung Lee, Daebeom Park, Yun-Won Kang, Seon Myeong Kim, Jeong-Ryeol Gong, Kwang-Hyun Ch. Context-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network. Scientific reports. vol 7. issue 1. 2019-02-05. PMID:28232733. |
apoptosis and hypertrophy of cardiomyocytes are the primary causes of heart failure and are known to be regulated by complex interactions in the underlying intracellular signaling network. |
2019-02-05 |
2023-08-13 |
Not clear |
| Jun Hyuk Kang, Ho-Sung Lee, Daebeom Park, Yun-Won Kang, Seon Myeong Kim, Jeong-Ryeol Gong, Kwang-Hyun Ch. Context-independent essential regulatory interactions for apoptosis and hypertrophy in the cardiac signaling network. Scientific reports. vol 7. issue 1. 2019-02-05. PMID:28232733. |
through extensive computer simulations with various parameter distributions, we revealed the five most essential context-independent regulatory interactions (between: (1) αar and gαq, (2) ip3 and calcium, (3) epac and camk, (4) jnk and nfat, and (5) p38 and nfat) for hypertrophy and apoptosis that were consistently found over all our perturbation analyses. |
2019-02-05 |
2023-08-13 |
Not clear |
| Angela Raucci, Stefania Di Maggio, Francesco Scavello, Alessandro D'Ambrosio, Marco E Bianchi, Maurizio C Capogross. The Janus face of HMGB1 in heart disease: a necessary update. Cellular and molecular life sciences : CMLS. vol 76. issue 2. 2019-01-30. PMID:30306212. |
hmgb1 decreases contractility and induces hypertrophy and apoptosis in cardiomyocytes, stimulates cardiac fibroblast activities, and promotes cardiac stem cell proliferation and differentiation. |
2019-01-30 |
2023-08-13 |
mouse |
| Rayane Brinck Teixeira, Tatiane Evelyn Barboza, Carla Cristina DE Araujo, Rafaela Siqueira, Alexandre Luz DE Castro, Jessica Hellen Poletto Bonetto, Bruna Gazzi DE Lima-Seolin, Cristina Campos Carraro, Adriane Bello-Klein, Pawan K Singal, Alex Sander DA Rosa Arauj. Decreased PGC1- α levels and increased apoptotic protein signaling are associated with the maladaptive cardiac hypertrophy in hyperthyroidism. Journal of biosciences. vol 43. issue 5. 2019-01-29. PMID:30541949. |
hyperthyroidism can lead to the activation of proteins which are associated with inflammation, apoptosis, hypertrophy, and heart failure. |
2019-01-29 |
2023-08-13 |
rat |
| Sadaf Riaz, Asad Zeidan, Fatima Mraich. Myocardial proteases and cardiac remodeling. Journal of cellular physiology. vol 232. issue 12. 2019-01-23. PMID:28255990. |
cardiac hypertrophy (ch), characterized by the enlargement of cardiomyocytes, fibrosis and apoptosis, is one of the leading causes of death worldwide. |
2019-01-23 |
2023-08-13 |
Not clear |
| Nouf T Al-Damry, Hala A Attia, Nawal M Al-Rasheed, Nouf M Al-Rasheed, Raeesa A Mohamad, Maha A Al-Amin, Nduna Dizmiri, Muhammad Attey. Sitagliptin attenuates myocardial apoptosis via activating LKB-1/AMPK/Akt pathway and suppressing the activity of GSK-3β and p38α/MAPK in a rat model of diabetic cardiomyopathy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 107. 2019-01-22. PMID:30099338. |
sitagliptin administration alleviated the decreased phosphorylation of ampk and akt, inactivated the gsk-3β and p38 ampk, therefore, attenuating the apoptosis and hypertrophy induced by hyperglycemia in the diabetic heart. |
2019-01-22 |
2023-08-13 |
rat |
| Robert J Ellis, David M Small, Keng Lim Ng, David A Vesey, Luis Vitetta, Ross S Francis, Glenda C Gobe, Christudas Morai. Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells. Toxicologic pathology. vol 46. issue 4. 2019-01-18. PMID:29683083. |
indoxyl sulfate induces apoptosis and hypertrophy in human kidney proximal tubular cells. |
2019-01-18 |
2023-08-13 |
human |
| Robert J Ellis, David M Small, Keng Lim Ng, David A Vesey, Luis Vitetta, Ross S Francis, Glenda C Gobe, Christudas Morai. Indoxyl Sulfate Induces Apoptosis and Hypertrophy in Human Kidney Proximal Tubular Cells. Toxicologic pathology. vol 46. issue 4. 2019-01-18. PMID:29683083. |
in light of the associated apoptosis, hypertrophy, and metabolic dysfunction, this study demonstrates that is may play a role in the progression of chronic kidney disease. |
2019-01-18 |
2023-08-13 |
human |
| Ruzanna Shkhyan, Ben Van Handel, Jacob Bogdanov, Siyoung Lee, Yifan Yu, Mila Scheinberg, Nicholas W Banks, Sean Limfat, Arthur Chernostrik, Carlos Eduardo Franciozi, Mohammad Parvez Alam, Varghese John, Ling Wu, Gabriel B Ferguson, Ali Nsair, Frank A Petrigliano, C Thomas Vangsness, Kanagasabai Vadivel, Paul Bajaj, Liming Wang, Nancy Q Liu, Denis Evseenk. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair. Annals of the rheumatic diseases. vol 77. issue 5. 2019-01-14. PMID:29436471. |
human adult articular cartilage (ac) has little capacity for repair, and joint surface injuries often result in osteoarthritis (oa), characterised by loss of matrix, hypertrophy and chondrocyte apoptosis. |
2019-01-14 |
2023-08-13 |
mouse |
| Wei You, Zhiming Wu, Fei Ye, Xiangqi W. Cardamonin protects against adverse cardiac remodeling through mTORC1 inhibition in mice with myocardial infarction. Die Pharmazie. vol 73. issue 9. 2019-01-14. PMID:30223933. |
treatment with cardamonin, mi mice displayed that heart hypertrophy and heart dysfunction were alleviated, and cardiac fibrosis, cardiomyocyte size and cell apoptosis of border area were decreased (p<0.05). |
2019-01-14 |
2023-08-13 |
mouse |