| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer E Bruin, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicological sciences : an official journal of the Society of Toxicology. vol 103. issue 2. 2008-06-12. PMID:18203686. |
however, we have shown in an animal model that fetal and neonatal nicotine exposure causes increased beta-cell apoptosis and loss of beta-cell mass, which leads to the development of postnatal dysglycemia and obesity. |
2008-06-12 |
2023-08-12 |
rat |
| Jennifer E Bruin, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicological sciences : an official journal of the Society of Toxicology. vol 103. issue 2. 2008-06-12. PMID:18203686. |
taken together, these data suggest that beta-cell apoptosis following developmental nicotine exposure is mediated via the mitochondria. |
2008-06-12 |
2023-08-12 |
rat |
| C Calderón-Ezquerro, A Sánchez-Reyes, R H Sansores, R Villalobos-Pietrini, O Amador-Muñoz, C Guerrero-Guerra, M E Calderón-Segura, R Uribe-Hernández, S Gómez-Arroy. Cell proliferation kinetics and genotoxicity in lymphocytes of smokers living in Mexico City. Human & experimental toxicology. vol 26. issue 9. 2008-01-31. PMID:17984142. |
alternatively, nicotine and cotinine may possibly induce apoptosis. |
2008-01-31 |
2023-08-12 |
human |
| Reinhard Zeidler, Kaj Albermann, Stephan Lan. Nicotine and apoptosis. Apoptosis : an international journal on programmed cell death. vol 12. issue 11. 2007-12-21. PMID:17846896. |
nicotine and apoptosis. |
2007-12-21 |
2023-08-12 |
Not clear |
| Reinhard Zeidler, Kaj Albermann, Stephan Lan. Nicotine and apoptosis. Apoptosis : an international journal on programmed cell death. vol 12. issue 11. 2007-12-21. PMID:17846896. |
by binding to nicotinic acetylcholine receptors, nicotine deregulates essential biological processes like angiogenesis, apoptosis, and cell-mediated immunity. |
2007-12-21 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. |
2007-12-07 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
exposure of oral epithelial cells to smokeless tobacco extract (ste) induces apoptosis in a dose-dependent manner, until a threshold level of nicotine is achieved upon which apoptosis is inhibited. |
2007-12-07 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
1 mm of nicotine is able to inhibit apoptosis significantly induced by ste in these oral cells. |
2007-12-07 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
exposure of cells to nicotine alone has no effect on apoptosis, but nicotine inhibits apoptosis induced by other agents present in ste. |
2007-12-07 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
using specific inducers of no, we have demonstrated that inhibition of apoptosis by nicotine is through down-regulation of no production. |
2007-12-07 |
2023-08-12 |
Not clear |
| Abhijit G Banerjee, Velliyur K Gopalakrishnan, Jamboor K Vishwanath. Inhibition of nitric oxide-induced apoptosis by nicotine in oral epithelial cells. Molecular and cellular biochemistry. vol 305. issue 1-2. 2007-12-07. PMID:17636461. |
thus, our data clearly indicates that inhibition of no-induced apoptosis by nicotine may lead to tobacco-induced oral carcinogenesis, and implies careful development of modalities in tobacco cessation programs. |
2007-12-07 |
2023-08-12 |
Not clear |
| Ying Zheng, Jeffrey D Ritzenthaler, Jesse Roman, ShouWei Ha. Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression. American journal of respiratory cell and molecular biology. vol 37. issue 6. 2007-12-06. PMID:17600315. |
however, nicotine had no effect on apoptosis of nsclc cells. |
2007-12-06 |
2023-08-12 |
human |
| R Demiralay, N Gürsan, H Erde. Regulation of nicotine-induced apoptosis of pulmonary artery endothelial cells by treatment of N-acetylcysteine and vitamin E. Human & experimental toxicology. vol 26. issue 7. 2007-10-18. PMID:17884964. |
regulation of nicotine-induced apoptosis of pulmonary artery endothelial cells by treatment of n-acetylcysteine and vitamin e. this study investigated the frequency of apoptosis in rat pulmonary artery endothelial cells after intraperitoneal nicotine injection, examining the roles of the inflammatory markers myeloperoxidase (mpo), tumour necrosis factor alpha (tnf-alpha), and vascular endothelial growth factor (vegf) in nicotine-induced vascular damage and the protective effects of two known antioxidant agents, n-acetylcysteine (nac) and vitamin e. female wistar rats were divided into four groups, each composed of nine rats: negative control group, positive control group, nac-treated group (500 mg/kg), and vitamin e-treated group (500 mg/kg). |
2007-10-18 |
2023-08-12 |
rat |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
oral cancer demonstrates a strong epidemiological association with smoking, but little is known about the effect of nicotine on oral cancer cell apoptosis. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
nicotine, a major component of cigarette smoke, can regulate cell proliferation and angiogenesis and suppress apoptosis induced by chemotherapeutic drugs. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
the main aim of this study was to investigate the effects of nicotine on apoptosis induced by cisplatin, which is commonly used to treat advanced oral cancers, in the human oral cancer cell line tca8113. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
the cells were stimulated with nicotine in the presence or absence of cisplatin, and apoptosis was assayed. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
the results showed that nicotine inhibited apoptosis induced by cisplatin. |
2007-10-12 |
2023-08-12 |
human |
| J Xu, H Huang, C Pan, B Zhang, X Liu, L Zhan. Nicotine inhibits apoptosis induced by cisplatin in human oral cancer cells. International journal of oral and maxillofacial surgery. vol 36. issue 8. 2007-10-12. PMID:17611077. |
it was also observed that survivin played a role in the inhibitory effect of nicotine on apoptosis. |
2007-10-12 |
2023-08-12 |
human |