| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingmei Zhang, Opal Kamdar, Wei Le, Glenn D Rosen, Daya Upadhya. Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer. American journal of respiratory cell and molecular biology. vol 40. issue 2. 2009-02-03. PMID:18676776. |
the a549-rho0 cells, which lack mitochondrial dna, demonstrated partial resistance to chemotherapy-induced apoptosis, but blocked the antiapoptotic effects of nicotine. |
2009-02-03 |
2023-08-12 |
Not clear |
| Jingmei Zhang, Opal Kamdar, Wei Le, Glenn D Rosen, Daya Upadhya. Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer. American journal of respiratory cell and molecular biology. vol 40. issue 2. 2009-02-03. PMID:18676776. |
accordingly, we provide evidence that nicotine modulates mitochondrial signaling and inhibits chemotherapy-induced apoptosis in lung cancer. |
2009-02-03 |
2023-08-12 |
Not clear |
| Jingmei Zhang, Opal Kamdar, Wei Le, Glenn D Rosen, Daya Upadhya. Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer. American journal of respiratory cell and molecular biology. vol 40. issue 2. 2009-02-03. PMID:18676776. |
the mitochondrial regulation of nicotine imposes an important mechanism that can critically impair the treatment of lung cancer, because many cancer-therapeutic agents induce apoptosis via the mitochondrial death pathway. |
2009-02-03 |
2023-08-12 |
Not clear |
| Alessandra Cucina, Andrea Fuso, Pierpaolo Coluccia, Antonino Cavallar. Nicotine inhibits apoptosis and stimulates proliferation in aortic smooth muscle cells through a functional nicotinic acetylcholine receptor. The Journal of surgical research. vol 150. issue 2. 2009-01-23. PMID:18295799. |
nicotine inhibits apoptosis and stimulates proliferation in aortic smooth muscle cells through a functional nicotinic acetylcholine receptor. |
2009-01-23 |
2023-08-12 |
Not clear |
| Alessandra Cucina, Andrea Fuso, Pierpaolo Coluccia, Antonino Cavallar. Nicotine inhibits apoptosis and stimulates proliferation in aortic smooth muscle cells through a functional nicotinic acetylcholine receptor. The Journal of surgical research. vol 150. issue 2. 2009-01-23. PMID:18295799. |
the aim of this study was to investigate the effect of nicotine on smc apoptosis. |
2009-01-23 |
2023-08-12 |
Not clear |
| Alessandra Cucina, Andrea Fuso, Pierpaolo Coluccia, Antonino Cavallar. Nicotine inhibits apoptosis and stimulates proliferation in aortic smooth muscle cells through a functional nicotinic acetylcholine receptor. The Journal of surgical research. vol 150. issue 2. 2009-01-23. PMID:18295799. |
in conclusion, we propose that nicotine could lead to the increase of neointimal smcs in vascular lesions by inducing the inhibition of physiological smc apoptosis and the increase of smc proliferation. |
2009-01-23 |
2023-08-12 |
Not clear |
| Piyali Dasgupta, Wasia Rizwani, Smitha Pillai, Rebecca Kinkade, Michelle Kovacs, Shipra Rastogi, Sarmistha Banerjee, Melanie Carless, Esther Kim, Domenico Coppola, Eric Haura, Srikumar Chellappa. Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines. International journal of cancer. vol 124. issue 1. 2009-01-07. PMID:18844224. |
in addition, nicotine can induce angiogenesis and confer resistance to apoptosis. |
2009-01-07 |
2023-08-12 |
human |
| Jennifer E Bruin, Maria A Petre, Sandeep Raha, Katherine M Morrison, Hertzel C Gerstein, Alison C Hollowa. Fetal and neonatal nicotine exposure in Wistar rats causes progressive pancreatic mitochondrial damage and beta cell dysfunction. PloS one. vol 3. issue 10. 2008-12-18. PMID:18852877. |
however, fetal and neonatal nicotine exposure in rats causes mitochondrial-mediated beta cell apoptosis at weaning, and adult-onset dysglycemia, which we hypothesize is related to progressive mitochondrial dysfunction in the pancreas. |
2008-12-18 |
2023-08-12 |
rat |
| L Paleari, A Catassi, M Ciarlo, Z Cavalieri, C Bruzzo, D Servent, A Cesario, L Chessa, M Cilli, F Piccardi, P Granone, P Russ. Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation. Cell proliferation. vol 41. issue 6. 2008-12-17. PMID:19040571. |
nicotine, an active component of cigarettes, can induce cell proliferation, angiogenesis and apoptosis resistance. |
2008-12-17 |
2023-08-12 |
human |
| Rezan Demiralay, Nesrin Gürsan, Havva Erde. The effects of erdosteine, N-acetylcysteine, and vitamin E on nicotine-induced apoptosis of hippocampal neural cells. Journal of cellular biochemistry. vol 104. issue 5. 2008-10-17. PMID:18348255. |
this study investigated the frequency of apoptosis in rat hippocampal neural cells after intraperitoneal nicotine injection, examining the roles of the inflammatory markers myeloperoxidase (mpo) and tumor necrosis factor alpha (tnf-alpha) in nicotine-induced brain damage and the protective effects of three known antioxidant agents, n-acetylcysteine (nac), erdosteine, and vitamin e. female wistar rats were divided into seven groups, each composed of nine rats: 2 negative control groups, 2 positive control groups, one erdosteine-treated group (500 mg/kg), one nac-treated group (500 mg/kg), and one vitamin e-treated group (500 mg/kg). |
2008-10-17 |
2023-08-12 |
rat |
| A Catassi, D Servent, L Paleari, A Cesario, P Russ. Multiple roles of nicotine on cell proliferation and inhibition of apoptosis: implications on lung carcinogenesis. Mutation research. vol 659. issue 3. 2008-10-14. PMID:18495523. |
multiple roles of nicotine on cell proliferation and inhibition of apoptosis: implications on lung carcinogenesis. |
2008-10-14 |
2023-08-12 |
human |
| Harue Sasaya, Takahiro Utsumi, Koji Shimoke, Hitoshi Nakayama, Yoshinobu Matsumura, Kenji Fukunaga, Toshihiko Ikeuch. Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells. Journal of biochemistry. vol 144. issue 2. 2008-10-10. PMID:18477628. |
nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of grp78 during er stress-mediated apoptosis in pc12 cells. |
2008-10-10 |
2023-08-12 |
Not clear |
| Harue Sasaya, Takahiro Utsumi, Koji Shimoke, Hitoshi Nakayama, Yoshinobu Matsumura, Kenji Fukunaga, Toshihiko Ikeuch. Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells. Journal of biochemistry. vol 144. issue 2. 2008-10-10. PMID:18477628. |
we previously reported that nicotine protected against tunicamycin (tm)-induced er stress-mediated apoptosis, but not thapsigargin (tg)-induced apoptosis in pc12 cells. |
2008-10-10 |
2023-08-12 |
Not clear |
| Harue Sasaya, Takahiro Utsumi, Koji Shimoke, Hitoshi Nakayama, Yoshinobu Matsumura, Kenji Fukunaga, Toshihiko Ikeuch. Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells. Journal of biochemistry. vol 144. issue 2. 2008-10-10. PMID:18477628. |
these results suggest that nicotine prevented tm-induced er stress-mediated apoptosis by attenuating an early stage of tm-induced er stress. |
2008-10-10 |
2023-08-12 |
Not clear |
| Jennifer E Bruin, Maria A Petre, Megan A Lehman, Sandeep Raha, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Maternal nicotine exposure increases oxidative stress in the offspring. Free radical biology & medicine. vol 44. issue 11. 2008-07-29. PMID:18343235. |
fetal and neonatal nicotine exposure causes beta-cell apoptosis and loss of beta-cell mass, but the underlying mechanisms are unknown. |
2008-07-29 |
2023-08-12 |
rat |
| Jennifer E Bruin, Maria A Petre, Megan A Lehman, Sandeep Raha, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Maternal nicotine exposure increases oxidative stress in the offspring. Free radical biology & medicine. vol 44. issue 11. 2008-07-29. PMID:18343235. |
these data suggest that beta-cell apoptosis in the fetal and neonatal pancreas may be the result of a direct effect of nicotine via its receptor and that this effect may be mediated through increased oxidative stress. |
2008-07-29 |
2023-08-12 |
rat |
| Theodore A Slotki. If nicotine is a developmental neurotoxicant in animal studies, dare we recommend nicotine replacement therapy in pregnant women and adolescents? Neurotoxicology and teratology. vol 30. issue 1. 2008-06-23. PMID:18380035. |
through its actions on nicotinic cholinergic receptors, nicotine elicits abnormalities of neural cell proliferation and differentiation, promotes apoptosis and produces deficits in the number of neural cells and in synaptic function. |
2008-06-23 |
2023-08-12 |
Not clear |
| Jennifer E Bruin, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicological sciences : an official journal of the Society of Toxicology. vol 103. issue 2. 2008-06-12. PMID:18203686. |
increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. |
2008-06-12 |
2023-08-12 |
rat |
| Jennifer E Bruin, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicological sciences : an official journal of the Society of Toxicology. vol 103. issue 2. 2008-06-12. PMID:18203686. |
however, we have shown in an animal model that fetal and neonatal nicotine exposure causes increased beta-cell apoptosis and loss of beta-cell mass, which leads to the development of postnatal dysglycemia and obesity. |
2008-06-12 |
2023-08-12 |
rat |
| Jennifer E Bruin, Hertzel C Gerstein, Katherine M Morrison, Alison C Hollowa. Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria. Toxicological sciences : an official journal of the Society of Toxicology. vol 103. issue 2. 2008-06-12. PMID:18203686. |
taken together, these data suggest that beta-cell apoptosis following developmental nicotine exposure is mediated via the mitochondria. |
2008-06-12 |
2023-08-12 |
rat |