| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji-Young Jang, Yoon-Kyung Jeon, Yun Choi, Chul-Woo Ki. Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility to TRAIL-induced apoptosis by activating JNK and modulating TRAIL receptor expression. Molecular cancer. vol 9. 2011-01-20. PMID:20875141. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail; apo2 ligand) induces apoptosis in cancer cells but has little effect on normal cells. |
2011-01-20 |
2023-08-12 |
Not clear |
| Yu-Jeong Kim, Su Young Chae, Cheng-Hao Jin, M Sivasubramanian, Sohee Son, Ki Young Choi, Dong-Gyu Jo, Kwangmeyung Kim, Ick Chan Kwon, Kang Choon Lee, Jae Hyung Par. Ionic complex systems based on hyaluronic acid and PEGylated TNF-related apoptosis-inducing ligand for treatment of rheumatoid arthritis. Biomaterials. vol 31. issue 34. 2011-01-18. PMID:20813405. |
the clinical applications of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail), an emerging therapeutic protein for cancer and rheumatoid arthritis (ra), are limited by its instability and short biological half-life. |
2011-01-18 |
2023-08-12 |
mouse |
| S Ben Mkaddem, E Pedruzzi, C Werts, N Coant, M Bens, F Cluzeaud, J M Goujon, E Ogier-Denis, A Vandewall. Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury. Cell death and differentiation. vol 17. issue 9. 2011-01-13. PMID:20224597. |
in this study we show that tlr4 mediates myd88-dependent activation of tnf receptor-associated factor 2, apoptosis signal-regulating kinase 1 (ask1), and jun n-terminal kinase (jnk) and p38 map kinases in ischemic-reperfused kidneys and posthypoxic renal tubule epithelial cells (rtecs). |
2011-01-13 |
2023-08-12 |
mouse |
| Inès Zidi, Souhir Mestiri, Aghleb Bartegi, Nidhal Ben Amo. TNF-alpha and its inhibitors in cancer. Medical oncology (Northwood, London, England). vol 27. issue 2. 2011-01-12. PMID:19277912. |
tumor necrosis factor (tnf)-alpha is implicated in the same time in apoptosis and in cell proliferation. |
2011-01-12 |
2023-08-12 |
human |
| Naira Baregamian, Jun Song, C Eric Bailey, John Papaconstantinou, B Mark Evers, Dai H Chun. Tumor necrosis factor-alpha and apoptosis signal-regulating kinase 1 control reactive oxygen species release, mitochondrial autophagy, and c-Jun N-terminal kinase/p38 phosphorylation during necrotizing enterocolitis. Oxidative medicine and cellular longevity. vol 2. issue 5. 2011-01-12. PMID:20716917. |
tumor necrosis factor (tnf)-alpha is thought to generate reactive oxygen species (ros) and activate the apoptosis signal-regulating kinase 1 (ask1)-c-jun n-terminal kinase (jnk)/p38 pathway. |
2011-01-12 |
2023-08-12 |
Not clear |
| Supriyo De, Somiranjan Ghosh, Raghunath Chatterjee, Y-Q Chen, Linda Moses, Akanchha Kesari, Eric P Hoffman, Sisir K Dutt. PCB congener specific oxidative stress response by microarray analysis using human liver cell line. Environment international. vol 36. issue 8. 2011-01-11. PMID:20638727. |
further in-silico analysis showed that pcb-153 most likely acted through the tnf receptor, leading to oxidative stress involving metallothionein gene families, and causing apoptosis mainly by the fas receptor signaling pathway. |
2011-01-11 |
2023-08-12 |
human |
| Michael Dougan, Stephanie Dougan, Joanna Slisz, Brant Firestone, Matthew Vanneman, Dobrin Draganov, Girija Goyal, Weibo Li, Donna Neuberg, Richard Blumberg, Nir Hacohen, Dale Porter, Leigh Zawel, Glenn Dranof. IAP inhibitors enhance co-stimulation to promote tumor immunity. The Journal of experimental medicine. vol 207. issue 10. 2011-01-10. PMID:20837698. |
the inhibitor of apoptosis proteins (iaps) have recently been shown to modulate nuclear factor κb (nf-κb) signaling downstream of tumor necrosis factor (tnf) family receptors, positioning them as essential survival factors in several cancer cell lines, as indicated by the cytotoxic activity of several novel small molecule iap antagonists. |
2011-01-10 |
2023-08-12 |
mouse |
| Johanna R Abend, Thomas Uldrick, Joseph M Ziegelbaue. Regulation of tumor necrosis factor-like weak inducer of apoptosis receptor protein (TWEAKR) expression by Kaposi's sarcoma-associated herpesvirus microRNA prevents TWEAK-induced apoptosis and inflammatory cytokine expression. Journal of virology. vol 84. issue 23. 2010-12-20. PMID:20844036. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) receptor (tweakr) was among the most consistently and robustly downregulated genes in the presence of kshv mir-k12-10a (mir-k10a). |
2010-12-20 |
2023-08-12 |
human |
| Paul R Coleman, Christopher N Hahn, Matthew Grimshaw, Ying Lu, Xiaochun Li, Peter J Brautigan, Konstanze Beck, Roland Stocker, Mathew A Vadas, Jennifer R Gambl. Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells. Blood. vol 116. issue 19. 2010-12-16. PMID:20664062. |
the cells are resistant to tumor necrosis factor (tnf)α-induced apoptosis, adhesion of neutrophils and mononuclear cells, and the surface (but not cytoplasmic) expression of endothelial leukocyte adhesion molecule 1 and vascular cell adhesion molecule 1. |
2010-12-16 |
2023-08-12 |
Not clear |
| Steven F Abcouwer, Cheng-mao Lin, Ellen B Wolpert, Sumathi Shanmugam, Eric W Schaefer, Willard M Freeman, Alistair J Barber, David A Antonett. Effects of ischemic preconditioning and bevacizumab on apoptosis and vascular permeability following retinal ischemia-reperfusion injury. Investigative ophthalmology & visual science. vol 51. issue 11. 2010-12-07. PMID:20554620. |
using transient ischemia followed by reperfusion (ir) to model ischemic retinal disease, this study compares the effects of ischemic preconditioning (ipc) and therapies targeting vascular endothelial growth factor (vegf) and tumor necrosis factor (tnf)-α on retinal apoptosis, vascular permeability, and mrna expression. |
2010-12-07 |
2023-08-12 |
Not clear |
| Zhongxing Mai, Haiyan Li. Boolean network-based analysis of the apoptosis network: irreversible apoptosis and stable surviving. Journal of theoretical biology. vol 259. issue 4. 2010-12-06. PMID:19422837. |
we found that the external gf signal by itself did not change the apoptotic ratio from randomly chosen initial states when there is no external tnf signal, but can significantly offset apoptosis induced by the tnf signal. |
2010-12-06 |
2023-08-12 |
Not clear |
| Ryutaro Kajihara, Shota Fukushige, Norifumi Shioda, Kano Tanabe, Kohji Fukunaga, Seiji Inu. CaMKII phosphorylates serine 10 of p27 and confers apoptosis resistance to HeLa cells. Biochemical and biophysical research communications. vol 401. issue 3. 2010-12-02. PMID:20851109. |
hela cells expressing dn-pp6 showed increased resistance to apoptosis induced by tnf and cycloheximide. |
2010-12-02 |
2023-08-12 |
Not clear |
| Caroline M Lambert, Mélanie Roy, Jolyane Meloche, Geneviève A Robitaille, Mohsen Agharazii, Darren E Richard, Sébastien Bonne. Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases. American journal of physiology. Heart and circulatory physiology. vol 299. issue 4. 2010-11-30. PMID:20709868. |
we hypothesized that increased circulating levels of tnf promotes vrds by the activation of hif-1, resulting in vsmc proliferation and resistance to apoptosis. |
2010-11-30 |
2023-08-12 |
human |
| Caroline M Lambert, Mélanie Roy, Jolyane Meloche, Geneviève A Robitaille, Mohsen Agharazii, Darren E Richard, Sébastien Bonne. Tumor necrosis factor inhibitors as novel therapeutic tools for vascular remodeling diseases. American journal of physiology. Heart and circulatory physiology. vol 299. issue 4. 2010-11-30. PMID:20709868. |
using human carotid artery smooth muscle cells (casmcs), we demonstrated that tnf (100 ng/ml) activates hif-1 (hif-1α expression), leading to increased casmc proliferation (ki-67 and pcna staining) and resistance to mitochondrial-dependent apoptosis [tetramethylrhodamine methyl ester perchlorate (tmrm), terminal deoxynucleotide transferase-mediated dutp nick end labeling (tunel), annexin-v staining]. |
2010-11-30 |
2023-08-12 |
human |
| Christine Salaün, Christine Leroy, Alice Rousseau, Valérie Boitez, Laurent Beck, Gérard Friedlande. Identification of a novel transport-independent function of PiT1/SLC20A1 in the regulation of TNF-induced apoptosis. The Journal of biological chemistry. vol 285. issue 45. 2010-11-30. PMID:20817733. |
interestingly, pit1 transcription has been shown to be up-regulated by the tumor necrosis factor α (tnf), and we have now investigated the possible involvement of pit1 in tnf-induced apoptosis. |
2010-11-30 |
2023-08-12 |
mouse |
| Dinko Mitrecić, Charles Nicaise, Srećko Gajović, Roland Poche. Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis. Cell transplantation. vol 19. issue 5. 2010-11-22. PMID:20350352. |
apoptosis was detected as the main cause of the loss of transplanted cells and it was influenced by tnf. |
2010-11-22 |
2023-08-12 |
rat |
| Dinko Mitrecić, Charles Nicaise, Srećko Gajović, Roland Poche. Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis. Cell transplantation. vol 19. issue 5. 2010-11-22. PMID:20350352. |
although 3 days after tnf treatment cell death was accelerated, tnf slowed down apoptosis after 7 days. |
2010-11-22 |
2023-08-12 |
rat |
| Keiji Mori, Yoko S Kaneko, Akira Nakashima, Toshiharu Nagatsu, Ikuko Nagatsu, Akira Ot. Peripherally injected lipopolysaccharide induces apoptosis in the subventricular zone of young adult mice. Neuroscience letters. vol 481. issue 2. 2010-11-22. PMID:20600591. |
activation of the tumor necrosis factor (tnf)-alpha-tnfr system played a critical role in fully inducing apoptosis in this pathway. |
2010-11-22 |
2023-08-12 |
mouse |
| Amro Bohsali, Hana Abdalla, Kamalakannan Velmurugan, Volker Brike. The non-pathogenic mycobacteria M. smegmatis and M. fortuitum induce rapid host cell apoptosis via a caspase-3 and TNF dependent pathway. BMC microbiology. vol 10. 2010-11-16. PMID:20831789. |
the non-pathogenic mycobacteria m. smegmatis and m. fortuitum induce rapid host cell apoptosis via a caspase-3 and tnf dependent pathway. |
2010-11-16 |
2023-08-12 |
Not clear |
| Michal Pearl-Yafe, Keren Mizrahi, Jerry Stein, Esma S Yolcu, Ofer Kaplan, Haval Shirwan, Isaac Yaniv, Nadir Askenas. Tumor necrosis factor receptors support murine hematopoietic progenitor function in the early stages of engraftment. Stem cells (Dayton, Ohio). vol 28. issue 7. 2010-11-12. PMID:20506490. |
bm-homed donor cells were insensitive to apoptosis induced by tnf-alpha and fas-ligand and their combination, despite reciprocal inductive cross talk between the tnf and fas receptors. |
2010-11-12 |
2023-08-12 |
mouse |