| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shunbin Ning, Joseph S Pagan. The A20 deubiquitinase activity negatively regulates LMP1 activation of IRF7. Journal of virology. vol 84. issue 12. 2010-06-15. PMID:20392859. |
a20 possesses both deubiquitinase (dub) and ubiquitin e3 ligase activities that are required for termination of toll-like receptor (tlr) signaling leading to nf-kappab activation and for blockage of tumor necrosis factor (tnf)-induced cytotoxicity and apoptosis. |
2010-06-15 |
2023-08-12 |
Not clear |
| Shoubao Yang, Xinzhong W. Identification and functional characterization of a human sTRAIL homolog, CasTRAIL, in an invertebrate oyster Crassostrea ariakensis. Developmental and comparative immunology. vol 34. issue 5. 2010-06-14. PMID:20045024. |
tumor necrosis factor-related apoptosis-inducing ligand (trail/apo2l) is one of the tumor necrosis factor (tnf) superfamily members, participating in many biological processes including apoptosis and immune responses. |
2010-06-14 |
2023-08-12 |
human |
| Ji-Hyun Park, Kyung-Hyun Kim, Soo-Jung Kim, Woo-Ram Lee, Kwang-Gill Lee, Kwan-Kyu Par. Bee venom protects hepatocytes from tumor necrosis factor-alpha and actinomycin D. Archives of pharmacal research. vol 33. issue 2. 2010-06-14. PMID:20195821. |
in the present study, we investigated the anti-apoptotic effect of bv on tumor necrosis factor (tnf)-alpha with actinomycin (act) d induces apoptosis in hepatocytes. |
2010-06-14 |
2023-08-12 |
bee |
| Weizhong Li, Gefei Wang, Heng Zhang, Gang Xin, Dangui Zhang, Jun Zeng, Xiaoxuan Chen, Yanxuan Xu, Youhong Cui, Kangsheng L. Effects of NS1 variants of H5N1 influenza virus on interferon induction, TNFalpha response and p53 activity. Cellular & molecular immunology. vol 7. issue 3. 2010-06-10. PMID:20228833. |
we examined the effects of these mutations on interferon (ifn) induction, tumor-necrosis factor (tnf)alpha response, p53 activity and apoptosis. |
2010-06-10 |
2023-08-12 |
Not clear |
| Clara García Samartino, M Victoria Delpino, Clara Pott Godoy, María Silvia Di Genaro, Karina A Pasquevich, Astrid Zwerdling, Paula Barrionuevo, Patricia Mathieu, Juliana Cassataro, Fernando Pitossi, Guillermo H Giambartolome. Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis. The American journal of pathology. vol 176. issue 3. 2010-06-07. PMID:20093491. |
apoptosis induced by hkba and l-omp19 was completely suppressed in cells of tnf receptor p55-/- mice or when the general caspase inhibitor z-vad-fmk was added to cultures. |
2010-06-07 |
2023-08-12 |
mouse |
| Clara García Samartino, M Victoria Delpino, Clara Pott Godoy, María Silvia Di Genaro, Karina A Pasquevich, Astrid Zwerdling, Paula Barrionuevo, Patricia Mathieu, Juliana Cassataro, Fernando Pitossi, Guillermo H Giambartolome. Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis. The American journal of pathology. vol 176. issue 3. 2010-06-07. PMID:20093491. |
hence, tnf-alpha signaling via tnf receptor (tnfr) 1 through the coupling of caspases determines apoptosis. |
2010-06-07 |
2023-08-12 |
mouse |
| Eswar Shankar, Soumya Krishnamurthy, Rajiv Paranandi, Alakananda Bas. PKCepsilon induces Bcl-2 by activating CREB. International journal of oncology. vol 36. issue 4. 2010-06-04. PMID:20198332. |
we previously demonstrated that overexpression of pkcepsilon in mcf-7 breast cancer cells caused an increase in anti-apoptotic bcl-2 and a decrease in pro-apoptotic bid, attenuating tumor necrosis factor-alpha (tnf)-related apoptosis-inducing ligand (trail)-mediated apoptosis. |
2010-06-04 |
2023-08-12 |
Not clear |
| Sujin Lee, Hideo Yagita, Thomas J Sayers, Esteban Celi. Optimized combination therapy using bortezomib, TRAIL and TLR agonists in established breast tumors. Cancer immunology, immunotherapy : CII. vol 59. issue 7. 2010-06-02. PMID:20213120. |
tnf-related apoptosis-inducing ligand (trail) is a member of the tnf family of cytokines, which can induce apoptosis in various tumor cells by engaging the receptors, dr4 and dr5. |
2010-06-02 |
2023-08-12 |
mouse |
| Kira Bettermann, Mihael Vucur, Johannes Haybaeck, Christiane Koppe, Jörn Janssen, Felix Heymann, Achim Weber, Ralf Weiskirchen, Christian Liedtke, Nikolaus Gassler, Michael Müller, Rita de Vos, Monika Julia Wolf, Yannick Boege, Gitta Maria Seleznik, Nicolas Zeller, Daniel Erny, Thomas Fuchs, Stefan Zoller, Stefano Cairo, Marie-Annick Buendia, Marco Prinz, Shizuo Akira, Frank Tacke, Mathias Heikenwalder, Christian Trautwein, Tom Luedd. TAK1 suppresses a NEMO-dependent but NF-kappaB-independent pathway to liver cancer. Cancer cell. vol 17. issue 5. 2010-06-01. PMID:20478530. |
tak1-mediated cancer suppression is exerted through activating nf-kappab in response to tumor necrosis factor (tnf) and through preventing caspase-3-dependent hepatocyte and cholangiocyte apoptosis. |
2010-06-01 |
2023-08-12 |
Not clear |
| Kuzhuvelil B Harikumar, Bokyung Sung, Manoj K Pandey, Sushovan Guha, Sunil Krishnan, Bharat B Aggarwa. Escin, a pentacyclic triterpene, chemosensitizes human tumor cells through inhibition of nuclear factor-kappaB signaling pathway. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20103608. |
whether examined by esterase staining, phosphatidyl-serine staining, dna breakage, or caspase-mediated poly(adp-ribose) polymerase cleavage, escin potentiated tumor necrosis factor (tnf)-induced apoptosis but inhibited tumor cell invasion. |
2010-05-28 |
2023-08-12 |
human |
| Noboru Uchide, Hiroo Toyod. Current status of monocyte differentiation-inducing (MDI) factors derived from human fetal membrane chorion cells undergoing apoptosis after influenza virus infection. Gene regulation and systems biology. vol 1. 2010-05-20. PMID:19936095. |
influenza virus infection induces apoptosis and the expression of a set of pro-inflammatory cytokine genes, such as interleukin (il)-6, tumor necrosis factor (tnf)-alpha, interferon (ifn)-beta and ifn-gamma, in cultured human fetal membrane chorion cells. |
2010-05-20 |
2023-08-12 |
human |
| Mani Alikhani, Sayon Roy, Dana T Grave. FOXO1 plays an essential role in apoptosis of retinal pericytes. Molecular vision. vol 16. 2010-05-11. PMID:20300563. |
studies were performed to investigate pathways through which an advanced glycation endproduct and tumor necrosis factor (tnf)-alpha stimulate apoptosis in retinal pericytes through the activation of the pro-apoptotic transcription factor forkhead box o1 (foxo1). |
2010-05-11 |
2023-08-12 |
Not clear |
| Chao Zheng, Venkataraman Kabaleeswaran, Yaya Wang, Genhong Cheng, Hao W. Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation. Molecular cell. vol 38. issue 1. 2010-05-07. PMID:20385093. |
traf1/2 and ciap1/2 are members of the tnf receptor-associated factor (traf) and the inhibitor of apoptosis (iap) families, respectively. |
2010-05-07 |
2023-08-12 |
Not clear |
| Franky Van Herreweghe, Nele Festjens, Wim Declercq, Peter Vandenabeel. Tumor necrosis factor-mediated cell death: to break or to burst, that's the question. Cellular and molecular life sciences : CMLS. vol 67. issue 10. 2010-05-05. PMID:20198502. |
in this review, we discuss the signal-transduction pathways of three major cellular responses induced by tumor necrosis factor (tnf): cell survival through nf-kappab activation, apoptosis, and necrosis. |
2010-05-05 |
2023-08-12 |
human |
| Sowmyalakshmi Srinivasan, Raj Kumar, Srinivas Koduru, Aaditya Chandramouli, Chendil Damodara. Inhibiting TNF-mediated signaling: a novel therapeutic paradigm for androgen independent prostate cancer. Apoptosis : an international journal on programmed cell death. vol 15. issue 2. 2010-05-03. PMID:19851870. |
the tumor necrosis factor (tnf) receptor super family comprises of members that induce two distinct signaling cascades, leading to either cell survival or apoptosis. |
2010-05-03 |
2023-08-12 |
Not clear |
| Ioannis Chatzidakis, Clio Mamalak. T cells as sources and targets of TNF: implications for immunity and autoimmunity. Current directions in autoimmunity. vol 11. 2010-05-03. PMID:20173390. |
tnf has an impact on all aspects of t cell biology such as development in the thymus, peripheral homeostasis, primary antigenic responses, apoptosis, effector functions, memory cell formation and tolerance induction and maintenance. |
2010-05-03 |
2023-08-12 |
mouse |
| Hong Xu, Xin-Tian Lai, Kai Ye, Hui-Wen Ma, Kui Hon. [Expression of a DNA fragment encoding the active domain of human TNF related apoptosis inducing ligand in pichia pastoris]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology. vol 19. issue 2. 2010-04-29. PMID:15966315. |
[expression of a dna fragment encoding the active domain of human tnf related apoptosis inducing ligand in pichia pastoris]. |
2010-04-29 |
2023-08-12 |
human |
| Nikolai Klymiuk, Bernhard Aigner, Gottfried Brem, Eckhard Wol. Genetic modification of pigs as organ donors for xenotransplantation. Molecular reproduction and development. vol 77. issue 3. 2010-04-29. PMID:19998476. |
these modifications include expression of human complement regulatory proteins, cd39, endothelial protein c receptor, heme oxygenase 1, thrombomodulin, tissue factor pathway inhibitor as well as modulators of the cellular immune system such as human tnf alpha-related apoptosis inducing ligand, hla-e/beta-2-microglobulin, and ctla-4ig. |
2010-04-29 |
2023-08-12 |
human |
| Eugene S Han, Samrawit Mekasha, Robin R Ingall. Fibroblast growth factor-inducible 14 (Fn14) is expressed in the lower genital tract and may play a role in amplifying inflammation during infection. Journal of reproductive immunology. vol 84. issue 1. 2010-04-13. PMID:19963275. |
tnf-like weak inducer of apoptosis (tweak) is a member of the tumor necrosis factor (tnf) cytokine superfamily which regulates a number of cellular responses, including inflammation and proliferation. |
2010-04-13 |
2023-08-12 |
Not clear |
| Zafar Mahmood, Yogeshwer Shukl. Death receptors: targets for cancer therapy. Experimental cell research. vol 316. issue 6. 2010-03-30. PMID:20026107. |
drs are the members of tumor necrosis factor (tnf) receptor superfamily, known to be involved in apoptosis signaling, independent of p53 tumor-supressor gene. |
2010-03-30 |
2023-08-12 |
Not clear |