| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Gonelli, D Milani, E Rimondi, R Voltan, V Grill, C Celeghin. Activation of PKC-epsilon counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members. European journal of histochemistry : EJH. vol 53. issue 3. 2009-11-24. PMID:19864212. |
activation of pkc-epsilon counteracts maturation and apoptosis of hl-60 myeloid leukemic cells in response to tnf family members. |
2009-11-24 |
2023-08-12 |
Not clear |
| Jeannette Gerspach, Klaus Pfizenmaier, Harald Wajan. Improving TNF as a cancer therapeutic: tailor-made TNF fusion proteins with conserved antitumor activity and reduced systemic side effects. BioFactors (Oxford, England). vol 35. issue 4. 2009-11-13. PMID:19484741. |
tumor necrosis factor (tnf) is highly pleiotropic cytokine regulating diverse cellular processes such as proliferation, cell migration, angiogenesis, differentiation, apoptosis, necrosis, but also survival. |
2009-11-13 |
2023-08-12 |
Not clear |
| Mahanama De Zoysa, Chamilani Nikapitiya, Dong-Oh Moon, Ilson Whang, Gi-Young Kim, Jehee Le. A novel Fas ligand in mollusk abalone: molecular characterization, immune responses and biological activity of the recombinant protein. Fish & shellfish immunology. vol 27. issue 3. 2009-11-12. PMID:19576285. |
fas ligand is a member of the tnf superfamily that plays an important role by inducing apoptosis and homeostasis of immune responses. |
2009-11-12 |
2023-08-12 |
human |
| D Legarda-Addison, H Hase, M A O'Donnell, A T Tin. NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling. Cell death and differentiation. vol 16. issue 9. 2009-11-03. PMID:19373245. |
without nemo, rip1 associates with caspase-8 resulting in rapid tumor necrosis factor (tnf)-induced apoptosis. |
2009-11-03 |
2023-08-12 |
Not clear |
| R Audo, B Combe, B Coulet, J Morel, M Hahn. The pleiotropic effect of TRAIL on tumor-like synovial fibroblasts from rheumatoid arthritis patients is mediated by caspases. Cell death and differentiation. vol 16. issue 9. 2009-11-03. PMID:19407827. |
the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) has gained much attention as a possible therapeutic reagent for the treatment of tumors, as trail was originally described to induce apoptosis specifically in cancer cells, but not in normal cells. |
2009-11-03 |
2023-08-12 |
human |
| R C Elders, S J Baines, B Catchpol. Susceptibility of the C2 canine mastocytoma cell line to the effects of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). Veterinary immunology and immunopathology. vol 130. issue 1-2. 2009-11-02. PMID:19185923. |
tumor necrosis factor-related apoptosis-inducing ligand (trail) is a member of the tnf family, which preferentially induces apoptosis in cells that have undergone malignant transformation. |
2009-11-02 |
2023-08-12 |
human |
| Martina Klarić, Sun Tao, Veronika Stoka, Boris Turk, Vito Tur. Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells. Biochimica et biophysica acta. vol 1794. issue 9. 2009-10-22. PMID:19409515. |
the tumor necrosis factor (tnf) is a cytokine known to be an important mediator of apoptosis and inflammation. |
2009-10-22 |
2023-08-12 |
Not clear |
| Martina Klarić, Sun Tao, Veronika Stoka, Boris Turk, Vito Tur. Cysteine cathepsins are not critical for TNF-alpha-induced cell death in T98G and U937 cells. Biochimica et biophysica acta. vol 1794. issue 9. 2009-10-22. PMID:19409515. |
tnf apoptosis has been known for a number of years to be critically dependent on caspases; however, recently it has been suggested that cysteine cathepsins might also be involved in the pathway. |
2009-10-22 |
2023-08-12 |
Not clear |
| Lang Bai, Wenshu Chen, Wenjie Chen, Xia Wang, Hong Tang, Yong Li. IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells. Molecular cancer therapeutics. vol 8. issue 6. 2009-10-20. PMID:19509265. |
smac mimetics (sm) have been recently reported to kill cancer cells through the extrinsic apoptosis pathway mediated by autocrine tumor necrosis factor (tnf). |
2009-10-20 |
2023-08-12 |
Not clear |
| Lang Bai, Wenshu Chen, Wenjie Chen, Xia Wang, Hong Tang, Yong Li. IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells. Molecular cancer therapeutics. vol 8. issue 6. 2009-10-20. PMID:19509265. |
our results show that through tnf autocrine, sm induces an ikkbeta-mediated nf-kappab activation pathway that protects cancer cells against sm-induced apoptosis, and thus, nf-kappab blockage could be an effective approach for improving the anticancer value of sm. |
2009-10-20 |
2023-08-12 |
Not clear |
| Gen Sheng W. TRAIL as a target in anti-cancer therapy. Cancer letters. vol 285. issue 1. 2009-10-14. PMID:19299078. |
the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf superfamily that can initiate apoptosis through the activation of their death receptors. |
2009-10-14 |
2023-08-12 |
human |
| Rebecca A Csomos, Graham F Brady, Colin S Ducket. Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2. The Journal of biological chemistry. vol 284. issue 31. 2009-10-14. PMID:19506082. |
inhibitor of apoptosis (iap) proteins are key regulators of intracellular signaling that interact with tumor necrosis factor (tnf) receptor superfamily members as well as proapoptotic molecules such as smac/diablo and caspases. |
2009-10-14 |
2023-08-12 |
Not clear |
| Manikuntala Kundu, Sushil Kumar Pathak, Kuldeep Kumawat, Sanchita Basu, Gargi Chatterjee, Shresh Pathak, Takuya Noguchi, Kohsuke Takeda, Hidenori Ichijo, Christine B F Thien, Wallace Y Langdon, Joyoti Bas. A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis. Nature immunology. vol 10. issue 8. 2009-10-14. PMID:19597496. |
here we establish a link between the release of tumor necrosis factor (tnf) and mycobacteria-mediated macrophage apoptosis. |
2009-10-14 |
2023-08-12 |
Not clear |
| N F Ramia, S I Kreydiyye. TNF-alpha modulates the Na+/ K+ ATPase and the Na+K+2Cl- symporter in LLC-PK cells. European journal of clinical investigation. vol 39. issue 4. 2009-10-09. PMID:19292883. |
as tnf is known to induce both apoptosis and cell survival, this work investigated the effect and mechanism of action of tnf-alpha on the na(+)/k(+) atpase and the na(+)k(+)2cl(-) symporter using llc-pk(1) cells, a porcine renal proximal tubules cell line. |
2009-10-09 |
2023-08-12 |
Not clear |
| S A Kalashnikova, A N Goryachev, V V Novochadov, A I Shchyogole. Thyroid modulation of TNF-dependent apoptosis and formation of chronic liver disease in endogenous intoxication in rats. Bulletin of experimental biology and medicine. vol 147. issue 2. 2009-10-09. PMID:19513431. |
thyroid modulation is realized as more intense induction of tnf apoptosis in the cells and stimulation of microcirculatory disorders at the expense of nitroxide synthase expression. |
2009-10-09 |
2023-08-12 |
rat |
| Zhiqiang Bai, Ling Li, Bin Wang, Zhijun Liu, Haitao Wang, Zhiyong Yan, Dongmeng Qian, Shouyi Ding, Xuxia Son. Effect of inducible expressed human cytomegalovirus immediate early 86 protein on cell apoptosis. Bioscience, biotechnology, and biochemistry. vol 73. issue 6. 2009-10-06. PMID:19502735. |
our results indicate that ie86 inhibits tumor necrosis factor (tnf)-alpha induced apoptosis and that the anti-apoptotic activity of this viral protein correlates with its expression levels. |
2009-10-06 |
2023-08-12 |
human |
| Liesbeth Huys, Filip Van Hauwermeiren, Lien Dejager, Eline Dejonckheere, Stefan Lienenklaus, Siegfried Weiss, Georges Leclercq, Claude Liber. Type I interferon drives tumor necrosis factor-induced lethal shock. The Journal of experimental medicine. vol 206. issue 9. 2009-10-05. PMID:19687227. |
after tnf injection, ifnar-1(-/-) mice produced less il-6, had less bowel damage, and had less apoptosis of enterocytes and hepatocytes compared with wild-type (wt) mice. |
2009-10-05 |
2023-08-12 |
mouse |
| Lars Vereecke, Rudi Beyaert, Geert van Lo. The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology. Trends in immunology. vol 30. issue 8. 2009-10-01. PMID:19643665. |
moreover, a20 also regulates tumor necrosis factor (tnf)-induced apoptosis. |
2009-10-01 |
2023-08-12 |
human |
| Nadia Corazza, Daniela Kassahn, Sabine Jakob, Anastasia Badmann, Thomas Brunne. TRAIL-induced apoptosis: between tumor therapy and immunopathology. Annals of the New York Academy of Sciences. vol 1171. 2009-09-23. PMID:19723037. |
the death ligand members of the tumor necrosis factor (tnf) family are potent inducers of apoptosis in a variety of cell types. |
2009-09-23 |
2023-08-12 |
Not clear |
| Anak A S S K Dharmapatni, Malcolm D Smith, David M Findlay, Christopher A Holding, Andreas Evdokiou, Michael J Ahern, Helen Weedon, Paul Chen, Gavin Screaton, Xiao N Xu, David R Hayne. Elevated expression of caspase-3 inhibitors, survivin and xIAP correlates with low levels of apoptosis in active rheumatoid synovium. Arthritis research & therapy. vol 11. issue 1. 2009-09-09. PMID:19171073. |
tumour necrosis factor-related apoptosis-inducing ligand (trail) is a tumour necrosis factor (tnf) family member capable of inducing apoptosis in many cell types. |
2009-09-09 |
2023-08-12 |
Not clear |