| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiang Liu, Murad Ghanim, Lei Xue, Christopher D Brown, Ivan Iossifov, Cesar Angeletti, Sujun Hua, Nicolas Nègre, Michael Ludwig, Thomas Stricker, Hikmat A Al-Ahmadie, Maria Tretiakova, Robert L Camp, Montse Perera-Alberto, David L Rimm, Tian Xu, Andrey Rzhetsky, Kevin P Whit. Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer. Science (New York, N.Y.). vol 323. issue 5918. 2009-03-09. PMID:19164706. |
drosophila spop mediates degradation of the jun kinase phosphatase puckered, thereby inducing tumor necrosis factor (tnf)/eiger-dependent apoptosis. |
2009-03-09 |
2023-08-12 |
drosophila_melanogaster |
| Frank Y Ma, Jian Liu, A Richard Kitching, Carl L Manthey, David J Nikolic-Paterso. Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney. American journal of physiology. Renal physiology. vol 296. issue 1. 2009-03-06. PMID:18987110. |
complete inhibition of renal macrophage accumulation prevented upregulation of the macrophage-associated proinflammatory mediators, tumor necrosis factor (tnf)-alpha and matrix metalloproteinase-12, and significantly reduced tubular apoptosis. |
2009-03-06 |
2023-08-12 |
rat |
| Hua Zhao, Guo-Chun Wan. [The expression of tumor necrosis factor-related apoptosis inducing ligand and its receptors in muscle tissue of inflammatory myopathies]. Zhonghua nei ke za zhi. vol 47. issue 5. 2009-03-03. PMID:18953943. |
the purpose of this study is to analyse the expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) and its receptors in muscle tissue from patients with idiopathic inflammatory myopathies ( iim) and investigate the possible role of trail system in the pathogenesis of iim. |
2009-03-03 |
2023-08-12 |
Not clear |
| Fukumi Furukawa, Masahiko Mut. Ethnic differences in immunogenetic features and photosensitivity of cutaneous lupus erythematosus. Archives of dermatological research. vol 301. issue 1. 2009-02-24. PMID:18797890. |
our present understanding is that an axis of photosensitivity, anti-ro/ss-a antibodies and apoptosis via tnf are the best (markers) to verify the contribution of genetics in scle, let, and other cles. |
2009-02-24 |
2023-08-12 |
human |
| Anna Korzekwa, Shuko Murakami, Izabela Wocławek-Potocka, Mamadou M Bah, Kiyoshi Okuda, Dariusz J Skarzynsk. The influence of tumor necrosis factor alpha (TNF) on the secretory function of bovine corpus luteum: TNF and its receptors expression during the estrous cycle. Reproductive biology. vol 8. issue 3. 2009-02-13. PMID:19092986. |
moreover, 1 microg of tnf induced apoptosis and increased (p<0.05) caspase-3 activity in the cls collected during the late luteal phase. |
2009-02-13 |
2023-08-12 |
cattle |
| Anna Korzekwa, Shuko Murakami, Izabela Wocławek-Potocka, Mamadou M Bah, Kiyoshi Okuda, Dariusz J Skarzynsk. The influence of tumor necrosis factor alpha (TNF) on the secretory function of bovine corpus luteum: TNF and its receptors expression during the estrous cycle. Reproductive biology. vol 8. issue 3. 2009-02-13. PMID:19092986. |
a low concentration of tnf stimulated in vivo luteolytic factors such as pgf(2alpha), ltc(4) and no as well as induced apoptosis; whereas the high concentration of tnf stimulated a survival pathway in the bovine cl increasing luteal content of p(4) and pge(2). |
2009-02-13 |
2023-08-12 |
cattle |
| T Lwin, L A Crespo, A Wu, S Dessureault, H B Shu, L C Moscinski, E Sotomayor, W S Dalton, J Ta. Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis. Leukemia. vol 23. issue 1. 2009-02-06. PMID:18843286. |
lymphoma cell adhesion-induced expression of b cell-activating factor of the tnf family in bone marrow stromal cells protects non-hodgkin's b lymphoma cells from apoptosis. |
2009-02-06 |
2023-08-12 |
Not clear |
| Ling Liu, Hai-Bo Qiu, Yi Yang, Lian Wang, Hui-Min Ding, Hong-Peng L. Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat. Archives of biochemistry and biophysics. vol 481. issue 1. 2009-02-06. PMID:18940180. |
meanwhile, nuclear factor (nf)-kappab-dna-binding activity, tumor necrosis factor (tnf)-alpha mrna, and pneumocytic apoptosis were significantly increased. |
2009-02-06 |
2023-08-12 |
rat |
| Sudeshna Seal, David M Hockenbery, Emily Y Spaulding, Hans-Peter Kiem, Nissa Abbassi, H Joachim Dee. Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals. Experimental hematology. vol 36. issue 12. 2009-01-22. PMID:18838202. |
clonal marrow cells from patients with early myelodysplastic syndrome (mds) undergo apoptosis in response to tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail). |
2009-01-22 |
2023-08-12 |
human |
| Gautam Sethi, Kwang Seok Ahn, Bokyung Sung, Ajaikumar B Kunnumakkara, Madan M Chaturvedi, Bharat B Aggarwa. SH-5, an AKT inhibitor potentiates apoptosis and inhibits invasion through the suppression of anti-apoptotic, proliferative and metastatic gene products regulated by IkappaBalpha kinase activation. Biochemical pharmacology. vol 76. issue 11. 2009-01-09. PMID:18606397. |
we found that sh-5 potentiated the apoptosis induced by tumor necrosis factor (tnf), as indicated by intracellular esterase staining, annexin v staining, and caspase-3 activation. |
2009-01-09 |
2023-08-12 |
Not clear |
| Huafei Zou, Shuxuan Zhan, Kaiming Ca. Apoptotic activity of genistein on human lung adenocarcinoma SPC-A-1 cells and preliminary exploration of its mechanisms using microarray. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 62. issue 9. 2008-12-29. PMID:18295443. |
these genes, mainly consisting of the bcl-2 family and tnf ligand and receptor family, are involved in regulation of the apoptosis process. |
2008-12-29 |
2023-08-12 |
human |
| Tony Navas, Li Zhou, Myka Estes, Edwin Haghnazari, Aaron N Nguyen, Yongkai Mo, Perry Pahanish, Mani Mohindru, Tim Cao, Linda S Higgins, Leonidas C Platanias, Alan List, Amit Verma, T Bhagat, S Gajavelli, S Kambhampat. Inhibition of p38alpha MAPK disrupts the pathological loop of proinflammatory factor production in the myelodysplastic syndrome bone marrow microenvironment. Leukemia & lymphoma. vol 49. issue 10. 2008-12-29. PMID:18949619. |
treatment with scio-469 inhibits tnf secretion in primary mds bone marrow cells and protects cytogenetically normal progenitors from apoptosis ex vivo. |
2008-12-29 |
2023-08-12 |
Not clear |
| Sefat E Khuda, William M Loo, Siegfried Janz, Brian Van Ness, Loren D Erickso. Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors. Journal of immunology (Baltimore, Md. : 1950). vol 181. issue 11. 2008-12-29. PMID:19017943. |
examination of pc viability revealed that c-myc triggered apoptosis only upon final maturation when ab is secreted and is resistant to the survival factor baff (b cell-activating factor belonging to the tnf family). |
2008-12-29 |
2023-08-12 |
mouse |
| Xiao Li, Quan Pu, Wei-ming Shen, K Tohyama, H J Dee. [Biologic changes in MDS-L cell line induced by As2O3 and/or TRAIL]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 25. issue 10. 2008-12-22. PMID:15634594. |
to investigate the biological changes in myelodysplastic syndromes (mds) myeloid blast cell line mds-l after different duration and concentration of as2o3/trail (tnf related apoptosis inducing ligand) treatment. |
2008-12-22 |
2023-08-12 |
Not clear |
| Dieter Seebach, James Gardine. Beta-peptidic peptidomimetics. Accounts of chemical research. vol 41. issue 10. 2008-12-16. PMID:18578513. |
this account presents examples of beta-peptidic compounds binding, as agonists or antagonists (inhibitors), to (i) major histocompatibility complex (mhc) proteins (immune response), (ii) the lipid-transport protein sr-b1 (cholesterol uptake from the small intestine), (iii) the core (1-60) of interleukin-8 (inflammation), (iv) the oncoprotein rdm2, (v) the hivgp41 fusion protein, (vi) g-protein-coupled somatostatin hsst receptors, (vii) the tnf immune response receptor cd40 (apoptosis), and (viii) dna. |
2008-12-16 |
2023-08-12 |
Not clear |
| S Barisic, E Strozyk, N Peters, H Walczak, D Kulm. Identification of PP2A as a crucial regulator of the NF-kappaB feedback loop: its inhibition by UVB turns NF-kappaB into a pro-apoptotic factor. Cell death and differentiation. vol 15. issue 11. 2008-12-12. PMID:18583989. |
this paradoxical effect is associated with nf-kappab-dependent pronounced secretion of tumour necrosis factor-alpha (tnf) which activates tnf-r1 in an autocrine fashion to enhance uvb-induced apoptosis. |
2008-12-12 |
2023-08-12 |
Not clear |
| Karen L Edelblum, Jeremy A Goettel, Tatsuki Koyama, Steven J McElroy, Fang Yan, D Brent Pol. TNFR1 promotes tumor necrosis factor-mediated mouse colon epithelial cell survival through RAF activation of NF-kappaB. The Journal of biological chemistry. vol 283. issue 43. 2008-12-11. PMID:18713739. |
we demonstrate that tnf activation of tnf receptor (r)1 stimulates both pro- and anti-apoptotic signaling pathways in the colon epithelium; however, tnfr1 protects against colon epithelial cell apoptosis following tnf exposure. |
2008-12-11 |
2023-08-12 |
mouse |
| Preetha Anand, Ajaikumar B Kunnumakkara, Kuzhuvelil B Harikumar, Kwang Seok Ahn, Vladimir Badmaev, Bharat B Aggarwa. Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis. Cancer research. vol 68. issue 21. 2008-12-08. PMID:18974130. |
nf-kappab inhibition by picroliv leads to suppression of nf-kappab-regulated proteins, including those linked with cell survival (inhibitor of apoptosis protein 1, bcl-2, bcl-xl, survivin, and tnf receptor-associated factor 2), proliferation (cyclin d1 and cyclooxygenase-2), angiogenesis (vascular endothelial growth factor), and invasion (intercellular adhesion molecule-1 and matrix metalloproteinase-9). |
2008-12-08 |
2023-08-12 |
Not clear |
| Preetha Anand, Ajaikumar B Kunnumakkara, Kuzhuvelil B Harikumar, Kwang Seok Ahn, Vladimir Badmaev, Bharat B Aggarwa. Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis. Cancer research. vol 68. issue 21. 2008-12-08. PMID:18974130. |
suppression of these proteins enhanced apoptosis induced by tnf. |
2008-12-08 |
2023-08-12 |
Not clear |
| Jong-Hyun Kim, Chulhee Choi, Etty N Benveniste, Daeho Kwo. TRAIL induces MMP-9 expression via ERK activation in human astrocytoma cells. Biochemical and biophysical research communications. vol 377. issue 1. 2008-11-28. PMID:18834856. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is known as the death ligand, which induces preferential apoptosis of transformed tumor cells. |
2008-11-28 |
2023-08-12 |
human |