| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Theas, C Rival, S Jarazo-Dietrich, P Jacobo, V A Guazzone, L Lusti. Tumour necrosis factor-alpha released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis. Human reproduction (Oxford, England). vol 23. issue 8. 2008-09-29. PMID:18579514. |
based on the previous results showing that the number of macrophages and apoptotic gc expressing tumour necrosis factor (tnf) receptor 1 increased in eao, we studied the role of macrophages and tnf-alpha in gc apoptosis. |
2008-09-29 |
2023-08-12 |
rat |
| Marcus Lettau, Maren Paulsen, Dieter Kabelitz, Ottmar Jansse. Storage, expression and function of Fas ligand, the key death factor of immune cells. Current medicinal chemistry. vol 15. issue 17. 2008-09-26. PMID:18673218. |
the tnf family member fas ligand (fasl) induces apoptosis in fas-expressing cells and serves as a key death factor in the immune system. |
2008-09-26 |
2023-08-12 |
Not clear |
| Se Eun Byeon, Yong Gyu Lee, Jin-Chul Kim, Jae Gun Han, Hyeon Yong Lee, Jae Youl Ch. Hinokitiol, a natural tropolone derivative, inhibits TNF-alpha production in LPS-activated macrophages via suppression of NF-kappaB. Planta medica. vol 74. issue 8. 2008-09-17. PMID:18537078. |
in this study, we examined the modulatory effect of hinokitiol (hk) on the production of tumor necrosis factor (tnf)-alpha, a critical factor involved in skin inflammation and hair follicle apoptosis. |
2008-09-17 |
2023-08-12 |
Not clear |
| Toshimitsu Yamaoka, Fang Yan, Hanwei Cao, Stuart S Hobbs, Rebecca S Dise, Wei Tong, D Brent Pol. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18701712. |
tnf stimulated egfr phosphorylation in young adult mouse colon epithelial cells, and loss of egfr expression or inhibition of kinase activity increased tnf-induced apoptosis, which was prevented in wt but not by kinase-inactive egfr expression. |
2008-09-16 |
2023-08-12 |
mouse |
| Toshimitsu Yamaoka, Fang Yan, Hanwei Cao, Stuart S Hobbs, Rebecca S Dise, Wei Tong, D Brent Pol. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18701712. |
similarly, tnf injection stimulated apoptosis in egfr-kinase-defective mice (egfr(wa2)) compared with wt mice. |
2008-09-16 |
2023-08-12 |
mouse |
| Toshimitsu Yamaoka, Fang Yan, Hanwei Cao, Stuart S Hobbs, Rebecca S Dise, Wei Tong, D Brent Pol. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 33. 2008-09-16. PMID:18701712. |
tnf also activated erbb2, and loss of erbb2 expression increased tnf-induced apoptosis. |
2008-09-16 |
2023-08-12 |
mouse |
| Chandra Iyer, Astrid Kosters, Gautam Sethi, Ajaikumar B Kunnumakkara, Bharat B Aggarwal, James Versalovi. Probiotic Lactobacillus reuteri promotes TNF-induced apoptosis in human myeloid leukemia-derived cells by modulation of NF-kappaB and MAPK signalling. Cellular microbiology. vol 10. issue 7. 2008-09-09. PMID:18331465. |
l. reuteri secretes factors that potentiate apoptosis in myeloid leukemia-derived cells induced by tumour necrosis factor (tnf), as indicated by intracellular esterase activity, terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end-labelling assays and poly (adp-ribose) polymerase cleavage. |
2008-09-09 |
2023-08-12 |
human |
| Hajime Kin, Ning-Ping Wang, James Mykytenko, James Reeves, Jeremiah Deneve, Rong Jiang, Amanda J Zatta, Robert A Guyton, Jakob Vinten-Johansen, Zhi-Qing Zha. Inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa B translocation and TNF alpha release. Shock (Augusta, Ga.). vol 29. issue 6. 2008-09-09. PMID:18496137. |
inhibition of myocardial apoptosis by postconditioning is associated with attenuation of oxidative stress-mediated nuclear factor-kappa b translocation and tnf alpha release. |
2008-09-09 |
2023-08-12 |
rat |
| Jay R Radke, Zeba K Siddiqui, Tanya A Miura, John M Routes, James L Coo. E1A oncogene enhancement of caspase-2-mediated mitochondrial injury sensitizes cells to macrophage nitric oxide-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 12. 2008-09-05. PMID:18523293. |
the adenovirus e1a oncogene induces innate immune rejection of tumors by sensitizing tumor cells to apoptosis in response to injuries, such as those inflicted by macrophage-produced tnf alpha and no. |
2008-09-05 |
2023-08-12 |
mouse |
| Jay R Radke, Zeba K Siddiqui, Tanya A Miura, John M Routes, James L Coo. E1A oncogene enhancement of caspase-2-mediated mitochondrial injury sensitizes cells to macrophage nitric oxide-induced apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 180. issue 12. 2008-09-05. PMID:18523293. |
however, creation of e1a-positive nih-3t3 mouse cell variants with high-level, nf-kappab-dependent resistance to tnf did not coselect for resistance to apoptosis induced by either macrophage-no or chemical-no, as the hypothesis would predict. |
2008-09-05 |
2023-08-12 |
mouse |
| René Rodríguez, Victor M Campa, José Riera, M Teresa Carcedo, David S Ucker, Sofía Ramos, Pedro S Laz. TNF triggers mitogenic signals in NIH 3T3 cells but induces apoptosis when the cell cycle is blocked. European cytokine network. vol 18. issue 4. 2008-09-03. PMID:17993451. |
tnf triggers mitogenic signals in nih 3t3 cells but induces apoptosis when the cell cycle is blocked. |
2008-09-03 |
2023-08-12 |
Not clear |
| Chang-Huei Tsao, Hong-Lin Su, Yi-Ling Lin, Han-Pang Yu, Shu-Ming Kuo, Ching-I Shen, Ching-Wen Chen, Ching-Len Lia. Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner. The Journal of general virology. vol 89. issue Pt 8. 2008-09-02. PMID:18632964. |
interestingly, a fas-associated death-domain-containing protein (fadd) dominant-negative mutant, which interfered with transmission of the extracellular death signals into cells through the fas/tumour necrosis factor (tnf) receptor, failed to block jev-induced apoptosis and caspase-8 activation, implying that receptor oligomerization of the fas/tnf pathway might not participate in jev-induced apoptosis. |
2008-09-02 |
2023-08-12 |
mouse |
| Preetha Anand, Chitra Sundaram, Sonia Jhurani, Ajaikumar B Kunnumakkara, Bharat B Aggarwa. Curcumin and cancer: an "old-age" disease with an "age-old" solution. Cancer letters. vol 267. issue 1. 2008-08-27. PMID:18462866. |
curcumin is a diferuloylmethane derived from the indian spice, turmeric (popularly called "curry powder") that has been shown to interfere with multiple cell signaling pathways, including cell cycle (cyclin d1 and cyclin e), apoptosis (activation of caspases and down-regulation of antiapoptotic gene products), proliferation (her-2, egfr, and ap-1), survival (pi3k/akt pathway), invasion (mmp-9 and adhesion molecules), angiogenesis (vegf), metastasis (cxcr-4) and inflammation (nf-kappab, tnf, il-6, il-1, cox-2, and 5-lox). |
2008-08-27 |
2023-08-12 |
Not clear |
| Hidenari Nagai, Daisuke Miyaki, Teppei Matsui, Masahiro Kanayama, Katsuya Higami, Kouichi Momiyama, Takashi Ikehara, Manabu Watanabe, Yasukiyo Sumino, Kazumasa Mik. Changes of cytokines in cirrhosis patients with advanced hepatocellular carcinoma treated by intra-arterial chemotherapy. Cancer chemotherapy and pharmacology. vol 62. issue 2. 2008-08-26. PMID:17899083. |
tumor necrosis factor (tnf) induces cancer cell-specific apoptosis by binding to a tnf-related apoptosis-inducing ligand. |
2008-08-26 |
2023-08-12 |
Not clear |
| Linda C Burkly, Jennifer S Michaelson, Kyungmin Hahm, Aniela Jakubowski, Timothy S Zhen. TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine. vol 40. issue 1. 2008-08-26. PMID:17981048. |
first described as a weak apoptosis inducer, the tnf superfamily ligand tweak has since emerged as a cytokine that regulates multiple cellular responses, including proinflammatory activity, angiogenesis and cell proliferation, suggesting roles in inflammation and cancer. |
2008-08-26 |
2023-08-12 |
mouse |
| Boel De Paepe, Guy G Brusselle, Tania Maes, Kim K Creus, Sophie D'hose, Nele D'Haese, Ken R Bracke, An I D'hulst, Guy F Joos, Jan L De Bleecke. TNF alpha receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice. Acta neuropathologica. vol 115. issue 6. 2008-08-26. PMID:18309502. |
cs-induced apoptosis was observed in all genotypes, while a significant reduction of cross-sectional areas of myofibres was present only in tnf alpha r2ko mice. |
2008-08-26 |
2023-08-12 |
mouse |
| Boel De Paepe, Guy G Brusselle, Tania Maes, Kim K Creus, Sophie D'hose, Nele D'Haese, Ken R Bracke, An I D'hulst, Guy F Joos, Jan L De Bleecke. TNF alpha receptor genotype influences smoking-induced muscle-fibre-type shift and atrophy in mice. Acta neuropathologica. vol 115. issue 6. 2008-08-26. PMID:18309502. |
our data suggest that the skeletal muscle manifestations associated with this murine copd model are under complex regulation by both tnfalpha receptors, but that tnf alpha r2 may be the most important determinant for the outcome of cs-induced myofibre apoptosis. |
2008-08-26 |
2023-08-12 |
mouse |
| Benjamin D Cosgrove, Connie Cheng, Justin R Pritchard, Donna B Stolz, Douglas A Lauffenburger, Linda G Griffit. An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology (Baltimore, Md.). vol 48. issue 1. 2008-08-26. PMID:18536058. |
tumor necrosis factor-alpha (tnf) is an inflammatory cytokine that induces context-dependent proliferation, survival, and apoptosis responses in hepatocytes. |
2008-08-26 |
2023-08-12 |
rat |
| Benjamin D Cosgrove, Connie Cheng, Justin R Pritchard, Donna B Stolz, Douglas A Lauffenburger, Linda G Griffit. An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology (Baltimore, Md.). vol 48. issue 1. 2008-08-26. PMID:18536058. |
tnf stimulates and enhances growth factor-mediated hepatocyte proliferation and survival following partial hepatectomy, but also acts in concert with other inflammatory cytokines of the innate immune response during viral infection to induce apoptosis in hepatocytes. |
2008-08-26 |
2023-08-12 |
rat |
| Benjamin D Cosgrove, Connie Cheng, Justin R Pritchard, Donna B Stolz, Douglas A Lauffenburger, Linda G Griffit. An inducible autocrine cascade regulates rat hepatocyte proliferation and apoptosis responses to tumor necrosis factor-alpha. Hepatology (Baltimore, Md.). vol 48. issue 1. 2008-08-26. PMID:18536058. |
we show that tnf potently induces apoptosis of adenovirus-infected hepatocytes in a manner similarly determined through the integrated activity of a coupled tgf-alpha-il-1alpha/beta-il-1ra autocrine cascade. |
2008-08-26 |
2023-08-12 |
rat |