| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Krishnaraj Rajalingam, Manu Sharma, Christine Lohmann, Monique Oswald, Oliver Thieck, Christopher J Froelich, Thomas Rude. Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells. PloS one. vol 3. issue 9. 2008-11-25. PMID:18769617. |
consistently, interfering with mcl-1 up-regulation sensitized infected cells for apoptosis induced via the tnf receptor, dna damage, granzyme b and stress. |
2008-11-25 |
2023-08-12 |
human |
| b' Vladimir Jurisi\\xc4\\x87, Sladjana Stojaci\\xc4\\x87-Djeni\\xc4\\x87, Natasa Colovi\\xc4\\x87, Gordana Konjevi\\xc4\\x8. [The role of cytokine in regulation of the natural killer cell activity]. Srpski arhiv za celokupno lekarstvo. vol 136. issue 7-8. 2008-11-25. PMID:18959181.' |
we also describe that the release of cytokines and mediators show local or distance effects, or induce apoptosis (mostly by secreted tnf-alpha) after binding appropriated killer cell receptors from tnf receptor superfamily. |
2008-11-25 |
2023-08-12 |
Not clear |
| S Wan. The promise of cancer therapeutics targeting the TNF-related apoptosis-inducing ligand and TRAIL receptor pathway. Oncogene. vol 27. issue 48. 2008-11-14. PMID:18931688. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf superfamily and has been shown to induce apoptosis in cancer cells but not normal cells. |
2008-11-14 |
2023-08-12 |
human |
| Concetta Conticello, Luana Adamo, Luisa Vicari, Raffaella Giuffrida, Gioacchin Iannolo, Gabriele Anastasi, Laura Caruso, Gaetano Moschetti, Alessandra Cupri, Giuseppe Antonio Palumbo, Massimo Gulisano, Ruggero De Maria, Rosario Giustolisi, Francesco Di Raimond. Antitumor activity of bortezomib alone and in combination with TRAIL in human acute myeloid leukemia. Acta haematologica. vol 120. issue 1. 2008-11-12. PMID:18716397. |
here we examined the sensitivity of bone marrow cells from aml patients (34 patients: 25 newly diagnosed, 4 relapsed, 5 refractory) to bortezomib alone or in combination with trail, a member of the tnf family that induces apoptosis in tumor cells while sparing normal cells. |
2008-11-12 |
2023-08-12 |
human |
| Min Zhan, Fang Yuan, Hua Liu, Hui Chen, Xingbiao Qiu, Weiyi Fan. Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin. Acta biochimica et biophysica Sinica. vol 40. issue 9. 2008-11-12. PMID:18776988. |
to evaluate the possible role of ghrelin in the development of atherosclerosis, its effects on tumor necrosis factor (tnf)-alpha-induced proliferation and apoptosis of vascular smooth muscle cells (vsmcs) were investigated. |
2008-11-12 |
2023-08-12 |
rat |
| Ajaikumar B Kunnumakkara, Haruyo Ichikawa, Preetha Anand, Chiramel J Mohankumar, Padmanabhan S Hema, Mangalam S Nair, Bharat B Aggarwa. Coronarin D, a labdane diterpene, inhibits both constitutive and inducible nuclear factor-kappa B pathway activation, leading to potentiation of apoptosis, inhibition of invasion, and suppression of osteoclastogenesis. Molecular cancer therapeutics. vol 7. issue 10. 2008-11-12. PMID:18852134. |
suppression of these gene products by the diterpene enhanced apoptosis induced by tnf and chemotherapeutic agents, suppressed tnf-induced cellular invasion, and abrogated receptor activator of nf-kappab ligand-induced osteoclastogenesis. |
2008-11-12 |
2023-08-12 |
Not clear |
| Dharmalingam Subramaniam, Periyasamy Giridharan, Nabendu Murmu, Nallakandy P Shankaranarayanan, Randal May, Courtney W Houchen, Rama P Ramanujam, Arun Balakrishnan, Ram A Vishwakarma, Shrikant Anan. Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos. Cancer research. vol 68. issue 20. 2008-11-07. PMID:18922933. |
we have identified a natural compound that activates apoptosis of epithelial cancer cells through activation of tumor necrosis factor-alpha (tnf-alpha), tnf receptor (tnfr)-associated death domain (tradd), and caspases. |
2008-11-07 |
2023-08-12 |
Not clear |
| J Zhang, Q Wang, N Zhu, M Yu, B Shen, J Xiang, A Li. Cyclic AMP inhibits JNK activation by CREB-mediated induction of c-FLIP(L) and MKP-1, thereby antagonizing UV-induced apoptosis. Cell death and differentiation. vol 15. issue 10. 2008-10-27. PMID:18566605. |
our previous study has shown that camp, by protein kinase a (pka)-camp response element-binding protein (creb)-dynein light chain (dlc) pathway, negatively regulates mitogen-activated protein kinase p38 activation, thereby contributing to tumor necrosis factor (tnf)-alpha-induced apoptosis in certain types of cells. |
2008-10-27 |
2023-08-12 |
Not clear |
| Guangwu Xu, Yingyu Zhang, Liying Zhang, Guangwen Ren, Yufang Sh. Bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of IFNgamma and TNF by producing nitric oxide. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18755151. |
bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of ifngamma and tnf by producing nitric oxide. |
2008-10-27 |
2023-08-12 |
mouse |
| Guangwu Xu, Yingyu Zhang, Liying Zhang, Guangwen Ren, Yufang Sh. Bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of IFNgamma and TNF by producing nitric oxide. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18755151. |
however, in the present study, we found that bmscs induced apoptosis of lymphoma cells in the presence of infgamma and tnf. |
2008-10-27 |
2023-08-12 |
mouse |
| Guangwu Xu, Yingyu Zhang, Liying Zhang, Guangwen Ren, Yufang Sh. Bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of IFNgamma and TNF by producing nitric oxide. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18755151. |
ifngamma and tnf dramatically induced the expression of inducible nitric oxide synthase (inos) by bmscs in culture, and bmscs generated from inos knockout mice did not induce apoptosis of lymphoma cells in the presence of ifngamma and tnf. |
2008-10-27 |
2023-08-12 |
mouse |
| Guangwu Xu, Yingyu Zhang, Liying Zhang, Guangwen Ren, Yufang Sh. Bone marrow stromal cells induce apoptosis of lymphoma cells in the presence of IFNgamma and TNF by producing nitric oxide. Biochemical and biophysical research communications. vol 375. issue 4. 2008-10-27. PMID:18755151. |
taken together, our findings indicate that bmscs induce apoptosis of lymphoma cells in the presence of ifngamma and tnf, and that the proapoptotic effect of bmscs is mediated by nitric oxide. |
2008-10-27 |
2023-08-12 |
mouse |
| Masami Ishibashi, Takashi Ohtsuk. Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis. Medicinal research reviews. vol 28. issue 5. 2008-10-14. PMID:18273883. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces apoptosis in many transformed cells but not in normal cells and, hence, has been expected as a new anticancer strategy. |
2008-10-14 |
2023-08-12 |
Not clear |
| Seigo Suzuki, Akihiro Naito, Takayuki Asano, Teresa T Evans, Shrikanth A G Reddy, Masahiro Higuch. Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a. Cancer letters. vol 268. issue 1. 2008-10-14. PMID:18468786. |
tnf plus protein synthesis inhibitor cycloheximide-induced apoptosis in human myelogenous leukemia ml-1a but not in c19, respiration minus mitochondrial dna-deficient c19 cells, derived from ml-1a. |
2008-10-14 |
2023-08-12 |
human |
| Seigo Suzuki, Akihiro Naito, Takayuki Asano, Teresa T Evans, Shrikanth A G Reddy, Masahiro Higuch. Constitutive activation of AKT pathway inhibits TNF-induced apoptosis in mitochondrial DNA-deficient human myelogenous leukemia ML-1a. Cancer letters. vol 268. issue 1. 2008-10-14. PMID:18468786. |
treatment of c19 with ly294002, which inhibits pi-3 kinase and inhibits akt, significantly increased apoptosis induction by tnf plus cycloheximide and eliminated phosphorylation of akt. |
2008-10-14 |
2023-08-12 |
human |
| Monimoy Banerjee, Chengdong Huang, Javier Marquez, Smita Mohant. Probing the structure and function of human glutaminase-interacting protein: a possible target for drug design. Biochemistry. vol 47. issue 35. 2008-10-09. PMID:18690705. |
this is the first report of gip recognition of the cell surface protein fas, which belongs to the tumor necrosis factor (tnf) receptor family and mediates cell apoptosis. |
2008-10-09 |
2023-08-12 |
human |
| Peter Magee, Stephen Pearson, Jeremy Alle. The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation. Lipids in health and disease. vol 7. 2008-10-06. PMID:18638380. |
it is also reported that pathologic levels of the pro-inflammatory cytokine tumour necrosis factor (tnf)-alpha are associated with muscle wasting, exerted through inhibition of myogenic differentiation and enhanced apoptosis. |
2008-10-06 |
2023-08-12 |
Not clear |
| Fangling Xu, Xiaodong Liang, Robert B Tesh, Shu-Yuan Xia. Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injury. The Journal of general virology. vol 89. issue Pt 9. 2008-09-30. PMID:18753227. |
the effects of caspase inhibitors (caspis) and tnf on cellular viability, virus replication, and morphological and biochemical changes in apoptosis were examined in hepg2 cells at different time points after infection with ptv (adames strain). |
2008-09-30 |
2023-08-12 |
Not clear |
| Fangling Xu, Xiaodong Liang, Robert B Tesh, Shu-Yuan Xia. Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injury. The Journal of general virology. vol 89. issue Pt 9. 2008-09-30. PMID:18753227. |
tnf treatment further decreased cellular viability after ptv infection and increased the level of apoptosis, whilst caspis partially inhibited these effects. |
2008-09-30 |
2023-08-12 |
Not clear |
| Fangling Xu, Xiaodong Liang, Robert B Tesh, Shu-Yuan Xia. Characterization of cell-death pathways in Punta Toro virus-induced hepatocyte injury. The Journal of general virology. vol 89. issue Pt 9. 2008-09-30. PMID:18753227. |
these findings indicate that tnf, caspase-8 and caspase-9 contribute to ptv-induced hepatocytic apoptosis and that additional mediators are probably also involved in this process. |
2008-09-30 |
2023-08-12 |
Not clear |