| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Shankar, U Sivaprasad, A Bas. Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53. Oncogene. vol 27. issue 28. 2008-07-23. PMID:18317451. |
protein kinase c epsilon (pkc epsilon ) acts as an antiapoptotic protein and inhibits tumor necrosis factor-alpha (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis in mcf-7 breast cancer cells. |
2008-07-23 |
2023-08-12 |
human |
| E Shankar, U Sivaprasad, A Bas. Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53. Oncogene. vol 27. issue 28. 2008-07-23. PMID:18317451. |
members of the tnf receptor superfamily trigger apoptosis independent of the tumor suppressor protein p53, which primarily affects dna damage-induced apoptosis. |
2008-07-23 |
2023-08-12 |
human |
| Keiichiro Nakamura, Norio Takamoto, Atsushi Hongo, Junichi Kodama, Fernando Abrzua, Yasutomo Nasu, Hiromi Kumon, Yuji Hiramats. Secretory leukoprotease inhibitor inhibits cell growth through apoptotic pathway on ovarian cancer. Oncology reports. vol 19. issue 5. 2008-07-22. PMID:18425362. |
slpi showed potential therapeutic inhibitory effects mediated by tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), tnf-alpha, death receptor (dr)-4, dr-5 and tnf receptor (tnfr)-i expression which lead to an activation of apoptosis pathway through caspase-2, caspase-8 and caspase-9. |
2008-07-22 |
2023-08-12 |
Not clear |
| Jing Wang, Zhou Lin, Chun Xia Qiao, Ming Lv, Ming Yu, He Xiao, Qingyang Wang, Liyan Wang, Jiannan Feng, Beifen Shen, Yuanfang Ma, Yan L. Characterization of a novel anti-DR5 monoclonal antibody WD1 with the potential to induce tumor cell apoptosis. Cellular & molecular immunology. vol 5. issue 1. 2008-07-15. PMID:18318995. |
tnf-related apoptosis-inducing ligand (trail) is a tnf family member capable of inducing apoptosis. |
2008-07-15 |
2023-08-12 |
mouse |
| Yuki Saito, Minoru Hasegawa, Manabu Fujimoto, Takashi Matsushita, Mayuka Horikawa, Motoi Takenaka, Fumihide Ogawa, Junko Sugama, Douglas A Steeber, Shinichi Sato, Kazuhiko Takehar. The loss of MCP-1 attenuates cutaneous ischemia-reperfusion injury in a mouse model of pressure ulcer. The Journal of investigative dermatology. vol 128. issue 7. 2008-06-24. PMID:18219277. |
mcp-1(-/-) mice showed reduced macrophage infiltration and expression of tumor-necrosis factor-alpha (tnf)-alpha and inos during ir cycles leading to attenuated apoptosis and skin injury. |
2008-06-24 |
2023-08-12 |
mouse |
| M-C Park, S J Chung, S-J Jung, Y-B Park, S-K Le. Relationship of serum TWEAK level to cytokine level, disease activity, and response to anti-TNF treatment in patients with rheumatoid arthritis. Scandinavian journal of rheumatology. vol 37. issue 3. 2008-06-24. PMID:18465450. |
to determine the serum concentration of tumour necrosis factor (tnf)-related weak inducer of apoptosis (tweak) in patients with rheumatoid arthritis (ra) and to investigate the relationship between tweak level and disease activity, proinflammatory cytokine levels, and response to anti-tnf treatment. |
2008-06-24 |
2023-08-12 |
Not clear |
| Luiz E Henkes, Brian T Sullivan, Maureen P Lynch, Richard Kolesnick, Danielle Arsenault, Mark Puder, John S Davis, Bo R Rued. Acid sphingomyelinase involvement in tumor necrosis factor alpha-regulated vascular and steroid disruption during luteolysis in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 22. 2008-06-24. PMID:18505843. |
tnf also is implicated in the regulation of reproduction by its actions to affect ovarian steroidogenic cells and to induce apoptosis of corpus luteum (cl)-derived endothelial cells in vitro. |
2008-06-24 |
2023-08-12 |
mouse |
| Vassiliki Pelekanou, Marilena Kampa, Maria Kafousi, Katerina Darivianaki, Elias Sanidas, Dimitrios D Tsiftsis, Efstathios N Stathopoulos, Andreas Tsapis, Elias Castana. Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. BMC cancer. vol 8. 2008-06-12. PMID:18366696. |
tumor necrosis factor (tnf) family members (19 ligands and 29 receptors) represent a pleiotropic family of agents, related to a plethora of cellular events from proliferation and differentiation to apoptosis and tumor reduction. |
2008-06-12 |
2023-08-12 |
Not clear |
| Makoto Sumikoshi, Koichi Hashimoto, Yukihiko Kawasaki, Hiroko Sakuma, Tatsuo Suzutani, Hitoshi Suzuki, Mitsuaki Hosoy. Human influenza virus infection and apoptosis induction in human vascular endothelial cells. Journal of medical virology. vol 80. issue 6. 2008-06-12. PMID:18428129. |
acute encephalopathy accompanying influenza virus infection results in brain and systemic organ failure mainly through vasogenic edema with high levels of inflammatory cytokines, such as blood tumor necrosis factor (tnf)-alpha and interleukin (il)-6, as well as the cytochrome c apoptosis marker. |
2008-06-12 |
2023-08-12 |
human |
| Momoko Takahashi, Hironobu Yasui, Aki Ogura, Taketoshi Asanuma, Nobuo Kubota, Michihiko Tsujitani, Mikinori Kuwabara, Osamu Inanam. X irradiation combined with TNF alpha-related apoptosis-inducing ligand (TRAIL) reduces hypoxic regions of human gastric adenocarcinoma xenografts in SCID mice. Journal of radiation research. vol 49. issue 2. 2008-06-10. PMID:18227621. |
x irradiation combined with tnf alpha-related apoptosis-inducing ligand (trail), which is the ligand of dr5, induced apoptosis in vitro (takahashi et al., (2007) journal of radiation research, 48: 461-468). |
2008-06-10 |
2023-08-12 |
mouse |
| Parth B Amin, Lawrence N Diebel, David M Liberat. The synergistic effect of ethanol and shock insults on Caco-2 cytokine production and apoptosis. Shock (Augusta, Ga.). vol 29. issue 5. 2008-06-09. PMID:18414237. |
lastly, the findings in apoptosis mirror the data of the tnf production in the apical compartment. |
2008-06-09 |
2023-08-12 |
Not clear |
| Cynthia L Bethea, Arubala P Redd. Effect of ovarian hormones on survival genes in laser captured serotonin neurons from macaques. Journal of neurochemistry. vol 105. issue 4. 2008-06-06. PMID:18182058. |
twofold or greater decreases occurred in tnf receptor interacting serine-threonine kinase 1 (rip1), bh3 interacting domain death agonist (bid), apoptotic peptidase activating factor 1 (apaf1), caspase recruitment domain 8 (card8), apoptosis inducing factor (aif), diablo and cyclins a, b, d, and e. the regulation of sod1, calpain 2, diablo, and cyclin d was confirmed with quantitative rt-pcr (n = 3/treatment). |
2008-06-06 |
2023-08-12 |
monkey |
| Men-Luh Yen, Hwei-Fang Tsai, Yi-Ying Wu, Hsiao-Lin Hwa, Be-Hang Lee, Ping-Ning Hs. TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation from monocyte/macrophage lineage precursor cells. Molecular immunology. vol 45. issue 8. 2008-06-05. PMID:18206242. |
recent evidence indicates that the tnf-related apoptosis-inducing ligand (trail) of the tnf ligand superfamily, which was initially thought to induce apoptosis in many transformed cell lines, can serve as an effector molecule in activated t cells. |
2008-06-05 |
2023-08-12 |
human |
| Ivana Stanic, Silvia Cetrullo, Annalisa Facchini, Claudio Stefanelli, Rosa Maria Borzì, Benedetta Tantini, Carlo Guarnieri, Claudio Marcello Caldarera, Flavio Flamign. Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes. Journal of cellular physiology. vol 216. issue 1. 2008-06-04. PMID:18231987. |
in conclusion, following denspm treatment, c-28/i2 chondrocytes are initially sensitized to caspase 9-dependent apoptosis in the presence of tnf and chx and may eventually undergo a late and mainly caspase-independent cell death in the absence of other stimuli. |
2008-06-04 |
2023-08-12 |
human |
| Mark Grossetete, Gary A Rosenber. Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 28. issue 4. 2008-06-03. PMID:17971790. |
tissue inhibitor of metalloproteinase-3 promotes neuronal apoptosis in vitro by blocking the shedding of the tumor necrosis factor (tnf) superfamily of death receptors/ligands by stromelysin-1 (mmp-3). |
2008-06-03 |
2023-08-12 |
mouse |
| Mark Grossetete, Gary A Rosenber. Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 28. issue 4. 2008-06-03. PMID:17971790. |
our results fail to implicate timp-3 in apoptosis in cih, but show that bb-94 increased apoptosis in cih, possibly by blocking shedding of tnf death receptors and/or their ligands. |
2008-06-03 |
2023-08-12 |
mouse |
| Marc Tarrus, Almer M van der Sloot, Kai Temming, Marie Lacombe, Frank Opdam, Wim J Quax, Grietje Molema, Klaas Poelstra, Robbert J Ko. RGD-avidin-biotin pretargeting to alpha v beta 3 integrin enhances the proapoptotic activity of TNF alpha related apoptosis inducing ligand (TRAIL). Apoptosis : an international journal on programmed cell death. vol 13. issue 2. 2008-06-03. PMID:18071905. |
rgd-avidin-biotin pretargeting to alpha v beta 3 integrin enhances the proapoptotic activity of tnf alpha related apoptosis inducing ligand (trail). |
2008-06-03 |
2023-08-12 |
Not clear |
| Barbara Zahorska-Markiewicz, Magdalena Olszanecka-Glinianowicz, Joanna Janowska, Piotr Koceła. The effect of weight loss on serum concentrations of FAS and tumour necrosis factor alpha in obese women. Endokrynologia Polska. vol 59. issue 1. 2008-06-03. PMID:18335396. |
the suprafamily of tumour necrosis factor (tnf) receptors stimulate apoptosis. |
2008-06-03 |
2023-08-12 |
human |
| Gen-Hong Yao, Li-Jun Ling, Jian-Feng Luan, Dong Ye, Pei-Yuan Zhu, Qian-Hong Le. Induction of apoptosis by recombinant soluble human TRAIL in Jurkat cells. Biomedical and environmental sciences : BES. vol 20. issue 6. 2008-06-03. PMID:18348405. |
to investigate the therapeutic potential of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), a member of the tnf superfamily, and to analyze trail-induced apoptosis in jurkat cells. |
2008-06-03 |
2023-08-12 |
human |
| Yang Zai-Xing, Liang Yan, Wang Hao, Zhu Ye, Li Chang, Zhong Ren-Qia. Preliminary clinical measurement of the expression of TNF-related apoptosis inducing ligand in patients with ankylosing spondylitis. Journal of clinical laboratory analysis. vol 22. issue 2. 2008-05-30. PMID:18348311. |
it has recently been reported that tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) plays various roles in such autoimmune diseases as diabetes, multiple sclerosis (ms), and systemic lupus erythematosus (sle). |
2008-05-30 |
2023-08-12 |
human |