| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amit Asija, Stephen J Peterson, David E Stec, Nader G Abraha. Targeting endothelial cells with heme oxygenase-1 gene using VE-cadherin promoter attenuates hyperglycemia-mediated cell injury and apoptosis. Antioxidants & redox signaling. vol 9. issue 12. 2008-01-25. PMID:17883332. |
risk factors for cardiovascular diseases include hyperglycemia, tnf, and reactive oxygen species (ros), which collectively contribute to vascular endothelial cell dysfunction and apoptosis. |
2008-01-25 |
2023-08-12 |
human |
| A Avramidou, C Kroczek, C Lang, W Schuh, H-M Jäck, D Mielen. The novel adaptor protein Swiprosin-1 enhances BCR signals and contributes to BCR-induced apoptosis. Cell death and differentiation. vol 14. issue 11. 2008-01-22. PMID:17673920. |
swiprosin-1-enhanced apoptosis was blocked through nuclear factor kappab-activating stimuli, namely b-cell-activating factor of the tnf family, anti-cd40 and lipopolysaccharide (lps). |
2008-01-22 |
2023-08-12 |
Not clear |
| Jiangguo Zhang, Gaosi X. Suppression of FasL expression in tumor cells and preventing tumor necrosis factor-induced apoptosis by adenovirus 14.7K is an effective escape mechanism for immune cells. Cancer genetics and cytogenetics. vol 179. issue 2. 2008-01-22. PMID:18036397. |
to elucidate if the fas/fasl signal pathway participates in the immune escape of tumor cells, and if contemporary fas/fasl and tumor necrosis factor (tnf))-induced apoptosis is better for immune cell survival than just blocking fas/fasl-induced apoptotic signal. |
2008-01-22 |
2023-08-12 |
mouse |
| Malú G Tansey, Melissa K McCoy, Tamy C Frank-Canno. Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention. Experimental neurology. vol 208. issue 1. 2008-01-17. PMID:17720159. |
cellular mechanisms activated or enhanced by inflammatory processes that may contribute to mitochondrial dysfunction, oxidative stress, or apoptosis of dopaminergic (da) neurons will be reviewed, with special emphasis on tumor necrosis factor (tnf) and interleukin-1-beta (il-1beta) signaling pathways. |
2008-01-17 |
2023-08-12 |
Not clear |
| M Filippova, T A Brown-Bryan, C A Casiano, P J Duerksen-Hughe. The human papillomavirus 16 E6 protein can either protect or further sensitize cells to TNF: effect of dose. Cell death and differentiation. vol 12. issue 12. 2008-01-11. PMID:15933739. |
intriguingly, clones with a high level of e6 expression displayed an increased sensitivity to tnf by undergoing apoptosis, while those with low expression were resistant. |
2008-01-11 |
2023-08-12 |
human |
| Manoj K Pandey, Bokyung Sung, Kwang Seok Ahn, Ajaikumar B Kunnumakkara, Madan M Chaturvedi, Bharat B Aggarwa. Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway. Blood. vol 110. issue 10. 2008-01-09. PMID:17673602. |
treatment of cells with ga enhanced apoptosis induced by tumor necrosis factor (tnf) and chemotherapeutic agents, inhibited the expression of gene products involved in antiapoptosis (iap1 and iap2, bcl-2, bcl-x(l), and traf1), proliferation (cyclin d1 and c-myc), invasion (cox-2 and mmp-9), and angiogenesis (vegf), all of which are known to be regulated by nf-kappab. |
2008-01-09 |
2023-08-12 |
human |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
tnf pretreatment interferes with mitochondrial apoptosis in the mouse liver by a20-mediated down-regulation of bax. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
pretreatment with low doses of the proinflammatory cytokine tnf has been shown to prevent hepatocellular apoptosis and liver damage in inflammatory as well as in ischemia/reperfusion-induced liver injury. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
our results show that pretreatment with tnf, or application of small-interfering rna directed against the proapoptotic bcl2 family member bax, interfered with the onset of mitochondrial apoptosis in vivo. |
2007-12-27 |
2023-08-12 |
mouse |
| Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel, Gisa Tieg. TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 10. 2007-12-27. PMID:17982095. |
the underlying mechanism of protection seems to involve a cascade of events, where tnf induces the expression of a20 in hepatocytes, a20 down-modulates bax expression by interference with transcriptional activation, and the reduced availability of bax interferes with the onset of mitochondrial apoptosis and the ensuing apoptotic liver damage. |
2007-12-27 |
2023-08-12 |
mouse |
| J A Kummer, O Micheau, P Schneider, N Bovenschen, R Broekhuizen, R Quadir, M C M Strik, C E Hack, J Tschop. Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis. Cell death and differentiation. vol 14. issue 8. 2007-12-20. PMID:17479112. |
apoptosis can be induced via a subgroup of the tumor necrosis factor (tnf) receptor superfamily, which recruit and activate pro-caspase-8 and -10. |
2007-12-20 |
2023-08-12 |
human |
| Karine Oumouna-Benachour, Mustapha Oumouna, Mourad Zerfaoui, Chetan Hans, Kenneth Fallon, A Hamid Boulare. Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis. Molecular carcinogenesis. vol 46. issue 12. 2007-12-20. PMID:17538954. |
after establishing a new method for isolating primary colon epithelial cells, we determined that cells derived from a/j mice were substantially more resistant to apoptosis in response to dimethylhydrazine or to a combination of tnf, cyclohexamide, and butyrate compared to cells from akr/j mice. |
2007-12-20 |
2023-08-12 |
mouse |
| Bayan T Takizawa, Edward M Uchio, Justin J Cohen, Marcia A Wheeler, Robert M Weis. Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer investigation. vol 25. issue 8. 2007-12-20. PMID:18058462. |
microarray analysis of apoptosis genes showed that levels of 14/114 gene products were decreased after 72 hours treatment with survivin sirna, including survivin, three tnf receptors, akt, c-abl, caspases and their related genes and bcl-2 and nf-kappab signaling related genes. |
2007-12-20 |
2023-08-12 |
Not clear |
| Bayan T Takizawa, Edward M Uchio, Justin J Cohen, Marcia A Wheeler, Robert M Weis. Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer investigation. vol 25. issue 8. 2007-12-20. PMID:18058462. |
downregulation of survivin causes changes in mitosis and apoptosis, which may be related to changes in tnf receptors and nf-kappab signaling. |
2007-12-20 |
2023-08-12 |
Not clear |
| Donna Amrán, Yolanda Sánchez, Carlos Fernández, Adrián M Ramos, Elena de Blas, Jacqueline Bréard, Consuelo Calle, Patricio Alle. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways. Biochimica et biophysica acta. vol 1773. issue 11. 2007-12-19. PMID:17673311. |
as(2)o(3) plus tnfalpha increases tnf receptor type 1 (tnf-r1) expression, decreases c-flip(l) expression, and causes caspase-8 and bid activation, and apoptosis is reduced by anti-tnf-r1 neutralizing antibody and caspase-8 inhibitor. |
2007-12-19 |
2023-08-12 |
human |
| E Zeldich, R Koren, M Dard, C Nemcovsky, M Weinre. Enamel matrix derivative protects human gingival fibroblasts from TNF-induced apoptosis by inhibiting caspase activation. Journal of cellular physiology. vol 213. issue 3. 2007-12-14. PMID:17607712. |
tnf induced classical signs of apoptosis in hgfs, including typical cellular morphology and increased caspase activity. |
2007-12-14 |
2023-08-12 |
human |
| Giorgio Zauli, Erika Rimondi, Susanna Stea, Fabio Baruffaldi, Marco Stebel, Carlotta Zerbinati, Federica Corallini, Paola Secchier. TRAIL inhibits osteoclastic differentiation by counteracting RANKL-dependent p27Kip1 accumulation in pre-osteoclast precursors. Journal of cellular physiology. vol 214. issue 1. 2007-12-14. PMID:17620297. |
experimental evidences indicate that the tnf family member tnf-related apoptosis inducing ligand (trail) might be involved in modulating osteoclastic differentiation. |
2007-12-14 |
2023-08-12 |
mouse |
| Kwang Seok Ahn, Xing Gong, Gautam Sethi, Madan M Chaturvedi, Anil K Jaiswal, Bharat B Aggarwa. Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. Cancer research. vol 67. issue 20. 2007-12-12. PMID:17942934. |
deficiency of nrh:quinone oxidoreductase 2 differentially regulates tnf signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. |
2007-12-12 |
2023-08-12 |
mouse |
| Kwang Seok Ahn, Xing Gong, Gautam Sethi, Madan M Chaturvedi, Anil K Jaiswal, Bharat B Aggarwa. Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. Cancer research. vol 67. issue 20. 2007-12-12. PMID:17942934. |
overall, our results indicate that deletion of nqo2 plays a differential role in tnf signaling pathway: by suppressing cell survival signals and potentiating tnf-induced apoptosis. |
2007-12-12 |
2023-08-12 |
mouse |
| M Martinez-Losa, J Cortijo, G Juan, M Ramón, M J Sanz, E J Morcill. Modulatory effects of N-acetyl-L-cysteine on human eosinophil apoptosis. The European respiratory journal. vol 30. issue 3. 2007-12-10. PMID:17504796. |
nac (5 mm) also increased the rate of apoptosis in the presence of tumour necrosis factor (tnf)-alpha (10 ng.ml(-1)) and interleukin-5 (5 ng.ml(-1)). |
2007-12-10 |
2023-08-12 |
human |