| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Zhong, Brad Gilbertson, Christina Cheer. Apoptosis of CD4+ and CD8+ T cells during experimental infection with Mycobacterium avium is controlled by Fas/FasL and Bcl-2-sensitive pathways, respectively. Immunology and cell biology. vol 81. issue 6. 2007-12-07. PMID:14636245. |
conversely, over-expression of b-cell lymphoma-2 (bcl-2), which is known to protect t cells from apoptosis signalled through the tnf receptor or due to the withdrawal of cytokines, totally protected cd8+ t cells from infected mice but had no effect on cd4+. |
2007-12-07 |
2023-08-12 |
mouse |
| Anju Singh, M Sures. A role for TNF in limiting the duration of CTL effector phase and magnitude of CD8 T cell memory. Journal of leukocyte biology. vol 82. issue 5. 2007-12-06. PMID:17704295. |
instead, we demonstrate that tnf limits the duration of the effector phase of the cd8 t cell response by regulating apoptosis and not proliferation of effector cells in vivo. |
2007-12-06 |
2023-08-12 |
mouse |
| Anju Singh, M Sures. A role for TNF in limiting the duration of CTL effector phase and magnitude of CD8 T cell memory. Journal of leukocyte biology. vol 82. issue 5. 2007-12-06. PMID:17704295. |
we further show that attenuation of effector cell apoptosis induced by tnf deficiency led to a substantial increase in the number of virus-specific memory cd8 t cells without affecting their function. |
2007-12-06 |
2023-08-12 |
mouse |
| Martin V Richter, David J Topha. The alpha1beta1 integrin and TNF receptor II protect airway CD8+ effector T cells from apoptosis during influenza infection. Journal of immunology (Baltimore, Md. : 1950). vol 179. issue 8. 2007-11-30. PMID:17911590. |
the alpha1beta1 integrin and tnf receptor ii protect airway cd8+ effector t cells from apoptosis during influenza infection. |
2007-11-30 |
2023-08-12 |
Not clear |
| Jae-Won Seol, Atul A Chaudhari, You-Jin Lee, Hyung-Sub Kang, In-Shik Kim, Nam-Soo Kim, Jin-Ho Park, Tae-Hyung Kim, Dai-Wu Seol, Sang-Youel Par. Regulation of DR-5 protein and mitochondrial transmembrane potential by gemcitabine, a possible mechanism of gemcitabine-enhanced TRAIL-induced apoptosis. Oncology reports. vol 18. issue 3. 2007-11-28. PMID:17671697. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf family and a potent inducer of apoptosis. |
2007-11-28 |
2023-08-12 |
Not clear |
| T Mustafa, H G Wiker, O Mørkve, L Svilan. Reduced apoptosis and increased inflammatory cytokines in granulomas caused by tuberculous compared to non-tuberculous mycobacteria: role of MPT64 antigen in apoptosis and immune response. Clinical and experimental immunology. vol 150. issue 1. 2007-11-08. PMID:17711491. |
in this study we investigated differences in apoptosis and immune response and their correlation with the expression of mycobacterium tuberculosis complex-specific secretory protein mpt64 in lesions caused by tuberculous or non-tuberculous mycobacteria by analysing the in situ expression of apoptosis-related proteins (fasl, fas, bax, bcl-2), apoptotic cells, inflammatory cytokines [tumour necrosis factor (tnf)-alpha, interleukin (il)-10, transforming growth factor (tgf)-beta, interferon (ifn)-gamma] and mpt64 antigen. |
2007-11-08 |
2023-08-12 |
Not clear |
| XiaoDong Huang, Anja Masselli, Steven M Frisch, Irina C Hunton, Yong Jiang, Jean Y J Wan. Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb. The Journal of biological chemistry. vol 282. issue 40. 2007-11-07. PMID:17686781. |
tumor necrosis factor-alpha (tnf) activates caspase-8 to cleave effector caspases or bid, resulting in type-1 or type-2 apoptosis, respectively. |
2007-11-07 |
2023-08-12 |
mouse |
| Kwang Seok Ahn, Gautam Sethi, Ta-Hsiang Chao, Saskia T C Neuteboom, Madan M Chaturvedi, Michael A Palladino, Anas Younes, Bharat B Aggarwa. Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products. Blood. vol 110. issue 7. 2007-11-06. PMID:17609425. |
here we demonstrate that salinosporamide a potentiated the apoptosis induced by tumor necrosis factor alpha (tnf), bortezomib, and thalidomide, and this correlated with down-regulation of gene products that mediate cell proliferation (cyclin d1, cyclooxygenase-2 [cox-2], and c-myc), cell survival (bcl-2, bcl-xl, cflip, traf1, iap1, iap2, and survivin), invasion (matrix metallopro-teinase-9 [mmp-9] and icam-1), and angiogenesis (vascular endothelial growth factor [vegf]). |
2007-11-06 |
2023-08-12 |
Not clear |
| Suntaek Hong, Chan Lee, Seong-Jin Ki. Smad7 sensitizes tumor necrosis factor induced apoptosis through the inhibition of antiapoptotic gene expression by suppressing activation of the nuclear factor-kappaB pathway. Cancer research. vol 67. issue 19. 2007-10-31. PMID:17909069. |
although tumor necrosis factor (tnf) induces apoptosis and cell death in many tumor cells, some cancer cells are still resistant to the tnf-induced death signal. |
2007-10-31 |
2023-08-12 |
human |
| Silvia Colucci, Giacomina Brunetti, Francesco Paolo Cantatore, Angela Oranger, Giorgio Mori, Paolo Pignataro, Roberto Tamma, Felice Roberto Grassi, Alberta Zallone, Maria Gran. The death receptor DR5 is involved in TRAIL-mediated human osteoclast apoptosis. Apoptosis : an international journal on programmed cell death. vol 12. issue 9. 2007-10-26. PMID:17558561. |
tnf-related apoptosis-inducing ligand (trail), a member of the tnf superfamily, induces apoptosis by interacting with its death receptors, (dr4, dr5). |
2007-10-26 |
2023-08-12 |
human |
| Sandra B Haudek, George E Taffet, Michael D Schneider, Douglas L Man. TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. The Journal of clinical investigation. vol 117. issue 9. 2007-10-23. PMID:17694177. |
tnf provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. |
2007-10-23 |
2023-08-12 |
mouse |
| Sandra B Haudek, George E Taffet, Michael D Schneider, Douglas L Man. TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. The Journal of clinical investigation. vol 117. issue 9. 2007-10-23. PMID:17694177. |
transgenic mice with cardiac-restricted overexpression of secretable tnf (mhcstnf) develop progressive lv wall thinning and dilation accompanied by an increase in cardiomyocyte apoptosis and a progressive loss of cytoprotective bcl-2. |
2007-10-23 |
2023-08-12 |
mouse |
| Yue-juan Qin, Zhen-lin Zhang, Lu-yang Yu, Jin-wei He, Ya-nan Hou, Tian-jin Liu, Jia-cai Wu, Song-hua Wu, Li-he Gu. A20 overexpression under control of mouse osteocalcin promoter in MC3T3-E1 cells inhibited tumor necrosis factor-alpha-induced apoptosis. Acta pharmacologica Sinica. vol 27. issue 9. 2007-10-19. PMID:16923345. |
to construct an a20 expression vector under the control of mouse osteocalcin promoter (oc-a20), and investigate osteoblastic mc3t3-e1 cell line, which stably overexpresses a20 protein prevented tumor necrosis factor (tnf)-alpha-induced apoptosis. |
2007-10-19 |
2023-08-12 |
mouse |
| Hiroo Hasegawa, Yasuaki Yamada, Kanki Komiyama, Masahiko Hayashi, Masami Ishibashi, Toshiaki Sunazuka, Takeshi Izuhara, Kazuyuki Sugahara, Kazuto Tsuruda, Masato Masuda, Nobuyuki Takasu, Kunihiro Tsukasaki, Masao Tomonaga, Shimeru Kamihir. A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) through 15-deoxy-Delta 12, 14 prostaglandin J2 production. Blood. vol 110. issue 5. 2007-10-19. PMID:17551094. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces apoptosis in many transformed cells; however, not all human tumors respond to trail, potentially limiting its therapeutic utility. |
2007-10-19 |
2023-08-12 |
human |
| Yasunari Takada, Bokyung Sung, Gautam Sethi, Madan M Chaturvedi, Bharat B Aggarwa. Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. Biochemical pharmacology. vol 74. issue 7. 2007-10-19. PMID:17692826. |
evidence that genetic deletion of the tnf receptor p60 or p80 inhibits fas mediated apoptosis in macrophages. |
2007-10-19 |
2023-08-12 |
mouse |
| Yasunari Takada, Bokyung Sung, Gautam Sethi, Madan M Chaturvedi, Bharat B Aggarwa. Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. Biochemical pharmacology. vol 74. issue 7. 2007-10-19. PMID:17692826. |
we found that the macrophages expressing tnf receptors were highly sensitive to apoptosis induced by anti-fas. |
2007-10-19 |
2023-08-12 |
mouse |
| Yasunari Takada, Bokyung Sung, Gautam Sethi, Madan M Chaturvedi, Bharat B Aggarwa. Evidence that genetic deletion of the TNF receptor p60 or p80 inhibits Fas mediated apoptosis in macrophages. Biochemical pharmacology. vol 74. issue 7. 2007-10-19. PMID:17692826. |
the genetic deletion of tnf receptors, however, made the cells resistance to anti-fas-induced apoptosis. |
2007-10-19 |
2023-08-12 |
mouse |
| Gakuhei Son, Yuji Iimuro, Ekihiro Seki, Tadamichi Hirano, Yasufumi Kaneda, Jiro Fujimot. Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. American journal of physiology. Gastrointestinal and liver physiology. vol 293. issue 3. 2007-10-11. PMID:17640975. |
in contrast, nf-kappab decoy transferred to isolated hepatic stellate cells (hsc) had no effect on their morphological activation or alpha-sma expression, although the decoy accelerated tumor necrosis factor (tnf)-alpha-induced apoptosis in activated hsc. |
2007-10-11 |
2023-08-12 |
mouse |
| Carmen Garcia-Ruiz, José C Fernández-Chec. Redox regulation of hepatocyte apoptosis. Journal of gastroenterology and hepatology. vol 22 Suppl 1. 2007-10-02. PMID:17567462. |
the antioxidant glutathione (gsh) regulates cell death pathways by modulating the redox state of specific thiol residues of target proteins including transcription factors, stress kinases and caspases, which participate in tumor necrosis factor (tnf)-induced apoptosis. |
2007-10-02 |
2023-08-12 |
Not clear |
| Carmen Garcia-Ruiz, José C Fernández-Chec. Redox regulation of hepatocyte apoptosis. Journal of gastroenterology and hepatology. vol 22 Suppl 1. 2007-10-02. PMID:17567462. |
cytosol gsh regulates tnf hepatocyte apoptosis by modulating caspase 8 activation or nf-kappab-dependent gene expression. |
2007-10-02 |
2023-08-12 |
Not clear |