| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erika Cretney, Kazuyoshi Takeda, Mark J Smyt. Cancer: novel therapeutic strategies that exploit the TNF-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway. The international journal of biochemistry & cell biology. vol 39. issue 2. 2007-06-20. PMID:17097329. |
recombinant tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is currently being developed as a cancer therapeutic since it selectively induces apoptosis in a variety of transformed cells, but not in most normal cells. |
2007-06-20 |
2023-08-12 |
mouse |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
the present study investigated the ability of human choriodecidua to induce myometrial cell apoptosis through the secretion of tumor necrosis factor alpha (tnf). |
2007-06-20 |
2023-08-12 |
human |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
exogenous tnf mimicked lps-treated choriodecidua-conditioned medium in that it induced myometrial cell apoptosis, reduced bcl2 expression, and increased bax expression. |
2007-06-20 |
2023-08-12 |
human |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
using neutralizing antibodies against both subtypes of tnf receptors, we found that only tnfrsf1a participates in tnf-induced myometrial cell apoptosis. |
2007-06-20 |
2023-08-12 |
human |
| b' Marie-Jos\\xc3\\xa8phe Leroy, Emmanuelle Dallot, Isabelle Czerkiewicz, Thomas Schmitz, Michelle Breuiller-Fouch\\xc3\\xa. Inflammation of choriodecidua induces tumor necrosis factor alpha-mediated apoptosis of human myometrial cells. Biology of reproduction. vol 76. issue 5. 2007-06-20. PMID:17215489.' |
our in vitro model of lps-induced inflammation of human fetal membrane explants suggests a mechanism by which tnf secreted by choriodecidua governs human myometrial cell apoptosis at the end of pregnancy. |
2007-06-20 |
2023-08-12 |
human |
| Min-Kyung Choo, Noritaka Kawasaki, Pattama Singhirunnusorn, Keiichi Koizumi, Shintaro Sato, Shizuo Akira, Ikuo Saiki, Hiroaki Sakura. Blockade of transforming growth factor-beta-activated kinase 1 activity enhances TRAIL-induced apoptosis through activation of a caspase cascade. Molecular cancer therapeutics. vol 5. issue 12. 2007-06-07. PMID:17172402. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail/apo2l) is a member of the tnf-alpha ligand family that selectively induces apoptosis in a variety of tumor cells. |
2007-06-07 |
2023-08-12 |
mouse |
| Gautam Sethi, Kwang Seok Ahn, Manoj K Pandey, Bharat B Aggarwa. Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-kappaB-regulated gene products and TAK1-mediated NF-kappaB activation. Blood. vol 109. issue 7. 2007-05-31. PMID:17110449. |
celastrol potentiated the apoptosis induced by tnf and chemotherapeutic agents and inhibited invasion, both regulated by nf-kappab activation. |
2007-05-31 |
2023-08-12 |
Not clear |
| Wei Ju, Xia Wang, Honglian Shi, Wenshu Chen, Steven A Belinsky, Yong Li. A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. Molecular pharmacology. vol 71. issue 5. 2007-05-29. PMID:17296806. |
nuclear factor kappab (nf-kappab) activated by tumor necrosis factor (tnf) attenuates the tnf-induced apoptosis pathway. |
2007-05-29 |
2023-08-12 |
Not clear |
| Wei Ju, Xia Wang, Honglian Shi, Wenshu Chen, Steven A Belinsky, Yong Li. A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cells. Molecular pharmacology. vol 71. issue 5. 2007-05-29. PMID:17296806. |
luteolin effectively suppressed nf-kappab, whereas it potentiated the c-jun n-terminal kinase (jnk) to increase apoptosis induced by tnf in lung cancer cells. |
2007-05-29 |
2023-08-12 |
Not clear |
| Kenji Yanagisawa, Satoshi Yasuda, Masahiro Kai, Shin-ichi Imai, Keiko Yamada, Toshiharu Yamashita, Kowichi Jimbow, Hideo Kanoh, Fumio Sakan. Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation. Biochimica et biophysica acta. vol 1771. issue 4. 2007-05-24. PMID:17276726. |
intriguingly, the overexpression of wild-type (wt) dgkalpha, but not of its kinase-dead (kd) mutant, markedly suppressed tumor necrosis factor (tnf)-alpha-induced apoptosis of aki human melanoma cells. |
2007-05-24 |
2023-08-12 |
human |
| Yoshiya Monden, Toru Kubota, Takaki Tsutsumi, Takahiro Inoue, Shunichi Kawano, Natsumi Kawamura, Tomomi Ide, Kensuke Egashira, Hiroyuki Tsutsui, Kenji Sunagaw. Soluble TNF receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction. Cardiovascular research. vol 73. issue 4. 2007-05-21. PMID:17266945. |
soluble tnf receptors prevent apoptosis in infiltrating cells and promote ventricular rupture and remodeling after myocardial infarction. |
2007-05-21 |
2023-08-12 |
Not clear |
| Kazuhiro Kawamura, Nanami Kawamura, Jin Kumagai, Jun Fukuda, Toshinobu Tanak. Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system. Biology of reproduction. vol 76. issue 4. 2007-05-18. PMID:17182889. |
in early embryos, tnf induces apoptosis, whereas tgfa could act as a survival factor. |
2007-05-18 |
2023-08-12 |
mouse |
| Kazuhiro Kawamura, Nanami Kawamura, Jin Kumagai, Jun Fukuda, Toshinobu Tanak. Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system. Biology of reproduction. vol 76. issue 4. 2007-05-18. PMID:17182889. |
here we investigated the tnf regulation of apoptosis in early mouse embryos and its antagonism by tgfa. |
2007-05-18 |
2023-08-12 |
mouse |
| Kazuhiro Kawamura, Nanami Kawamura, Jin Kumagai, Jun Fukuda, Toshinobu Tanak. Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system. Biology of reproduction. vol 76. issue 4. 2007-05-18. PMID:17182889. |
treatment with tnf inhibited the development of two-cell stage embryos to blastocysts showing decreased proliferation and increased apoptosis both in vitro and in vivo. |
2007-05-18 |
2023-08-12 |
mouse |
| Kazuhiro Kawamura, Nanami Kawamura, Jin Kumagai, Jun Fukuda, Toshinobu Tanak. Tumor necrosis factor regulation of apoptosis in mouse preimplantation embryos and its antagonism by transforming growth factor alpha/phosphatidylionsitol 3-kinase signaling system. Biology of reproduction. vol 76. issue 4. 2007-05-18. PMID:17182889. |
the present findings demonstrate the stage-selective susceptibility to the apoptosis-inducing effect of tnf in mouse preimplantation embryos and that the tgfa/pi3k signaling system has an important role in the control of tnf-induced apoptosis in blastocysts. |
2007-05-18 |
2023-08-12 |
mouse |
| Douglas J Turner, Samuel M Alaish, Tongtong Zou, Jaladanki N Rao, Jian-Ying Wang, Eric D Strauc. Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression. Annals of surgery. vol 245. issue 3. 2007-05-15. PMID:17435549. |
exposure of normal intestinal epithelial cells (iec-6) to the conjugated bile salts taurodeoxycholate (tdca) and taurochenodeoxycholate (tcdca) resulted in an increase in resistance to tumor necrosis factor (tnf)-alpha and cycloheximide (chx)-induced apoptosis, and nf-kappab activation. |
2007-05-15 |
2023-08-12 |
Not clear |
| Jiro Nakagawa, Masanao Saio, Noriyuki Tamakawa, Tatsuhiko Suwa, Alan B Frey, Kenichi Nonaka, Naoki Umemura, Hisashi Imai, Guan-Feng Ouyang, Naoyuki Ohe, Hirohito Yano, Sinichi Yoshimura, Toru Iwama, Tsuyoshi Takam. TNF expressed by tumor-associated macrophages, but not microglia, can eliminate glioma. International journal of oncology. vol 30. issue 4. 2007-05-04. PMID:17332918. |
this notion is supported by the observation that tnf induces apoptosis in gl261 but not mca38 tumors. |
2007-05-04 |
2023-08-12 |
mouse |
| Jan M H Van den Brande, Tamara C Koehler, Zuzana Zelinkova, Roelof J Bennink, Anje A te Velde, Fibo J W ten Cate, Sander J H van Deventer, Maikel P Peppelenbosch, Daniël W Homme. Prediction of antitumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease. Gut. vol 56. issue 4. 2007-05-03. PMID:17082252. |
the human anti-tumour necrosis factor (tnf) antibody infliximab binds to the membrane tnf and subsequently induces apoptosis of activated lamina propria t lymphocytes in patients with crohn's disease in vitro. |
2007-05-03 |
2023-08-12 |
human |
| O Yu Pletjushkina, E K Fetisova, K G Lyamzaev, O Yu Ivanova, L V Domnina, M Yu Vyssokikh, A V Pustovidko, A V Alexeevski, D A Alexeevski, J M Vasiliev, M P Murphy, B V Chernyak, V P Skulache. Hydrogen peroxide produced inside mitochondria takes part in cell-to-cell transmission of apoptotic signal. Biochemistry. Biokhimiia. vol 71. issue 1. 2007-04-30. PMID:16457620. |
tnf, staurosporine, or h2o2 treatment of the inducer cells is shown to initiate apoptosis on the recipient coverslip. |
2007-04-30 |
2023-08-12 |
Not clear |
| Masaki Ueno, Shuhei Tomita, Masaaki Ueki, Yasuyuki Iwanaga, Cheng-Long Huang, Masayuki Onodera, Nobuhiro Maekawa, Frank J Gonzalez, Haruhiko Sakamot. Two pathways of apoptosis are simultaneously induced in the embryonal brains of neural cell-specific HIF-1alpha-deficient mice. Histochemistry and cell biology. vol 125. issue 5. 2007-04-25. PMID:16292520. |
the histochemical and electron microscopic findings indicate that the former represented the appearance of macrophages, in which cellular fragments including vascular cells underwent oxidative stress-related, tnf receptor-mediated, caspase-2-induced apoptosis, while the latter showed c-myc-related, caspase-3-activated apoptosis of the neural cells. |
2007-04-25 |
2023-08-12 |
mouse |