| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Zhao, A Dong, J Gu, Z Liu, Y Zhang, W Zhang, Y Wang, L He, C Qian, Q Qian, X Li. The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer. Cancer gene therapy. vol 13. issue 11. 2007-01-08. PMID:16799468. |
upregulation of trail was observed in tumor cells infected with zd55-il-24 and studies of the apoptotic cascade regulators indicate that zd55-il-24 could further enhance the activation of apoptosis through the tnf family of death receptors. |
2007-01-08 |
2023-08-12 |
mouse |
| P Justo, A B Sanz, M D Sanchez-Niño, J A Winkles, C Lorz, J Egido, A Orti. Cytokine cooperation in renal tubular cell injury: the role of TWEAK. Kidney international. vol 70. issue 10. 2007-01-08. PMID:17003819. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak, tnfsf12) is a member of the tnf superfamily. |
2007-01-08 |
2023-08-12 |
mouse |
| Lutz Thon, Sabine Mathieu, Dieter Kabelitz, Dieter Ada. The murine TRAIL receptor signals caspase-independent cell death through ceramide. Experimental cell research. vol 312. issue 19. 2007-01-03. PMID:17026999. |
here, we demonstrate for the first time that the single murine receptor for (tnf)-related apoptosis-inducing ligand (mtrail-r2) can induce a caspase-independent form of pcd with necrosis-like features in addition to apoptosis. |
2007-01-03 |
2023-08-12 |
Not clear |
| Wulf Schneider-Brachert, Vladimir Tchikov, Oliver Merkel, Marten Jakob, Cora Hallas, Marie-Luise Kruse, Peter Groitl, Alexander Lehn, Eberhard Hildt, Janka Held-Feindt, Thomas Dobner, Dieter Kabelitz, Martin Krönke, Stefan Schütz. Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism. The Journal of clinical investigation. vol 116. issue 11. 2006-12-18. PMID:17024246. |
tnf-mediated apoptosis is initiated by ligand-induced recruitment of tnf receptor-associated death domain (tradd), fas-associated death domain (fadd), and caspase-8 to the death domain of tnf receptor 1 (tnfr1), thereby establishing the death-inducing signaling complex (disc). |
2006-12-18 |
2023-08-12 |
human |
| Ananya De, Jae-Il Park, Kazuhiro Kawamura, Ruby Chen, Cynthia Klein, Rami Rauch, Sabine M Mulders, Maarten D Sollewijn Gelpke, Aaron J W Hsue. Intraovarian tumor necrosis factor-related weak inducer of apoptosis/fibroblast growth factor-inducible-14 ligand-receptor system limits ovarian preovulatory follicles from excessive luteinization. Molecular endocrinology (Baltimore, Md.). vol 20. issue 10. 2006-12-13. PMID:16762976. |
fn14 is the cognate receptor for tnf-related weak inducer of apoptosis (tweak), a tnf superfamily member. |
2006-12-13 |
2023-08-12 |
mouse |
| Koichi Kamata, Seiji Kamijo, Atsuo Nakajima, Akemi Koyanagi, Hisashi Kurosawa, Hideo Yagita, Ko Okumur. Involvement of TNF-like weak inducer of apoptosis in the pathogenesis of collagen-induced arthritis. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 9. 2006-12-13. PMID:17056575. |
tnf-like weak inducer of apoptosis (tweak) is a type ii membrane protein belonging to the tnf family that regulates apoptotic cell death, cellular proliferation, angiogenesis, and inflammation. |
2006-12-13 |
2023-08-12 |
mouse |
| Christian Liedtke, Christian Trautwei. The role of JNK2 in toxic liver injury. Journal of hepatology. vol 45. issue 5. 2006-12-12. PMID:16979778. |
in vitro studies of hepatocytes have implicated over-activation of c-jun n-terminal kinase (jnk) signaling as a mechanism of tumor necrosis factor-alpha (tnf)-induced apoptosis. |
2006-12-12 |
2023-08-12 |
mouse |
| Kathryn Miller-Jensen, Kevin A Janes, Yun-Ling Wong, Linda G Griffith, Douglas A Lauffenburge. Adenoviral vector saturates Akt pro-survival signaling and blocks insulin-mediated rescue of tumor necrosis-factor-induced apoptosis. Journal of cell science. vol 119. issue Pt 18. 2006-12-08. PMID:16940353. |
here we show that infection with an e1/e3-deleted adenoviral vector (adv) sensitizes human epithelial cells to tumor necrosis factor (tnf)-induced apoptosis. |
2006-12-08 |
2023-08-12 |
human |
| Norbert Kociok, Sven Radetzky, Tim U Krohne, Claudia Gavranic, Antonia M Jousse. Pathological but not physiological retinal neovascularization is altered in TNF-Rp55-receptor-deficient mice. Investigative ophthalmology & visual science. vol 47. issue 11. 2006-12-08. PMID:17065527. |
tumor necrosis factor (tnf)-alpha is one of the major cytokines in inflammation and apoptosis. |
2006-12-08 |
2023-08-12 |
mouse |
| Priya Ranjan, Jeremy M Bos. C/EBPbeta regulates TNF induced MnSOD expression and protection against apoptosis. Apoptosis : an international journal on programmed cell death. vol 11. issue 10. 2006-12-04. PMID:16850160. |
c/ebpbeta regulates tnf induced mnsod expression and protection against apoptosis. |
2006-12-04 |
2023-08-12 |
Not clear |
| Priya Ranjan, Jeremy M Bos. C/EBPbeta regulates TNF induced MnSOD expression and protection against apoptosis. Apoptosis : an international journal on programmed cell death. vol 11. issue 10. 2006-12-04. PMID:16850160. |
exposure of c/ebpbeta-deficient fibroblasts to tumor necrosis factor-alpha (tnf) resulted in their death due to apoptosis. |
2006-12-04 |
2023-08-12 |
Not clear |
| Krishnaraj Rajalingam, Manu Sharma, Nicole Paland, Robert Hurwitz, Oliver Thieck, Monique Oswald, Nikolaus Machuy, Thomas Rude. IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS pathogens. vol 2. issue 10. 2006-11-30. PMID:17069460. |
here we investigated the molecular mechanism by which apoptosis induced via the tumor necrosis factor (tnf) receptor is prevented in infected epithelial cells. |
2006-11-30 |
2023-08-12 |
Not clear |
| Boyi Gan, Xu Peng, Tamas Nagy, Ana Alcaraz, Hua Gu, Jun-Lin Gua. Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. The Journal of cell biology. vol 175. issue 1. 2006-11-28. PMID:17015619. |
consistent with this, fip200 ko mouse embryo fibroblasts and liver cells showed increased apoptosis and reduced c-jun n-terminal kinase phosphorylation in response to tumor necrosis factor (tnf) alpha stimulation, which might be mediated by fip200 interaction with apoptosis signal-regulating kinase 1 (ask1) and tnf receptor-associated factor 2 (traf2), regulation of traf2-ask1 interaction, and ask1 phosphorylation. |
2006-11-28 |
2023-08-12 |
mouse |
| Shishir Shishodia, Gautam Sethi, Marina Konopleva, Michael Andreeff, Bharat B Aggarwa. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 12. issue 6. 2006-11-27. PMID:16551868. |
a synthetic triterpenoid, cddo-me, inhibits ikappabalpha kinase and enhances apoptosis induced by tnf and chemotherapeutic agents through down-regulation of expression of nuclear factor kappab-regulated gene products in human leukemic cells. |
2006-11-27 |
2023-08-12 |
human |
| Shishir Shishodia, Gautam Sethi, Marina Konopleva, Michael Andreeff, Bharat B Aggarwa. A synthetic triterpenoid, CDDO-Me, inhibits IkappaBalpha kinase and enhances apoptosis induced by TNF and chemotherapeutic agents through down-regulation of expression of nuclear factor kappaB-regulated gene products in human leukemic cells. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 12. issue 6. 2006-11-27. PMID:16551868. |
overall, our results suggest that cddo-me inhibits nf-kappab through inhibition of ikappabalpha kinase, leading to the suppression of expression of nf-kappab-regulated gene products and enhancement of apoptosis induced by tnf and chemotherapeutic agents. |
2006-11-27 |
2023-08-12 |
human |
| Xinliang Cheng, Ichiro Shimizu, Ying Yuan, Mei Wei, Mi Shen, Huiwei Huang, Mari Urata, Katsutaka Sannomiya, Hiroshi Fukuno, Tomoko Hashimoto-Tamaoki, Susumu It. Effects of estradiol and progesterone on tumor necrosis factor alpha-induced apoptosis in human hepatoma HuH-7 cells. Life sciences. vol 79. issue 21. 2006-11-20. PMID:16860828. |
we examined the proapoptotic role of progesterone as well as the antiapoptotic role of e2 in human hepatoma huh-7 cells in a state of early apoptosis induced by tumor necrosis factor (tnf) alpha. |
2006-11-20 |
2023-08-12 |
human |
| Xinliang Cheng, Ichiro Shimizu, Ying Yuan, Mei Wei, Mi Shen, Huiwei Huang, Mari Urata, Katsutaka Sannomiya, Hiroshi Fukuno, Tomoko Hashimoto-Tamaoki, Susumu It. Effects of estradiol and progesterone on tumor necrosis factor alpha-induced apoptosis in human hepatoma HuH-7 cells. Life sciences. vol 79. issue 21. 2006-11-20. PMID:16860828. |
treatment with the progesterone receptor antagonist ru486 led to the blockage of the progesterone-mediated responses to e2 pretreatment in tnf alpha-induced apoptosis. |
2006-11-20 |
2023-08-12 |
human |
| Xinliang Cheng, Ichiro Shimizu, Ying Yuan, Mei Wei, Mi Shen, Huiwei Huang, Mari Urata, Katsutaka Sannomiya, Hiroshi Fukuno, Tomoko Hashimoto-Tamaoki, Susumu It. Effects of estradiol and progesterone on tumor necrosis factor alpha-induced apoptosis in human hepatoma HuH-7 cells. Life sciences. vol 79. issue 21. 2006-11-20. PMID:16860828. |
these findings demonstrate that e2 inhibits the tnf alpha-induced early apoptosis in hepatoma cells, by suppressing the oxidative stress processes, whereas progesterone acts in a manner opposite from the effects of e2, and the inhibitory effects of e2 were blocked by progesterone, thus leading to the apoptosis of hepatoma cells. |
2006-11-20 |
2023-08-12 |
human |
| Andy Wullaert, Karen Heyninck, Rudi Beyaer. Mechanisms of crosstalk between TNF-induced NF-kappaB and JNK activation in hepatocytes. Biochemical pharmacology. vol 72. issue 9. 2006-11-14. PMID:16934229. |
the observation that mice deficient in the activation of nuclear factor-kappab (nf-kappab) are not viable because of excessive hepatocyte apoptosis induced by tumor necrosis factor (tnf) made it crystal-clear that nf-kappab plays a central role in protecting hepatocytes against tnf-induced cell death. |
2006-11-14 |
2023-08-12 |
mouse |
| Caroline M van Geelen, Jantine L Westra, Elisabeth G de Vries, Wytske Boersma-van Ek, Nynke Zwart, Harry Hollema, H Marike Boezen, Nanno H Mulder, John T Plukker, Steven de Jong, Jan H Kleibeuker, Jan J Koornstr. Prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand and its receptors in adjuvantly treated stage III colon cancer patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. vol 24. issue 31. 2006-11-14. PMID:17075118. |
in preclinical models, there is synergism between chemotherapy and recombinant human tumor necrosis factor (tnf) -related apoptosis-inducing ligand (trail) on apoptosis induction in tumor cells. |
2006-11-14 |
2023-08-12 |
human |