| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flurina Meiler, Maya Zimmermann, Kurt Blaser, Cezmi A Akdis, Mübeccel Akdi. T-cell subsets in the pathogenesis of human asthma. Current allergy and asthma reports. vol 6. issue 2. 2006-09-20. PMID:16566857. |
after migration to asthmatic lung, these cells switch on effector cytokines and induce bronchial epithelial apoptosis with mainly ifn-gamma, tumor necrosis factor (tnf)-alpha, and fas-ligand. |
2006-09-20 |
2023-08-12 |
human |
| b' Vladimir Jurisi\\xc4\\x8. [Characteristics of natural killer cell]. Srpski arhiv za celokupno lekarstvo. vol 134. issue 1-2. 2006-09-20. PMID:16850582.' |
however, nk cells exhibit their effector mechanisms also through apoptosis by non-secretory mechanism mediated by tnf receptor superfamily members. |
2006-09-20 |
2023-08-12 |
Not clear |
| Kazuhiko Nakao, Keisuke Hamasaki, Tatsuki Ichikawa, Kazuhiko Arima, Katsumi Eguchi, Nobuko Ishi. Survivin downregulation by siRNA sensitizes human hepatoma cells to TRAIL-induced apoptosis. Oncology reports. vol 16. issue 2. 2006-09-14. PMID:16820920. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is known to induce cancer cell-specific apoptosis, but hepatoma cells are resistant to trail-induced apoptosis. |
2006-09-14 |
2023-08-12 |
human |
| Adrian A Lobito, Fiona C Kimberley, Jagan R Muppidi, Hirsh Komarow, Adrianna J Jackson, Keith M Hull, Daniel L Kastner, Gavin R Screaton, Richard M Siege. Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS). Blood. vol 108. issue 4. 2006-09-12. PMID:16684962. |
mutant receptors did not bind tnf and failed to function as dominant-negative inhibitors of tnfr1-induced apoptosis. |
2006-09-12 |
2023-08-12 |
mouse |
| R H Tolba, F A Schildberg, C Schnurr, U Glatzel, D Decker, T Mino. Reduced liver apoptosis after venous systemic oxygen persufflation in non-heart-beating donors. Journal of investigative surgery : the official journal of the Academy of Surgical Research. vol 19. issue 4. 2006-09-06. PMID:16835136. |
graft injury caused by warm ischemia in livers from non-heart-beating donors (nhbds) strongly affects posttransplantation outcome and is associated with liver apoptosis, which is mediated by death receptors, such as fas, a surface receptor of the tumor necrosis factor (tnf)-alpha family. |
2006-09-06 |
2023-08-12 |
rat |
| Jos M A Kuijlen, Jan Jakob A Mooij, Inge Platteel, Eelco W Hoving, Winette T A van der Graaf, Mark M Span, Harry Hollema, Wilfred F A den Dunne. TRAIL-receptor expression is an independent prognostic factor for survival in patients with a primary glioblastoma multiforme. Journal of neuro-oncology. vol 78. issue 2. 2006-09-05. PMID:16544055. |
the use of a death inducing ligand such as trail (tnf related apoptosis inducing ligand) seems a promising innovative therapy. |
2006-09-05 |
2023-08-12 |
Not clear |
| Katsuya Shiraki, Katsuhiko Fujikawa, Kazushi Sugimoto, Takeshi Ito, Takenari Yamanaka, Masahiro Suzuki, Kentaro Yoneda, Kazushi Sugimoto, Koujiro Takase, Takeshi Nakan. Cellular apoptosis susceptibility protein and proliferation in human hepatocellular carcinoma. International journal of molecular medicine. vol 18. issue 1. 2006-09-05. PMID:16786158. |
the cellular apoptosis susceptibility protein (cas) is the human homologue of the product of the essential yeast chromosome segregation gene, cse1, and has important roles in tumor necrosis factor (tnf)-induced apoptosis and cell proliferation. |
2006-09-05 |
2023-08-12 |
human |
| Suneel D Mundl. Par-4: a common facilitator/enhancer of extrinsic and intrinsic pathways of apoptosis. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16289745. |
to augment the apoptotic death of jurkat t cells induced by tnf related apoptosis inducing ligand (trail). |
2006-08-31 |
2023-08-12 |
Not clear |
| Simone Boehrer, Daniel Nowak, Elena Puccetti, Martin Ruthardt, Nicole Sattler, Bettina Trepohl, Bernd Schneider, Dieter Hoelzer, Paris S Mitrou, Kai Uwe Cho. Prostate-apoptosis-response-gene-4 increases sensitivity to TRAIL-induced apoptosis. Leukemia research. vol 30. issue 5. 2006-08-31. PMID:16513168. |
the capacity of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) to preferentially induce apoptosis in malignant cells while sparing normal tissues renders it an attractive therapeutic agent. |
2006-08-31 |
2023-08-12 |
Not clear |
| Jianli Niu, Asim Azfer, Michael F Deucher, Pascal J Goldschmidt-Clermont, Pappachan E Kolattukud. Targeted cardiac expression of soluble Fas prevents the development of heart failure in mice with cardiac-specific expression of MCP-1. Journal of molecular and cellular cardiology. vol 40. issue 6. 2006-08-29. PMID:16678847. |
cardiac-specific expression of sfas in mcp mice, in fact, inhibited apoptosis of infiltrating mononuclear cells, normalized circulating c-reactive protein (crp) levels, and prevented macrophage activation as well as production of proinflammatory cytokines, tumor necrosis factor (tnf)-alpha, interleukin (il)-1beta, and il-6 in the hearts. |
2006-08-29 |
2023-08-12 |
mouse |
| Hyungshin Yim, In Sun Hwang, Joon-Seok Choi, Kwang-Hoon Chun, Ying Hua Jin, Young-Mi Ham, Kwang Youl Lee, Seung Ki Le. Cleavage of Cdc6 by caspase-3 promotes ATM/ATR kinase-mediated apoptosis of HeLa cells. The Journal of cell biology. vol 174. issue 1. 2006-08-28. PMID:16801388. |
we show that caspase-3 cleaves cdc6 at d(290)/s and d(442)/g sites, producing p32-tcdc6 (truncated cdc6) and p49-tcdc6, respectively, during etoposide- or tumor necrosis factor (tnf)-alpha-induced apoptosis. |
2006-08-28 |
2023-08-12 |
Not clear |
| Emily Omori, Kunihiro Matsumoto, Hideki Sanjo, Shintaro Sato, Shizuo Akira, Robert C Smart, Jun Ninomiya-Tsuj. TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. The Journal of biological chemistry. vol 281. issue 28. 2006-08-21. PMID:16675448. |
analysis of keratinocytes isolated from the mutant skin revealed that tak1 deficiency results in a striking increase in apoptosis in response to tumor necrosis factor (tnf). |
2006-08-21 |
2023-08-12 |
mouse |
| JiaXuan Zhu, MeeiYueh Liu, Richard H Kennedy, Shi J Li. TNF-alpha-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes. Cytokine. vol 34. issue 1-2. 2006-08-14. PMID:16730193. |
tumor necrosis factor (tnf)-alpha has been shown to induce apoptosis in a variety of cell types including cardiac myocytes. |
2006-08-14 |
2023-08-12 |
Not clear |
| Saskia A G M Cillessen, Chris J L M Meijer, Gert J Ossenkoppele, Kitty C M Castricum, August H Westra, Petra Niesten, Jettie J F Muris, Hoite F Nijdam, Klaas G van der Hem, Marcel Flens, Erik Hooijberg, Joost J Oudejan. Human soluble TRAIL/Apo2L induces apoptosis in a subpopulation of chemotherapy refractory nodal diffuse large B-cell lymphomas, determined by a highly sensitive in vitro apoptosis assay. British journal of haematology. vol 134. issue 3. 2006-08-14. PMID:16848771. |
human soluble tumour necrosis factor (tnf)-related apoptosis-inducing ligand (hstrail/apo2l) induces apoptosis via the alternative, death-receptor mediated apoptosis pathway and might be an effective alternative form of therapy for these lymphomas. |
2006-08-14 |
2023-08-12 |
human |
| Santosh K Sandur, Haruyo Ichikawa, Gautam Sethi, Kwang Seok Ahn, Bharat B Aggarwa. Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. The Journal of biological chemistry. vol 281. issue 25. 2006-08-11. PMID:16624823. |
this led to potentiation of apoptosis induced by tnf and paclitaxel and inhibited cell invasion. |
2006-08-11 |
2023-08-12 |
Not clear |
| Hong-Liang Li, Ai-Bing Wang, Ran Zhang, Yu-Sheng Wei, Hou-Zao Chen, Zhi-Gang She, Yue Huang, De-Pei Liu, Chih-Chuan Lian. A20 inhibits oxidized low-density lipoprotein-induced apoptosis through negative Fas/Fas ligand-dependent activation of caspase-8 and mitochondrial pathways in murine RAW264.7 macrophages. Journal of cellular physiology. vol 208. issue 2. 2006-08-11. PMID:16646083. |
expression of a20 has been shown to protect from tnf-induced apoptosis and also functions via a negative-feedback loop to block nf-kappab activation induced by tnf and other stimuli. |
2006-08-11 |
2023-08-12 |
human |
| Andreas Zwergal, Martina Quirling, Bernd Saugel, Karin C Huth, Carmen Sydlik, Valeria Poli, Dieter Neumeier, H W Löms Ziegler-Heitbrock, Korbinian Bran. C/EBP beta blocks p65 phosphorylation and thereby NF-kappa B-mediated transcription in TNF-tolerant cells. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 1. 2006-08-09. PMID:16785565. |
tnf is a major mediator of inflammation, immunity, and apoptosis. |
2006-08-09 |
2023-08-12 |
Not clear |
| Yongjun Wang, Rajat Singh, Jay H Lefkowitch, Raina M Rigoli, Mark J Czaj. Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway. The Journal of biological chemistry. vol 281. issue 22. 2006-08-07. PMID:16571730. |
in vitro studies of hepatocytes have implicated over-activation of c-jun n-terminal kinase (jnk) signaling as a mechanism of tumor necrosis factor-alpha (tnf)-induced apoptosis. |
2006-08-07 |
2023-08-12 |
mouse |
| M Candolfi, G Jaita, D Pisera, L Ferrari, C Barcia, C Liu, J Yu, G Liu, M G Castro, A Seilicovic. Adenoviral vectors encoding tumor necrosis factor-alpha and FasL induce apoptosis of normal and tumoral anterior pituitary cells. The Journal of endocrinology. vol 189. issue 3. 2006-08-07. PMID:16731798. |
our previous work showed that tumor necrosis factor (tnf)-alpha and fasl induce apoptosis of anterior pituitary cells. |
2006-08-07 |
2023-08-12 |
human |
| Jens Neumeyer, Cora Hallas, Oliver Merkel, Supandi Winoto-Morbach, Marten Jakob, Lutz Thon, Dieter Adam, Wulf Schneider-Brachert, Stefan Schütz. TNF-receptor I defective in internalization allows for cell death through activation of neutral sphingomyelinase. Experimental cell research. vol 312. issue 11. 2006-08-04. PMID:16631736. |
deletion of dd abolishes activation of caspase-3 and -9 and apoptosis following treatment with tnf because of blocked assembly of the disc. |
2006-08-04 |
2023-08-12 |
Not clear |