| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Gao, Jinke Cheng, Tong Shi, Edward T H Ye. Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription. Nature cell biology. vol 8. issue 10. 2006-11-09. PMID:16998474. |
silencing of endogenous bca3 in du145 and mcf7 cells enhanced nfkappab transcription and inhibited tumour necrosis factor (tnf)alpha-induced apoptosis. |
2006-11-09 |
2023-08-12 |
Not clear |
| J R Muppidi, A A Lobito, M Ramaswamy, J K Yang, L Wang, H Wu, R M Siege. Homotypic FADD interactions through a conserved RXDLL motif are required for death receptor-induced apoptosis. Cell death and differentiation. vol 13. issue 10. 2006-11-08. PMID:16410793. |
death receptors in the tnf receptor superfamily signal for apoptosis via the ordered recruitment of fadd and caspase-8 to a death-inducing signaling complex (disc). |
2006-11-08 |
2023-08-12 |
Not clear |
| P M Eimon, E Kratz, E Varfolomeev, S G Hymowitz, H Stern, J Zha, A Ashkenaz. Delineation of the cell-extrinsic apoptosis pathway in the zebrafish. Cell death and differentiation. vol 13. issue 10. 2006-11-08. PMID:16888647. |
the mammalian extrinsic apoptosis pathway is triggered by fas ligand (fasl) and apo2 ligand/tumor necrosis factor (tnf)-related apoptosis-inducing ligand (apo2l/trail). |
2006-11-08 |
2023-08-12 |
drosophila_melanogaster |
| F Abebe, G Bjun. The emergence of Beijing family genotypes of Mycobacterium tuberculosis and low-level protection by bacille Calmette-Guérin (BCG) vaccines: is there a link? Clinical and experimental immunology. vol 145. issue 3. 2006-11-06. PMID:16907905. |
these family strains have developed mechanisms that modulate/suppress immune responses by the host, such as inhibition of apoptosis of infected macrophages, diminished production of interleukin (il)-2, interferon (ifn)-gamma, tumour necrosis factor (tnf)-alpha and elevated levels of il-10 and il-18. |
2006-11-06 |
2023-08-12 |
Not clear |
| R M Moore, J M Mansour, R W Redline, B M Mercer, J J Moor. The physiology of fetal membrane rupture: insight gained from the determination of physical properties. Placenta. vol 27. issue 11-12. 2006-11-03. PMID:16516962. |
our model has also been used to establish the physical properties of individual fetal membrane components (amnion, chorion), determine the sequence of events during the fetal membrane rupture process, and demonstrate that treatment of fetal membranes with tnf or il-1beta, in vitro, induces weakness and the identical biochemical markers of collagen remodeling and apoptosis seen in the physiological weak zone. |
2006-11-03 |
2023-08-12 |
rat |
| Kwang Seok Ahn, Gautam Sethi, Shishir Shishodia, Bokyung Sung, Jack L Arbiser, Bharat B Aggarwa. Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway. Molecular cancer research : MCR. vol 4. issue 9. 2006-11-02. PMID:16966432. |
in this report, we found that honokiol potentiated the apoptosis induced by tumor necrosis factor (tnf) and chemotherapeutic agents, suppressed tnf-induced tumor cell invasion, and inhibited rankl-induced osteoclastogenesis, all of which are known to require nuclear factor-kappab (nf-kappab) activation. |
2006-11-02 |
2023-08-12 |
mouse |
| Michael C Chen, Christopher S Mudge, David J Klump. Urothelial lesion formation is mediated by TNFR1 during neurogenic cystitis. American journal of physiology. Renal physiology. vol 291. issue 4. 2006-10-26. PMID:16622179. |
based on these findings, we conclude that mast cell activation and release of tnf drive urothelial apoptosis and lesion formation in a murine neurogenic cystitis model, and we hypothesize that anti-tnf therapy may stabilize bladder barrier function in ic patients. |
2006-10-26 |
2023-08-12 |
mouse |
| David Liuwantara, Mark Elliot, Mariya W Smith, Andrew O Yam, Stacy N Walters, Eliana Marino, Andy McShea, Shane T Gre. Nuclear factor-kappaB regulates beta-cell death: a critical role for A20 in beta-cell protection. Diabetes. vol 55. issue 9. 2006-10-24. PMID:16936197. |
we report that inhibition of gene transcription sensitized beta-cells to tumor necrosis factor (tnf)-alpha-induced apoptosis, indicating the presence of a regulated antiapoptotic response. |
2006-10-24 |
2023-08-12 |
mouse |
| Delphine Mérino, Najoua Lalaoui, Alexandre Morizot, Pascal Schneider, Eric Solary, Olivier Michea. Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2. Molecular and cellular biology. vol 26. issue 19. 2006-10-24. PMID:16980609. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf family that induces cancer cell death by apoptosis with some selectivity. |
2006-10-24 |
2023-08-12 |
Not clear |
| Louis Tong, Zhuo Chen, Cintia S De Paiva, Roger Beuerman, De-Quan Li, Stephen C Pflugfelde. Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cells. Investigative ophthalmology & visual science. vol 47. issue 10. 2006-10-24. PMID:17003418. |
this study evaluates the role of transglutaminase in regulating tumor necrosis factor (tnf) receptor clustering as well as caspase activation in uvb-induced apoptosis in human corneal epithelial cells. |
2006-10-24 |
2023-08-12 |
human |
| Kyung-Hee Lee, Eun-Mi Cho. Rubus coreanus Miq. extract promotes osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells. The American journal of Chinese medicine. vol 34. issue 4. 2006-10-16. PMID:16883635. |
treatment with rce (10approximately50 microg/ml) decreased the 0.2 mm h(2)o(2)-induced apoptosis and production of tumor necrosis factor (tnf)-alpha, interleukin (il)-6 and nitric oxide (no) in osteoblasts. |
2006-10-16 |
2023-08-12 |
Not clear |
| Han-Ming Shen, Shazib Pervai. TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 20. issue 10. 2006-10-05. PMID:16873882. |
tumor necrosis factor (tnf) superfamily is a group of cytokines with important functions in immunity, inflammation, differentiation, control of cell proliferation, and apoptosis. |
2006-10-05 |
2023-08-12 |
Not clear |
| Jaya Dasgupta, Sita Subbaram, Kip M Connor, Ana M Rodriguez, Oren Tirosh, Joseph S Beckman, David Jourd'Heuil, J Andrés Melende. Manganese superoxide dismutase protects from TNF-alpha-induced apoptosis by increasing the steady-state production of H2O2. Antioxidants & redox signaling. vol 8. issue 7-8. 2006-10-05. PMID:16910777. |
here we demonstrate that the antiapoptotic effects of sod2 are attributed to its ability to generate h(2)o(2) and that its efficient removal resensitizes cells to tumor necrosis factor (tnf)-alpha-induced apoptosis. |
2006-10-05 |
2023-08-12 |
Not clear |
| Haruyo Ichikawa, Yasunari Takada, Shishir Shishodia, Bolleddula Jayaprakasam, Muraleedharan G Nair, Bharat B Aggarwa. Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression. Molecular cancer therapeutics. vol 5. issue 6. 2006-10-04. PMID:16818501. |
consequently, withanolide suppressed the expression of tnf-induced nf-kappab-regulated antiapoptotic (inhibitor of apoptosis protein 1, bfl-1/a1, and fadd-like interleukin-1beta-converting enzyme-inhibitory protein) and metastatic (cyclooxygenase-2 and intercellular adhesion molecule-1) gene products, enhanced the apoptosis induced by tnf and chemotherapeutic agents, and suppressed cellular tnf-induced invasion and receptor activator of nf-kappab ligand-induced osteoclastogenesis. |
2006-10-04 |
2023-08-12 |
Not clear |
| Derick Han, Naoko Hanawa, Behnam Saberi, Neil Kaplowit. Hydrogen peroxide and redox modulation sensitize primary mouse hepatocytes to TNF-induced apoptosis. Free radical biology & medicine. vol 41. issue 4. 2006-10-03. PMID:16863996. |
the implication for liver disease is that concomitant tnf exposure and reactive oxygen species, either extrinsically generated (e.g., nonparenchymal or inflammatory cells) or intrinsically generated in hepatocytes (e.g., mitochondria), may act in concert to promote apoptosis and liver injury. |
2006-10-03 |
2023-08-12 |
mouse |
| Sean Campbell, Jennifer Michaelson, Linda Burkly, Chaim Putterma. The role of TWEAK/Fn14 in the pathogenesis of inflammation and systemic autoimmunity. Frontiers in bioscience : a journal and virtual library. vol 9. 2006-09-28. PMID:15353286. |
tnf-like weak inducer of apoptosis (tweak), a recently identified member of the tnf ligand family, induces pge2, mmp-1, il-6, il-8, rantes, and ip-10 in fibroblasts and synoviocytes, and upregulates icam-1, e-selectin, il-8, and mcp-1 in endothelial cells. |
2006-09-28 |
2023-08-12 |
human |
| R L VanOosten, J K Earel, T S Griffit. Enhancement of Ad5-TRAIL cytotoxicity against renal cell carcinoma with histone deacetylase inhibitors. Cancer gene therapy. vol 13. issue 6. 2006-09-25. PMID:16456549. |
the tumor necrosis factor (tnf) family member tnf-related apoptosis-inducing ligand (trail)/apo-2l induces apoptosis in various tumor cell types, while having little cytotoxicity against normal cells. |
2006-09-25 |
2023-08-12 |
human |
| Gautam Sethi, Kwang Seok Ahn, Santosh K Sandur, Xin Lin, Madan M Chaturvedi, Bharat B Aggarwa. Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway. The Journal of biological chemistry. vol 281. issue 33. 2006-09-25. PMID:16785236. |
this correlated with enhancement of the apoptosis induced by tnf and the chemotherapeutic agent taxol in human leukemic kbm-5 cells. |
2006-09-25 |
2023-08-12 |
human |
| Stuart J Perper, Beth Browning, Linda C Burkly, Shawn Weng, Cindy Gao, Keith Giza, Lihe Su, Leticia Tarilonte, Thomas Crowell, Luis Rajman, Laura Runkel, Martin Scott, Gerald J Atkins, David M Findlay, Timothy S Zheng, Henry Hes. TWEAK is a novel arthritogenic mediator. Journal of immunology (Baltimore, Md. : 1950). vol 177. issue 4. 2006-09-25. PMID:16888023. |
tnf-like weak inducer of apoptosis (tweak) is a tnf family member with pleiotropic effects on a variety of cell types, one of which is the induction of proinflammatory cytokines by synovial fibroblasts derived from rheumatoid arthritis (ra) patients. |
2006-09-25 |
2023-08-12 |
mouse |
| F J Lejeune, C Rüeg. Recombinant human tumor necrosis factor: an efficient agent for cancer treatment. Bulletin du cancer. vol 93. issue 8. 2006-09-21. PMID:16935777. |
high tnf dosages induce endothelial cells apoptosis, leading to vascular destruction. |
2006-09-21 |
2023-08-12 |
human |