| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew S Cowburn, Anastasia Sobolewski, Ben J Reed, John Deighton, Joanna Murray, Karen A Cadwallader, John R Bradley, Edwin R Chilver. Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils. The Journal of biological chemistry. vol 281. issue 18. 2006-06-28. PMID:16533817. |
we have shown previously that tumor necrosis factor-alpha (tnfalpha) enhances the rate of neutrophil apoptosis at early time points via a mechanism involving both tnf receptor (tnfr) i and tnfrii. |
2006-06-28 |
2023-08-12 |
human |
| Takeshi Hori. [Pathophysiological role of cytokines in heart failure]. Nihon rinsho. Japanese journal of clinical medicine. vol 64. issue 5. 2006-06-15. PMID:16689363. |
in addition, tnf and interleukin induce myocardial apoptosis and promote cardiac hypertrophy and fibrosis, suggesting that these cytokines are involved in the progression of cardiac remodeling. |
2006-06-15 |
2023-08-12 |
Not clear |
| Hiroshi Irie, Junji Shig. Pathogenesis of herpes simplex hepatitis in macrophage-depleted mice: possible involvement of tumor necrosis factor-alpha and inducible nitric oxide synthase in massive apoptosis. Anatomical science international. vol 80. issue 4. 2006-06-12. PMID:16333916. |
tumor necrosis factor (tnf)-alpha, inducible nitric oxide synthase (inos), interferon (ifn)-alpha, and interleukin-6 mrnas were detected to a much greater extent in silica-treated mice compared with control mice after hsv-1 infection, and excessive expression of inos mrna and cytokine mrnas in the liver may be closely related to massive liver cell apoptosis. |
2006-06-12 |
2023-08-12 |
mouse |
| Akira Okano, Hisashi Kishi, Hitomi Takahashi, Masashi Takahash. Tumor necrosis factor-alpha induces apoptosis in cultured porcine luteal cells. The Journal of reproduction and development. vol 52. issue 2. 2006-06-12. PMID:16415567. |
some studies in mammalian species recently demonstrated that tumor necrosis factor (tnf)-alpha plays an important role for corpus luteum (cl) function by way of apoptosis during the estrous cycle. |
2006-06-12 |
2023-08-12 |
Not clear |
| Jeffrey A Winkles, Nhan L Tran, Michael E Beren. TWEAK and Fn14: new molecular targets for cancer therapy? Cancer letters. vol 235. issue 1. 2006-06-08. PMID:15885893. |
tumor necrosis factor-like weak inducer of apoptosis (tweak) is a member of the tumor necrosis factor (tnf) superfamily of structurally related cytokines. |
2006-06-08 |
2023-08-12 |
human |
| Octavian Bucur, Subrata Ray, Maria Cristina Bucur, Alexandru Almasa. APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in prostate cancer therapy. Frontiers in bioscience : a journal and virtual library. vol 11. 2006-06-02. PMID:16368536. |
apo2 ligand (apo2l), also called tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), is one of several members of the tnf gene superfamily that induces apoptosis through engagement of death receptors. |
2006-06-02 |
2023-08-12 |
Not clear |
| Toshiharu Sakurai, Katsuhiko Itoh, Hiroaki Higashitsuji, Kohsuke Nonoguchi, Yu Liu, Hirohiko Watanabe, Tadasu Nakano, Manabu Fukumoto, Tsutomu Chiba, Jun Fujit. Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase. Biochimica et biophysica acta. vol 1763. issue 3. 2006-06-02. PMID:16569452. |
in balb/3t3 cells treated with tumor necrosis factor (tnf)-alpha and cycloheximide, the down-shift in temperature from 37 degrees c to 32 degrees c increased the expression of cirp and suppressed the apoptosis. |
2006-06-02 |
2023-08-12 |
mouse |
| Sören T Eichhors. Modulation of apoptosis as a target for liver disease. Expert opinion on therapeutic targets. vol 9. issue 1. 2006-06-01. PMID:15757484. |
the extrinsic pathway is triggered from the cell surface by engagement of death receptors as cd95, trail (tnf-related apoptosis inducing ligand) and tnf (tumour necrosis factor) or tgf-beta (transforming growth factor beta) receptors. |
2006-06-01 |
2023-08-12 |
Not clear |
| Lauren Clancy, Karen Mruk, Kristina Archer, Melissa Woelfel, Juthathip Mongkolsapaya, Gavin Screaton, Michael J Lenardo, Francis Ka-Ming Cha. Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 50. 2006-05-30. PMID:16319225. |
hence, whereas most tnf receptors normally form only homotrimeric complexes, the preligand assembly domains in tr2 and tr4 permit mixed complex formation as a means to regulate apoptosis induction. |
2006-05-30 |
2023-08-12 |
Not clear |
| Nickolay Neznanov, Lubov Neznanova, Brigitte Angres, Andrei V Gudko. Serologically defined colon cancer antigen 3 is necessary for the presentation of TNF receptor 1 on cell surface. DNA and cell biology. vol 24. issue 12. 2006-05-30. PMID:16332174. |
tumor necrosis factor (tnf) induces apoptosis in sensitive cells in culture when used in combination with inhibitors of transcription or translation. |
2006-05-30 |
2023-08-12 |
mouse |
| Yasunari Takada, Ann Gillenwater, Haruyo Ichikawa, Bharat B Aggarwa. Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. The Journal of biological chemistry. vol 281. issue 9. 2006-05-23. PMID:16377638. |
we found that in several human cancer cell lines, saha potentiated the apoptosis induced by tumor necrosis factor (tnf) and chemotherapeutic agents and inhibited tnf-induced invasion and receptor activator of nf-kappab ligand-induced osteoclastogenesis, all of which are known to require nf-kappab activation. |
2006-05-23 |
2023-08-12 |
human |
| Yuriko Hirota, Manabu Habu, Kazuhiro Tominaga, Miho Sukedai, Akihiro Matsukawa, Tatsuji Nishihara, Jinichi Fukud. Relationship between TNF-alpha and TUNEL-positive chondrocytes in antigen-induced arthritis of the rabbit temporomandibular joint. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 35. issue 2. 2006-05-18. PMID:16430739. |
tumor necrosis factor (tnf)-alpha is closely associated with changes in condylar cartilage and modulates apoptosis in various tissues including cartilage. |
2006-05-18 |
2023-08-12 |
rabbit |
| Marcelo Chiara Bertolam. [Mechanisms of hepatotoxicity]. Arquivos brasileiros de cardiologia. vol 85 Suppl 5. 2006-05-11. PMID:16400394. |
apoptosis mediated by tnf and fas (immune mediated). |
2006-05-11 |
2023-08-12 |
Not clear |
| Feng Dong, Carrie H Hall, Suzanne A Golech, Nora B Philbin, Jennifer P Rice, Jennifer Gurney, Francoise G Arnaud, Michael Hammett, Xia Ma, W Shannon Flournoy, Jiang Hong, Lewis J Kaplan, L Bruce Pearce, Gerald McGwin, Stephen Ahlers, Richard McCarron, Daniel Freilic. Immune effects of resuscitation with HBOC-201, a hemoglobin-based oxygen carrier, in swine with moderately severe hemorrhagic shock from controlled hemorrhage. Shock (Augusta, Ga.). vol 25. issue 1. 2006-05-10. PMID:16369186. |
sequential whole-blood samples were collected for analyses of leukocyte differential (hematology analyzer), t-lymphocyte subsets (cd3, cd4, and cd8) (facs), lymphocyte adhesion marker cd49d (alpha4-integrin) expression (facs), plasma cytokines-tumor necrosis factor (tnf)-alpha, interleukin (il)-6, and il-10-(elisa), and lymphocyte apoptosis (annexin-v/propidium iodide staining) (facs). |
2006-05-10 |
2023-08-12 |
Not clear |
| Yoshinao Hosaka, Rikio Kirisawa, Hiromi Ueda, Mamoru Yamaguchi, Kazushige Takehan. Differences in tumor necrosis factor (TNF)alpha and TNF receptor-1-mediated intracellular signaling factors in normal, inflamed and scar-formed horse tendons. The Journal of veterinary medical science. vol 67. issue 10. 2006-05-05. PMID:16276053. |
tumor necrosis factor (tnf) receptors (tnf-r)-mediated cell survival or apoptosis has been demonstrated in many cells, but little is known about survival or apoptotic signals via tnf-r1 in tendinocytes. |
2006-05-05 |
2023-08-12 |
Not clear |
| Paul W Sylvester, Sumit Sha. Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells. Asia Pacific journal of clinical nutrition. vol 14. issue 4. 2006-05-01. PMID:16326643. |
since caspase-8 activation is associated with the activation of death receptors, such as fas, tumor necrosis factor (tnf), or tnf-related apoptosis-inducing ligand (trail) receptors, studies were conducted to determine the exact death receptor(s) and ligand(s) involved in mediating tocotrienol-induced caspase-8 activation and apoptosis. |
2006-05-01 |
2023-08-12 |
mouse |
| Concetta Bubici, Salvatore Papa, Can G Pham, Francesca Zazzeroni, Guido Franzos. NF-kappaB and JNK: an intricate affair. Cell cycle (Georgetown, Tex.). vol 3. issue 12. 2006-04-28. PMID:15611622. |
nf-kappab/rel transcription factors block apoptosis or programmed cell death (pcd) induced by tumor necrosis factor (tnf) alpha. |
2006-04-28 |
2023-08-12 |
Not clear |
| Yasunari Takada, Haruyo Ichikawa, Vladimir Badmaev, Bharat B Aggarwa. Acetyl-11-keto-beta-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-kappa B and NF-kappa B-regulated gene expression. Journal of immunology (Baltimore, Md. : 1950). vol 176. issue 5. 2006-04-28. PMID:16493072. |
we found that akba potentiated the apoptosis induced by tnf and chemotherapeutic agents, suppressed tnf-induced invasion, and inhibited receptor activator of nf-kappab ligand-induced osteoclastogenesis, all of which are known to require nf-kappab activation. |
2006-04-28 |
2023-08-12 |
Not clear |
| Mamoun Younes, Georgios V Georgakis, Mahdis Rahmani, David Beer, Anas Youne. Functional expression of TRAIL receptors TRAIL-R1 and TRAIL-R2 in esophageal adenocarcinoma. European journal of cancer (Oxford, England : 1990). vol 42. issue 4. 2006-04-25. PMID:16426839. |
the tumour necrosis factor (tnf) related apoptosis-inducing ligand (trail/apo2l) is a member of the tnf superfamily that preferentially induces apoptosis in cancer cells, while sparing normal cells. |
2006-04-25 |
2023-08-12 |
human |
| Nicole Brown, Mitzi Nagarkatti, Prakash S Nagarkatt. Induction of apoptosis in murine fetal thymocytes following perinatal exposure to diethylstilbestrol. International journal of toxicology. vol 25. issue 1. 2006-04-25. PMID:16510352. |
taken together, these results suggest that des-induced thymic atrophy following perinatal exposure may result, at least in part, from increased apoptosis mediated by death receptor pathway involving tnf family members. |
2006-04-25 |
2023-08-12 |
mouse |