| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H-Y Zhang, J-H Man, B Liang, T Zhou, C-H Wang, T Li, H-Y Li, W-H Li, B-F Jin, P-J Zhang, J Zhao, X Pan, K He, W-L Gong, X-M Zhang, A-L L. Tumor-targeted delivery of biologically active TRAIL protein. Cancer gene therapy. vol 17. issue 5. 2010-07-30. PMID:20075981. |
the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a potent inducer of tumor cell apoptosis, but concerns of considerable liver toxicity limit its uses in human cancer therapy. |
2010-07-30 |
2023-08-12 |
mouse |
| Lars Vereecke, Mozes Sze, Conor Mc Guire, Brecht Rogiers, Yuanyuan Chu, Marc Schmidt-Supprian, Manolis Pasparakis, Rudi Beyaert, Geert van Lo. Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis. The Journal of experimental medicine. vol 207. issue 7. 2010-07-30. PMID:20530205. |
a20 is a nuclear factor kappab (nf-kappab) target gene that encodes a ubiquitin-editing enzyme that is essential for the termination of nf-kappab activation after tumor necrosis factor (tnf) or microbial product stimulation and for the prevention of tnf-induced apoptosis. |
2010-07-30 |
2023-08-12 |
mouse |
| Gen-Hong Yao, Ya-Yi Ho. [Recent advances for research on anti-tumor effects of TNF-related apoptosis-inducing ligand]. Wei sheng yan jiu = Journal of hygiene research. vol 35. issue 1. 2010-07-29. PMID:16598953. |
tumor necrosis factor (tnf)-related apoptosis--inducing ligand (trail) is a member of tnf family. |
2010-07-29 |
2023-08-12 |
Not clear |
| Charles S Vi. Advances in lupus stemming from the parent-into-F1 model. Trends in immunology. vol 31. issue 6. 2010-07-29. PMID:20362509. |
then we focus on recent work in parent-into-f1 mice, which has yielded novel insights into unresolved controversies, such as the role of apoptosis in the pathogenesis of lupus and lupus in patients receiving tnf blockade. |
2010-07-29 |
2023-08-12 |
mouse |
| Maria Russo, Annalisa Mupo, Carmela Spagnuolo, Gian Luigi Russ. Exploring death receptor pathways as selective targets in cancer therapy. Biochemical pharmacology. vol 80. issue 5. 2010-07-19. PMID:20302848. |
a recent and innovative strategy in cancer therapy is the activation of apoptosis in tumour cells specifically expressing death receptors (dr) belonging to the tumour necrosis factor (tnf) receptor superfamily and including several members known since the early '90. |
2010-07-19 |
2023-08-12 |
Not clear |
| M Garofalo, G L Condorelli, C M Croce, G Condorell. MicroRNAs as regulators of death receptors signaling. Cell death and differentiation. vol 17. issue 2. 2010-07-13. PMID:19644509. |
death receptors, belonging to the tnf receptor superfamily, induce apoptosis through two different pathways, one involving the effector caspases directly (type i cells or mitochondria-independent death), the other one amplifying the death signal through the mitochondrial pathway (type ii cells or mitochondria-dependent death). |
2010-07-13 |
2023-08-12 |
Not clear |
| Nicole Müller, Britta Schneider, Klaus Pfizenmaier, Harald Wajan. Superior serum half life of albumin tagged TNF ligands. Biochemical and biophysical research communications. vol 396. issue 4. 2010-07-13. PMID:20447380. |
due to their immune stimulating and apoptosis inducing properties, ligands of the tnf family attract increasing interest as therapeutic proteins. |
2010-07-13 |
2023-08-12 |
human |
| Giuseppina Cantarella, Giulia Di Benedetto, Mimmo Scollo, Irene Paterniti, Salvatore Cuzzocrea, Paolo Bosco, Giuseppe Nocentini, Carlo Riccardi, Renato Bernardin. Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 6. 2010-07-12. PMID:20107429. |
in particular, the inducers of apoptosis belonging to tnf receptor superfamily and their respective ligands are upregulated after sci. |
2010-07-12 |
2023-08-12 |
mouse |
| Lei Fu, De-ming Tan, Shi-fang Peng, Zhou-hua Ho. [The effect of human sTNFR1 gene transfection on QSG7701 cell apoptosis induced by TNF alpha]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. vol 15. issue 10. 2010-07-08. PMID:17963610. |
[the effect of human stnfr1 gene transfection on qsg7701 cell apoptosis induced by tnf alpha]. |
2010-07-08 |
2023-08-12 |
human |
| Miho Sekiguchi, Yasufumi Sekiguchi, Shin-Ichi Konno, Hideo Kobayashi, Yoshimi Homma, Shin-Ichi Kikuch. Comparison of neuropathic pain and neuronal apoptosis following nerve root or spinal nerve compression. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. vol 18. issue 12. 2010-07-08. PMID:19543754. |
the aim of this study was to determine which compression injury was more painful and to compare behavior with expression of tumor necrosis factor (tnf)-alpha in drg and apoptosis in the drg following crush injury to the l5 nerve root or l5 spinal nerve. |
2010-07-08 |
2023-08-12 |
rat |
| Katsuhito Mori, Yuji Ikari, Shuichi Jono, Atsushi Shioi, Eiji Ishimura, Masanori Emoto, Masaaki Inaba, Kazuhiro Hara, Yoshiki Nishizaw. Association of serum TRAIL level with coronary artery disease. Thrombosis research. vol 125. issue 4. 2010-07-02. PMID:20034655. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the tnf ligand family, and is able to induce apoptosis in tumor cells. |
2010-07-02 |
2023-08-12 |
human |
| K Choi, S-W Ryu, S Song, H Choi, S W Kang, C Cho. Caspase-dependent generation of reactive oxygen species in human astrocytoma cells contributes to resistance to TRAIL-mediated apoptosis. Cell death and differentiation. vol 17. issue 5. 2010-06-28. PMID:19876066. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), a member of the tnf family of cytokines, causes apoptosis by caspase activation in various cell types, particularly in transformed cells. |
2010-06-28 |
2023-08-12 |
human |
| Peter D Mace, Callum Smits, David L Vaux, John Silke, Catherine L Da. Asymmetric recruitment of cIAPs by TRAF2. Journal of molecular biology. vol 400. issue 1. 2010-06-28. PMID:20447407. |
cellular inhibitor of apoptosis protein (ciap) 1 and ciap2 set the balance between transcription factor and apoptosis signaling downstream of tumor necrosis factor (tnf) receptor superfamily members by acting as ubiquitin e3 ligases for substrates that are part of the tnf receptor complex. |
2010-06-28 |
2023-08-12 |
Not clear |
| Rebecca Feltham, Maryline Moulin, James E Vince, Peter D Mace, Wendy Wei-Lynn Wong, Holly Anderton, Catherine L Day, David L Vaux, John Silk. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. The Journal of biological chemistry. vol 285. issue 23. 2010-06-24. PMID:20356846. |
tumor necrosis factor (tnf) signaling, but not tweak (tnf-like weak inducer of apoptosis)-triggered ciap1 (cellular inhibitor of apoptosis protein 1) degradation, requires ciap1 ring dimerization and e2 binding. |
2010-06-24 |
2023-08-12 |
Not clear |
| Rebecca Feltham, Maryline Moulin, James E Vince, Peter D Mace, Wendy Wei-Lynn Wong, Holly Anderton, Catherine L Day, David L Vaux, John Silk. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. The Journal of biological chemistry. vol 285. issue 23. 2010-06-24. PMID:20356846. |
cellular inhibitor of apoptosis (ciap) proteins, ciap1 and ciap2, are important regulators of tumor necrosis factor (tnf) superfamily (sf) signaling and are amplified in a number of tumor types. |
2010-06-24 |
2023-08-12 |
Not clear |
| Sharron A N Brown, Arundhati Ghosh, Jeffrey A Winkle. Full-length, membrane-anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF-kappaB pathway. The Journal of biological chemistry. vol 285. issue 23. 2010-06-24. PMID:20385556. |
tweak (tnf-like weak inducer of apoptosis), a member of the tnf family, is a multifunctional cytokine that acts via binding to a cell surface receptor named fn14 (fibroblast growth factor-inducible 14). |
2010-06-24 |
2023-08-12 |
human |
| Peter Vandenabeele, Wim Declercq, Franky Van Herreweghe, Tom Vanden Bergh. The role of the kinases RIP1 and RIP3 in TNF-induced necrosis. Science signaling. vol 3. issue 115. 2010-06-21. PMID:20354226. |
tnf signaling can lead to three distinct outcomes, each of which is initiated by different signaling complexes: the gene induction or survival mode, the apoptosis mode, and the necrosis mode. |
2010-06-21 |
2023-08-12 |
Not clear |
| Y Chen, M Hanaoka, Y Droma, P Chen, N F Voelkel, K Kub. Endothelin-1 receptor antagonists prevent the development of pulmonary emphysema in rats. The European respiratory journal. vol 35. issue 4. 2010-06-18. PMID:19897563. |
the expression of et(a) receptor, apoptosis index, caspase-3 activity, matrix metalloproteinase (mmp)-2 and mmp-9 activity, and tumour necrosis factor (tnf)-alpha and interleukin (il)-1beta concentrations were measured in the lung tissue. |
2010-06-18 |
2023-08-12 |
rat |
| Yumiko Kanno, Daisuke Sakurai, Hidenori Hase, Hidefumi Kojima, Tetsuji Kobat. TACI induces cIAP1-mediated ubiquitination of NIK by TRAF2 and TANK to limit non-canonical NF-kappaB signaling. Journal of receptor and signal transduction research. vol 30. issue 2. 2010-06-17. PMID:20184394. |
in this study, we showed that constitutive activation of taci signaling suppressed baff-r-mediated nf-kappab2 p100 processing with the up-regulation of cellular inhibitors of apoptosis 1 (ciap1) and tnf receptor associated factor (traf)-associated nf-kappab activator (tank). |
2010-06-17 |
2023-08-12 |
Not clear |
| Zhen Wei Xia, Qi Qi, Xue Hong Zhang, Qing Xiang Shen, Yun Zhu Li, Shan Chang Y. [The study on the construction of expression plasmid containing rHO-1 cDNA, analysis of rHO-1 activity and function of anti-apoptosis in HUVEC]. Shi yan sheng wu xue bao. vol 38. issue 5. 2010-06-15. PMID:16363125. |
the apoptosis of huvec induced by tumor necrosis factor (tnf)-alpha was analyzed by flow cytometry. |
2010-06-15 |
2023-08-12 |
human |