| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vladimir Tchikov, Uwe Bertsch, Jürgen Fritsch, Bärbel Edelmann, Stefan Schütz. Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways. European journal of cell biology. vol 90. issue 6-7. 2011-09-27. PMID:21144616. |
the biological significance of tnf receptor-1 compartmentalization is demonstrated by the strategy of adenoviruses to impede tnf-r1 internalization and by this preventing host cell apoptosis. |
2011-09-27 |
2023-08-12 |
Not clear |
| U Fiocco, S Bombardier. [Differences in pharmacology of tumor necrosis factor (TNF) antagonists]. Reumatismo. vol 57. issue 4 Suppl. 2011-09-15. PMID:16385350. |
in order to explain the clinical differences observed when these agents are used in the "real world", which can arise from the respective pk characteristics (kinetics, route and frequency of administration, type of tnf binding, effects on cytokines) and pd responses and peculiar mechanisms of action, with distinctive immune function (lftα inactivation; apoptosis induction, tnf immunoprecipitation, c1q binding and cdc induction; fcγ cross-linking and adcc induction), the dynamics of interaction of the two classes of neutralizing molecules with tnf, and the ability in restoring tnf homeostasis, are outlined. |
2011-09-15 |
2023-08-12 |
Not clear |
| Juan A Moreno, Maria C Izquierdo, Maria D Sanchez-Niño, Beatriz Suárez-Alvarez, Carlos Lopez-Larrea, Aniela Jakubowski, Julia Blanco, Rafael Ramirez, Rafael Selgas, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz, Ana B San. The inflammatory cytokines TWEAK and TNFα reduce renal klotho expression through NFκB. Journal of the American Society of Nephrology : JASN. vol 22. issue 7. 2011-09-12. PMID:21719790. |
whether proinflammatory cytokines, such as tnf and tnf-like weak inducer of apoptosis (tweak), modulate klotho is unknown. |
2011-09-12 |
2023-08-12 |
mouse |
| Yumiko Yasui, Masashi Hosokawa, Nana Mikami, Kazuo Miyashita, Takuji Tanak. Dietary astaxanthin inhibits colitis and colitis-associated colon carcinogenesis in mice via modulation of the inflammatory cytokines. Chemico-biological interactions. vol 193. issue 1. 2011-09-09. PMID:21621527. |
ax-feeding suppressed expression of inflammatory cytokines, including nuclear factor (nf)-κb, tumor necrosis factor (tnf)-α and interleukin (il)-1β, inhibited proliferation, and induced apoptosis in the colonic adenocarcinomas. |
2011-09-09 |
2023-08-12 |
mouse |
| Aminah Ikner, Avi Ashkenaz. TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8. The Journal of biological chemistry. vol 286. issue 24. 2011-08-30. PMID:21525013. |
the tumor necrosis factor (tnf) superfamily member tnf-like weak inducer of apoptosis (tnfsf12, cd255) (tweak) can stimulate apoptosis in certain cancer cells. |
2011-08-30 |
2023-08-12 |
Not clear |
| Lyubov Zaitseva, Stuart A Rushworth, David J MacEwa. Silencing FLIP(L) modifies TNF-induced apoptotic protein expression. Cell cycle (Georgetown, Tex.). vol 10. issue 7. 2011-08-09. PMID:21403465. |
here, we shown that silencing flipl in hek 293 cells changed the expression levels of proteins that are involved in both extrinsic and intrinsic apoptosis, as well as regulating tumor necrosis factor-α (tnf)-mediated apoptotic patterns. |
2011-08-09 |
2023-08-12 |
Not clear |
| Naoya Kawano, Katsuhito Mori, Masanori Emoto, Eiko Lee, Ikue Kobayashi, Yuko Yamazaki, Hiromi Urata, Tomoaki Morioka, Hidenori Koyama, Tetsuo Shoji, Yoshiki Nishizawa, Masaaki Inab. Association of serum TRAIL levels with atherosclerosis in patients with type 2 diabetes mellitus. Diabetes research and clinical practice. vol 91. issue 3. 2011-08-08. PMID:21227528. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) was originally isolated as an inducer of apoptosis. |
2011-08-08 |
2023-08-12 |
Not clear |
| Y Liu, F Lang, X Xie, S Prabhu, J Xu, D Sampath, K Aldape, G Fuller, V K Puduvall. Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts. Cell death & disease. vol 2. 2011-08-05. PMID:21368892. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) selectively induces apoptosis in malignant cells, including gliomas, and is currently in anticancer clinical trials. |
2011-08-05 |
2023-08-12 |
human |
| J Sawicka-Powierza, E Jablonska, J Kloczko, J Piszcz, M Garley, W Ratajczk-Wron. Evaluation of TNF superfamily molecules release by neutrophils and B leukemic cells of patients with chronic B - cell lymphocytic leukemia. Neoplasma. vol 58. issue 1. 2011-08-04. PMID:21067265. |
the aim of our study was to evaluate the expression and release of baff (b-cell activating factor), april (a proliferation-inducing ligand) and trail (tnf-related apoptosis inducing ligand) molecules belonging to the cytokines of the superfamily of the tumor necrosis factor (tnf) by neutrophils (pmns) and, for comparison, b cells isolated from the blood of patients with b-cll vs. their concentration in the blood serum. |
2011-08-04 |
2023-08-12 |
human |
| Zhi-Chun Liu, Qiao-Ling Zhou, Xiao-Zhao Li, Jing-Hua Yang, Xiang Ao, Pouranan Veeraragoo, Xiao-Xia Zu. Elevation of human tumor necrosis factor-like weak inducer of apoptosis in peripheral blood mononuclear cells is correlated with disease activity and lupus nephritis in patients with systemic lupus erythematosus. Cytokine. vol 53. issue 3. 2011-07-22. PMID:21163672. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a recently identified proinflammatory cytokine of the tnf superfamily. |
2011-07-22 |
2023-08-12 |
human |
| Liping Xia, Hui Shen, Weiguo Xiao, Jing L. Increased serum TWEAK levels in Psoriatic arthritis: relationship with disease activity and matrix metalloproteinase-3 serum levels. Cytokine. vol 53. issue 3. 2011-07-22. PMID:21190865. |
we measured serum levels of tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak), interleukin 15 (il-15), monocyte chemoattractant protein 1 (mcp-1), and matrix metalloproteinase (mmp)-3 for patients with psoriatic arthritis (psa), and investigated whether tweak levels are associated with clinical disease activity and expression of proinflammatory cytokines. |
2011-07-22 |
2023-08-12 |
Not clear |
| Shogo Shimizu, Yasuhiro Yamada, Masataka Okuno, Hiroo Ohnishi, Yosuke Osawa, Mitsuru Seishima, Hisataka Moriwak. Liver injury induced by lipopolysaccharide is mediated by TNFR-1 but not by TNFR-2 or Fas in mice. Hepatology research : the official journal of the Japan Society of Hepatology. vol 31. issue 3. 2011-07-14. PMID:15715973. |
endotoxemia causes liver injury in which tumor necrosis factor (tnf)-alpha plays a significant role by inducing hepatic apoptosis. |
2011-07-14 |
2023-08-12 |
mouse |
| Shogo Shimizu, Yasuhiro Yamada, Masataka Okuno, Hiroo Ohnishi, Yosuke Osawa, Mitsuru Seishima, Hisataka Moriwak. Liver injury induced by lipopolysaccharide is mediated by TNFR-1 but not by TNFR-2 or Fas in mice. Hepatology research : the official journal of the Japan Society of Hepatology. vol 31. issue 3. 2011-07-14. PMID:15715973. |
we here examined if such apoptosis is strictly dependent on tnf-alpha and which type of tnf receptor (tnfr) is involved, employing tnfr-1- and -2-knockout mice. |
2011-07-14 |
2023-08-12 |
mouse |
| Jikun Zha, Hongbing Sh. Molecular mechanism of signaling by tumor necrosis factor. Science in China. Series C, Life sciences. vol 45. issue 2. 2011-07-14. PMID:18763070. |
tumor necrosis factor (tnf) is an important cytokine with multiple biological effects, including cell growth, differentiation, apoptosis, immune regulation and induction of inflammation. |
2011-07-14 |
2023-08-12 |
Not clear |
| Jikun Zha, Hongbing Sh. Molecular mechanism of signaling by tumor necrosis factor. Science in China. Series C, Life sciences. vol 45. issue 2. 2011-07-14. PMID:18763070. |
the major signal transduction pathways triggered by tnf include those that lead to apoptosis, activation of transcription factor nf-kappa b and protein kinase jnk. |
2011-07-14 |
2023-08-12 |
Not clear |
| Hoon Huh, Yong-Jik Lee, Jung-Hee Kim, Min-Ho Kong, Kwan-Young Song, Gun Cho. The Effects of TWEAK, Fn14, and TGF-beta1 on Degeneration of Human Intervertebral Disc. Journal of Korean Neurosurgical Society. vol 47. issue 1. 2011-07-14. PMID:20157375. |
the purpose of this study is to explain the effect and reciprocal action among tumor necrosis factor (tnf) like weak inducer of apoptosis (tweak), fibroblast growth factor-inducible 14 (fn14), and transforming growth factor-beta1 (tgf-beta1) on degeneration of human intervertebral disc (ivd). |
2011-07-14 |
2023-08-12 |
human |
| Martin Hausman. How bacteria-induced apoptosis of intestinal epithelial cells contributes to mucosal inflammation. International journal of inflammation. vol 2010. 2011-07-14. PMID:21188215. |
tumor necrosis factor (tnf) secreted after exposure to invasive bacteria induces both apoptosis and cell shedding. |
2011-07-14 |
2023-08-12 |
Not clear |
| Wei Qiu, Bin Wu, Xinwei Wang, Monica E Buchanan, Miguel D Regueiro, Douglas J Hartman, Robert E Schoen, Jian Yu, Lin Zhan. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. The Journal of clinical investigation. vol 121. issue 5. 2011-07-12. PMID:21490394. |
therapies that target the inflammatory cytokine tnf have been found to inhibit iec apoptosis in patients with ibd, although the mechanism of iec apoptosis remains unclear. |
2011-07-12 |
2023-08-12 |
mouse |
| Hongxia Li, Xiaoming Li, Xiaoping Gao, Xiuying L. [Induction of apoptosis by tumor necrosis factor receptors 2 transgene in human laryngeal squamous cacinoma in nude mice animal model]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. vol 23. issue 3. 2011-06-30. PMID:19452731. |
to investigate the effect of tumor necrosis factor receptors ii (tnfr ii) in vivo transgene with topical injection of tnf alpha in inducing apoptosis and cell killing of laryngeal squamous carcinoma in nude mice animal model. |
2011-06-30 |
2023-08-12 |
mouse |
| Ramesh M Ray, Shi Jin, Mitulkumar N Bavaria, Leonard R Johnso. Regulation of JNK activity in the apoptotic response of intestinal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology. vol 300. issue 5. 2011-06-28. PMID:21350193. |
we examined the course of jnk activation in response to a combination of tnf-α and cpt (tnf + cpt), which resulted in a three- to fourfold increase in apoptosis compared with cpt alone, indicating an amplification of apoptotic signaling pathways. |
2011-06-28 |
2023-08-12 |
Not clear |