| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie Devallière, Béatrice Charrea. The adaptor Lnk (SH2B3): an emerging regulator in vascular cells and a link between immune and inflammatory signaling. Biochemical pharmacology. vol 82. issue 10. 2011-12-16. PMID:21723852. |
in ec, lnk is a negative regulator of tnf signaling that reduce proinflammatory phenotype and prevent ec from apoptosis. |
2011-12-16 |
2023-08-12 |
Not clear |
| Byoungduck Park, Bokyung Sung, Vivek R Yadav, Madan M Chaturvedi, Bharat B Aggarwa. Triptolide, histone acetyltransferase inhibitor, suppresses growth and chemosensitizes leukemic cells through inhibition of gene expression regulated by TNF-TNFR1-TRADD-TRAF2-NIK-TAK1-IKK pathway. Biochemical pharmacology. vol 82. issue 9. 2011-12-16. PMID:21820422. |
this led to enhancement of apoptosis induced by tnf, taxol, and thalidomide by the diterpene and to suppression of tumor invasion. |
2011-12-16 |
2023-08-12 |
Not clear |
| G K Deb, S R Dey, J I Bang, S J Cho, H C Park, J G Lee, I K Kon. 9-cis retinoic acid improves developmental competence and embryo quality during in vitro maturation of bovine oocytes through the inhibition of oocyte tumor necrosis factor-α gene expression. Journal of animal science. vol 89. issue 9. 2011-12-14. PMID:21478451. |
moreover, 9-cis ra rescued (p < 0.001) development rates (24.5 ± 11.1 vs. 15.6 ± 9.0%), increased total cell number (124.6 ± 36.5 vs. 106.9 ± 31.1), and reduced apoptosis (5.8 ± 2.0 vs. 8.1 ± 3.1%) in blastocysts exposed to tnf-α (tnf group). |
2011-12-14 |
2023-08-12 |
cattle |
| Adrienne Chen, H Steven Seifer. Neisseria gonorrhoeae-mediated inhibition of apoptotic signalling in polymorphonuclear leukocytes. Infection and immunity. vol 79. issue 11. 2011-12-08. PMID:21844239. |
we developed and validated an hl-60 myeloid leukemia cell culture model for pmn infection and used both these cells and primary pmns to show that n. gonorrhoeae infection alone does not induce apoptosis and furthermore that n. gonorrhoeae can inhibit both spontaneous apoptosis and apoptosis induced by the intrinsic and extrinsic apoptosis inducers staurosporine (sts) and tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), respectively. |
2011-12-08 |
2023-08-12 |
human |
| Jennifer K Schroeder, Cherie A Kessler, Stuart Handwerge. Critical role for TWIST1 in the induction of human uterine decidualization. Endocrinology. vol 152. issue 11. 2011-12-08. PMID:21914771. |
the huf cells pretreated with the twist1 sirna also underwent less apoptosis during decidualization than the control cells, as evidenced by a 20% decrease in dna fragmentation (terminal deoxynucleotidyl transferase 2'-deoxyuridine, 5'-triphosphate nick end labeling assay) and a 43-48% decrease in caspase 3, bcl2-associated x protein, and tnf receptor superfamily member 6 mrna levels. |
2011-12-08 |
2023-08-12 |
human |
| Claudine Piérard-Franchimont, Gérald E Piérard, Pascale Quatresoo. Focus on skin cancer association and progression under TNF antagonist therapy. Expert opinion on biological therapy. vol 11. issue 9. 2011-12-06. PMID:21762036. |
results of some animal experiments have indicated that tnf acts both as a tumour promotor and an inductor of apoptosis. |
2011-12-06 |
2023-08-12 |
Not clear |
| Cecilia Garcia-Rudaz, Mauricio Dorfman, Srinivasa Nagalla, Konstantin Svechnikov, Olle Söder, Sergio R Ojeda, Gregory A Disse. Excessive ovarian production of nerve growth factor elicits granulosa cell apoptosis by setting in motion a tumor necrosis factor α/stathmin-mediated death signaling pathway. Reproduction (Cambridge, England). vol 142. issue 2. 2011-12-05. PMID:21646391. |
inhibiting tnf actions in vivo by administering a soluble tnf receptor prevented the increase in total and phosphorylated stmn1 production, as well as gc apoptosis in ngf-overproducing ovaries. |
2011-12-05 |
2023-08-12 |
mouse |
| Ling Su, Guangbo Liu, Xuexi Hao, Ning Zhong, Diansheng Zhong, Xiangguo Liu, Sunil Singha. Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. European journal of cancer (Oxford, England : 1990). vol 47. issue 16. 2011-12-05. PMID:21726997. |
we showed that pemetrexed induced apoptosis via up-regulation of death receptor 5 (dr5), an important death receptor for tumour necrosis factor (tnf)-related apoptosis inducing ligand (trail). |
2011-12-05 |
2023-08-12 |
human |
| T Chen, Z-P Guo, M-M Li, J-Y Li, X-Y Jiao, Y-H Zhang, H-J Li. Tumour necrosis factor-like weak inducer of apoptosis (TWEAK), an important mediator of endothelial inflammation, is associated with the pathogenesis of Henoch-Schonlein purpura. Clinical and experimental immunology. vol 166. issue 1. 2011-11-21. PMID:21762126. |
tumour necrosis factor-like weak inducer of apoptosis (tweak), a member of the tumour necrosis factor (tnf) family, has been implicated as a proinflammatory cytokine in many types of autoimmune and infectious diseases. |
2011-11-21 |
2023-08-12 |
human |
| Ulrike Luckey, Marcus Maurer, Talkea Schmidt, Nadine Lorenz, Beate Seebach, Martin Metz, Kerstin Steinbrin. T cell killing by tolerogenic dendritic cells protects mice from allergy. The Journal of clinical investigation. vol 121. issue 10. 2011-11-21. PMID:21881208. |
dc-derived tnf protected mice from contact allergy by inducing apoptosis in allergen-specific effector cd8⁺ t cells via tnf receptor 2 but did not contribute to the generation and function of the regulatory t cells associated with lzt. |
2011-11-21 |
2023-08-12 |
mouse |
| M D Cantley, D P Fairlie, P M Bartold, K D Rainsford, G T Le, A J Lucke, C A Holding, D R Hayne. Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro. Journal of cellular physiology. vol 226. issue 12. 2011-11-14. PMID:21344383. |
expression of mrna encoding for osteoclast genes including rank, calcitonin receptor (ctr), c-fos, tumur necrosis factor (tnf) receptor associated factor (traf)6, nuclear factor of activated t cells (nfatc1), interferon-β, tnf-like weak inducer of apoptosis (tweak), and osteoclast-associated receptor (oscar) were assessed. |
2011-11-14 |
2023-08-12 |
human |
| Yunying Chen, Sara Lind Enoksson, Catharina Johansson, Maria A Karlsson, Lena Lundeberg, Gunnar Nilsson, Annika Scheynius, Mikael C I Karlsso. The expression of BAFF, APRIL and TWEAK is altered in eczema skin but not in the circulation of atopic and seborrheic eczema patients. PloS one. vol 6. issue 7. 2011-11-09. PMID:21765951. |
the serum/plasma concentration of baff, april and a close tnf member tweak (tnf-like weak inducer of apoptosis) was measured by elisa. |
2011-11-09 |
2023-08-12 |
Not clear |
| Hong Zhou, John W Marks, Walter N Hittelman, Hideo Yagita, Lawrence H Cheung, Michael G Rosenblum, Jeffrey A Winkle. Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells. Molecular cancer therapeutics. vol 10. issue 7. 2011-11-03. PMID:21586630. |
tnf-like weak inducer of apoptosis (tweak) and fibroblast growth factor (fgf)-inducible 14 (fn14) are a tnf superfamily ligand-receptor pair involved in many cellular processes including proliferation, migration, differentiation, inflammation, and angiogenesis. |
2011-11-03 |
2023-08-12 |
mouse |
| Despina Smirlis, Ketty Soteriado. Trypanosomatid apoptosis: 'Apoptosis' without the canonical regulators. Virulence. vol 2. issue 3. 2011-10-19. PMID:21566464. |
a review of the present knowledge of trypanosomatid apoptosis points to the fact that these dying protozoa acquire common apoptotic morphological features as metazoan cells, although they lack many of the molecules accepted today as canonical apoptosis mediators (bcl-2 family members, caspases, tnf related family of receptors). |
2011-10-19 |
2023-08-12 |
Not clear |
| J Malyszko, P Przybylowski, J Malyszko, E Koc-Zorawska, M Mysliwie. Tumor necrosis factor-related apoptosis-inducing ligand is a marker of kidney function and inflammation in heart and kidney transplant recipients. Transplantation proceedings. vol 43. issue 5. 2011-10-14. PMID:21693293. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) was originally identified as the third member of the tnf superfamily to induce apoptosis. |
2011-10-14 |
2023-08-12 |
human |
| P Przybylowski, J S Malyszko, J Malyszk. Soluble tumor necrosis factor-like weak inducer of apoptosis plasma levels as a novel biomarker of endothelial function in prevalent orthotopic heart transplant recipients. Transplantation proceedings. vol 43. issue 5. 2011-10-14. PMID:21693297. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a member of the tnf superfamily of cytokines. |
2011-10-14 |
2023-08-12 |
Not clear |
| Valda C Hilliard, Mark R Frey, Peter J Dempsey, Richard M Peek, D Brent Pol. TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival. American journal of physiology. Gastrointestinal and liver physiology. vol 301. issue 2. 2011-10-12. PMID:21617117. |
in this study, we tested the hypothesis that tnf transactivates erbb4 through tnf-α converting enzyme (tace)-mediated ligand release and that this transactivation is necessary to protect colonic epithelial cells from cytokine-induced apoptosis. |
2011-10-12 |
2023-08-12 |
mouse |
| Valda C Hilliard, Mark R Frey, Peter J Dempsey, Richard M Peek, D Brent Pol. TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival. American journal of physiology. Gastrointestinal and liver physiology. vol 301. issue 2. 2011-10-12. PMID:21617117. |
we conclude that tnf transactivates erbb4 through tace-dependent hb-egf release, thus protecting colon epithelial cells from cytokine-induced apoptosis. |
2011-10-12 |
2023-08-12 |
mouse |
| Diana Londoño, Jenny Carvajal, Klemen Strle, Kwang S Kim, Diego Cadavi. IL-10 Prevents apoptosis of brain endothelium during bacteremia. Journal of immunology (Baltimore, Md. : 1950). vol 186. issue 12. 2011-10-07. PMID:21602495. |
hbmec apoptosis during exposure to a low number of bacteria was associated with downregulation of tnf and tnfaip3 and upregulation of bax. |
2011-10-07 |
2023-08-12 |
mouse |
| Thomas J Sayer. Targeting the extrinsic apoptosis signaling pathway for cancer therapy. Cancer immunology, immunotherapy : CII. vol 60. issue 8. 2011-10-04. PMID:21626033. |
the extrinsic apoptosis pathway is triggered by the binding of death ligands of the tumor necrosis factor (tnf) family to their appropriate death receptors (drs) on the cell surface. |
2011-10-04 |
2023-08-12 |
Not clear |