| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rafia S Al-Lamki, WanHua Lu, Sarah Finlay, Jason P Twohig, Eddie C Y Wang, Aviva M Tolkovsky, John R Bradle. DR3 signaling protects against cisplatin nephrotoxicity mediated by tumor necrosis factor. The American journal of pathology. vol 180. issue 4. 2012-07-25. PMID:22330679. |
moreover, tnf exacerbated, whereas tl1a reduced, cisplatin-induced apoptosis in the dr3(+/+) mouse proximal tubule cell line, tkpts. |
2012-07-25 |
2023-08-12 |
mouse |
| X-M Ding, Ke-Ying Zhang, L Wang, S-P Ba. Toxicity of melamine and cyanuric acid in broilers and residues in tissues. Human & experimental toxicology. vol 31. issue 2. 2012-07-24. PMID:22027504. |
on day 21, the uric acid (ua) content of group iv was increased in serum (p < 0.05); on day 42, the serum aspartate aminotransferase (ast) activity and the level of tumor necrosis factor (tnf)-α and interleukin (il)-8 increased in group iv (p < 0.05); 100 mg/kg mel alone increased the level of tnf-α and the rate of renal apoptosis (p < 0.05); and 33.3 mg/kg cya alone increased the level of il-8 and the rate of renal apoptosis (p < 0.05). |
2012-07-24 |
2023-08-12 |
Not clear |
| Zhi-Chun Liu, Qiao-Ling Zho. Tumor necrosis factor-like weak inducer of apoptosis and its potential roles in lupus nephritis. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. vol 61. issue 4. 2012-07-24. PMID:22297307. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a recently identified proinflammatory cytokine of the tnf superfamily that functions through binding to fn14 receptor in target cells. |
2012-07-24 |
2023-08-12 |
Not clear |
| Loris Zamai, Genny Del Zotto, Flavia Buccella, Laura Galeotti, Barbara Canonico, Francesca Luchetti, Stefano Pap. Cytotoxic functions and susceptibility to apoptosis of human CD56(bright) NK cells differentiated in vitro from CD34⁺ hematopoietic progenitors. Cytometry. Part A : the journal of the International Society for Analytical Cytology. vol 81. issue 4. 2012-07-24. PMID:22319021. |
our results suggest that during differentiation cd56(bright) nk cells, similarly to mature activated nk cells, become highly cytotoxic and are relatively resistant to apoptosis induced by tnf family members. |
2012-07-24 |
2023-08-12 |
human |
| Eugene Varfolomeev, Tatiana Goncharov, Heather Maecker, Kerry Zobel, László G Kömüves, Kurt Deshayes, Domagoj Vuci. Cellular inhibitors of apoptosis are global regulators of NF-κB and MAPK activation by members of the TNF family of receptors. Science signaling. vol 5. issue 216. 2012-07-09. PMID:22434933. |
cellular inhibitors of apoptosis are global regulators of nf-κb and mapk activation by members of the tnf family of receptors. |
2012-07-09 |
2023-08-12 |
Not clear |
| Bin Zhao, Lu Li, Kai Cui, Chang-Liang Wang, Ai-Liang Wang, Zi-Qiang Sun, Bo Zhang, Wu-Yuan Zhou, Zuo-Xing Niu, He Tian, Yan Xue, Sheng L. Mechanisms of TRAIL and gemcitabine induction of pancreatic cancer cell apoptosis. Asian Pacific journal of cancer prevention : APJCP. vol 12. issue 10. 2012-06-28. PMID:22320973. |
the aim of this study was to investigate induction of apoptosis by the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and gemcitabine in the pancreatic cancer cell line sw1990. |
2012-06-28 |
2023-08-12 |
Not clear |
| M Kadomatsu, S Nakajima, H Kato, L Gu, Y Chi, J Yao, M Kitamur. Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB. Clinical and experimental immunology. vol 168. issue 3. 2012-06-20. PMID:22519596. |
cordycepin as a sensitizer to tumour necrosis factor (tnf)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eif2α)- and mammalian target of rapamycin complex 1 (mtorc1)-mediated inhibition of nuclear factor (nf)-κb. |
2012-06-20 |
2023-08-12 |
Not clear |
| Chung Soo Lee, Eun-Ra Jang, Yun Jeong Kim, Soon Chul Myung, Wonyong Kim, Min Won Le. Diarylheptanoid hirsutenone enhances apoptotic effect of TRAIL on epithelial ovarian carcinoma cell lines via activation of death receptor and mitochondrial pathway. Investigational new drugs. vol 30. issue 2. 2012-06-11. PMID:21120579. |
tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) induces apoptosis in various cancer cells. |
2012-06-11 |
2023-08-12 |
human |
| Devalingam Mahalingam, Corina N A M Oldenhuis, Eva Szegezdi, Francis J Giles, Elisabeth G E de Vries, Steven de Jong, Steffan T Nawrock. Targeting TRAIL towards the clinic. Current drug targets. vol 12. issue 14. 2012-06-11. PMID:21777191. |
tumor necrosis factor-related apoptosis-inducing ligand or apo2 ligand (trail/apo2l) is a member of the tumor necrosis factor (tnf) superfamily that induces apoptosis upon binding to its death domain-containing transmembrane receptors. |
2012-06-11 |
2023-08-12 |
Not clear |
| Sophie S Chen, Agnieszka Michael, Simon A Butler-Manue. Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. Discovery medicine. vol 13. issue 68. 2012-06-11. PMID:22284780. |
additionally, most of these phytochemicals have been shown to stabilize p53 protein, sensitize trail (tnf receptor apoptosis-inducing ligand) induced apoptosis, and prevent or delay chemotherapy-resistance. |
2012-06-11 |
2023-08-12 |
Not clear |
| E N Gurzov, J Barthson, I Marhfour, F Ortis, N Naamane, M Igoillo-Esteve, C Gysemans, C Mathieu, S Kitajima, P Marchetti, T F Ørntoft, L Bakiri, E F Wagner, D L Eiziri. Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation. Oncogene. vol 31. issue 13. 2012-05-31. PMID:21841823. |
in vitro studies demonstrated that the cytokines tumor necrosis factor (tnf)-α and interferon (ifn)-γ induce junb expression as a protective mechanism against apoptosis in both human and rodent β-cells. |
2012-05-31 |
2023-08-12 |
mouse |
| Sandra Pacios, Jun Kang, Johnah Galicia, Kenneth Gluck, Hemal Patel, Amy Ovaydi-Mandel, Sophia Petrov, Faizan Alawi, Dana T Grave. Diabetes aggravates periodontitis by limiting repair through enhanced inflammation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 4. 2012-05-31. PMID:22179526. |
tnf inhibition in diabetic animals also reduced apoptosis, increased proliferation of bone-lining cells, and increased mrna levels of fgf-2, tgfβ-1, bmp-2, and bmp-6. |
2012-05-31 |
2023-08-12 |
rat |
| Sireesha V Garimella, Andrea Rocca, Stanley Lipkowit. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Molecular cancer research : MCR. vol 10. issue 1. 2012-05-24. PMID:22112940. |
trail is a member of the tnf super family and has been shown to induce apoptosis in many cancer cell lines but not in normal cells. |
2012-05-24 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
analysis of a number of chemopreventive and therapeutic agents reveal that hdac inhibitors are particularly adept at sensitizing colon cancer cells tnf or trail mediated apoptosis. |
2012-05-21 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
in vivo data are consistent with an interaction between saha and tnf in inducing apoptosis, as aom-induced colon tumors express elevated levels of tnf and are more sensitive to saha administration. |
2012-05-21 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
cell cycle analysis and time-lapse imaging indicated a close correspondence between saha-induced prophase arrest and tnf or trail-induced apoptosis. |
2012-05-21 |
2023-08-12 |
Not clear |
| Jie Zhao, Siriporn Jitkaew, Zhenyu Cai, Swati Choksi, Qiuning Li, Ji Luo, Zheng-Gang Li. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 14. 2012-05-21. PMID:22421439. |
tumor necrosis factor (tnf) is an important inflammatory cytokine and induces many cellular responses, including inflammation, cell proliferation, apoptosis, and necrosis. |
2012-05-21 |
2023-08-12 |
human |
| C Jennewein, S Karl, B Baumann, O Micheau, K-M Debatin, S Fuld. Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells. Oncogene. vol 31. issue 11. 2012-05-18. PMID:21822306. |
inhibition of nf-κb by overexpression of the dominant-negative iκbα-superrepressor (iκbα-sr) significantly decreases tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)- or cd95-induced apoptosis. |
2012-05-18 |
2023-08-12 |
Not clear |
| S Bhatnagar, A Kuma. The TWEAK-Fn14 system: breaking the silence of cytokine-induced skeletal muscle wasting. Current molecular medicine. vol 12. issue 1. 2012-05-18. PMID:22082477. |
an inflammatory cytokine, tumor necrosis factor (tnf)- like weak inducer of apoptosis (tweak), has recently been identified as a potent inducer of skeletal muscle wasting. |
2012-05-18 |
2023-08-12 |
Not clear |
| Ping Huang, M R Sandhya Rani, Manmeet S Ahluwalia, Eunnyung Bae, Richard A Prayson, Robert J Weil, Amy S Nowacki, Hirad Hedayat, Andrew E Sloan, Justin D Lathia, Jeremy N Rich, Russell Tipps, Candece L Gladso. Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma. Cancer research. vol 72. issue 6. 2012-05-14. PMID:22396498. |
activation of tnf receptor 1 (tnf-r1) can generate signals that promote either apoptosis or survival. |
2012-05-14 |
2023-08-12 |
Not clear |