| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bin Zhao, Lu Li, Kai Cui, Chang-Liang Wang, Ai-Liang Wang, Zi-Qiang Sun, Bo Zhang, Wu-Yuan Zhou, Zuo-Xing Niu, He Tian, Yan Xue, Sheng L. Mechanisms of TRAIL and gemcitabine induction of pancreatic cancer cell apoptosis. Asian Pacific journal of cancer prevention : APJCP. vol 12. issue 10. 2012-06-28. PMID:22320973. |
the aim of this study was to investigate induction of apoptosis by the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and gemcitabine in the pancreatic cancer cell line sw1990. |
2012-06-28 |
2023-08-12 |
Not clear |
| M Kadomatsu, S Nakajima, H Kato, L Gu, Y Chi, J Yao, M Kitamur. Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB. Clinical and experimental immunology. vol 168. issue 3. 2012-06-20. PMID:22519596. |
cordycepin as a sensitizer to tumour necrosis factor (tnf)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eif2α)- and mammalian target of rapamycin complex 1 (mtorc1)-mediated inhibition of nuclear factor (nf)-κb. |
2012-06-20 |
2023-08-12 |
Not clear |
| Chung Soo Lee, Eun-Ra Jang, Yun Jeong Kim, Soon Chul Myung, Wonyong Kim, Min Won Le. Diarylheptanoid hirsutenone enhances apoptotic effect of TRAIL on epithelial ovarian carcinoma cell lines via activation of death receptor and mitochondrial pathway. Investigational new drugs. vol 30. issue 2. 2012-06-11. PMID:21120579. |
tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) induces apoptosis in various cancer cells. |
2012-06-11 |
2023-08-12 |
human |
| Devalingam Mahalingam, Corina N A M Oldenhuis, Eva Szegezdi, Francis J Giles, Elisabeth G E de Vries, Steven de Jong, Steffan T Nawrock. Targeting TRAIL towards the clinic. Current drug targets. vol 12. issue 14. 2012-06-11. PMID:21777191. |
tumor necrosis factor-related apoptosis-inducing ligand or apo2 ligand (trail/apo2l) is a member of the tumor necrosis factor (tnf) superfamily that induces apoptosis upon binding to its death domain-containing transmembrane receptors. |
2012-06-11 |
2023-08-12 |
Not clear |
| Sophie S Chen, Agnieszka Michael, Simon A Butler-Manue. Advances in the treatment of ovarian cancer: a potential role of antiinflammatory phytochemicals. Discovery medicine. vol 13. issue 68. 2012-06-11. PMID:22284780. |
additionally, most of these phytochemicals have been shown to stabilize p53 protein, sensitize trail (tnf receptor apoptosis-inducing ligand) induced apoptosis, and prevent or delay chemotherapy-resistance. |
2012-06-11 |
2023-08-12 |
Not clear |
| E N Gurzov, J Barthson, I Marhfour, F Ortis, N Naamane, M Igoillo-Esteve, C Gysemans, C Mathieu, S Kitajima, P Marchetti, T F Ørntoft, L Bakiri, E F Wagner, D L Eiziri. Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation. Oncogene. vol 31. issue 13. 2012-05-31. PMID:21841823. |
in vitro studies demonstrated that the cytokines tumor necrosis factor (tnf)-α and interferon (ifn)-γ induce junb expression as a protective mechanism against apoptosis in both human and rodent β-cells. |
2012-05-31 |
2023-08-12 |
mouse |
| Sandra Pacios, Jun Kang, Johnah Galicia, Kenneth Gluck, Hemal Patel, Amy Ovaydi-Mandel, Sophia Petrov, Faizan Alawi, Dana T Grave. Diabetes aggravates periodontitis by limiting repair through enhanced inflammation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 26. issue 4. 2012-05-31. PMID:22179526. |
tnf inhibition in diabetic animals also reduced apoptosis, increased proliferation of bone-lining cells, and increased mrna levels of fgf-2, tgfβ-1, bmp-2, and bmp-6. |
2012-05-31 |
2023-08-12 |
rat |
| Sireesha V Garimella, Andrea Rocca, Stanley Lipkowit. WEE1 inhibition sensitizes basal breast cancer cells to TRAIL-induced apoptosis. Molecular cancer research : MCR. vol 10. issue 1. 2012-05-24. PMID:22112940. |
trail is a member of the tnf super family and has been shown to induce apoptosis in many cancer cell lines but not in normal cells. |
2012-05-24 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
analysis of a number of chemopreventive and therapeutic agents reveal that hdac inhibitors are particularly adept at sensitizing colon cancer cells tnf or trail mediated apoptosis. |
2012-05-21 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
in vivo data are consistent with an interaction between saha and tnf in inducing apoptosis, as aom-induced colon tumors express elevated levels of tnf and are more sensitive to saha administration. |
2012-05-21 |
2023-08-12 |
Not clear |
| Anton Kuratnik, Virginia E Senapati, Rajeev Verma, Barbara G Mellone, Anthony T Vella, Charles Giardin. Acute sensitization of colon cancer cells to inflammatory cytokines by prophase arrest. Biochemical pharmacology. vol 83. issue 9. 2012-05-21. PMID:22306067. |
cell cycle analysis and time-lapse imaging indicated a close correspondence between saha-induced prophase arrest and tnf or trail-induced apoptosis. |
2012-05-21 |
2023-08-12 |
Not clear |
| Jie Zhao, Siriporn Jitkaew, Zhenyu Cai, Swati Choksi, Qiuning Li, Ji Luo, Zheng-Gang Li. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 14. 2012-05-21. PMID:22421439. |
tumor necrosis factor (tnf) is an important inflammatory cytokine and induces many cellular responses, including inflammation, cell proliferation, apoptosis, and necrosis. |
2012-05-21 |
2023-08-12 |
human |
| C Jennewein, S Karl, B Baumann, O Micheau, K-M Debatin, S Fuld. Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells. Oncogene. vol 31. issue 11. 2012-05-18. PMID:21822306. |
inhibition of nf-κb by overexpression of the dominant-negative iκbα-superrepressor (iκbα-sr) significantly decreases tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)- or cd95-induced apoptosis. |
2012-05-18 |
2023-08-12 |
Not clear |
| S Bhatnagar, A Kuma. The TWEAK-Fn14 system: breaking the silence of cytokine-induced skeletal muscle wasting. Current molecular medicine. vol 12. issue 1. 2012-05-18. PMID:22082477. |
an inflammatory cytokine, tumor necrosis factor (tnf)- like weak inducer of apoptosis (tweak), has recently been identified as a potent inducer of skeletal muscle wasting. |
2012-05-18 |
2023-08-12 |
Not clear |
| Ping Huang, M R Sandhya Rani, Manmeet S Ahluwalia, Eunnyung Bae, Richard A Prayson, Robert J Weil, Amy S Nowacki, Hirad Hedayat, Andrew E Sloan, Justin D Lathia, Jeremy N Rich, Russell Tipps, Candece L Gladso. Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma. Cancer research. vol 72. issue 6. 2012-05-14. PMID:22396498. |
activation of tnf receptor 1 (tnf-r1) can generate signals that promote either apoptosis or survival. |
2012-05-14 |
2023-08-12 |
Not clear |
| Andrea Fick, Isabell Lang, Viktoria Schäfer, Axel Seher, Johannes Trebing, Daniela Weisenberger, Harald Wajan. Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor inducible 14 (Fn14). The Journal of biological chemistry. vol 287. issue 1. 2012-05-08. PMID:22081603. |
studies of binding of tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) to fibroblast growth factor inducible 14 (fn14). |
2012-05-08 |
2023-08-12 |
human |
| Masako Yoshimatsu, Hideki Kitaura, Yuji Fujimura, Haruka Kohara, Yukiko Morita, Toshiko Eguchi, Noriaki Yoshid. Inhibitory effects of IL-12 on experimental tooth movement and root resorption in mice. Archives of oral biology. vol 57. issue 1. 2012-05-04. PMID:21821230. |
we previously reported that il-12 inhibits tumour necrosis factor (tnf)-α-mediated osteoclast formation by inducing apoptosis. |
2012-05-04 |
2023-08-12 |
mouse |
| Cheol Park, Cheng-Yun Jin, Hye Jin Hwang, Gi-Young Kim, Jee H Jung, Wun-Jae Kim, Young Hyun Yoo, Yung Hyun Cho. J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 26. issue 1. 2012-05-03. PMID:22079975. |
the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail/apo2l), a member of the tnf gene superfamily, induces apoptosis upon engagement of cognate death receptors. |
2012-05-03 |
2023-08-12 |
human |
| Sally-Anne Heasman, Lyubov Zaitseva, Kristian M Bowles, Stuart A Rushworth, David J Macewa. Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1. Oncotarget. vol 2. issue 9. 2012-05-01. PMID:21911919. |
recently, we showed that ho-1 protects aml samples from tumour necrosis factor-α (tnf)-induced apoptosis - it being regulated by transcription factors nrf2, nf-ĸb and ap-1. |
2012-05-01 |
2023-08-12 |
human |
| Fumiko Honda, Hirotsugu Kano, Hirokazu Kanegane, Shigeaki Nonoyama, Eun-Sung Kim, Sang-Kyou Lee, Masatoshi Takagi, Shuki Mizutani, Tomohiro Mori. The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils. Nature immunology. vol 13. issue 4. 2012-05-01. PMID:22366891. |
here we found that btk-deficient neutrophils had more production of reactive oxygen species (ros) after engagement of toll-like receptors (tlrs) or receptors for tumor-necrosis factor (tnf), which was associated with more apoptosis and was reversed by transduction of recombinant btk. |
2012-05-01 |
2023-08-12 |
human |