| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xin-Qiu Li, Xian-Zhu Ke, Yu-Ming Wan. Treatment of malignant melanoma by downregulation of XIAP and overexpression of TRAIL with a conditionally replicating oncolytic adenovirus. Asian Pacific journal of cancer prevention : APJCP. vol 13. issue 4. 2013-01-30. PMID:22799350. |
the tumor necrosis factor (tnf)- related apoptosis-inducing ligand has a significant impact on therapy for patients with x-linked inhibitor of apoptosis protein-downregulation malignant melanoma. |
2013-01-30 |
2023-08-12 |
Not clear |
| G L Robinson, D Dinsdale, M Macfarlane, K Cai. Switching from aerobic glycolysis to oxidative phosphorylation modulates the sensitivity of mantle cell lymphoma cells to TRAIL. Oncogene. vol 31. issue 48. 2013-01-29. PMID:22310286. |
trail (tnf (tumour necrosis factor)-related apoptosis-inducing ligand) a putative anti-cancer cytokine induces apoptosis through disc (death-inducing signalling complex)-mediated activation of caspase-8 and/or cleavage of bid. |
2013-01-29 |
2023-08-12 |
Not clear |
| O M Andriankaja, J Galicia, G Dong, W Xiao, F Alawi, D T Grave. Gene expression dynamics during diabetic periodontitis. Journal of dental research. vol 91. issue 12. 2013-01-29. PMID:23103632. |
others were down-regulated by tnf inhibition and included genes associated with host defense, apoptosis, cell signaling and activity, and coagulation/hemostasis/complement. |
2013-01-29 |
2023-08-12 |
rat |
| Ashish Nagarsekar, Mohan E Tulapurkar, Ishwar S Singh, Sergei P Atamas, Nirav G Shah, Jeffrey D Hasda. Hyperthermia promotes and prevents respiratory epithelial apoptosis through distinct mechanisms. American journal of respiratory cell and molecular biology. vol 47. issue 6. 2013-01-25. PMID:22962066. |
exposing mle15 cells to heat shock (hs; 42°c, 2 h) or febrile-range hyperthermia (39.5°c) concurrent with activation of the death receptors, tnf receptor 1 or fas, greatly accelerated apoptosis, which was detectable within 30 minutes and was associated with accelerated activation of caspase-2, -8, and -10, and the proapoptotic protein, bcl2-interacting domain (bid). |
2013-01-25 |
2023-08-12 |
mouse |
| Nataly Shulga, John G Pastorin. GRIM-19-mediated translocation of STAT3 to mitochondria is necessary for TNF-induced necroptosis. Journal of cell science. vol 125. issue Pt 12. 2013-01-24. PMID:22393233. |
tumor necrosis factor (tnf) can induce necroptosis, wherein inhibition of caspase activity prevents apoptosis but initiates an alternative programmed necrosis. |
2013-01-24 |
2023-08-12 |
Not clear |
| Irina T Nizamutdinova, Rakeshwar S Guleria, Amar B Singh, Jonathan A Kendall, Kenneth M Baker, Jing Pa. Retinoic acid protects cardiomyocytes from high glucose-induced apoptosis through inhibition of NF-κB signaling pathway. Journal of cellular physiology. vol 228. issue 2. 2013-01-24. PMID:22718360. |
activated nf-κb signaling has an important role in hg-induced cardiomyocyte apoptosis and gene expression of interleukin-6 (il-6), tumor necrosis factor (tnf)-α, and monocyte chemoattractant protein-1 (mcp-1). |
2013-01-24 |
2023-08-12 |
rat |
| Dimitrios Makrygiannakis, Anca Irinel Catrin. Apoptosis as a mechanism of action of tumor necrosis factor antagonists in rheumatoid arthritis. The Journal of rheumatology. vol 39. issue 4. 2013-01-22. PMID:22422498. |
one unresolved issue is to what extent apoptosis is affected by tnf blockade in ra. |
2013-01-22 |
2023-08-12 |
Not clear |
| Kathrin Steinwede, Stefanie Henken, Jennifer Bohling, Regina Maus, Bianca Ueberberg, Christina Brumshagen, Erik L Brincks, Thomas S Griffith, Tobias Welte, Ulrich A Mau. TNF-related apoptosis-inducing ligand (TRAIL) exerts therapeutic efficacy for the treatment of pneumococcal pneumonia in mice. The Journal of experimental medicine. vol 209. issue 11. 2013-01-18. PMID:23071253. |
here, we examined the role of the tnf superfamily member tnf-related apoptosis-inducing ligand (trail) in s. pneumoniae-induced macrophage apoptosis, and investigated the potential benefit of trail-based therapy during pneumococcal pneumonia in mice. |
2013-01-18 |
2023-08-12 |
mouse |
| Brian W C Tse, Kieran F Scott, Pamela J Russel. Paradoxical roles of tumour necrosis factor-alpha in prostate cancer biology. Prostate cancer. vol 2012. 2013-01-18. PMID:23326670. |
on the other hand, tnf has also been reported to inhibit neovascularisation, induce apoptosis of pca cells, and stimulate antitumour immunity. |
2013-01-18 |
2023-08-12 |
Not clear |
| Christian Winkel, Simon Neumann, Christina Surulescu, Peter Scheuric. A minimal mathematical model for the initial molecular interactions of death receptor signalling. Mathematical biosciences and engineering : MBE. vol 9. issue 3. 2013-01-10. PMID:22881031. |
a subgroup of the tnf ligand family, including tnf, signals via so-called death receptors, capable to induce a major form of programmed cell death, called apoptosis. |
2013-01-10 |
2023-08-12 |
Not clear |
| Mingxing Lei, Xiufeng Bai, Tian Yang, Xiangdong Lai, Weiming Qiu, Li Yang, Xiaohua Lia. Gsdma3 is a new factor needed for TNF-α-mediated apoptosis signal pathway in mouse skin keratinocytes. Histochemistry and cell biology. vol 138. issue 3. 2013-01-07. PMID:22585037. |
apoptosis of skin keratinocytes is strictly regulated by a series of signal pathways, among of which, tumor necrosis factor (tnf)-α-induced signal pathway has been extensively studied. |
2013-01-07 |
2023-08-12 |
mouse |
| R Savanh Chanthaphavong, Patricia A Loughran, Tiffany Y S Lee, Melanie J Scott, Timothy R Billia. A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes. The Journal of biological chemistry. vol 287. issue 43. 2012-12-28. PMID:22898814. |
in vitro, hepatocytes are protected from tumor necrosis factor (tnf) α-induced apoptosis via cgmp-dependent and cgmp-independent mechanisms. |
2012-12-28 |
2023-08-12 |
Not clear |
| Fangmei An, Bangdong Gong, Hui Wang, Dongshan Yu, Gangde Zhao, Lanyi Lin, Weiliang Tang, Hong Yu, Shisan Bao, Qing Xi. miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. Apoptosis : an international journal on programmed cell death. vol 17. issue 7. 2012-12-21. PMID:22374434. |
mir-15b and mir-16 regulate tnf mediated hepatocyte apoptosis via bcl2 in acute liver failure. |
2012-12-21 |
2023-08-12 |
Not clear |
| Fangmei An, Bangdong Gong, Hui Wang, Dongshan Yu, Gangde Zhao, Lanyi Lin, Weiliang Tang, Hong Yu, Shisan Bao, Qing Xi. miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. Apoptosis : an international journal on programmed cell death. vol 17. issue 7. 2012-12-21. PMID:22374434. |
inhibition of mir-15b and/or mir-16 reduced hepatic apoptosis and tnf production. |
2012-12-21 |
2023-08-12 |
Not clear |
| Fangmei An, Bangdong Gong, Hui Wang, Dongshan Yu, Gangde Zhao, Lanyi Lin, Weiliang Tang, Hong Yu, Shisan Bao, Qing Xi. miR-15b and miR-16 regulate TNF mediated hepatocyte apoptosis via BCL2 in acute liver failure. Apoptosis : an international journal on programmed cell death. vol 17. issue 7. 2012-12-21. PMID:22374434. |
these data suggest that mir-15b and mir-16 regulate tnf mediated hepatic apoptosis via bcl2 during alf, and may shed light on the development of a therapeutic strategy for treatment of alf. |
2012-12-21 |
2023-08-12 |
Not clear |
| J Jurgensmeier, P Hofler, G Baue. Tgf-Beta-induced apoptosis of transformed fibroblasts by normal fibroblasts - independence of cell-to-cell contact and dependence on reactive oxygen species. International journal of oncology. vol 5. issue 3. 2012-12-20. PMID:21559608. |
kinetic experiments revealed two steps: first, the elimination process is induced in the normal cells by tgf-beta and later, the apoptosis of transformed cells is mediated by a short-lived effector different from tgf-beta and tnf. |
2012-12-20 |
2023-08-12 |
Not clear |
| Laura E White, Yan Cui, Carolyn M Feltes Shelak, Mihaela L Lie, Heitham T Hassou. Lung endothelial cell apoptosis during ischemic acute kidney injury. Shock (Augusta, Ga.). vol 38. issue 3. 2012-12-14. PMID:22777112. |
rat lung microvascular ecs treated +/- etanercept, a tnf-α/tnfr1 signaling inhibitor, underwent custom real-time polymerase chain reaction analysis for proapoptotic and tnf superfamily transcriptional events, and apoptosis was identified with caspase 3 and poly(adp-ribose) polymerase activity assays. |
2012-12-14 |
2023-08-12 |
mouse |
| Rachita K Sumbria, Ruben J Boado, William M Pardridg. Brain protection from stroke with intravenous TNFα decoy receptor-Trojan horse fusion protein. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 32. issue 10. 2012-12-11. PMID:22714051. |
tumor necrosis factor (tnf)-α is produced in brain in response to acute cerebral ischemia, and promotes neuronal apoptosis. |
2012-12-11 |
2023-08-12 |
mouse |
| Regina Golan-Gerstl, Shulamit B Wallach-Dayan, Philip Zisman, Wellington V Cardoso, Ronald H Goldstein, Raphael Breue. Cellular FLICE-like inhibitory protein deviates myofibroblast fas-induced apoptosis toward proliferation during lung fibrosis. American journal of respiratory cell and molecular biology. vol 47. issue 3. 2012-11-30. PMID:22582174. |
using the animal model, we show that fibrotic lung myofibroblasts divert fas signaling from apoptosis to proliferation and that this requires signaling by tnf receptor-associated factor (traf) and nf-κb. |
2012-11-30 |
2023-08-12 |
mouse |
| Aleksandra Mielczarek-Palacz, Zdzisława Kondera-Anasz, Justyna Sikor. Higher serum levels of tumour necrosis factor and its soluble receptors are associated with ovarian tumours. Archives of medical science : AMS. vol 8. issue 5. 2012-11-28. PMID:23185194. |
tumour necrosis factor (tnf) and its soluble receptors type 1 (stnf-r1) and type 2 (stnf-r2) have been suggested as key mediators between apoptosis and cancer cell progression. |
2012-11-28 |
2023-08-12 |
Not clear |