| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrea Fick, Isabell Lang, Viktoria Schäfer, Axel Seher, Johannes Trebing, Daniela Weisenberger, Harald Wajan. Studies of binding of tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) to fibroblast growth factor inducible 14 (Fn14). The Journal of biological chemistry. vol 287. issue 1. 2012-05-08. PMID:22081603. |
studies of binding of tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) to fibroblast growth factor inducible 14 (fn14). |
2012-05-08 |
2023-08-12 |
human |
| Masako Yoshimatsu, Hideki Kitaura, Yuji Fujimura, Haruka Kohara, Yukiko Morita, Toshiko Eguchi, Noriaki Yoshid. Inhibitory effects of IL-12 on experimental tooth movement and root resorption in mice. Archives of oral biology. vol 57. issue 1. 2012-05-04. PMID:21821230. |
we previously reported that il-12 inhibits tumour necrosis factor (tnf)-α-mediated osteoclast formation by inducing apoptosis. |
2012-05-04 |
2023-08-12 |
mouse |
| Cheol Park, Cheng-Yun Jin, Hye Jin Hwang, Gi-Young Kim, Jee H Jung, Wun-Jae Kim, Young Hyun Yoo, Yung Hyun Cho. J7, a methyl jasmonate derivative, enhances TRAIL-mediated apoptosis through up-regulation of reactive oxygen species generation in human hepatoma HepG2 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 26. issue 1. 2012-05-03. PMID:22079975. |
the tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail/apo2l), a member of the tnf gene superfamily, induces apoptosis upon engagement of cognate death receptors. |
2012-05-03 |
2023-08-12 |
human |
| Sally-Anne Heasman, Lyubov Zaitseva, Kristian M Bowles, Stuart A Rushworth, David J Macewa. Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1. Oncotarget. vol 2. issue 9. 2012-05-01. PMID:21911919. |
recently, we showed that ho-1 protects aml samples from tumour necrosis factor-α (tnf)-induced apoptosis - it being regulated by transcription factors nrf2, nf-ĸb and ap-1. |
2012-05-01 |
2023-08-12 |
human |
| Fumiko Honda, Hirotsugu Kano, Hirokazu Kanegane, Shigeaki Nonoyama, Eun-Sung Kim, Sang-Kyou Lee, Masatoshi Takagi, Shuki Mizutani, Tomohiro Mori. The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils. Nature immunology. vol 13. issue 4. 2012-05-01. PMID:22366891. |
here we found that btk-deficient neutrophils had more production of reactive oxygen species (ros) after engagement of toll-like receptors (tlrs) or receptors for tumor-necrosis factor (tnf), which was associated with more apoptosis and was reversed by transduction of recombinant btk. |
2012-05-01 |
2023-08-12 |
human |
| Jiro Yamana, Eric F Morand, Tsuno Manabu, Katsue Sunahori, Kouji Takasugi, Hirofumi Makino, Masahiro Yamamur. Inhibition of TNF-induced IL-6 by the TWEAK-Fn14 interaction in rheumatoid arthritis fibroblast like synoviocytes. Cellular immunology. vol 272. issue 2. 2012-04-30. PMID:22055894. |
tnf-like weak inducer of apoptosis (tweak), a member of the tnf superfamily, has been shown to increase cytokine production by rheumatoid arthritis (ra) fibroblast-like synoviocytes (fls). |
2012-04-30 |
2023-08-12 |
Not clear |
| Chung-Ting Tsai, Kazuya Ikematsu, Sayaka Sakai, Aya Matsuo, Ichiro Nakason. Expression of Bcl2l1, Clcf1, IL-28ra and Pias1 in the mouse heart after single and repeated administration of chlorpromazine. Legal medicine (Tokyo, Japan). vol 13. issue 5. 2012-04-11. PMID:21683644. |
after stimulation of tnf, the janus kinase signal transducer and activator of transcription (jak-stat) signaling pathway is activated via tnf receptor (tnf-r), and the pathway participates in the regulation of cellular responses such as apoptosis [1]. |
2012-04-11 |
2023-08-12 |
mouse |
| N Vanlangenakker, M J M Bertrand, P Bogaert, P Vandenabeele, T Vanden Bergh. TNF-induced necroptosis in L929 cells is tightly regulated by multiple TNFR1 complex I and II members. Cell death & disease. vol 2. 2012-04-10. PMID:22089168. |
we previously reported that cellular inhibitor of apoptosis protein-mediated receptor-interacting protein 1 (rip1) ubiquitination acts as a cytoprotective mechanism, whereas knockdown of cylindromatosis, a rip1-deubiquitinating enzyme, protects against tumor necrosis factor (tnf)-induced necroptosis. |
2012-04-10 |
2023-08-12 |
Not clear |
| Alberto Anel, Luis Martinez-Losta. APO2L/TRAIL: new insights in the treatment of autoimmune disorders. Recent patents on inflammation & allergy drug discovery. vol 5. issue 3. 2012-04-06. PMID:21827400. |
apo2 ligand/tnf related apoptosis-inducing ligand (apo2l/trail) is a cytokine that belongs to the tnf superfamilily that was described as capable of inducing apoptosis on tumor cells through activation of the extrinsic pathway in a fas-independent manner. |
2012-04-06 |
2023-08-12 |
Not clear |
| Fabrice Moore, Daniel A Cunha, Hindrik Mulder, Decio L Eiziri. Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells. Methods in molecular biology (Clifton, N.J.). vol 820. 2012-03-28. PMID:22131032. |
in vitro exposure of beta cells to the cytokines interleukin(il)-1β + interferon(ifn)-γ or to tumor necrosis factor(tnf)-α + ifn-γ induces beta cell dysfunction and ultimately apoptosis. |
2012-03-28 |
2023-08-12 |
Not clear |
| Yoko Ishimoto, Hideo Satsu, Mamoru Totsuka, Makoto Shimiz. IEX-1 suppresses apoptotic damage in human intestinal epithelial Caco-2 cells induced by co-culturing with macrophage-like THP-1 cells. Bioscience reports. vol 31. issue 5. 2012-03-26. PMID:21250941. |
increases in caspase 3 activity and tnfr1 (tnf receptor 1) mrna expression were shown in iex-1-knockdown caco-2 cells, suggesting that iex-1 plays a role in the suppression of apoptosis and protects cells by controlling sensitivity to tnfα under both normal and inflammatory conditions. |
2012-03-26 |
2023-08-12 |
human |
| Kyung-Jin Park, Chang-Han Lee, Aeyung Kim, Ki Jun Jeong, Chul-Ho Kim, Yong-Sung Ki. Death receptors 4 and 5 activate Nox1 NADPH oxidase through riboflavin kinase to induce reactive oxygen species-mediated apoptotic cell death. The Journal of biological chemistry. vol 287. issue 5. 2012-03-22. PMID:22158615. |
stimulation of the proapoptotic tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) receptors, death receptors 4 (dr4) and 5 (dr5), conventionally induces caspase-dependent apoptosis in tumor cells. |
2012-03-22 |
2023-08-12 |
human |
| R Yerbes, C Palacios, A López-Riva. The therapeutic potential of TRAIL receptor signalling in cancer cells. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. vol 13. issue 12. 2012-03-20. PMID:22126726. |
the tumour necrosis-related apoptosisinducing ligand (trail) is a member of the tnf family capable of inducing apoptosis in a wide variety of cancer cells upon binding to pro-apoptotic receptors, while having no effect on the majority of normal human cells tested. |
2012-03-20 |
2023-08-12 |
mouse |
| Bharat B Aggarwal, Subash C Gupta, Ji Hye Ki. Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey. Blood. vol 119. issue 3. 2012-03-13. PMID:22053109. |
the roles of the tnf superfamily in inflammation, apoptosis, proliferation, invasion, angiogenesis, metastasis, and morphogenesis have been documented. |
2012-03-13 |
2023-08-12 |
Not clear |
| Joan Fernando, Patricia Sancho, Conrado M Fernández-Rodriguez, José L Lledó, Laia Caja, Jean S Campbell, Nelson Fausto, Isabel Fabrega. Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. Journal of cellular physiology. vol 227. issue 4. 2012-03-05. PMID:21604268. |
interestingly, sensitization to sorafenib-induced apoptosis is characteristic of liver tumor cells, since untransformed hepatocytes did not respond to sorafenib inducing apoptosis, either alone or in combination with tgf-β or tnf. |
2012-03-05 |
2023-08-12 |
human |
| I Ikonomidis, S Tzortzis, J Lekakis, I Paraskevaidis, P Dasou, J Parissis, M Nikolaou, S L Markantonis, P Katsimbri, G Skarantavos, I Andreadou, M Anastasiou-Nan. Association of soluble apoptotic markers with impaired left ventricular deformation in patients with rheumatoid arthritis. Effects of inhibition of interleukin-1 activity by anakinra. Thrombosis and haemostasis. vol 106. issue 5. 2012-02-29. PMID:21947196. |
at baseline, 3 h and 30 days after treatment, we measured circulating il-1β, tumour necrosis factor (tnf)-α, fas, fas-ligand and caspase-9 to assess apoptosis. |
2012-02-29 |
2023-08-12 |
Not clear |
| Andreas Kerstan, E-B Bröcker, A Trautman. Decisive role of tumor necrosis factor-α for spongiosis formation in acute eczematous dermatitis. Archives of dermatological research. vol 303. issue 9. 2012-02-24. PMID:21553284. |
as compared to cd95-triggering alone, synchronous cd95 and tnf receptor cross-linking in the presence of ifn-γ only marginally enhanced kc apoptosis. |
2012-02-24 |
2023-08-12 |
human |
| Carlo V Hojilla, Hartland W Jackson, Rama Khokh. TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence. PloS one. vol 6. issue 10. 2012-02-24. PMID:22053204. |
timp3 regulates mammary epithelial apoptosis with immune cell recruitment through differential tnf dependence. |
2012-02-24 |
2023-08-12 |
mouse |
| Carlo V Hojilla, Hartland W Jackson, Rama Khokh. TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence. PloS one. vol 6. issue 10. 2012-02-24. PMID:22053204. |
here we show that timp3 deficiency leads to tnf dysregulation, earlier caspase activation and onset of mitochondrial apoptosis. |
2012-02-24 |
2023-08-12 |
mouse |
| Carlo V Hojilla, Hartland W Jackson, Rama Khokh. TIMP3 regulates mammary epithelial apoptosis with immune cell recruitment through differential TNF dependence. PloS one. vol 6. issue 10. 2012-02-24. PMID:22053204. |
the data indicate that timp3 differentially impacts apoptosis and inflammatory cell influx, based on involvement of tnf, during the process of mammary involution. |
2012-02-24 |
2023-08-12 |
mouse |