| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| [Polymorphism of TNF gene and CPOX gene in chemical industry workers]. Meditsina truda i promyshlennaia ekologiia. issue 11. 2012-02-23. PMID:22288185. |
findings are peculiarities of genetic polymorphism of cpox gene and tnf gene, and their association with biologic media contamination with methylated phenols (m-cresol) and apoptosis disorders. |
2012-02-23 |
2023-08-12 |
Not clear |
| Woe Yeon Kim, Sun Yong Lee, Young Jun Jung, Ho Byoung Chae, Ganesh M Nawkar, Mi Rim Shin, Sun Young Kim, Jin Ho Park, Chang Ho Kang, Yong Hun Chi, Il Pyung Ahn, Dae Jin Yun, Kyun Oh Lee, Young-Myeong Kim, Min Gab Kim, Sang Yeol Le. Inhibitor of apoptosis (IAP)-like protein lacks a baculovirus IAP repeat (BIR) domain and attenuates cell death in plant and animal systems. The Journal of biological chemistry. vol 286. issue 49. 2012-02-21. PMID:21926169. |
the expression of atilp in hela cells conferred resistance against tumor necrosis factor (tnf)-α/actd-induced apoptosis through the inactivation of caspase activity. |
2012-02-21 |
2023-08-12 |
Not clear |
| Yingying Li, Lin Wan, Hao Yang, Shan Liu, Huawei Cai, Xiaofeng L. [Cloning and recombinant expression of human soluble TRAIL in Pichia pastoris]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 27. issue 6. 2012-02-16. PMID:21374984. |
tnf-related apoptosis-inducing ligand (trail) is a member of factor tnf family, which could be potentially developed as novel antitumor agent due to its selective and efficient induction of apoptosis in tumor cells. |
2012-02-16 |
2023-08-12 |
human |
| Linda C Burkly, Jennifer S Michaelson, Timothy S Zhen. TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses. Immunological reviews. vol 244. issue 1. 2012-02-09. PMID:22017434. |
while much of the molecular basis underlying the immune regulation of tissue responses remains to be delineated, the tumor necrosis factor (tnf) superfamily ligand/receptor pair of tnf-like weak inducer of apoptosis (tweak) and fibroblast growth factor-inducible molecule 14 (fn14) has now emerged as a key piece of this puzzle. |
2012-02-09 |
2023-08-12 |
Not clear |
| Raja Atreya, Michael Zimmer, Brigitte Bartsch, Maximilian J Waldner, Imke Atreya, Helmut Neumann, Kai Hildner, Arthur Hoffman, Ralf Kiesslich, Andreas D Rink, Tilman T Rau, Stefan Rose-John, Hermann Kessler, Jan Schmidt, Markus F Neurat. Antibodies against tumor necrosis factor (TNF) induce T-cell apoptosis in patients with inflammatory bowel diseases via TNF receptor 2 and intestinal CD14⁺ macrophages. Gastroenterology. vol 141. issue 6. 2012-02-06. PMID:21875498. |
antibodies against tumor necrosis factor (tnf) induce t-cell apoptosis in patients with inflammatory bowel diseases via tnf receptor 2 and intestinal cd14⁺ macrophages. |
2012-02-06 |
2023-08-12 |
Not clear |
| Yi Liu, Lei Wang, Takashi Kikuiri, Kentaro Akiyama, Chider Chen, Xingtian Xu, Ruili Yang, Wanjun Chen, Songlin Wang, Songtao Sh. Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α. Nature medicine. vol 17. issue 12. 2012-02-02. PMID:22101767. |
we also found that, through inhibition of nuclear factor κb (nf-κb), tnf-α converts the signaling of the ifn-γ-activated, nonapoptotic form of tnf receptor superfamily member 6 (fas) in bmmscs to a caspase 3- and caspase 8-associated proapoptotic cascade, resulting in the apoptosis of these cells. |
2012-02-02 |
2023-08-12 |
mouse |
| Nives Pustisek, Mirna Situ. UV-radiation, apoptosis and skin. Collegium antropologicum. vol 35 Suppl 2. 2012-01-31. PMID:22220467. |
the extrinsic pathway through death receptors such as fibroblast-associated, tumour necrosis factor receptor and tnf related apoptosis inducing ligand receptor activate caspase cascade. |
2012-01-31 |
2023-08-12 |
Not clear |
| Marie Anne O'Donnell, Eva Perez-Jimenez, Andrew Oberst, Aylwin Ng, Ramin Massoumi, Ramnik Xavier, Douglas R Green, Adrian T Tin. Caspase 8 inhibits programmed necrosis by processing CYLD. Nature cell biology. vol 13. issue 12. 2012-01-26. PMID:22037414. |
caspase 8 initiates apoptosis downstream of tnf death receptors by undergoing autocleavage and processing the executioner caspase 3 (ref. |
2012-01-26 |
2023-08-12 |
Not clear |
| Florian R Grete. TAK1: Another mesh in the NF-κB - JNK controlled network causing hepatocellular carcinoma. Journal of hepatology. vol 55. issue 3. 2012-01-23. PMID:21601601. |
tak1-mediated cancer suppression is exerted through activating nf-kappab in response to tumor necrosis factor (tnf) and through preventing caspase-3-dependent hepatocyte and cholangiocyte apoptosis. |
2012-01-23 |
2023-08-12 |
Not clear |
| Jing Zhao, Yixin Lu, Han-Ming She. Targeting p53 as a therapeutic strategy in sensitizing TRAIL-induced apoptosis in cancer cells. Cancer letters. vol 314. issue 1. 2012-01-18. PMID:22030255. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) has been intensively studied as a cancer therapeutic agent due to its unique ability to induce apoptosis in malignant cells but not in normal cells. |
2012-01-18 |
2023-08-12 |
human |
| Chung S Lee, Yun J Kim, Wonyong Kim, Soon C Myun. Guanylate cyclase activator YC-1 enhances TRAIL-induced apoptosis in human epithelial ovarian carcinoma cells via activation of apoptosis-related proteins. Basic & clinical pharmacology & toxicology. vol 109. issue 4. 2012-01-12. PMID:21554547. |
to assess the ability of 3-(5'-hydroxymethyl-2'-furyl)-1-benzyl indazole (yc-1) to promote apoptosis, we investigated the effect of yc-1 on tumour necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis in the human epithelial ovarian carcinoma cell lines. |
2012-01-12 |
2023-08-12 |
human |
| Miho Nagai, Kouichi Hirayama, Itaru Ebihara, Takashi Higuchi, Masahiro Imaizumi, Hiroshi Maruyama, Yasunori Miyamoto, Tomoko Kakita, Yujiro Ogawa, Shogo Fujita, Homare Shimohata, Masaki Kobayash. Serum TNF-related and weak inducer of apoptosis levels in septic shock patients. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy. vol 15. issue 4. 2012-01-12. PMID:21884467. |
we have previously reported elevated levels of angiopoietin-2 in patients with septic shock, and have investigated tumor necrosis factor (tnf)-related and weak inducer of apoptosis (tweak), which mediates both angiogenesis and inflammation, in those patients. |
2012-01-12 |
2023-08-12 |
Not clear |
| Jennifer S Michaelson, Aldo Amatucci, Rebecca Kelly, Lihe Su, Ellen Garber, Eric S Day, Lisa Berquist, Sandy Cho, You Li, Michael Parr, Laure Wille, Pascal Schneider, Kathleen Wortham, Linda C Burkly, Yen-Ming Hsu, Ingrid B J K Josep. Development of an Fn14 agonistic antibody as an anti-tumor agent. mAbs. vol 3. issue 4. 2012-01-11. PMID:21697654. |
studies described herein show that biib036 binds specifically to fn14 but not other members of the tnf receptor family, induces fn14 signaling, and promotes tumor cell apoptosis in vitro. |
2012-01-11 |
2023-08-12 |
human |
| You-Jin Lee, Jae-Won Seol, Jae-Kyo Jeong, Myung-Hee Moon, Sang-Youel Par. Inhibition of the ubiquitin-proteasome system sensitizes TRAIL-resistant prostate cancer cells by up-regulation of death receptor 5. Molecular medicine reports. vol 4. issue 6. 2012-01-09. PMID:21850375. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a type ii transmembrane cytokine and a potent inducer of apoptosis in cancer cells. |
2012-01-09 |
2023-08-12 |
Not clear |
| Parameswaran Ramakrishnan, David Baltimor. Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor. Molecular cell. vol 43. issue 2. 2012-01-03. PMID:21620750. |
sam68 is required for both nf-κb activation and apoptosis signaling by the tnf receptor. |
2012-01-03 |
2023-08-12 |
Not clear |
| Parameswaran Ramakrishnan, David Baltimor. Sam68 is required for both NF-κB activation and apoptosis signaling by the TNF receptor. Molecular cell. vol 43. issue 2. 2012-01-03. PMID:21620750. |
these findings delineate previously unknown functions for sam68 in the tnf signaling pathway, where it acts as a signaling adaptor both in the membrane-associated complex i and in the cytoplasmic complex ii, regulating both nf-κb activation and apoptosis. |
2012-01-03 |
2023-08-12 |
Not clear |
| S Herman, N Zurgil, S Machlav, A Shinberg, P Langevitz, M Ehrenfeld, M Deutsc. Distinct effects of anti-tumor necrosis factor combined therapy on TH1/TH2 balance in rheumatoid arthritis patients. Clinical and vaccine immunology : CVI. vol 18. issue 7. 2011-12-27. PMID:21593236. |
the therapeutic effect of mtx and tnf blockers may be due to apoptosis induction in lymphocytes infiltrating from the inflammation site and restoring the th1/th2 balance. |
2011-12-27 |
2023-08-12 |
Not clear |
| Sumit K Sood, Sabapathy Balasubramanian, Sue Higham, Malee Fernando, Barney Harriso. Osteoprotegerin (OPG) and related proteins (RANK, RANKL and TRAIL) in thyroid disease. World journal of surgery. vol 35. issue 9. 2011-12-23. PMID:21748518. |
osteoprotegerin (opg), receptor activator of nuclear factor kappab (rank), rank ligand (rankl), and tnf related apoptosis inducing ligand (trail) are the key proteins in the development of bone metastases. |
2011-12-23 |
2023-08-12 |
Not clear |
| Kati Juuti-Uusitalo, Leon J Klunder, Klaas A Sjollema, Katarina Mackovicova, Ryuichi Ohgaki, Dick Hoekstra, Jan Dekker, Sven C D van Ijzendoor. Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture. PloS one. vol 6. issue 8. 2011-12-19. PMID:21853060. |
the cytokines tnf (tnfsf2) and ifnγ are important mediators of inflammatory bowel diseases and contribute to enhanced intestinal epithelial permeability by stimulating apoptosis and/or disrupting tight junctions. |
2011-12-19 |
2023-08-12 |
Not clear |
| Kati Juuti-Uusitalo, Leon J Klunder, Klaas A Sjollema, Katarina Mackovicova, Ryuichi Ohgaki, Dick Hoekstra, Jan Dekker, Sven C D van Ijzendoor. Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture. PloS one. vol 6. issue 8. 2011-12-19. PMID:21853060. |
apoptosis and tight junctions are also important for epithelial tissue morphogenesis, but the effect of tnf and ifnγ on the process of intestinal epithelial morphogenesis is unknown. |
2011-12-19 |
2023-08-12 |
Not clear |