| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhiying Qi, Lirong Yin, Yanying Xu, Fang Wan. Pegylated liposomal‑paclitaxel induces ovarian cancer cell apoptosis via TNF‑induced ERK/AKT signaling pathway. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620264. |
the observations of the present study revealed that pl‑ptx induced ovarian cell apoptosis via the tnf‑dependent pathway, which was significantly inhibited with the employment of antibodies against tnf. |
2018-09-26 |
2023-08-13 |
mouse |
| Shanshan Shen, Chunyang Li, Mingjia Dai, Xuebing Ya. Induction of Huh‑7 cell apoptosis by HCV core proteins via CK1α‑p53‑Bid signaling pathway. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29620268. |
hepatitis c virus (hcv)‑infected liver cells sensitize host cells to tumor necrosis factor (tnf)‑related apoptosis‑inducing ligand (trail)‑induced cell apoptosis; however, the precise mechanisms are unknown. |
2018-09-26 |
2023-08-13 |
human |
| Chunlei Wan, Xiaozhen Liu, Baoling Bai, Haiyan Cao, Huili Li, Qin Zhan. Regulation of the expression of tumor necrosis factor‑related genes by abnormal histone H3K27 acetylation: Implications for neural tube defects. Molecular medicine reports. vol 17. issue 6. 2018-09-26. PMID:29693124. |
among 84 key genes involved in programmed cell death, 13 genes, including tumor necrosis factor (tnf), annexin a5, apoptosis inhibitor 5, bcl2‑associated athanogene 3, baculoviral iap repeat‑containing 3, caspase (casp)12, casp4, casp8, lymphotoxin β receptor, nlr family, apoptosis inhibitory protein 2, tnf receptor superfamily (tnfrsf)1a, tnf superfamily (tnfs)f10 and tnfsf12, were downregulated, whereas nucleolar protein 3 was upregulated in the ra‑induced ntd mice. |
2018-09-26 |
2023-08-13 |
mouse |
| Burcu Kasap, Ümmühani Özel Türkçü, Eren Akbaba, Behiye Sarıyıldız, Mert Küçük, Nilgün Öztürk Turhan, Gökalp Öner, Aykut Özca. The predictive role of sTWEAK levels in pregnant women with first-trimester vaginal bleeding The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. vol 31. issue 13. 2018-09-26. PMID:28462593. |
the predictive role of stweak levels in pregnant women with first-trimester vaginal bleeding to investigate the relationships of tnf-related weak inducer of apoptosis (stweak), a cytokine related to the tnf superfamily, its newly described soluble receptor scd163, and the stweak/scd163 ratio with perinatal outcomes in women with first-trimester vaginal bleeding. |
2018-09-26 |
2023-08-13 |
Not clear |
| Shaowen Zhu, Wanfu Wei, Zhiwei Liu, Yang Yang, Haobo Ji. Tanshinone‑IIA attenuates the deleterious effects of oxidative stress in osteoporosis through the NF‑κB signaling pathway. Molecular medicine reports. vol 17. issue 5. 2018-09-21. PMID:29568934. |
in addition, tan‑iia inhibited the activation of nuclear factor (nf)‑κb and its target genes, tumor necrosis factor (tnf)‑α, inducible nitric oxide synthase and cyclooxygenase 2, and increased the levels of tnf receptor‑associated factor 1 and inhibitor of apoptosis protein‑1/2 in the osteocytes. |
2018-09-21 |
2023-08-13 |
mouse |
| Rout George Kerry, Sushanto Gouda, Bikram Sil, Gitishree Das, Han-Seung Shin, Gajanan Ghodake, Jayanta Kumar Patr. Cure of tuberculosis using nanotechnology: An overview. Journal of microbiology (Seoul, Korea). vol 56. issue 5. 2018-09-10. PMID:29721825. |
the bacterium inhabits the host macrophage and other immune cells where it modulates the lysosome trafficking protein, hinders the formation of phagolysosome, and blocks the tnf receptor-dependent apoptosis of host macrophage/monocytes. |
2018-09-10 |
2023-08-13 |
human |
| Yeoun-Hee Kim, Tae Woo Oh, Eunhee Park, Nam-Hui Yim, Kwang Il Park, Won Kyung Cho, Jin Yeul M. Anti-Inflammatory and Anti-Apoptotic Effects of Acer Palmatum Thumb. Extract, KIOM-2015EW, in a Hyperosmolar-Stress-Induced In Vitro Dry Eye Model. Nutrients. vol 10. issue 3. 2018-09-04. PMID:29495608. |
tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6 production and apoptosis were observed, and the activation of mitogen-activated protein kinases (mapks) including extracellular signal regulated kinase (erk), p38 and c-jun n-terminal kinase (jnk) signaling and nuclear factor (nf)-κb was confirmed. |
2018-09-04 |
2023-08-13 |
human |
| Xianliang Zeng, Sizeng Chen, Yanfeng Lin, Zhao K. Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells. Oncology reports. vol 39. issue 3. 2018-08-31. PMID:29328480. |
we found that the coculture induced myoblast apoptosis and increased tumor necrosis factor (tnf)‑α concentrations in the culture medium. |
2018-08-31 |
2023-08-13 |
Not clear |
| Ning Zhang, Junjun Qiu, Tingting Zheng, Xiaodan Zhang, Keqin Hua, Ying Zhan. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncology reports. vol 39. issue 3. 2018-08-28. PMID:29286125. |
through human apoptosis gene pcr array, we verified that the promotion of eoc cell apoptosis by goserelin was linked to the upregulation of members of the tumor necrosis factor (tnf) and tnf receptor superfamilies, which have been identified as downstream targets of forkhead box o1 (foxo1). |
2018-08-28 |
2023-08-13 |
human |
| Ling-Zhi Ding, Xiao Teng, Zhao-Bo Zhang, Chang-Jun Zheng, Shi-Hong Che. Mangiferin inhibits apoptosis and oxidative stress via BMP2/Smad-1 signaling in dexamethasone-induced MC3T3-E1 cells. International journal of molecular medicine. vol 41. issue 5. 2018-08-27. PMID:29484386. |
after dex and/or mangiferin treatment, cell viability, apoptosis and reactive oxygen species (ros) production was measured by cell counting kit-8 (cck-8) and flow cytometry, respectively, and the concentration of tumor necrosis factor (tnf)-α, interleukin (il)-6 and macrophage colony-stimulating factor (m-csf) was measured by elisa. |
2018-08-27 |
2023-08-13 |
Not clear |
| Wei-An Chang, Meng-Chi Yen, Jen-Yu Hung, Chih-Jen Yang, Shu-Fang Jian, I-Jeng Yeh, Kuan-Ting Liu, Ya-Ling Hsu, Po-Lin Ku. Investigation of the role of tumor necrosis factor-like weak inducer of apoptosis in non-small cell lung cancer. Oncology reports. vol 39. issue 2. 2018-08-23. PMID:29251323. |
tumor necrosis factor (tnf)‑like weak inducer of apoptosis (tweak) is a member of the tnf superfamily and is a ligand of fibroblast growth factor inducible 14 (fn14). |
2018-08-23 |
2023-08-13 |
human |
| Xin Wang, Yu Jin, Yue-Xiu Li, Ya Yan. Secretory leukocyte peptidase inhibitor expression and apoptosis effect in oral leukoplakia and oral squamous cell carcinoma. Oncology reports. vol 39. issue 4. 2018-08-21. PMID:29436667. |
mechanistic studies indicated that slpi, at least in part, regulated cell apoptosis by inhibiting the expression of tnf receptor-associated factor 1 (traf1), which has a close relationship with the nuclear factor-κb (nf-κb) pathway. |
2018-08-21 |
2023-08-13 |
Not clear |
| Lei Shi, Zaizong Wang, Xianjin Liu, Mao Li, Shangfei Zhang, Xiaobin Son. Bax inhibitor-1 is required for resisting the Early Brain Injury induced by subarachnoid hemorrhage through regulating IRE1-JNK pathway. Neurological research. vol 40. issue 3. 2018-08-20. PMID:29334839. |
results we found that bi-1 knockdown increased histological injury and the percentages of tunel-positive neuron in hippocampal, promoted the expressions of endoplasmic reticulum (er) stress proteins inositol-requiring enzyme 1α (ire1α) and tnf receptor-associated factor 2 (traf2), and increased the activation levels of apoptosis signal-regulating kinase 1 (ask1) and c-jun n-terminal kinase (jnk) in the hippocampus of sah rats compared with rats in sah + vehicle group. |
2018-08-20 |
2023-08-13 |
rat |
| J-X Guo, Y-H Zhou, Y-Q Huang, G-J Liu, J-X Pa. Synergistic effects of chlorambucil and TRAIL on apoptosis and proliferation of Raji cells. European review for medical and pharmacological sciences. vol 21. issue 20. 2018-08-16. PMID:29131242. |
tumor necrosis factor (tnf) related apoptosis inducing ligand (trail) can induce the apoptosis of tumor cells, but leaving its effect on malignant lymphoma largely insignificant, as these tumors may develop drug resistance. |
2018-08-16 |
2023-08-13 |
Not clear |
| Olivier Michea. Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation. International journal of molecular sciences. vol 19. issue 3. 2018-08-16. PMID:29498673. |
tumor necrosis-factor related apoptosis-inducing ligand, also known as trail or apo2l (apo-2 ligand), is a cytokine of the tnf superfamily acknowledged for its ability to trigger selective apoptosis in tumor cells while being relatively safe towards normal cells. |
2018-08-16 |
2023-08-13 |
Not clear |
| Adel Naimi, Ali Akbar Movassaghpour, Majid Farshdousti Hagh, Mehdi Talebi, Atefeh Entezari, Farhad Jadidi-Niaragh, Saeed Solal. TNF-related apoptosis-inducing ligand (TRAIL) as the potential therapeutic target in hematological malignancies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 98. 2018-08-13. PMID:29288972. |
tnf-related apoptosis-inducing ligand (trail), a member of tnf superfamily, has significantly attracted the researchers to use it as an effective treatment strategy for cancer since it can preferentially induce apoptosis in a variety of primary tumor cells without affecting the adjacent normal cells. |
2018-08-13 |
2023-08-13 |
Not clear |
| Zhong-Hua Wang, Xin-Yong Sun, Chun-Lei Li, Yan-Ming Sun, Jia Li, Lan-Feng Wang, Zhu-Qin L. miRNA-21 Expression in the Serum of Elderly Patients with Acute Myocardial Infarction. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-08-06. PMID:29197221. |
following tumor necrosis factor (tnf)-α induction, the apoptosis rates of hcm transfected with the mirna-21 mimic short hairpin rna (shrna) were downregulated by 39.1% compared with control hcm cells, and protein expression of c-jun n-terminal kinases (jnk) and p38 were unchanged (p>0.05); protein expression of p-jnk, p-p38 and caspase-3 were downregulated by 37.1%, 35.8%, and 36.0%, respectively. |
2018-08-06 |
2023-08-13 |
human |
| Amit K Mehta, Donald T Gracias, Michael Crof. TNF activity and T cells. Cytokine. vol 101. 2018-07-31. PMID:27531077. |
tnf can promote the activation and proliferation of naïve and effector t cells, but also can induce apoptosis of highly activated effector t cells, further determining the size of the pathogenic or protective conventional t cell pool. |
2018-07-31 |
2023-08-13 |
Not clear |
| Seung-Eun Song, Su-Kyung Shin, Hyun-Woo Cho, Seung-Soon Im, Jae-Hoon Bae, Seon Min Woo, Taeg-Kyu Kwon, Dae-Kyu Son. Tomatidine inhibits tumor necrosis factor-α-induced apoptosis in C Molecular and cellular biochemistry. vol 444. issue 1-2. 2018-07-25. PMID:29196971. |
tomatidine inhibits tumor necrosis factor-α-induced apoptosis in c in this study, we examined the effect of tomatidine on tumor necrosis factor (tnf)-α-induced apoptosis in c |
2018-07-25 |
2023-08-13 |
Not clear |
| Mahboubeh Ebrahimian, Sahar Taghavi, Maryam Ghoreishi, Shahrzad Sedghi, Sara Amel Farzad, Mohammad Ramezani, Maryam Hashem. Evaluation of Efficiency of Modified Polypropylenimine (PPI) with Alkyl Chains as Non-viral Vectors Used in Co-delivery of Doxorubicin and TRAIL Plasmid. AAPS PharmSciTech. vol 19. issue 3. 2018-07-18. PMID:29116619. |
in this study, co-delivery system was achieved via plasmid encoding tnf related apoptosis inducing ligand (ptrail) and doxorubicin (dox) using carrier based on polypropylenimine (ppi) modified with 10-bromodecanoic acid. |
2018-07-18 |
2023-08-13 |
Not clear |