| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W K M Omeka, D S Liyanage, Thanthrige Thiunuwan Priyathilaka, Hyukjae Kwon, Seongdo Lee, Jehee Le. Characterization of four C1q/TNF-related proteins (CTRPs) from red-lip mullet (Liza haematocheila) and their transcriptional modulation in response to bacterial and pathogen-associated molecular pattern stimuli. Fish & shellfish immunology. vol 84. 2019-03-22. PMID:30287348. |
the structural and evolutionary linkage between tumor necrosis factor (tnf) and the globular c1q (gc1q) domain defines the c1q and tnf-related proteins (ctrps), which are involved in diverse functions such as immune defense, inflammation, apoptosis, autoimmunity, and cell differentiation. |
2019-03-22 |
2023-08-13 |
Not clear |
| Gabriel Virella, Kelsey Wilson, Johnathon Elkes, Samar M Hammad, Hussein A Rajab, Yanchun Li, Charlyne Chassereau, Yan Huang, Maria Lopes-Virell. Immune complexes containing malondialdehyde (MDA) LDL induce apoptosis in human macrophages. Clinical immunology (Orlando, Fla.). vol 187. 2019-03-18. PMID:28689783. |
mda-ldl ic induced higher degrees of apoptosis, higher levels of caspase-3 expression, and increased expression and release of mmp-1 and tnf compared to mda-ldl, oxldl, and oxldl ic. |
2019-03-18 |
2023-08-13 |
human |
| Gabriel Virella, Kelsey Wilson, Johnathon Elkes, Samar M Hammad, Hussein A Rajab, Yanchun Li, Charlyne Chassereau, Yan Huang, Maria Lopes-Virell. Immune complexes containing malondialdehyde (MDA) LDL induce apoptosis in human macrophages. Clinical immunology (Orlando, Fla.). vol 187. 2019-03-18. PMID:28689783. |
in conclusion, the interaction of mda-ldl ic with fcγri triggers macrophage apoptosis and increased expression and release of tnf and mmp-1, which can lead to the rupture of unstable plaques. |
2019-03-18 |
2023-08-13 |
human |
| Verena Wieser, Irina Tsibulak, Christine Degasper, Hannah Welponer, Katharina Leitner, Walther Parson, Alain G Zeimet, Christian Marth, Heidelinde Fieg. Tumor necrosis factor receptor modulator spermatogenesis-associated protein 2 is a novel predictor of outcome in ovarian cancer. Cancer science. vol 110. issue 3. 2019-03-08. PMID:30697874. |
recently, spermatogenesis-associated protein 2 (spata2) was identified as a tnf receptor modulator which is required for tnf-induced inflammation and apoptosis. |
2019-03-08 |
2023-08-13 |
Not clear |
| Stephane J de M Escobar, Genevieve M Fong, Sheila M B Winnischofer, Martin Simone, Lenka Munoz, Joanne M Dennis, Maria Eliane M Rocha, Paul K Wittin. Anti-proliferative and cytotoxic activities of the flavonoid isoliquiritigenin in the human neuroblastoma cell line SH-SY5Y. Chemico-biological interactions. vol 299. 2019-02-04. PMID:30502331. |
isl-mediated cell toxicity did not involve intracellular caspase 3/7 activation, externalization of phosphatidylserine on the cell membrane or stimulation of tnf and il-1β release, all indicating that the flavonoid did not induce apoptosis. |
2019-02-04 |
2023-08-13 |
human |
| Brian Hassett, Ena Singh, Ehab Mahgoub, Julie O'Brien, Steven M Vicik, Brian Fitzpatric. Manufacturing history of etanercept (Enbrel mAbs. vol 10. issue 1. 2019-01-07. PMID:29020515. |
based on the key quality attributes of product purity (assessed by hydrophobic interaction chromatography hplc), binding activity (to tnf by elisa), potency (inhibition of tnf-induced apoptosis by cell-based bioassay) and quality (n-linked oligosaccharide map), we show that the integrity of etn ds has remained consistent over time. |
2019-01-07 |
2023-08-13 |
human |
| Rui-Da Xu, Fan Feng, Xiao-Sheng Yu, Zu-De Liu, Li-Feng La. miR-149-5p inhibits cell growth by regulating TWEAK/Fn14/PI3K/AKT pathway and predicts favorable survival in human osteosarcoma. International journal of immunopathology and pharmacology. vol 32. 2018-12-18. PMID:30014744. |
furthermore, we identified tnfrsf12a (tnf receptor superfamily member 12a), also called fibroblast growth factor-inducible 14 (fn14) as a direct target of mir-149, and tnfrsf12a and its ligand tnfsf12 (tnf superfamily member 12), also called tumor necrosis factor-related weak inducer of apoptosis (tweak), were both negatively correlated with mir-149 expression in sarcoma samples. |
2018-12-18 |
2023-08-13 |
human |
| Xu Wu, Shengpeng Wang, Mingxing Li, Anqi Wang, Yangyang Zhou, Peng Li, Yitao Wan. Nanocarriers for TRAIL delivery: driving TRAIL back on track for cancer therapy. Nanoscale. vol 9. issue 37. 2018-12-11. PMID:28914952. |
since its initial identification, tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) has been shown to be capable of selectively inducing apoptosis in cancer cells. |
2018-12-11 |
2023-08-13 |
Not clear |
| Dawei Xu, Wei Zhao, Chengniu Wang, Hao Zhu, Mingqing He, Xinhui Zhu, Wei Liu, Fei Wang, Jianbo Fan, Chu Chen, Daoran Cui, Zhiming Cu. Up-regulation of TNF Receptor-associated Factor 7 after spinal cord injury in rats may have implication for neuronal apoptosis. Neuropeptides. vol 71. 2018-12-11. PMID:30100091. |
up-regulation of tnf receptor-associated factor 7 after spinal cord injury in rats may have implication for neuronal apoptosis. |
2018-12-11 |
2023-08-13 |
rat |
| Xianping Zhu, Lin Wang, Xiao Teng, Qi Chen, Chenshuai Pa. N-Methyl Pyrrolidone (NMP) Alleviates Lipopolysaccharide (LPS)-Induced Inflammatory Injury in Articular Chondrocytes. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-11. PMID:30218608. |
cell viability was measured using cck-8 assay; cell apoptosis was detected using fcm; related protein and mrna expressions were determined using western blot assay and qrt-pcr assay; and inflammatory factors (tumor necrosis factor (tnf)-α, interleukin (il)-1β, il-6, and il-8) productions were measured by performing elisa assay. |
2018-12-11 |
2023-08-13 |
Not clear |
| Andrew T Holdbrooks, Colleen M Britain, Susan L Belli. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor. The Journal of biological chemistry. vol 293. issue 5. 2018-11-27. PMID:29233887. |
however, upon extended tnf treatment (6-24 h), cells with high st6gal-i levels exhibited resistance to tnf-induced apoptosis, as indicated by morphological evidence of cell death and decreased activation of caspases 8 and 3. |
2018-11-27 |
2023-08-13 |
Not clear |
| Kamal Shaik Fakiruddin, Nadiah Ghazalli, Moon Nian Lim, Zubaidah Zakaria, Syahril Abdulla. Mesenchymal Stem Cell Expressing TRAIL as Targeted Therapy against Sensitised Tumour. International journal of molecular sciences. vol 19. issue 8. 2018-11-21. PMID:30060445. |
engineered mscs expressing tumour necrosis factor (tnf)-related apoptosis inducing ligand (msc-trail) could serve as a platform for an efficient and targeted form of therapy. |
2018-11-21 |
2023-08-13 |
Not clear |
| Shengpeng Wang, Yingqi Xu, Chenyang Li, Hongxun Tao, Anqi Wang, Chenyu Sun, Zhangfeng Zhong, Xu Wu, Peng Li, Yitao Wan. Gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 119. 2018-11-19. PMID:29458160. |
due to the ability of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) to induce cancer cell apoptosis selectively, trail has attracted significant interest in the treatment of cancer. |
2018-11-19 |
2023-08-13 |
Not clear |
| Alicia M Nevárez-Garza, Uziel Castillo-Velázquez, Adolfo Soto-Domínguez, R Montes-de-Oca-Luna, Diana E Zamora-Ávila, Alfredo Wong-González, Luis E Rodríguez-Tova. Quantitative analysis of TNF-α, IL-4, and IL-10 expression, nitric oxide response, and apoptosis in Encephalitozoon cuniculi-infected rabbits. Developmental and comparative immunology. vol 81. 2018-11-08. PMID:29229442. |
the expression of tumor necrosis factor (tnf) -α, interleukin (il) -4 and il-10, as well as apoptosis and nitric oxide (no) levels were measured in the brain and kidneys of immunocompetent and immunosuppressed new zealand white rabbits infected with encephalitozoon cuniculi. |
2018-11-08 |
2023-08-13 |
Not clear |
| Meng Li, Xiang Yang, Shouchuan Wan. PTEN enhances nasal epithelial cell resistance to TNFα‑induced inflammatory injury by limiting mitophagy via repression of the TLR4‑JNK‑Bnip3 pathway. Molecular medicine reports. vol 18. issue 3. 2018-11-08. PMID:30015897. |
in the present study, tumor necrosis factor (tnf)α was used to induce an inflammatory injury and explore the underlying pathogenesis for nasal epithelial cell apoptosis in vitro, with a focus on mitochondrial homeostasis. |
2018-11-08 |
2023-08-13 |
Not clear |
| Sajad Hassanzadeh, Seyed Behnamedin Jameie, Maryam Soleimani, Mona Farhadi, Mahdieh Kerdari, Navid Danae. Coenzyme Q10 Influences on the Levels of TNF-α and IL-10 and the Ratio of Bax/Bcl2 in a Menopausal Rat Model Following Lumbar Spinal Cord Injury. Journal of molecular neuroscience : MN. vol 65. issue 2. 2018-11-05. PMID:29948851. |
we hypothesized that in the absence of female gonadal steroids, which provide protection following an sci, coq10 could modulate the expression of cytokines, such as tumor necrosis factor (tnf)-α and interleukin (il)-10, besides aquaporin-4 (aqp4) water channels in the cns, which participate in neuroinflammation, as well as the bax and bcl2 proteins that are involved in apoptosis at the site of injury. |
2018-11-05 |
2023-08-13 |
rat |
| Yuguang Wang, Vikki M Abrahams, Guoyang Luo, Nicholas G Norwitz, Victoria V Snegovskikh, Shu-Wing Ng, Errol R Norwit. Progesterone Inhibits Apoptosis in Fetal Membranes by Altering Expression of Both Pro- and Antiapoptotic Proteins. Reproductive sciences (Thousand Oaks, Calif.). vol 25. issue 8. 2018-11-02. PMID:29463188. |
we have previously shown that progesterone inhibits basal and tumor necrosis factor (tnf) α-induced apoptosis in an explant model of human fetal membranes. |
2018-11-02 |
2023-08-13 |
human |
| Zidan Jin, Jie Yao, Nianlin Xie, Libo Cai, Shuai Qi, Zhan Zhang, Bai L. Melittin Constrains the Expression of Identified Key Genes Associated with Bladder Cancer. Journal of immunology research. vol 2018. 2018-10-11. PMID:29854840. |
based on the analysis of articles retrieved in the pubmed database, we found that melittin could induce apoptosis and constrain the progression of tumor cells as a result of regulating critical cancer-related signaling pathways, such as pi3k-akt and tnf signaling pathways. |
2018-10-11 |
2023-08-13 |
Not clear |
| Muzi Zhang, Ming Li, Rixin Wang, Yunxia Qia. Effects of acute ammonia toxicity on oxidative stress, immune response and apoptosis of juvenile yellow catfish Pelteobagrus fulvidraco and the mitigation of exogenous taurine. Fish & shellfish immunology. vol 79. 2018-10-02. PMID:29802884. |
in addition, ammonia poisoning could induce up-regulation of antioxidant enzymes (cu/zn-sod, cat, gpx and gr), inflammatory cytokines (tnf, il-1 and il-8) and apoptosis (p53, bax, caspase 3 and caspase 9) genes transcription, suggesting that cell apoptotic and inflammation may relate to oxidative stress. |
2018-10-02 |
2023-08-13 |
cat |
| Hao Lin, Yifan Wang, Haoqiang Lai, Xiaoling Li, Tianfeng Che. Iron(II)-Polypyridyl Complexes Inhibit the Growth of Glioblastoma Tumor and Enhance TRAIL-Induced Cell Apoptosis. Chemistry, an Asian journal. vol 13. issue 18. 2018-10-01. PMID:29963768. |
a promising cancer-targeting agent for the induction of apoptosis in tumor necrosis factor (tnf) proteins, the tnf-related apoptosis-inducing ligand (trail) ligand, has found limited applications in the treatment of cancer cells, owing to its resistance by cancer cell lines. |
2018-10-01 |
2023-08-13 |
mouse |