| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rout George Kerry, Sushanto Gouda, Bikram Sil, Gitishree Das, Han-Seung Shin, Gajanan Ghodake, Jayanta Kumar Patr. Cure of tuberculosis using nanotechnology: An overview. Journal of microbiology (Seoul, Korea). vol 56. issue 5. 2018-09-10. PMID:29721825. |
the bacterium inhabits the host macrophage and other immune cells where it modulates the lysosome trafficking protein, hinders the formation of phagolysosome, and blocks the tnf receptor-dependent apoptosis of host macrophage/monocytes. |
2018-09-10 |
2023-08-13 |
human |
| Yeoun-Hee Kim, Tae Woo Oh, Eunhee Park, Nam-Hui Yim, Kwang Il Park, Won Kyung Cho, Jin Yeul M. Anti-Inflammatory and Anti-Apoptotic Effects of Acer Palmatum Thumb. Extract, KIOM-2015EW, in a Hyperosmolar-Stress-Induced In Vitro Dry Eye Model. Nutrients. vol 10. issue 3. 2018-09-04. PMID:29495608. |
tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6 production and apoptosis were observed, and the activation of mitogen-activated protein kinases (mapks) including extracellular signal regulated kinase (erk), p38 and c-jun n-terminal kinase (jnk) signaling and nuclear factor (nf)-κb was confirmed. |
2018-09-04 |
2023-08-13 |
human |
| Xianliang Zeng, Sizeng Chen, Yanfeng Lin, Zhao K. Acylated and unacylated ghrelin inhibit apoptosis in myoblasts cocultured with colon carcinoma cells. Oncology reports. vol 39. issue 3. 2018-08-31. PMID:29328480. |
we found that the coculture induced myoblast apoptosis and increased tumor necrosis factor (tnf)‑α concentrations in the culture medium. |
2018-08-31 |
2023-08-13 |
Not clear |
| Ning Zhang, Junjun Qiu, Tingting Zheng, Xiaodan Zhang, Keqin Hua, Ying Zhan. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncology reports. vol 39. issue 3. 2018-08-28. PMID:29286125. |
through human apoptosis gene pcr array, we verified that the promotion of eoc cell apoptosis by goserelin was linked to the upregulation of members of the tumor necrosis factor (tnf) and tnf receptor superfamilies, which have been identified as downstream targets of forkhead box o1 (foxo1). |
2018-08-28 |
2023-08-13 |
human |
| Ling-Zhi Ding, Xiao Teng, Zhao-Bo Zhang, Chang-Jun Zheng, Shi-Hong Che. Mangiferin inhibits apoptosis and oxidative stress via BMP2/Smad-1 signaling in dexamethasone-induced MC3T3-E1 cells. International journal of molecular medicine. vol 41. issue 5. 2018-08-27. PMID:29484386. |
after dex and/or mangiferin treatment, cell viability, apoptosis and reactive oxygen species (ros) production was measured by cell counting kit-8 (cck-8) and flow cytometry, respectively, and the concentration of tumor necrosis factor (tnf)-α, interleukin (il)-6 and macrophage colony-stimulating factor (m-csf) was measured by elisa. |
2018-08-27 |
2023-08-13 |
Not clear |
| Wei-An Chang, Meng-Chi Yen, Jen-Yu Hung, Chih-Jen Yang, Shu-Fang Jian, I-Jeng Yeh, Kuan-Ting Liu, Ya-Ling Hsu, Po-Lin Ku. Investigation of the role of tumor necrosis factor-like weak inducer of apoptosis in non-small cell lung cancer. Oncology reports. vol 39. issue 2. 2018-08-23. PMID:29251323. |
tumor necrosis factor (tnf)‑like weak inducer of apoptosis (tweak) is a member of the tnf superfamily and is a ligand of fibroblast growth factor inducible 14 (fn14). |
2018-08-23 |
2023-08-13 |
human |
| Xin Wang, Yu Jin, Yue-Xiu Li, Ya Yan. Secretory leukocyte peptidase inhibitor expression and apoptosis effect in oral leukoplakia and oral squamous cell carcinoma. Oncology reports. vol 39. issue 4. 2018-08-21. PMID:29436667. |
mechanistic studies indicated that slpi, at least in part, regulated cell apoptosis by inhibiting the expression of tnf receptor-associated factor 1 (traf1), which has a close relationship with the nuclear factor-κb (nf-κb) pathway. |
2018-08-21 |
2023-08-13 |
Not clear |
| Lei Shi, Zaizong Wang, Xianjin Liu, Mao Li, Shangfei Zhang, Xiaobin Son. Bax inhibitor-1 is required for resisting the Early Brain Injury induced by subarachnoid hemorrhage through regulating IRE1-JNK pathway. Neurological research. vol 40. issue 3. 2018-08-20. PMID:29334839. |
results we found that bi-1 knockdown increased histological injury and the percentages of tunel-positive neuron in hippocampal, promoted the expressions of endoplasmic reticulum (er) stress proteins inositol-requiring enzyme 1α (ire1α) and tnf receptor-associated factor 2 (traf2), and increased the activation levels of apoptosis signal-regulating kinase 1 (ask1) and c-jun n-terminal kinase (jnk) in the hippocampus of sah rats compared with rats in sah + vehicle group. |
2018-08-20 |
2023-08-13 |
rat |
| J-X Guo, Y-H Zhou, Y-Q Huang, G-J Liu, J-X Pa. Synergistic effects of chlorambucil and TRAIL on apoptosis and proliferation of Raji cells. European review for medical and pharmacological sciences. vol 21. issue 20. 2018-08-16. PMID:29131242. |
tumor necrosis factor (tnf) related apoptosis inducing ligand (trail) can induce the apoptosis of tumor cells, but leaving its effect on malignant lymphoma largely insignificant, as these tumors may develop drug resistance. |
2018-08-16 |
2023-08-13 |
Not clear |
| Olivier Michea. Regulation of TNF-Related Apoptosis-Inducing Ligand Signaling by Glycosylation. International journal of molecular sciences. vol 19. issue 3. 2018-08-16. PMID:29498673. |
tumor necrosis-factor related apoptosis-inducing ligand, also known as trail or apo2l (apo-2 ligand), is a cytokine of the tnf superfamily acknowledged for its ability to trigger selective apoptosis in tumor cells while being relatively safe towards normal cells. |
2018-08-16 |
2023-08-13 |
Not clear |
| Adel Naimi, Ali Akbar Movassaghpour, Majid Farshdousti Hagh, Mehdi Talebi, Atefeh Entezari, Farhad Jadidi-Niaragh, Saeed Solal. TNF-related apoptosis-inducing ligand (TRAIL) as the potential therapeutic target in hematological malignancies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 98. 2018-08-13. PMID:29288972. |
tnf-related apoptosis-inducing ligand (trail), a member of tnf superfamily, has significantly attracted the researchers to use it as an effective treatment strategy for cancer since it can preferentially induce apoptosis in a variety of primary tumor cells without affecting the adjacent normal cells. |
2018-08-13 |
2023-08-13 |
Not clear |
| Zhong-Hua Wang, Xin-Yong Sun, Chun-Lei Li, Yan-Ming Sun, Jia Li, Lan-Feng Wang, Zhu-Qin L. miRNA-21 Expression in the Serum of Elderly Patients with Acute Myocardial Infarction. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-08-06. PMID:29197221. |
following tumor necrosis factor (tnf)-α induction, the apoptosis rates of hcm transfected with the mirna-21 mimic short hairpin rna (shrna) were downregulated by 39.1% compared with control hcm cells, and protein expression of c-jun n-terminal kinases (jnk) and p38 were unchanged (p>0.05); protein expression of p-jnk, p-p38 and caspase-3 were downregulated by 37.1%, 35.8%, and 36.0%, respectively. |
2018-08-06 |
2023-08-13 |
human |
| Amit K Mehta, Donald T Gracias, Michael Crof. TNF activity and T cells. Cytokine. vol 101. 2018-07-31. PMID:27531077. |
tnf can promote the activation and proliferation of naïve and effector t cells, but also can induce apoptosis of highly activated effector t cells, further determining the size of the pathogenic or protective conventional t cell pool. |
2018-07-31 |
2023-08-13 |
Not clear |
| Seung-Eun Song, Su-Kyung Shin, Hyun-Woo Cho, Seung-Soon Im, Jae-Hoon Bae, Seon Min Woo, Taeg-Kyu Kwon, Dae-Kyu Son. Tomatidine inhibits tumor necrosis factor-α-induced apoptosis in C Molecular and cellular biochemistry. vol 444. issue 1-2. 2018-07-25. PMID:29196971. |
tomatidine inhibits tumor necrosis factor-α-induced apoptosis in c in this study, we examined the effect of tomatidine on tumor necrosis factor (tnf)-α-induced apoptosis in c |
2018-07-25 |
2023-08-13 |
Not clear |
| Mahboubeh Ebrahimian, Sahar Taghavi, Maryam Ghoreishi, Shahrzad Sedghi, Sara Amel Farzad, Mohammad Ramezani, Maryam Hashem. Evaluation of Efficiency of Modified Polypropylenimine (PPI) with Alkyl Chains as Non-viral Vectors Used in Co-delivery of Doxorubicin and TRAIL Plasmid. AAPS PharmSciTech. vol 19. issue 3. 2018-07-18. PMID:29116619. |
in this study, co-delivery system was achieved via plasmid encoding tnf related apoptosis inducing ligand (ptrail) and doxorubicin (dox) using carrier based on polypropylenimine (ppi) modified with 10-bromodecanoic acid. |
2018-07-18 |
2023-08-13 |
Not clear |
| I V Kurbatova, L V Topchieva, O P Dudanov. Gene TNF Polymorphism -308G>A (rs1800629) and Its Relationship with the Efficiency of Ursodeoxycholic Acid Therapy in Patients with Nonalcoholic Stetohepatitis. Bulletin of experimental biology and medicine. vol 164. issue 2. 2018-07-16. PMID:29181663. |
patients with nonalcoholic steatohepatitis, differing by the tnf gene -308g>a marker genotype, differ by the time course of the markers of hepatocellular damage (alt, ast), activity of hepatocyte apoptosis (tissue polypeptide-specific antigen), and activation of specific humoral immunity (γ-globulin) in response to therapy with ursodeoxycholic acid in a dose of 10-15 mg/kg over 4-6 weeks. |
2018-07-16 |
2023-08-13 |
human |
| Nicola A Pascarelli, Antonella Fioravanti, Elena Moretti, Giacomo M Guidelli, Lucia Mazzi, Giulia Collode. The effects in vitro of TNF-α and its antagonist 'etanercept' on ejaculated human sperm. Reproduction, fertility, and development. vol 29. issue 6. 2018-07-13. PMID:27185240. |
tumour necrosis factor (tnf)-α is primarily involved in the regulation of cell proliferation and apoptosis; in addition it possesses pro-inflammatory properties. |
2018-07-13 |
2023-08-13 |
human |
| Christopher S Potter, Kathleen A Silva, Victoria E Kennedy, Timothy M Stearns, Harm HogenEsch, John P Sundber. Loss of FAS/FASL signalling does not reduce apoptosis in Sharpin null mice. Experimental dermatology. vol 26. issue 9. 2018-07-13. PMID:28094869. |
affected mice have increased apoptosis in the keratinocytes of the skin, oesophagus and forestomach driven by extrinsic tnf receptor-mediated apoptotic signalling pathways. |
2018-07-13 |
2023-08-13 |
mouse |
| Y Wang, Y-R Zhao, A-Y Zhang, J Ma, Z-Z Wang, X Zhan. Targeting of miR-20a against CFLAR to potentiate TRAIL-induced apoptotic sensitivity in HepG2 cells. European review for medical and pharmacological sciences. vol 21. issue 9. 2018-07-02. PMID:28537677. |
elevated expression of caspase-8 (casp8) and fas-associating protein with a novel death domain (fadd)-like apoptosis regulator (cflar) increases sensitivity against tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced cell apoptosis, but with an unclear mechanism. |
2018-07-02 |
2023-08-13 |
Not clear |
| Fufa Qu, Zhiming Xiang, Yingli Zhou, Yanping Qi. A molluscan TNF receptor-associated factor 2 (TRAF2) was involved in host defense against immune challenges. Fish & shellfish immunology. vol 71. 2018-06-25. PMID:28986217. |
tumor necrosis factor (tnf) receptor-associated factor 2 (traf2) is a member of the traf superfamily that acted as a key signal transduction protein and has been implicated in inflammatory and apoptosis processes in mammals. |
2018-06-25 |
2023-08-13 |
Not clear |