| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthieu Le Gallo, Amanda Poissonnier, Patrick Blanco, Patrick Legembr. CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases. Frontiers in immunology. vol 8. 2019-11-20. PMID:29021794. |
the receptor cd95 (also named fas or apoptosis antigen 1) belongs to the tumor necrosis factor (tnf) receptor superfamily. |
2019-11-20 |
2023-08-13 |
human |
| Bing Xu, Jian Li, Xiaoxin Liu, Chang Li, Xiaotian Chan. TXNDC5 is a cervical tumor susceptibility gene that stimulates cell migration, vasculogenic mimicry and angiogenesis by down-regulating SERPINF1 and TRAF1 expression. Oncotarget. vol 8. issue 53. 2019-11-20. PMID:29207620. |
inhibiting txndc5 expression simultaneously led to the increased expression of serpinf1 (serpin peptidase inhibitor, clade f) and traf1 (tnf receptor-associated factor 1), which have been reported to inhibit angiogenesis and metastasis as well as induce apoptosis. |
2019-11-20 |
2023-08-13 |
human |
| Yen-Sung Huang, Shin-Huei Fu, Kuo-Cheng Lu, Jin-Shuen Chen, Hsin-Yi Hsieh, Huey-Kang Sytwu, Chia-Chao W. Inhibition of tumor necrosis factor signaling attenuates renal immune cell infiltration in experimental membranous nephropathy. Oncotarget. vol 8. issue 67. 2019-11-20. PMID:29340080. |
immune cell subsets, serum immunoglobulin levels, production of reactive oxygen species, and cell apoptosis in the kidney were not altered by tnf inhibition. |
2019-11-20 |
2023-08-13 |
mouse |
| Nickolay Neznanov, Andrei Gudko. Pretreatment of the Cells With Brefeldin A and Cycloheximide Differently Regulates Fas and TNF Stimulated Apoptosis. TheScientificWorldJournal. vol 1. 2019-11-20. PMID:30147489. |
pretreatment of the cells with brefeldin a and cycloheximide differently regulates fas and tnf stimulated apoptosis. |
2019-11-20 |
2023-08-13 |
Not clear |
| A Gonelli, D Milani, E Rimondi, R Voltan, V Grill, C Celeghin. Activation of PKC-ε counteracts maturation and apoptosis of HL-60 myeloid leukemic cells in response to TNF family members. European journal of histochemistry : EJH. vol 53. issue 3. 2019-11-20. PMID:30256868. |
activation of pkc-ε counteracts maturation and apoptosis of hl-60 myeloid leukemic cells in response to tnf family members. |
2019-11-20 |
2023-08-13 |
Not clear |
| Bin Yang, Xiangru Liu, Yongqian Liang, Yue L. Chemical inhibition of HSP90 inhibits TNF-α mediated proliferation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes. Journal of cellular biochemistry. 2019-11-20. PMID:30304567. |
in this study, we explored the effects of hsp90 inhibitor, ga, on tumor necrosis factor (tnf)-α-induced proliferation and apoptosis of rafls, and the underlying mechanism. |
2019-11-20 |
2023-08-13 |
human |
| Kataoka, Tsuru. Physician Education: Apoptosis. The oncologist. vol 1. issue 6. 2019-11-20. PMID:10388021. |
cell injuries that induce apoptosis include those that cause dna damage such as radiation and anticancer drugs, those that are mediated by the tnf receptor and fas receptor (the so-called "death signal receptors"), and the deprivation of cytokines that supply survival signals such as il-3 and erythropoietin. |
2019-11-20 |
2023-08-12 |
mouse |
| H. S. Ryu, K. H. Chang, S. J. Chang, M. S. Kim, H. J. Joo, K. S. O. Expression of TRAIL (TNF-related apoptosis-inducing ligand) receptors in cervical cancer. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 10. issue 5. 2019-11-20. PMID:11240708. |
some of the well known regulators of apoptosis are cytokines of the tumor necrosis factor (tnf) ligand family, such as fas ligand (fas l) and tnf, which induce apoptosis by activation of their corresponding receptors, fas and tnfr-1. |
2019-11-20 |
2023-08-12 |
human |
| H. S. Ryu, K. H. Chang, S. J. Chang, M. S. Kim, H. J. Joo, K. S. O. Expression of TRAIL (TNF-related apoptosis-inducing ligand) receptors in cervical cancer. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society. vol 10. issue 5. 2019-11-20. PMID:11240708. |
recently, a new member of the tnf family known as trail (tnf-related apoptosis-inducing ligand) was identified and shown to induce p53-independent apoptosis in a variety of tumor cell lines but not in normal cells. |
2019-11-20 |
2023-08-12 |
human |
| A Acharya, S M Sing. Effect of TNF-alpha on the induction of apoptosis in murine macrophages: role of interleukin-1 beta converting enzyme. International journal of immunopathology and pharmacology. vol 14. issue 1. 2019-11-20. PMID:12622883. |
macrophages treated with tnf showed a time dependent decrease in cell viability with a simultaneous increase in the percent of cells showing apoptotic morphology and an increase in percent dna fragmentation, a quantitative measure of apoptosis. |
2019-11-20 |
2023-08-12 |
Not clear |
| A Acharya, S M Sing. Effect of TNF-alpha on the induction of apoptosis in murine macrophages: role of interleukin-1 beta converting enzyme. International journal of immunopathology and pharmacology. vol 14. issue 1. 2019-11-20. PMID:12622883. |
however, incubation of macrophage in medium containing tnf and yvad-cmk had inhibitory effect on the tnf-induced apoptosis of macrophage. |
2019-11-20 |
2023-08-12 |
Not clear |
| Yale Liu, Meifeng Xu, Xiaoyun Min, Kunyi Wu, Ting Zhang, Ke Li, Shengxiang Xiao, Yumin Xi. TWEAK/Fn14 Activation Participates in Ro52-Mediated Photosensitization in Cutaneous Lupus Erythematosus. Frontiers in immunology. vol 8. 2019-11-20. PMID:28620393. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) binds to its sole receptor fibroblast growth factor-inducible 14 (fn14), participating in various inflammatory responses. |
2019-11-20 |
2023-08-13 |
Not clear |
| Yu-Fon Chen, Guan-Yu Chen, Chien-Hsiang Chang, Yu-Chu Su, Yi-Cheng Chen, Yi-Sheng Jiang, Jeng-Shiung Ja. TRAIL encapsulated to polypeptide-crosslinked nanogel exhibits increased anti-inflammatory activities in Klebsiella pneumoniae-induced sepsis treatment. Materials science & engineering. C, Materials for biological applications. vol 102. 2019-11-19. PMID:31147057. |
one of the therapeutic approaches widely utilized in inducing apoptosis in inflammatory cells is the use of tumor necrosis factor (tnf)-related apoptosis-inducing ligands (trail), which trigger an extrinsic apoptotic pathway via death receptors. |
2019-11-19 |
2023-08-13 |
mouse |
| Mohamed A Anany, Jennifer Kreckel, Simone Füllsack, Alevtina Rosenthal, Christoph Otto, Daniela Siegmund, Harald Wajan. Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis. Cell death & disease. vol 9. issue 11. 2019-11-13. PMID:30349023. |
ripk1 turned out to be essential for poly(i:c)/tweak-induced caspase-8-mediated apoptosis but was dispensable for this response in tnf and trail signaling. |
2019-11-13 |
2023-08-13 |
Not clear |
| Sylwia Gradzka, Oliver S Thomas, Oliver Kretz, Aladin Haimovici, Lazaros Vasilikos, Wendy Wei-Lynn Wong, Georg Häcker, Ian E Gentl. Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes. Cell death & disease. vol 9. issue 5. 2019-11-08. PMID:29743550. |
inhibitor of apoptosis proteins act as e3 ubiquitin ligases to regulate nf-κb signalling from multiple pattern recognition receptors including nod2, as well as tnf receptor superfamily members. |
2019-11-08 |
2023-08-13 |
Not clear |
| Seisuke Sato, Hitomi Imachi, Jingya Lyu, Yumi Miyai, Kensaku Fukunaga, Tao Dong, Tomohiro Ibata, Toshihiro Kobayashi, Takuo Yoshimoto, Fumi Kikuchi, Kazuko Yonezaki, Nao Yamaji, Hisakazu Iwama, Koji Mura. Effect of TNF-α on the expression of ABCA1 in pancreatic β-cells. Journal of molecular endocrinology. vol 61. issue 4. 2019-10-25. PMID:30131353. |
tumor necrosis factor (tnf)-α is a pleiotropic cytokine that elicits a wide spectrum of physiological events, including cell proliferation, differentiation, and apoptosis, and is also known to decrease glucose-dependent insulin secretion in pancreatic islets. |
2019-10-25 |
2023-08-13 |
rat |
| Yasuo Takashima, Atsushi Kawaguchi, Yasuo Iwadate, Hiroaki Hondoh, Junya Fukai, Koji Kajiwara, Azusa Hayano, Ryuya Yamanak. MicroRNA signature constituted of miR-30d, miR-93, and miR-181b is a promising prognostic marker in primary central nervous system lymphoma. PloS one. vol 14. issue 1. 2019-10-18. PMID:30615673. |
the 16 mirnas were enriched by gene ontology terms including angiogenesis, cell migration and proliferation, and apoptosis, in addition to signaling pathways including tgf-β/smad, notch, tnf, and mapkinase. |
2019-10-18 |
2023-08-13 |
Not clear |
| Nerea Mosquera, Angela Rodriguez-Trillo, Antonio Mera-Varela, Antonio Gonzalez, Carmen Cond. Uncovering Cellular retinoic acid-binding protein 2 as a potential target for rheumatoid arthritis synovial hyperplasia. Scientific reports. vol 8. issue 1. 2019-10-09. PMID:29880835. |
in addition, the potentiation of fls apoptosis by crabp2 silencing persisted in the presence of pro-inflammatory mediators, tnf e il1β. |
2019-10-09 |
2023-08-13 |
Not clear |
| I-Tsu Chyuan, Hwei-Fang Tsai, Hsiu-Jung Liao, Chien-Sheng Wu, Ping-Ning Hs. An apoptosis-independent role of TRAIL in suppressing joint inflammation and inhibiting T-cell activation in inflammatory arthritis. Cellular & molecular immunology. vol 15. issue 9. 2019-10-03. PMID:28392572. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) has been implicated in the regulation of inflammation in rheumatoid arthritis (ra), primarily due to its ability to promote apoptosis in synoviocytes and infiltrating lymphocytes. |
2019-10-03 |
2023-08-13 |
mouse |
| Ali Hassanzadeh, Majid Farshdousti Hagh, Mohammad Reza Alivand, Ali Akbar Movassaghpour Akbari, Karim Shams Asenjan, Raedeh Saraei, Saeed Solal. Down-regulation of intracellular anti-apoptotic proteins, particularly c-FLIP by therapeutic agents; the novel view to overcome resistance to TRAIL. Journal of cellular physiology. vol 233. issue 10. 2019-09-30. PMID:29741767. |
tumor necrosis factor-related apoptosis-inducing ligand (trail or apo2l) is a member of the tumor necrosis factor (tnf) superfamily that induces apoptosis in different types of cancer cells via activation of caspase cascade. |
2019-09-30 |
2023-08-13 |
Not clear |