| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tian He, Rendong Qu, Caimeng Qin, Zheyi Wang, Yue Zhang, Xiangming Shao, Tao L. Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injury. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 28. issue 9. 2020-09-28. PMID:32837217. |
tcm herbs regulate core pathways, such as age-rage, pi3k-akt, tnf and apoptosis pathway, etc. |
2020-09-28 |
2023-08-13 |
Not clear |
| Chao Cheng, Xiao-Bo Liu, Shao-Jie Bi, Qing-Hua Lu, Juan Zhan. Inhibition of Rho-kinase is involved in the therapeutic effects of atorvastatin in heart ischemia/reperfusion. Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32855683. |
the i/r group was found to have increased myocardial infarct size, cardiomyocyte apoptosis, levels of plasma interleukin (il)-6 and tumor necrosis factor (tnf)-α, superoxide dismutase (sod) activity, malondialdehyde (mda) levels and rho-kinase activity compared with the other treatment groups (p<0.05). |
2020-09-28 |
2023-08-13 |
rat |
| Linnan Zhu, Penghui Yang, Yingze Zhao, Zhenkun Zhuang, Zhifeng Wang, Rui Song, Jie Zhang, Chuanyu Liu, Qianqian Gao, Qumiao Xu, Xiaoyu Wei, Hai-Xi Sun, Beiwei Ye, Yanan Wu, Ning Zhang, Guanglin Lei, Lingxiang Yu, Jin Yan, Guanghao Diao, Fanping Meng, Changqing Bai, Panyong Mao, Yeya Yu, Mingyue Wang, Yue Yuan, Qiuting Deng, Ziyi Li, Yunting Huang, Guohai Hu, Yang Liu, Xiaoqian Wang, Ziqian Xu, Peipei Liu, Yuhai Bi, Yi Shi, Shaogeng Zhang, Zhihai Chen, Jian Wang, Xun Xu, Guizhen Wu, Fu-Sheng Wang, George F Gao, Longqi Liu, William J Li. Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients. Immunity. vol 53. issue 3. 2020-09-25. PMID:32783921. |
we observed increase of plasma cells in both covid-19 and iav patients and xiap associated factor 1 (xaf1)-, tumor necrosis factor (tnf)-, and fas-induced t cell apoptosis in covid-19 patients. |
2020-09-25 |
2023-08-13 |
Not clear |
| Bingbin Wang, Wendong Li. Edaravone Protects against Pancreatic and Intestinal Injury after Acute Pancreatitis via Nuclear Factor-κB Signaling in Mice. Biological & pharmaceutical bulletin. vol 43. issue 3. 2020-09-24. PMID:32115510. |
this was demonstrated by a reduction in histological score, apoptosis, interleukin (il)-6, il-1β and tumor necrosis factor (tnf)-α, along with obstructing activation of toll-like receptor 4 (tlr4) and nuclear factor-κb (nfκb). |
2020-09-24 |
2023-08-13 |
mouse |
| Dario Priem, Michael Devos, Sarah Druwé, Arne Martens, Karolina Slowicka, Adrian T Ting, Manolis Pasparakis, Wim Declercq, Peter Vandenabeele, Geert van Loo, Mathieu J M Bertran. A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell death & disease. vol 10. issue 10. 2020-09-23. PMID:31534131. |
in the present study, we provide in vitro and in vivo evidences that deletion of a20 induces ripk1 kinase-dependent and -independent apoptosis upon single tnf stimulation. |
2020-09-23 |
2023-08-13 |
mouse |
| Nerea Mendez-Barbero, Alma Yuste-Montalvo, Emilio Nuñez-Borque, Bettina M Jensen, Carmen Gutiérrez-Muñoz, Jaime Tome-Amat, María Garrido-Arandia, Araceli Díaz-Perales, Contanza Ballesteros-Martinez, Jose Julio Laguna, J M Beitia, Lars K Poulsen, Javier Cuesta-Herranz, Luis Miguel Blanco-Colio, Vanesa Esteba. The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock. The Journal of allergy and clinical immunology. vol 145. issue 2. 2020-09-22. PMID:31679818. |
the tnf-like weak inducer of apoptosis (tweak) and its sole receptor, fibroblast growth factor-inducible molecule 14 (fn14), belong to the tnf superfamily and are involved in proinflammatory responses. |
2020-09-22 |
2023-08-13 |
Not clear |
| Jaw Long Sun, A M Abd El-Aty, Ji Hoon Jeong, Tae Woo Jun. Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway. The American journal of Chinese medicine. vol 48. issue 4. 2020-09-17. PMID:32431178. |
concentrations of tumor necrosis factor alpha (tnf[formula: see text]) and monocyte chemoattractant protein-1 (mcp-1) in culture media were assessed by enzyme-linked immunosorbent assay (elisa) and apoptosis was evaluated by a cell viability assay and a caspase-3 activity measurement kit. |
2020-09-17 |
2023-08-13 |
Not clear |
| Wenmei Zhang, Yanna Li, Xin Xi, Guangfa Zhu, Shenghao Wang, Yan Liu, Man Son. MicroRNA‑15a‑5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP‑2 signaling pathway. International journal of molecular medicine. vol 45. issue 2. 2020-09-11. PMID:31894295. |
in addition, the overexpression of mir‑15a‑5p reduced pasmc proliferation, induced apoptosis, promoted the activity of caspase‑3/9, induced the protein expression of b‑cell lymphoma 2‑associated x protein (bax), decreased the expression of b‑cell lymphoma 2 (bcl‑2), increased inflammation, as indicated by the expression of tumor necrosis factor‑α (tnf)‑α and interleukin (il)‑1β, il‑6 and il‑18, suppressed the protein expression of vascular endothelial growth factor (vegf), and promoted the protein expression levels of phosphorylated (p)‑p38 mitogen‑activated protein kinase (p38) and matrix metalloproteinase (mmp)‑2 in the pasmcs of rats with mct‑induced pah. |
2020-09-11 |
2023-08-13 |
rat |
| Bin Xiao, Xiao Li, Xiu-Yun Feng, Shuai Gong, Zhi-Bin Li, Jie Zhang, Hong-Jie Yuan, Jing-He Ta. Restraint stress of male mice induces apoptosis in spermatozoa and spermatogenic cells: role of the FasL/Fas system†. Biology of reproduction. vol 101. issue 1. 2020-09-07. PMID:31066896. |
however, incubation with fasl did not affect sperm motility and apoptosis, while incubation with tumor necrosis factor (tnf)-α did. |
2020-09-07 |
2023-08-13 |
mouse |
| Yigao Zhu, Jun Li, Qingwei Li, Yue Pan. Characterization of lamprey (Lampetra japonica) tnfr10-like gene: A potential granulocyte marker molecule and its immune functions. Molecular immunology. vol 124. 2020-09-04. PMID:32497752. |
by binding to tumor necrosis factor (tnf), it can participate in inflammatory response, apoptosis, lymphocyte homeostasis and tissue development. |
2020-09-04 |
2023-08-13 |
Not clear |
| Ezgi Ozyerli-Goknar, Ilknur Sur-Erdem, Fidan Seker, Ahmet Cingöz, Alisan Kayabolen, Zeynep Kahya-Yesil, Fırat Uyulur, Melike Gezen, Nazife Tolay, Batu Erman, Mehmet Gönen, James Dunford, Udo Oppermann, Tugba Bagci-Onde. The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma. Cell death & disease. vol 10. issue 12. 2020-08-31. PMID:31772153. |
trail (tnf related apoptosis inducing ligand) is a potent anti-cancer agent that can induce apoptosis selectively in cancer cells. |
2020-08-31 |
2023-08-13 |
Not clear |
| Xiaolan Zhang, Chun Lin, Junwei Song, Han Chen, Xuhong Chen, Liangliang Ren, Zhongqiu Zhou, Jinyuan Pan, Zhenjun Yang, Wenhao Bao, Xueping Ke, Jianan Yang, Yingying Liang, Hongbiao Huang, Daolin Tang, Lili Jiang, Jinbao Li. Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma. Cell death & disease. vol 10. issue 10. 2020-08-27. PMID:31558697. |
mechanistically, parkin promotes tnf receptor-associated factor (traf) 2 and traf6 degradation and thus facilitates nuclear factor-kappa-b (nf-κb) inhibition, which finally results in apoptosis. |
2020-08-27 |
2023-08-13 |
human |
| Nagat Younan, Samah Elattar, Mira Farouk, Laila Rashed, Suzanne Estapha. Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. Physiological reports. vol 7. issue 17. 2020-08-18. PMID:31496048. |
a significant increase in alt level and area of liver tissue defects with a significant increase in glucose homa ir, serum ffa, il6, il1b, tnf α, liver tgs (triglycerides), inflammation, apoptosis, srebp1c, acc1 were found in ovariectomized rats as compared to control group with a significant decrease in ppar α, lc3, ampk and sirt1. |
2020-08-18 |
2023-08-13 |
rat |
| Nagat Younan, Samah Elattar, Mira Farouk, Laila Rashed, Suzanne Estapha. Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. Physiological reports. vol 7. issue 17. 2020-08-18. PMID:31496048. |
dppi treated rats with and without exercise showed a significant improvement in alt and area of liver tissue defects, inflammation and apoptosis and serum il6, il1b, tnf α, ffa, liver lc3, sirt1, ampk, tgs, ppar α, acc1 and srebp1c as compared to the ovariectomized group. |
2020-08-18 |
2023-08-13 |
rat |
| Hülya Çevik-Aras, Göran Kjeller, Lena Larsso. Expression of tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in minor salivary glands and saliva. Journal of immunological methods. vol 476. 2020-08-17. PMID:31629739. |
expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) in minor salivary glands and saliva. |
2020-08-17 |
2023-08-13 |
Not clear |
| Hülya Çevik-Aras, Göran Kjeller, Lena Larsso. Expression of tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in minor salivary glands and saliva. Journal of immunological methods. vol 476. 2020-08-17. PMID:31629739. |
the aim of this study was to characterize the baseline expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) in minor salivary glands, gingiva and saliva from healthy individuals. |
2020-08-17 |
2023-08-13 |
Not clear |
| Ali Hassanzadeh, Adel Naimi, Majid F Hagh, Raedeh Saraei, Faroogh Marofi, Saeed Solal. Kaempferol Improves TRAIL-Mediated Apoptosis in Leukemia MOLT-4 Cells by the Inhibition of Anti-apoptotic Proteins and Promotion of Death Receptors Expression. Anti-cancer agents in medicinal chemistry. vol 19. issue 15. 2020-08-13. PMID:31364517. |
tumor necrosis factor-related apoptosis-inducing ligand (trail or apo2l) is a member of the tumor necrosis factor (tnf) superfamily, which stimulates apoptosis in a wide range of cancer cells through binding to death receptors 4 and 5 (dr4/5). |
2020-08-13 |
2023-08-13 |
Not clear |
| Mingli Li, Shiyao Sun, Jessica Priest, Xiaolin Bi, Yun Fa. Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression. Cell death & disease. vol 10. issue 8. 2020-07-30. PMID:31409797. |
activation of tnf can lead to distinct cellular outcomes including inflammation, cell survival, and different forms of cell death, such as apoptosis and necrosis in a context-dependent manner. |
2020-07-30 |
2023-08-13 |
drosophila_melanogaster |
| Chandrasekharan Guruvayoorappan, Girija Kutta. β-Carotene down-regulates inducible nitric oxide synthase gene expression and induces apoptosis by suppressing bcl-2 expression and activating caspase-3 and p53 genes in B16F-10 melanoma cells. Nutrition research (New York, N.Y.). vol 27. issue 6. 2020-07-30. PMID:32726891. |
the objective of this research was to assess the effect of β-carotene on the regulation of nitric oxide (no) and tumor necrosis factor (tnf)-α production and stimulation of apoptosis in b16f-10 melanoma cells. |
2020-07-30 |
2023-08-13 |
Not clear |
| Eunbi Jo, Hyun-Jin Jang, Kyeong Eun Yang, Min Su Jang, Yang Hoon Huh, Hwa-Seung Yoo, Jun Soo Park, Ik-Soon Jang, Soo Jung Par. Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation. BMC complementary medicine and therapies. vol 20. issue 1. 2020-07-29. PMID:32020859. |
tumor necrosis factor (tnf) and tnf-α modulates cell survival and apoptosis through nf- κb signaling. |
2020-07-29 |
2023-08-13 |
Not clear |