| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaojie Sun, Manhua Cui, Ding Wang, Baofeng Guo, Ling Zhan. Tumor necrosis factor-related apoptosis inducing ligand overexpression and Taxol treatment suppresses the growth of cervical cancer cells Oncology letters. vol 15. issue 4. 2020-10-01. PMID:29556305. |
tumor necrosis factor-related apoptosis inducing ligand overexpression and taxol treatment suppresses the growth of cervical cancer cells tumor necrosis factor-related apoptosis inducing ligand (trail) is a member of tumor necrosis factor (tnf) superfamily and functions to promote apoptosis by binding to cell surface death receptor (dr)4 and dr5. |
2020-10-01 |
2023-08-13 |
human |
| Anna-Laura Kretz, Silvia von Karstedt, Andreas Hillenbrand, Doris Henne-Bruns, Uwe Knippschild, Anna Trauzold, Johannes Lemk. Should We Keep Walking along the Trail for Pancreatic Cancer Treatment? Revisiting TNF-Related Apoptosis-Inducing Ligand for Anticancer Therapy. Cancers. vol 10. issue 3. 2020-10-01. PMID:29562636. |
many hopes for cancer treatment have been placed in the death ligand tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) since it was reported to induce apoptosis selectively in tumor cells in vitro and in vivo. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yutaka Osug. Current concepts of the pathogenesis of endometriosis. Reproductive medicine and biology. vol 9. issue 1. 2020-10-01. PMID:29699325. |
an increased level of osteoprotegerin in the peritoneal fluid of women with endometriosis is suggested to impede tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail)-induced apoptosis of endometriotic cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Peng Guo, Shun-Wen Zhang, Jie Zhang, Jiang-Tao Dong, Jiang-Dong Wu, Su-Tu Tang, Jun-Ting Yang, Wan-Jiang Zhang, Fang W. Effects of imipenem combined with low-dose cyclophosphamide on the intestinal barrier in septic rats. Experimental and therapeutic medicine. vol 16. issue 3. 2020-10-01. PMID:30186419. |
to investigate the effect of imipenem combined with low-dose ctx on the intestinal barrier, the markers of histopathology, intestinal permeability, intestinal epithelial apoptosis, cytokines interleukin (il)-6, il-10 and tumor necrosis factor (tnf)-α, and tight junction proteins zonula occludens (zo)-1, occludin and claudin-2, were quantitatively and qualitatively evaluated. |
2020-10-01 |
2023-08-13 |
rat |
| Jay R Radke, Iris Figueroa, John M Routes, James L Coo. PIDD-dependent activation of caspase-2-mediated mitochondrial injury in E1A-induced cellular sensitivity to macrophage nitric oxide-induced apoptosis. Cell death discovery. vol 4. 2020-10-01. PMID:30245858. |
expression of the adenovirus e1a oncogene sensitizes tumor cells to innate immune rejection by apoptosis induced by macrophage-produced tumor necrosis factor (tnf)-α and nitric oxide (no). |
2020-10-01 |
2023-08-13 |
Not clear |
| Gunisha Pasricha, Sanjay Mukherjee, Alok K Chakrabart. Apoptotic and Early Innate Immune Responses to PB1-F2 Protein of Influenza A Viruses Belonging to Different Subtypes in Human Lung Epithelial A549 Cells. Advances in virology. vol 2018. 2020-10-01. PMID:30687405. |
results indicated that apoptosis was mediated through death receptor ligands tnf |
2020-10-01 |
2023-08-13 |
human |
| Anna-Laura Kretz, Anna Trauzold, Andreas Hillenbrand, Uwe Knippschild, Doris Henne-Bruns, Silvia von Karstedt, Johannes Lemk. TRAILblazing Strategies for Cancer Treatment. Cancers. vol 11. issue 4. 2020-10-01. PMID:30935038. |
in the late 1990s, tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail), a member of the tnf-family, started receiving much attention for its potential in cancer therapy, due to its capacity to induce apoptosis selectively in tumour cells in vivo. |
2020-10-01 |
2023-08-13 |
Not clear |
| Gelareh Ramezani, Batoul Pourgheysari, Hedayatollah Shirzad, Zahra Souran. Pterostilbene increases Fas expression in T-lymphoblastic leukemia cell lines. Research in pharmaceutical sciences. vol 14. issue 1. 2020-10-01. PMID:30936933. |
fas, as a member of death inducing family of tumor necrosis factor (tnf) receptors with an intracellular death domain, can initiate the extrinsic apoptosis signaling pathway. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kamal Shaik Fakiruddin, Moon Nian Lim, Norshariza Nordin, Rozita Rosli, Zubaidah Zakaria, Syahril Abdulla. Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer. Cancers. vol 11. issue 9. 2020-10-01. PMID:31466290. |
using assays to evaluate cell proliferation, apoptosis, and gene expression, we investigated the efficacy of mscs expressing tumour necrosis factor (tnf)-related apoptosis inducing ligand (msc-trail) to target and destroy cd133+ (prominin-1 positive) nsclc-derived cscs. |
2020-10-01 |
2023-08-13 |
human |
| Daniela Stöhr, Albert Jeltsch, Markus Reh. TRAIL receptor signaling: From the basics of canonical signal transduction toward its entanglement with ER stress and the unfolded protein response. International review of cell and molecular biology. vol 351. 2020-10-01. PMID:32247582. |
the cytokine tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) is a member of the large tnf superfamily that can trigger apoptosis in transformed or infected cells by binding and activating two receptors, trail receptor 1 (trailr1) and trail receptor 2 (trailr2). |
2020-10-01 |
2023-08-13 |
Not clear |
| Bin Yang, Ping Yan, Hui Gong, Lin Zuo, Ying Shi, Jian Guo, Rui Guo, Jun Xie, Bao L. TWEAK protects cardiomyocyte against apoptosis in a PI3K/AKT pathway dependent manner. American journal of translational research. vol 8. issue 9. 2020-09-30. PMID:27725864. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak), a member of tnf superfamily, is a pro-inflammatory and pro-angiogenic cytokine implicated in physiological tissue regeneration and wound repair and is closely related to cardiac remodeling, dysfunction and fibrosis. |
2020-09-30 |
2023-08-13 |
rat |
| Dinesh Babu, Georges Leclercq, Roberto Motterlini, Romain A Lefebvr. Differential Effects of CORM-2 and CORM-401 in Murine Intestinal Epithelial MODE-K Cells under Oxidative Stress. Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28228725. |
the water-soluble corm-a1 reduced apoptosis and nadph oxidase (nox)-derived reactive oxygen species (ros) induced by tumor necrosis factor (tnf)-α/cycloheximide (chx) in mouse mode-k intestinal epithelial cells (iecs), without influencing tnf-α/chx-induced mitochondrial superoxide anion ([formula: see text]). |
2020-09-30 |
2023-08-13 |
mouse |
| Zi-Meng Liu, Xu-Yu Zhang, Juan Chen, Jian-Tong Shen, Zhi-Yi Jiang, Xiang-Dong Gua. Terlipressin protects intestinal epithelial cells against oxygen-glucose deprivation/re-oxygenation injury via the phosphatidylinositol 3-kinase pathway. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28672923. |
following ogd/r, iec-6 cell viability, proliferation and apoptosis, as well as cell cycle dynamics, were assessed and the levels of tumor necrosis factor (tnf)-α and 15-f2t-isoprostane in the culture medium were measured. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ning Bian, Gang Du, Man Fai Ip, Juan Ding, Qing Chang, Zicheng L. Pituitary adenylate cyclase-activating polypeptide attenuates tumor necrosis factor-α-induced apoptosis in endothelial colony-forming cells. Biomedical reports. vol 7. issue 1. 2020-09-30. PMID:28685053. |
tumor necrosis factor (tnf)-α is a significant risk factor for the development of atherosclerosis and a key proinflammatory cytokine known to induce apoptosis in endothelial cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Anton Kichev, Ana A Baburamani, Regina Vontell, Pierre Gressens, Linda Burkly, Claire Thornton, Henrik Hagber. TWEAK Receptor Deficiency Has Opposite Effects on Female and Male Mice Subjected to Neonatal Hypoxia-Ischemia. Frontiers in neurology. vol 9. 2020-09-30. PMID:29706927. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) is a multifunctional cytokine member of the tnf family. |
2020-09-30 |
2023-08-13 |
mouse |
| Hongyan Gong, Weicai Cheng, Yong Wan. Tumor necrosis factor-related apoptosis-inducing ligand inhibits the growth and aggressiveness of colon carcinoma via the exogenous apoptosis signaling pathway. Experimental and therapeutic medicine. vol 17. issue 1. 2020-09-30. PMID:30651763. |
previous studies have demonstrated that tumor necrosis factor-(tnf)-related apoptosis-inducing ligand (trail) reduces the aggressiveness of colon cancer tumors and promotes the apoptosis of colon carcinoma cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ying Chen, Jian-Chang Wang, Chun-Min Yang, Qin Fan, Jun Zheng, Hao Li. Positive acceleration adaptive training attenuates gastric ischemia-reperfusion injury through COX-2 and PGE2 expression. Experimental and therapeutic medicine. vol 17. issue 4. 2020-09-30. PMID:30930978. |
a western blot assay was used to analyze tumor necrosis factor-α (tnf)-α, tumor necrosis factor receptor 1 (tnfr1), tumor necrosis factor-related apoptosis inducing ligand (trail), death receptor (dr) 4, dr5, cyclooxygenase (cox)-2, cox-1 and prostaglandin e2 (pge2) protein expression levels. |
2020-09-30 |
2023-08-13 |
rat |
| Aurélie Rossin, Giorgia Miloro, Anne-Odile Huebe. TRAIL and FasL Functions in Cancer and Autoimmune Diseases: Towards an Increasing Complexity. Cancers. vol 11. issue 5. 2020-09-30. PMID:31072029. |
tumor necrosis factor-related apoptosis inducing ligand (trail/tnfsf10) and fas ligand (fasl/tnfsf6), two major cytokines of the tnf (tumor necrosis factor) superfamily, exert their main functions from the immune system compartment. |
2020-09-30 |
2023-08-13 |
mouse |
| Nani Wang, Hailiang Xin, Pingcui Xu, Zhongming Yu, Dan Sho. Erxian Decoction Attenuates TNF-α Induced Osteoblast Apoptosis by Modulating the Akt/Nrf2/HO-1 Signaling Pathway. Frontiers in pharmacology. vol 10. 2020-09-30. PMID:31551787. |
evaluations of bone mineral density, serum estradiol level, trabecular area fraction, serum calcium levels, and tumor necrosis factor (tnf)-α levels in ovariectomized rats, as well as cell proliferation assays, apoptosis assays, and western blotting in mc3t3-e1 osteoblasts were performed for further experimental validation. |
2020-09-30 |
2023-08-13 |
rat |
| Reena Kumari, Senthilnathan Palaniyandi, Ethan Strattan, Timothy Huang, Katharina Kohler, Nashwan Jabbour, Joanna Dalland, Jing Du, Melissa V Kesler, Youhai H Chen, Gerhard C Hildebrand. TNFAIP8 Deficiency Exacerbates Acute Graft Versus Host Disease in a Murine Model of Allogeneic Hematopoietic Cell Transplantation. Transplantation. vol 104. issue 3. 2020-09-30. PMID:31634333. |
tumor necrosis factor (tnf)-alpha-induced protein 8 (tnfaip8 or tipe) acts as a negative mediator of apoptosis via inhibition of caspase-3 activation, promotes cell proliferation and tipe deficiency is associated with increased inflammation. |
2020-09-30 |
2023-08-13 |
Not clear |