| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristiana Barbati, Tania Colasanti, Marta Vomero, Fulvia Ceccarelli, Alessandra Ida Celia, Carlo Perricone, Francesca Romana Spinelli, Fabrizio Conti, Guido Valesini, Cristiano Alessandr. Up-regulation of autophagy by etanercept treatment results in TNF-induced apoptosis reduction in EA.hy926 endothelial cell line. Clinical and experimental rheumatology. vol 39. issue 3. 2021-05-25. PMID:32896251. |
we investigated the contribution of tnf to endothelial dysfunction and the effect of in vitro treatment with etanercept, with a special focus on autophagy and apoptosis pathways. |
2021-05-25 |
2023-08-13 |
Not clear |
| Érica Leandro Marciano Vieira, Paulo Caramelli, Natalia Pessoa Rocha, Maíra da Glória Freitas Cardoso, Aline Silva de Miranda, Antônio Lúcio Teixeira, Leonardo Cruz de Souz. Tumor necrosis factor superfamily molecules are increased in behavioral variant frontotemporal dementia and correlate with cortical atrophy: An exploratory investigation. Journal of neuroimmunology. vol 354. 2021-05-25. PMID:33711696. |
the aim of this study was to investigate tnf superfamily molecules (tnf, tnf-related weak inducer of apoptosis [tweak], soluble tnf receptor type 1 [stnfri] and soluble tnf receptor type 2 [stnfrii]) in patients with behavioral variant ftd (bvftd) and controls, and to explore potential associations with clinical parameters and brain atrophy. |
2021-05-25 |
2023-08-13 |
human |
| Masahiro Watanabe, Takao Toyomura, Mayuko Tomiyama, Hidenori Wake, Keyue Liu, Kiyoshi Teshigawara, Hideo Takahashi, Masahiro Nishibori, Shuji Mor. Advanced glycation end products (AGEs) synergistically potentiated the proinflammatory action of lipopolysaccharide (LPS) and high mobility group box-1 (HMGB1) through their direct interactions. Molecular biology reports. vol 47. issue 9. 2021-05-18. PMID:32885364. |
previously, we found that advanced glycation endproducts (ages) directly interact with tumor necrosis factor (tnf)-like weak inducer of apoptosis, a cytokine that controls inflammation, and that this interaction inhibited its action. |
2021-05-18 |
2023-08-13 |
Not clear |
| Elisabeth Zechendorf, Caroline E O'Riordan, Lara Stiehler, Natalie Wischmeyer, Fausto Chiazza, Debora Collotta, Bernd Denecke, Sabrina Ernst, Gerhard Müller-Newen, Sina M Coldewey, Bianka Wissuwa, Massimo Collino, Tim-Philipp Simon, Tobias Schuerholz, Christian Stoppe, Gernot Marx, Christoph Thiemermann, Lukas Marti. Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. JCI insight. vol 5. issue 8. 2021-05-17. PMID:32213712. |
treatment with rnase 1 resulted in a significant decrease of apoptosis, induced by the intrinsic pathway, and tnf expression in murine cardiomyocytes exposed to either necrotic cardiomyocytes or serum of septic patients for 16 hours. |
2021-05-17 |
2023-08-13 |
mouse |
| Elisabeth Zechendorf, Caroline E O'Riordan, Lara Stiehler, Natalie Wischmeyer, Fausto Chiazza, Debora Collotta, Bernd Denecke, Sabrina Ernst, Gerhard Müller-Newen, Sina M Coldewey, Bianka Wissuwa, Massimo Collino, Tim-Philipp Simon, Tobias Schuerholz, Christian Stoppe, Gernot Marx, Christoph Thiemermann, Lukas Marti. Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis. JCI insight. vol 5. issue 8. 2021-05-17. PMID:32213712. |
additionally, treatment of septic mice with rnase 1 resulted in a reduction in cardiac apoptosis, tnf expression, and septic cardiomyopathy. |
2021-05-17 |
2023-08-13 |
mouse |
| Shiqi Gao, Yuanjian Fang, Sheng Tu, Huaijun Chen, Anwen Sha. Insight into the divergent role of TRAIL in non-neoplastic neurological diseases. Journal of cellular and molecular medicine. vol 24. issue 19. 2021-05-06. PMID:32827246. |
tumour necrosis factor-related apoptosis-inducing ligand (trail) is a member of the tumour necrosis factor (tnf) superfamily which mainly induces apoptosis of tumour cells and transformed cell lines with no systemic toxicity, whereas they share high sequence homology with tnf and cd95l. |
2021-05-06 |
2023-08-13 |
Not clear |
| Claudio R Bertevello, Bruno R A Russo, Ana C Tahira, Ednilson Hilário Lopes-Junior, Ricardo DeMarco, Katia C Oliveir. The evolution of TNF signaling in platyhelminths suggests the cooptation of TNF receptor in the host-parasite interplay. Parasites & vectors. vol 13. issue 1. 2021-05-06. PMID:32977830. |
the tnf signaling pathway is involved in the regulation of many cellular processes (such as apoptosis and cell proliferation). |
2021-05-06 |
2023-08-13 |
human |
| Narasimha M Beeraka, Venugopal R Bovilla, Shalini H Doreswamy, Sujatha Puttalingaiah, Asha Srinivasan, SubbaRao V Madhunapantul. The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers. Cancers. vol 13. issue 2. 2021-05-02. PMID:33466626. |
glycated stress modulates various signaling pathways that include p38 mitogen-activated protein kinase (p38 mapk), nuclear factor kappa-b (nf-κb), tumor necrosis factor (tnf)-α, etc., which further foster the uncontrolled proliferation, growth, metastasis, angiogenesis, drug resistance, and evasion of apoptosis in several cancers. |
2021-05-02 |
2023-08-13 |
Not clear |
| Xiaofeng Shi, Wei Ma, Yongqi Li, Han Wang, Shuang Pan, Yongquan Pan, Caiming Xu, Lei L. CircPRKCI relieves lipopolysaccharide-induced HK2 cell injury by upregulating the expression of miR-545 target gene ZEB2. BioFactors (Oxford, England). vol 46. issue 3. 2021-04-22. PMID:32104945. |
lps-induced decrease of cell viability, increase of cell apoptosis, as well as elevated productions of tumor necrosis factor (tnf)-α, interleukins (il)-1β, il-6, and il-8 in hk2 cells were attenuated by overexpressed circprkci. |
2021-04-22 |
2023-08-13 |
human |
| Yang Zou, Qiming Liu, Piaoting Guo, Yang Huang, Zhengcong Ye, Jiong H. Anti‑chondrocyte apoptosis effect of genistein in treating inflammation‑induced osteoarthritis. Molecular medicine reports. vol 22. issue 3. 2021-04-20. PMID:32582961. |
moreover, flow cytometry and elisa results demonstrated that genistein could decrease chondrocyte apoptosis and reduce the levels of tumor necrosis factor (tnf)‑α in a dose‑dependent manner. |
2021-04-20 |
2023-08-13 |
rat |
| Jin Wan, Jiao Zhang, Heng Yin, Daiwen Chen, Bing Yu, Jun H. Ameliorative effects of alginate oligosaccharide on tumour necrosis factor-α-induced intestinal epithelial cell injury. International immunopharmacology. vol 89. issue Pt B. 2021-04-20. PMID:33242708. |
in addition, aos pre-treatment increased (p < 0.05) the content of cellular inhibitor of apoptosis protein 2 and decreased (p < 0.05) the expression levels of tnf receptor 1 (tnfr1), tnfr-associated death domain protein and fas-associated death domain protein in tnf-α-treated ipec-j2 cells. |
2021-04-20 |
2023-08-13 |
Not clear |
| Yongjun Wang, Huan Li, Yongsheng Shi, Shuying Wang, Yan Xu, Hanyi Li, Donghai Li. miR-143-3p impacts on pulmonary inflammatory factors and cell apoptosis in mice with mycoplasmal pneumonia by regulating TLR4/MyD88/NF-κB pathway. Bioscience reports. vol 40. issue 7. 2021-04-14. PMID:32597476. |
compared with model group, model mice had up-regulated mir-143-3p expression and decreased myd88 and p-nf-κb p50 protein expressions (all p<0.05); model mice treated with mir-143-3p mimic and tak-242 had reduced interleukin (il)-2 and tumor necrosis factor (tnf)-α contents and protein expressions of myd88, p-nf-κb p50, increased il-10 content, fewer alveolar epithelial cell apoptosis, lower bax expression and higher bcl-2 expression (all p<0.05); however, mice with mir-143-3p inhibitor treatment showed opposite trends in terms of above indicators. |
2021-04-14 |
2023-08-13 |
mouse |
| Madalina Dumitrescu, Violeta Georgeta Trusca, Lorand Savu, Ioana Georgeta Stancu, Attila Cristian Ratiu, Maya Simionescu, Anca Violeta Gafenc. Adenovirus-Mediated International journal of molecular sciences. vol 21. issue 17. 2021-04-13. PMID:32825521. |
adenovirus-mediated fas ligand (first apoptosis signal ligand, fasl, also known as cd95l) is the common executioner of apoptosis within the tumor necrosis factor (tnf) superfamily. |
2021-04-13 |
2023-08-13 |
Not clear |
| Zhenjiang Zhang, Sagar B Patel, Michael R Kin. Micelle-in-Liposomes for Sustained Delivery of Anticancer Agents That Promote Potent TRAIL-Induced Cancer Cell Apoptosis. Molecules (Basel, Switzerland). vol 26. issue 1. 2021-04-13. PMID:33396409. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces cancer cell-specific apoptosis and has garnered intense interest as a promising agent for cancer treatment. |
2021-04-13 |
2023-08-13 |
human |
| Gui-Ming Li, Li-Ping Liu, Bin Yin, Yue-Yue Liu, Wen-Wen Dong, Shuai Gong, Jie Zhang, Jing-He Ta. Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems. Poultry science. vol 99. issue 11. 2021-04-02. PMID:33142528. |
the aim of this study was to test whether hs induces apoptosis of follicular cells and impairs egg production by activating the fasl/fas and tumor necrosis factor (tnf)-α systems. |
2021-04-02 |
2023-08-13 |
Not clear |
| Swati Choksi, Gourav Choudhary, Zheng-Gang Li. Transition from TNF-Induced Inflammation to Death Signaling. Methods in molecular biology (Clifton, N.J.). vol 2248. 2021-04-02. PMID:33185868. |
tumor necrosis factor (tnf) plays a key role in inflammatory responses and in various cellular events such as apoptosis and necroptosis. |
2021-04-02 |
2023-08-13 |
Not clear |
| Yan Li, Shouyan Yang, Honggang Yue, Dandi Yuan, Luxia Li, Jinghong Zhao, Lintao Zha. Unraveling LGALS1 as a Potential Immune Checkpoint and a Predictor of the Response to Anti-PD1 Therapy in Clear Cell Renal Carcinoma. Pathology oncology research : POR. vol 26. issue 3. 2021-04-01. PMID:31428993. |
at last, the genes which correlated with lgals1 expression in ccrcc patients were enriched in tnf alpha signaling pathway which is mainly correlated with t cell apoptosis and survival. |
2021-04-01 |
2023-08-13 |
Not clear |
| Yingying Wang, Sen Guo, Dongmei Li, Yongkang Tang, Lei Li, Ling Su, Xiangguo Li. YIPF2 promotes chemotherapeutic agent-mediated apoptosis via enhancing TNFRSF10B recycling to plasma membrane in non-small cell lung cancer cells. Cell death & disease. vol 11. issue 4. 2021-03-31. PMID:32303681. |
usually, both the expression level and the cell surface level of tnfrsf10b (tnf receptor superfamily member 10b) will increase after treatment with some chemotherapeutic agents, which plays a critical role in the apoptosis induction. |
2021-03-31 |
2023-08-13 |
Not clear |
| Run Zhong, Jie-Qiong Li, Si-Wei Wu, Xiu-Miao He, Jin-Cai Xuan, Han Long, Hong-Quan Li. Transcriptome analysis reveals possible antitumor mechanism of Chlorella exopolysaccharide. Gene. vol 779. 2021-03-31. PMID:33588036. |
the results of gene function enrichment analysis showed that the differentially expressed genes (degs) were significantly enriched in apoptosis and tumor-related biological processes and participated in several cancer and apoptosisrelated signaling pathways, including the mapk signaling pathway, tnf signaling pathway, and the pi3k-akt signaling pathway. |
2021-03-31 |
2023-08-13 |
Not clear |
| Young Woo Eom, Rokeya Akter, Wanlu Li, Suji Lee, Soonjae Hwang, Jiye Kim, Mee-Yon Ch. M1 Macrophages Promote TRAIL Expression in Adipose Tissue-Derived Stem Cells, Which Suppresses Colitis-Associated Colon Cancer by Increasing Apoptosis of CD133 International journal of molecular sciences. vol 21. issue 11. 2021-03-30. PMID:32485960. |
m1 macrophages promote trail expression in adipose tissue-derived stem cells, which suppresses colitis-associated colon cancer by increasing apoptosis of cd133 we have previously reported that adipose tissue-derived stem cells (ascs) cultured at high cell density can induce cancer cell death through the expression of type i interferons and tumor necrosis factor (tnf)-related apoptosis-inducing ligands (trail). |
2021-03-30 |
2023-08-13 |
Not clear |