| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingjing Xie, Bo Li, Bing Yao, Pingchao Zhang, Lixin Wang, Hua Lu, Xuan Son. Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment. Bioscience reports. vol 40. issue 2. 2021-03-15. PMID:31808511. |
during disc degeneration, inflammatory cytokine tumor necrosis factor (tnf)-α is correlated with nucleus pulposus (np) cell apoptosis. |
2021-03-15 |
2023-08-13 |
Not clear |
| Rebecca L Feltham, Maryline Moulin, James E Vince, Peter D Mace, Wendy Wei-Lynn Wong, Holly Anderton, Catherine L Day, David L Vaux, John Silk. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. The Journal of biological chemistry. vol 292. issue 34. 2021-03-14. PMID:28842477. |
tumor necrosis factor (tnf) signaling, but not tweak (tnf-like weak inducer of apoptosis)-triggered ciap1 (cellular inhibitor of apoptosis protein 1) degradation, requires ciap1 ring dimerization and e2 binding. |
2021-03-14 |
2023-08-13 |
Not clear |
| Kehan Li, Cunte Chen, Rili Gao, Xibao Yu, Youxue Huang, Zheng Chen, Zhuandi Liu, Shaohua Chen, Gengxin Luo, Xin Huang, Grzegorz K Przybylski, Yangqiu Li, Chengwu Zen. Inhibition of BCL11B induces downregulation of PTK7 and results in growth retardation and apoptosis in T-cell acute lymphoblastic leukemia. Biomarker research. vol 9. issue 1. 2021-03-10. PMID:33663588. |
similar to the effects of bcl11b silencing, downregulation of ptk7 inhibited cell proliferation and induced apoptosis in molt-4 cells via up-regulating the expression of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and p27. |
2021-03-10 |
2023-08-13 |
Not clear |
| Jianhua Zhang, Miao Chen, Yuyan Zhai, Yu F. HOTAIR regulates lipopolysaccharide-induced inflammatory response in hepatocytes. Journal of cellular physiology. vol 235. issue 5. 2021-03-09. PMID:31621909. |
lps repressed viability, induced apoptosis, and facilitated the expression of interleukin (il)-1β, il-6, and tumor necrosis factor (tnf)-α in l02 and c3a cells. |
2021-03-09 |
2023-08-13 |
human |
| Xiangjun Zhou, Kun Jiang, Haijun Luo, Cheng Wu, Weimin Yu, Fan Chen. Novel lncRNA XLOC_032768 alleviates cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells through TNF-α. International immunopharmacology. vol 83. 2021-03-08. PMID:32278129. |
rna sequencing analysis further confirmed that xloc_032768 could regulate tumor necrosis factor (tnf)-α in the cisplatin-induced apoptosis of hk-2 cells in trans-manner. |
2021-03-08 |
2023-08-13 |
mouse |
| Pratyusha Mandal, A Louise McCormick, Edward S Mocarsk. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis. Viruses. vol 12. issue 11. 2021-03-05. PMID:33126536. |
tnf signaling dictates myeloid and non-myeloid cell crosstalk to execute mcmv-induced extrinsic apoptosis. |
2021-03-05 |
2023-08-13 |
mouse |
| Pratyusha Mandal, A Louise McCormick, Edward S Mocarsk. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis. Viruses. vol 12. issue 11. 2021-03-05. PMID:33126536. |
in this manner, vica has long been known to prevent apoptosis triggered via tumor necrosis factor (tnf) family death receptor-dependent extrinsic signaling. |
2021-03-05 |
2023-08-13 |
mouse |
| Pratyusha Mandal, A Louise McCormick, Edward S Mocarsk. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis. Viruses. vol 12. issue 11. 2021-03-05. PMID:33126536. |
here, we employ fully wild-type murine cytomegalovirus (mcmv) and vica-deficient mcmv (∆m36) to investigate the contribution of tnf signaling to apoptosis during infection of different cell types. |
2021-03-05 |
2023-08-13 |
mouse |
| Pratyusha Mandal, A Louise McCormick, Edward S Mocarsk. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis. Viruses. vol 12. issue 11. 2021-03-05. PMID:33126536. |
human and murine fibroblasts or murine endothelial cells (svec4-10) normally insensitive to tnf become sensitized to ∆m36-induced apoptosis when treated with tnf or tnf-containing bmdm-conditioned medium. |
2021-03-05 |
2023-08-13 |
mouse |
| Pratyusha Mandal, A Louise McCormick, Edward S Mocarsk. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis. Viruses. vol 12. issue 11. 2021-03-05. PMID:33126536. |
we demonstrate that myeloid cells are the natural source of tnf that triggers apoptosis in either myeloid (autocrine) or non-myeloid cells (paracrine) during ∆m36 infection of mice. |
2021-03-05 |
2023-08-13 |
mouse |
| Yung-Che Chen, Chiu Ping Lee, Chang-Chun Hsiao, Po-Yuan Hsu, Ting-Ya Wang, Chao-Chien Wu, Tung-Ying Chao, Sum-Yee Leung, Yu-Ping Chang, Meng-Chih Li. MicroRNA-23a-3p Down-Regulation in Active Pulmonary Tuberculosis Patients with High Bacterial Burden Inhibits Mononuclear Cell Function and Phagocytosis through TLR4/TNF-α/TGF-β1/IL-10 Signaling via Targeting IRF1/SP1. International journal of molecular sciences. vol 21. issue 22. 2021-03-04. PMID:33202583. |
mir-23a-3p mimic transfection reversed esat6-induced reduction of reactive oxygen species generation, and augmented esat6-induced late apoptosis and phagocytosis, in association with down-regulations of the predicted target genes, including tumor necrosis factor (tnf)-α, tlr4, tlr2, il6, il10, notch1, il6r, bcl2, tgf-β1, sp1, and irf1. |
2021-03-04 |
2023-08-13 |
human |
| Maria Feoktistova, Roman Makarov, Martin Leverkus, Amir S Yazdi, Diana Panayotova-Dimitrov. TNF Is Partially Required for Cell-Death-Triggered Skin Inflammation upon Acute Loss of cFLIP. International journal of molecular sciences. vol 21. issue 22. 2021-03-03. PMID:33238518. |
moreover, the lack of tnf in these animals strongly reduced and delayed the epidermal hyperkeratosis and the increased apoptosis in keratinocytes. |
2021-03-03 |
2023-08-13 |
mouse |
| Xingyue Qin, Chen Huang, Ka Wu, Yu Li, Xiao Liang, Min Su, Rong L. Anti-coronavirus disease 2019 (COVID-19) targets and mechanisms of puerarin. Journal of cellular and molecular medicine. vol 25. issue 2. 2021-02-26. PMID:33241658. |
the signalling pathways of puerarin to treat covid-19 included modulation of the pathways of apoptosis, il-17 signalling, mitogen-activated protein kinase (mapk) signalling and tnf signalling. |
2021-02-26 |
2023-08-13 |
Not clear |
| Usman Hyder, Jennifer L McCann, Jinli Wang, Victor Fung, Juan Bayo, Iván D'Ors. The ARF tumor suppressor targets PPM1G/PP2Cγ to counteract NF-κB transcription tuning cell survival and the inflammatory response. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 51. 2021-02-19. PMID:33288725. |
consistently, loss of arf in colon epithelial cells leads to up-regulation of nf-κb antiapoptotic genes upon tnf stimulation and renders cells partially resistant to tnf-induced apoptosis in the presence of agents blocking the antiapoptotic program. |
2021-02-19 |
2023-08-13 |
Not clear |
| Yoshimasa Ando, Yasuhiko Sato, Akihiko Kudo, Takayo Watanabe, Akito Hirakata, Annabelle A Okada, Kazuo Umezawa, Hiroshi Kein. Anti‑inflammatory effects of the NF‑κB inhibitor dehydroxymethylepoxyquinomicin on ARPE‑19 cells. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32377746. |
it was revealed that high concentrations of dhmeq (100 µg/ml) induced apoptosis and necrosis of tumor necrosis factor (tnf)‑α‑stimulated arpe‑19 cells. |
2021-02-16 |
2023-08-13 |
human |
| Srirupa Bhattacharyya, Siddhartha Sankar Ghos. Deciphering insights of novel recombinant tmTNFα in cell growth inhibition. Molecular biology reports. vol 47. issue 5. 2021-02-16. PMID:32385773. |
soluble tnfα, a member of tnf superfamily attributes dual roles in apoptosis and cell proliferation whereas its precursor transmembrane tnfα (tmtnfα) has potential for tumor reduction without initiating proliferation. |
2021-02-16 |
2023-08-13 |
Not clear |
| Atilla Engi. Protein Kinase-Mediated Decision Between the Life and Death. Advances in experimental medicine and biology. vol 1275. 2021-02-15. PMID:33539010. |
while the interaction of tnf with tnf receptor 1 (tnfr1) activates various signal transduction pathways, different death receptors activate three main signal transduction pathways: nuclear factor kappa b (nf-ĸb)-mediated differentiation or pro-inflammatory cytokine synthesis, mitogen-activated protein kinase (mapk)-mediated stress response and caspase-mediated apoptosis. |
2021-02-15 |
2023-08-13 |
human |
| Uddin Md Nazim, Honghua Yin, Sang-Youel Par. Neferine treatment enhances the TRAIL‑induced apoptosis of human prostate cancer cells via autophagic flux and the JNK pathway. International journal of oncology. vol 56. issue 5. 2021-02-08. PMID:32319589. |
tumor necrosis factor‑related apoptosis‑inducing ligand (trail), a member of the tumor necrosis factor (tnf) family, initiates the apoptosis of certain cancer cells. |
2021-02-08 |
2023-08-13 |
human |
| Han-Ze Wang, Ge Gao, Qian-Qian Yang, Xiao-Meng Hou, Bing-Qi Li, Qiang Li, Yin-Chu S. [Study on therapeutic mechanism of Rehmanniae Radix Praeparata- Corni Fructus in sequelae of ischemic stroke based on network pharmacology technology]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 24. 2021-01-27. PMID:33496143. |
kegg pathway analysis showed that rehmanniae radix praeparata-corni fructus could inhibit inflammatory response and apoptosis signaling pathway by regulating hif-vegfa signaling pathway in neural stem cell proliferation, tnf signaling pathway and nf-kappab signaling pathway. |
2021-01-27 |
2023-08-13 |
Not clear |
| Jia Chen, Shuhua Yang, Sheng Huang, Rong Yan, Mingyang Wang, Si Chen, Jing Cai, Miao Long, Peng L. Transcriptome study reveals apoptosis of porcine kidney cells induced by fumonisin B1 via TNF signalling pathway. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 139. 2021-01-25. PMID:32198028. |
transcriptome study reveals apoptosis of porcine kidney cells induced by fumonisin b1 via tnf signalling pathway. |
2021-01-25 |
2023-08-13 |
Not clear |