| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shiqi Gao, Yuanjian Fang, Sheng Tu, Huaijun Chen, Anwen Sha. Insight into the divergent role of TRAIL in non-neoplastic neurological diseases. Journal of cellular and molecular medicine. vol 24. issue 19. 2021-05-06. PMID:32827246. |
tumour necrosis factor-related apoptosis-inducing ligand (trail) is a member of the tumour necrosis factor (tnf) superfamily which mainly induces apoptosis of tumour cells and transformed cell lines with no systemic toxicity, whereas they share high sequence homology with tnf and cd95l. |
2021-05-06 |
2023-08-13 |
Not clear |
| Claudio R Bertevello, Bruno R A Russo, Ana C Tahira, Ednilson Hilário Lopes-Junior, Ricardo DeMarco, Katia C Oliveir. The evolution of TNF signaling in platyhelminths suggests the cooptation of TNF receptor in the host-parasite interplay. Parasites & vectors. vol 13. issue 1. 2021-05-06. PMID:32977830. |
the tnf signaling pathway is involved in the regulation of many cellular processes (such as apoptosis and cell proliferation). |
2021-05-06 |
2023-08-13 |
human |
| Narasimha M Beeraka, Venugopal R Bovilla, Shalini H Doreswamy, Sujatha Puttalingaiah, Asha Srinivasan, SubbaRao V Madhunapantul. The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers. Cancers. vol 13. issue 2. 2021-05-02. PMID:33466626. |
glycated stress modulates various signaling pathways that include p38 mitogen-activated protein kinase (p38 mapk), nuclear factor kappa-b (nf-κb), tumor necrosis factor (tnf)-α, etc., which further foster the uncontrolled proliferation, growth, metastasis, angiogenesis, drug resistance, and evasion of apoptosis in several cancers. |
2021-05-02 |
2023-08-13 |
Not clear |
| Xiaofeng Shi, Wei Ma, Yongqi Li, Han Wang, Shuang Pan, Yongquan Pan, Caiming Xu, Lei L. CircPRKCI relieves lipopolysaccharide-induced HK2 cell injury by upregulating the expression of miR-545 target gene ZEB2. BioFactors (Oxford, England). vol 46. issue 3. 2021-04-22. PMID:32104945. |
lps-induced decrease of cell viability, increase of cell apoptosis, as well as elevated productions of tumor necrosis factor (tnf)-α, interleukins (il)-1β, il-6, and il-8 in hk2 cells were attenuated by overexpressed circprkci. |
2021-04-22 |
2023-08-13 |
human |
| Yang Zou, Qiming Liu, Piaoting Guo, Yang Huang, Zhengcong Ye, Jiong H. Anti‑chondrocyte apoptosis effect of genistein in treating inflammation‑induced osteoarthritis. Molecular medicine reports. vol 22. issue 3. 2021-04-20. PMID:32582961. |
moreover, flow cytometry and elisa results demonstrated that genistein could decrease chondrocyte apoptosis and reduce the levels of tumor necrosis factor (tnf)‑α in a dose‑dependent manner. |
2021-04-20 |
2023-08-13 |
rat |
| Jin Wan, Jiao Zhang, Heng Yin, Daiwen Chen, Bing Yu, Jun H. Ameliorative effects of alginate oligosaccharide on tumour necrosis factor-α-induced intestinal epithelial cell injury. International immunopharmacology. vol 89. issue Pt B. 2021-04-20. PMID:33242708. |
in addition, aos pre-treatment increased (p < 0.05) the content of cellular inhibitor of apoptosis protein 2 and decreased (p < 0.05) the expression levels of tnf receptor 1 (tnfr1), tnfr-associated death domain protein and fas-associated death domain protein in tnf-α-treated ipec-j2 cells. |
2021-04-20 |
2023-08-13 |
Not clear |
| Yongjun Wang, Huan Li, Yongsheng Shi, Shuying Wang, Yan Xu, Hanyi Li, Donghai Li. miR-143-3p impacts on pulmonary inflammatory factors and cell apoptosis in mice with mycoplasmal pneumonia by regulating TLR4/MyD88/NF-κB pathway. Bioscience reports. vol 40. issue 7. 2021-04-14. PMID:32597476. |
compared with model group, model mice had up-regulated mir-143-3p expression and decreased myd88 and p-nf-κb p50 protein expressions (all p<0.05); model mice treated with mir-143-3p mimic and tak-242 had reduced interleukin (il)-2 and tumor necrosis factor (tnf)-α contents and protein expressions of myd88, p-nf-κb p50, increased il-10 content, fewer alveolar epithelial cell apoptosis, lower bax expression and higher bcl-2 expression (all p<0.05); however, mice with mir-143-3p inhibitor treatment showed opposite trends in terms of above indicators. |
2021-04-14 |
2023-08-13 |
mouse |
| Madalina Dumitrescu, Violeta Georgeta Trusca, Lorand Savu, Ioana Georgeta Stancu, Attila Cristian Ratiu, Maya Simionescu, Anca Violeta Gafenc. Adenovirus-Mediated International journal of molecular sciences. vol 21. issue 17. 2021-04-13. PMID:32825521. |
adenovirus-mediated fas ligand (first apoptosis signal ligand, fasl, also known as cd95l) is the common executioner of apoptosis within the tumor necrosis factor (tnf) superfamily. |
2021-04-13 |
2023-08-13 |
Not clear |
| Zhenjiang Zhang, Sagar B Patel, Michael R Kin. Micelle-in-Liposomes for Sustained Delivery of Anticancer Agents That Promote Potent TRAIL-Induced Cancer Cell Apoptosis. Molecules (Basel, Switzerland). vol 26. issue 1. 2021-04-13. PMID:33396409. |
tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces cancer cell-specific apoptosis and has garnered intense interest as a promising agent for cancer treatment. |
2021-04-13 |
2023-08-13 |
human |
| Gui-Ming Li, Li-Ping Liu, Bin Yin, Yue-Yue Liu, Wen-Wen Dong, Shuai Gong, Jie Zhang, Jing-He Ta. Heat stress decreases egg production of laying hens by inducing apoptosis of follicular cells via activating the FasL/Fas and TNF-α systems. Poultry science. vol 99. issue 11. 2021-04-02. PMID:33142528. |
the aim of this study was to test whether hs induces apoptosis of follicular cells and impairs egg production by activating the fasl/fas and tumor necrosis factor (tnf)-α systems. |
2021-04-02 |
2023-08-13 |
Not clear |
| Swati Choksi, Gourav Choudhary, Zheng-Gang Li. Transition from TNF-Induced Inflammation to Death Signaling. Methods in molecular biology (Clifton, N.J.). vol 2248. 2021-04-02. PMID:33185868. |
tumor necrosis factor (tnf) plays a key role in inflammatory responses and in various cellular events such as apoptosis and necroptosis. |
2021-04-02 |
2023-08-13 |
Not clear |
| Yan Li, Shouyan Yang, Honggang Yue, Dandi Yuan, Luxia Li, Jinghong Zhao, Lintao Zha. Unraveling LGALS1 as a Potential Immune Checkpoint and a Predictor of the Response to Anti-PD1 Therapy in Clear Cell Renal Carcinoma. Pathology oncology research : POR. vol 26. issue 3. 2021-04-01. PMID:31428993. |
at last, the genes which correlated with lgals1 expression in ccrcc patients were enriched in tnf alpha signaling pathway which is mainly correlated with t cell apoptosis and survival. |
2021-04-01 |
2023-08-13 |
Not clear |
| Yingying Wang, Sen Guo, Dongmei Li, Yongkang Tang, Lei Li, Ling Su, Xiangguo Li. YIPF2 promotes chemotherapeutic agent-mediated apoptosis via enhancing TNFRSF10B recycling to plasma membrane in non-small cell lung cancer cells. Cell death & disease. vol 11. issue 4. 2021-03-31. PMID:32303681. |
usually, both the expression level and the cell surface level of tnfrsf10b (tnf receptor superfamily member 10b) will increase after treatment with some chemotherapeutic agents, which plays a critical role in the apoptosis induction. |
2021-03-31 |
2023-08-13 |
Not clear |
| Run Zhong, Jie-Qiong Li, Si-Wei Wu, Xiu-Miao He, Jin-Cai Xuan, Han Long, Hong-Quan Li. Transcriptome analysis reveals possible antitumor mechanism of Chlorella exopolysaccharide. Gene. vol 779. 2021-03-31. PMID:33588036. |
the results of gene function enrichment analysis showed that the differentially expressed genes (degs) were significantly enriched in apoptosis and tumor-related biological processes and participated in several cancer and apoptosisrelated signaling pathways, including the mapk signaling pathway, tnf signaling pathway, and the pi3k-akt signaling pathway. |
2021-03-31 |
2023-08-13 |
Not clear |
| Young Woo Eom, Rokeya Akter, Wanlu Li, Suji Lee, Soonjae Hwang, Jiye Kim, Mee-Yon Ch. M1 Macrophages Promote TRAIL Expression in Adipose Tissue-Derived Stem Cells, Which Suppresses Colitis-Associated Colon Cancer by Increasing Apoptosis of CD133 International journal of molecular sciences. vol 21. issue 11. 2021-03-30. PMID:32485960. |
m1 macrophages promote trail expression in adipose tissue-derived stem cells, which suppresses colitis-associated colon cancer by increasing apoptosis of cd133 we have previously reported that adipose tissue-derived stem cells (ascs) cultured at high cell density can induce cancer cell death through the expression of type i interferons and tumor necrosis factor (tnf)-related apoptosis-inducing ligands (trail). |
2021-03-30 |
2023-08-13 |
Not clear |
| Jingjing Xie, Bo Li, Bing Yao, Pingchao Zhang, Lixin Wang, Hua Lu, Xuan Son. Transforming growth factor-β1-regulated Fas/FasL pathway activation suppresses nucleus pulposus cell apoptosis in an inflammatory environment. Bioscience reports. vol 40. issue 2. 2021-03-15. PMID:31808511. |
during disc degeneration, inflammatory cytokine tumor necrosis factor (tnf)-α is correlated with nucleus pulposus (np) cell apoptosis. |
2021-03-15 |
2023-08-13 |
Not clear |
| Rebecca L Feltham, Maryline Moulin, James E Vince, Peter D Mace, Wendy Wei-Lynn Wong, Holly Anderton, Catherine L Day, David L Vaux, John Silk. Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding. The Journal of biological chemistry. vol 292. issue 34. 2021-03-14. PMID:28842477. |
tumor necrosis factor (tnf) signaling, but not tweak (tnf-like weak inducer of apoptosis)-triggered ciap1 (cellular inhibitor of apoptosis protein 1) degradation, requires ciap1 ring dimerization and e2 binding. |
2021-03-14 |
2023-08-13 |
Not clear |
| Kehan Li, Cunte Chen, Rili Gao, Xibao Yu, Youxue Huang, Zheng Chen, Zhuandi Liu, Shaohua Chen, Gengxin Luo, Xin Huang, Grzegorz K Przybylski, Yangqiu Li, Chengwu Zen. Inhibition of BCL11B induces downregulation of PTK7 and results in growth retardation and apoptosis in T-cell acute lymphoblastic leukemia. Biomarker research. vol 9. issue 1. 2021-03-10. PMID:33663588. |
similar to the effects of bcl11b silencing, downregulation of ptk7 inhibited cell proliferation and induced apoptosis in molt-4 cells via up-regulating the expression of tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) and p27. |
2021-03-10 |
2023-08-13 |
Not clear |
| Jianhua Zhang, Miao Chen, Yuyan Zhai, Yu F. HOTAIR regulates lipopolysaccharide-induced inflammatory response in hepatocytes. Journal of cellular physiology. vol 235. issue 5. 2021-03-09. PMID:31621909. |
lps repressed viability, induced apoptosis, and facilitated the expression of interleukin (il)-1β, il-6, and tumor necrosis factor (tnf)-α in l02 and c3a cells. |
2021-03-09 |
2023-08-13 |
human |
| Xiangjun Zhou, Kun Jiang, Haijun Luo, Cheng Wu, Weimin Yu, Fan Chen. Novel lncRNA XLOC_032768 alleviates cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells through TNF-α. International immunopharmacology. vol 83. 2021-03-08. PMID:32278129. |
rna sequencing analysis further confirmed that xloc_032768 could regulate tumor necrosis factor (tnf)-α in the cisplatin-induced apoptosis of hk-2 cells in trans-manner. |
2021-03-08 |
2023-08-13 |
mouse |