| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Pileczki, Laura Pop, Cornelia Braicu, Livia Budisan, Gabriela Bolba Morar, Paloma Del C Monroig-Bosque, Robert V Sandulescu, Ioana Berindan-Neago. Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells. OncoTargets and therapy. vol 9. 2020-09-29. PMID:27956838. |
double gene sirna knockdown of mutant p53 and tnf induces apoptosis in triple-negative breast cancer cells. |
2020-09-29 |
2023-08-13 |
human |
| Valentina Pileczki, Laura Pop, Cornelia Braicu, Livia Budisan, Gabriela Bolba Morar, Paloma Del C Monroig-Bosque, Robert V Sandulescu, Ioana Berindan-Neago. Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells. OncoTargets and therapy. vol 9. 2020-09-29. PMID:27956838. |
simultaneous inhibition of p53 and tnf in hs578t tnbc human cell line revealed a panel of up- and downregulated genes involved in apoptosis. |
2020-09-29 |
2023-08-13 |
human |
| George E Naoum, Donald J Buchsbaum, Fady Tawadros, Ammad Farooqi, Waleed O Arafa. Journey of TRAIL from Bench to Bedside and its Potential Role in Immuno-Oncology. Oncology reviews. vol 11. issue 1. 2020-09-29. PMID:28584572. |
since its identification as a tnf family member, trail (tnf-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. |
2020-09-29 |
2023-08-13 |
Not clear |
| Jun-Juan Lu, Qing Wang, Li Hua Xie, Qiang Zhang, Sheng Hua Su. Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease. Tobacco induced diseases. vol 15. 2020-09-29. PMID:29151827. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak), as a member of the tnf superfamily, has recently been identified as a key regulator of skeletal muscle wasting and metabolic dysfunction. |
2020-09-29 |
2023-08-13 |
rat |
| Yosuke Osawa, Ekumi Kojika, Yukiko Hayashi, Masamichi Kimura, Koji Nishikawa, Sachiyo Yoshio, Hiroyoshi Doi, Tatsuya Kanto, Kiminori Kimur. Tumor necrosis factor-α-mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice. Hepatology communications. vol 2. issue 4. 2020-09-29. PMID:29619419. |
however, it is unclear whether the induction of tumor necrosis factor (tnf)-α-mediated hepatocyte apoptosis in the simple fatty liver triggers liver fibrosis. |
2020-09-29 |
2023-08-13 |
mouse |
| Marine Lambert, Geneviève Pépin, Oscar Peralta-Zaragoza, Raphaël Matusiak, Sophia Ly, Patricia Landry, Patrick Provos. TWEAK Negatively Regulates Human Dicer. Non-coding RNA. vol 2. issue 4. 2020-09-29. PMID:29657270. |
this approach identified tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) as a dicer-interacting protein candidate. |
2020-09-29 |
2023-08-13 |
human |
| Chong Li, Panpan Zhang, Yanming Hao, Dawei He, Yixin Shen, Rongzhu L. Expression and significance of quantum dots in RAW 264.7 macrophages. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30333871. |
the mrna expression levels of genes encoding inflammatory cytokines [tumor necrosis factor (tnf)-α and interleukin (il)-1β] were determined, and cellular assays were performed to investigate the activation, proliferation and apoptosis of raw 264.7 cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rosalind L Ang, Mark Chan, Adrian T Tin. Ripoptocide - A Spark for Inflammation. Frontiers in cell and developmental biology. vol 7. 2020-09-29. PMID:31457011. |
tnf is also a well-known trigger of caspase-dependent apoptosis or caspase-independent necroptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Hua-Wei Zhao, Hao Liu, Li-Ying Liu, Zhi Liu, Xue-Song Don. Analysis of microRNA expression profiling during paraquat-induced injury of murine lung alveolar epithelial cells. The Journal of toxicological sciences. vol 45. issue 8. 2020-09-29. PMID:32741895. |
the bioinformatic analyses suggested that the target genes of these mirnas were involved in mitochondrial apoptosis pathway and dna methylation, and participated in the regulation of pi3k-akt, mtor, ras, tnf, mapk and other signal pathways which related to oxidative stress and apoptosis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Sorah Yoon, Xiwei Wu, Brian Armstrong, Nagy Habib, John J Ross. An RNA Aptamer Targeting the Receptor Tyrosine Kinase PDGFRα Induces Anti-tumor Effects through STAT3 and p53 in Glioblastoma. Molecular therapy. Nucleic acids. vol 14. 2020-09-28. PMID:30594071. |
pdr3 also upregulated serine phosphorylation of p53, which subsequently mediated apoptosis through the death receptors: tumor necrosis factor (tnf)-related apoptosis-inducing ligand receptors 1/2 (trail-r1/r2), fas-associated via death domain (fadd), and fas. |
2020-09-28 |
2023-08-13 |
human |
| Zhaoqian Su, Yinghao W. A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily. Computational and structural biotechnology journal. vol 18. 2020-09-28. PMID:32021664. |
by recognizing members in the tumor necrosis factor (tnf) receptor superfamily, tnf ligand proteins function as extracellular cytokines to activate various signaling pathways involved in inflammation, proliferation, and apoptosis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dirk Geerts, Christina Chopra, Linda Connell. Osteoprotegerin: Relationship to Breast Cancer Risk and Prognosis. Frontiers in oncology. vol 10. 2020-09-28. PMID:32318347. |
in the primary tumor, opg may interact with another tnf superfamily member, tnf-related apoptosis inducing ligand (trail; tnfsf10) to prevent apoptosis induction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Lili Liang, Chuantao Cheng, Guanglei Hu, Xuening Wang, Jing Liu, Zhu Yan, Weihui Zeng, Yumin Xi. TWEAK Promotes the Proliferation of Squamous Cell Carcinoma Cells Through Activating cIAP1 Signals. Frontiers in oncology. vol 10. 2020-09-28. PMID:32351884. |
recent studies showed that tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) induces the proliferation of squamous cell carcinoma (scc) cells. |
2020-09-28 |
2023-08-13 |
human |
| Changhong Ke, Huan Hou, Jiayu Li, Kui Su, Chaohong Huang, Yue Lin, Zhiqiang Lu, Zhiyun Du, Wen Tan, Zhengqiang Yua. Extracellular Vesicle Delivery of TRAIL Eradicates Resistant Tumor Growth in Combination with CDK Inhibition by Dinaciclib. Cancers. vol 12. issue 5. 2020-09-28. PMID:32375399. |
tumour necrosis factor (tnf)-related apoptosis inducing ligand (trail) is a promising anti-cancer agent that rapidly induces apoptosis in cancer cells. |
2020-09-28 |
2023-08-13 |
human |
| Marilena Kampa, George Notas, Efstathios N Stathopoulos, Andreas Tsapis, Elias Castana. The TNFSF Members APRIL and BAFF and Their Receptors TACI, BCMA, and BAFFR in Oncology, With a Special Focus in Breast Cancer. Frontiers in oncology. vol 10. 2020-09-28. PMID:32612943. |
tumor necrosis factor (tnf) superfamily consists of 19 ligands and 29 receptors and is related to multiple cellular events from proliferation and differentiation to apoptosis and tumor reduction. |
2020-09-28 |
2023-08-13 |
Not clear |
| Tian He, Rendong Qu, Caimeng Qin, Zheyi Wang, Yue Zhang, Xiangming Shao, Tao L. Potential mechanisms of Chinese Herbal Medicine that implicated in the treatment of COVID-19 related renal injury. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 28. issue 9. 2020-09-28. PMID:32837217. |
tcm herbs regulate core pathways, such as age-rage, pi3k-akt, tnf and apoptosis pathway, etc. |
2020-09-28 |
2023-08-13 |
Not clear |
| Chao Cheng, Xiao-Bo Liu, Shao-Jie Bi, Qing-Hua Lu, Juan Zhan. Inhibition of Rho-kinase is involved in the therapeutic effects of atorvastatin in heart ischemia/reperfusion. Experimental and therapeutic medicine. vol 20. issue 4. 2020-09-28. PMID:32855683. |
the i/r group was found to have increased myocardial infarct size, cardiomyocyte apoptosis, levels of plasma interleukin (il)-6 and tumor necrosis factor (tnf)-α, superoxide dismutase (sod) activity, malondialdehyde (mda) levels and rho-kinase activity compared with the other treatment groups (p<0.05). |
2020-09-28 |
2023-08-13 |
rat |
| Linnan Zhu, Penghui Yang, Yingze Zhao, Zhenkun Zhuang, Zhifeng Wang, Rui Song, Jie Zhang, Chuanyu Liu, Qianqian Gao, Qumiao Xu, Xiaoyu Wei, Hai-Xi Sun, Beiwei Ye, Yanan Wu, Ning Zhang, Guanglin Lei, Lingxiang Yu, Jin Yan, Guanghao Diao, Fanping Meng, Changqing Bai, Panyong Mao, Yeya Yu, Mingyue Wang, Yue Yuan, Qiuting Deng, Ziyi Li, Yunting Huang, Guohai Hu, Yang Liu, Xiaoqian Wang, Ziqian Xu, Peipei Liu, Yuhai Bi, Yi Shi, Shaogeng Zhang, Zhihai Chen, Jian Wang, Xun Xu, Guizhen Wu, Fu-Sheng Wang, George F Gao, Longqi Liu, William J Li. Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients. Immunity. vol 53. issue 3. 2020-09-25. PMID:32783921. |
we observed increase of plasma cells in both covid-19 and iav patients and xiap associated factor 1 (xaf1)-, tumor necrosis factor (tnf)-, and fas-induced t cell apoptosis in covid-19 patients. |
2020-09-25 |
2023-08-13 |
Not clear |
| Bingbin Wang, Wendong Li. Edaravone Protects against Pancreatic and Intestinal Injury after Acute Pancreatitis via Nuclear Factor-κB Signaling in Mice. Biological & pharmaceutical bulletin. vol 43. issue 3. 2020-09-24. PMID:32115510. |
this was demonstrated by a reduction in histological score, apoptosis, interleukin (il)-6, il-1β and tumor necrosis factor (tnf)-α, along with obstructing activation of toll-like receptor 4 (tlr4) and nuclear factor-κb (nfκb). |
2020-09-24 |
2023-08-13 |
mouse |
| Dario Priem, Michael Devos, Sarah Druwé, Arne Martens, Karolina Slowicka, Adrian T Ting, Manolis Pasparakis, Wim Declercq, Peter Vandenabeele, Geert van Loo, Mathieu J M Bertran. A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell death & disease. vol 10. issue 10. 2020-09-23. PMID:31534131. |
in the present study, we provide in vitro and in vivo evidences that deletion of a20 induces ripk1 kinase-dependent and -independent apoptosis upon single tnf stimulation. |
2020-09-23 |
2023-08-13 |
mouse |