| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nerea Mendez-Barbero, Alma Yuste-Montalvo, Emilio Nuñez-Borque, Bettina M Jensen, Carmen Gutiérrez-Muñoz, Jaime Tome-Amat, María Garrido-Arandia, Araceli Díaz-Perales, Contanza Ballesteros-Martinez, Jose Julio Laguna, J M Beitia, Lars K Poulsen, Javier Cuesta-Herranz, Luis Miguel Blanco-Colio, Vanesa Esteba. The TNF-like weak inducer of the apoptosis/fibroblast growth factor-inducible molecule 14 axis mediates histamine and platelet-activating factor-induced subcutaneous vascular leakage and anaphylactic shock. The Journal of allergy and clinical immunology. vol 145. issue 2. 2020-09-22. PMID:31679818. |
the tnf-like weak inducer of apoptosis (tweak) and its sole receptor, fibroblast growth factor-inducible molecule 14 (fn14), belong to the tnf superfamily and are involved in proinflammatory responses. |
2020-09-22 |
2023-08-13 |
Not clear |
| Jaw Long Sun, A M Abd El-Aty, Ji Hoon Jeong, Tae Woo Jun. Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway. The American journal of Chinese medicine. vol 48. issue 4. 2020-09-17. PMID:32431178. |
concentrations of tumor necrosis factor alpha (tnf[formula: see text]) and monocyte chemoattractant protein-1 (mcp-1) in culture media were assessed by enzyme-linked immunosorbent assay (elisa) and apoptosis was evaluated by a cell viability assay and a caspase-3 activity measurement kit. |
2020-09-17 |
2023-08-13 |
Not clear |
| Wenmei Zhang, Yanna Li, Xin Xi, Guangfa Zhu, Shenghao Wang, Yan Liu, Man Son. MicroRNA‑15a‑5p induces pulmonary artery smooth muscle cell apoptosis in a pulmonary arterial hypertension model via the VEGF/p38/MMP‑2 signaling pathway. International journal of molecular medicine. vol 45. issue 2. 2020-09-11. PMID:31894295. |
in addition, the overexpression of mir‑15a‑5p reduced pasmc proliferation, induced apoptosis, promoted the activity of caspase‑3/9, induced the protein expression of b‑cell lymphoma 2‑associated x protein (bax), decreased the expression of b‑cell lymphoma 2 (bcl‑2), increased inflammation, as indicated by the expression of tumor necrosis factor‑α (tnf)‑α and interleukin (il)‑1β, il‑6 and il‑18, suppressed the protein expression of vascular endothelial growth factor (vegf), and promoted the protein expression levels of phosphorylated (p)‑p38 mitogen‑activated protein kinase (p38) and matrix metalloproteinase (mmp)‑2 in the pasmcs of rats with mct‑induced pah. |
2020-09-11 |
2023-08-13 |
rat |
| Bin Xiao, Xiao Li, Xiu-Yun Feng, Shuai Gong, Zhi-Bin Li, Jie Zhang, Hong-Jie Yuan, Jing-He Ta. Restraint stress of male mice induces apoptosis in spermatozoa and spermatogenic cells: role of the FasL/Fas system†. Biology of reproduction. vol 101. issue 1. 2020-09-07. PMID:31066896. |
however, incubation with fasl did not affect sperm motility and apoptosis, while incubation with tumor necrosis factor (tnf)-α did. |
2020-09-07 |
2023-08-13 |
mouse |
| Yigao Zhu, Jun Li, Qingwei Li, Yue Pan. Characterization of lamprey (Lampetra japonica) tnfr10-like gene: A potential granulocyte marker molecule and its immune functions. Molecular immunology. vol 124. 2020-09-04. PMID:32497752. |
by binding to tumor necrosis factor (tnf), it can participate in inflammatory response, apoptosis, lymphocyte homeostasis and tissue development. |
2020-09-04 |
2023-08-13 |
Not clear |
| Ezgi Ozyerli-Goknar, Ilknur Sur-Erdem, Fidan Seker, Ahmet Cingöz, Alisan Kayabolen, Zeynep Kahya-Yesil, Fırat Uyulur, Melike Gezen, Nazife Tolay, Batu Erman, Mehmet Gönen, James Dunford, Udo Oppermann, Tugba Bagci-Onde. The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma. Cell death & disease. vol 10. issue 12. 2020-08-31. PMID:31772153. |
trail (tnf related apoptosis inducing ligand) is a potent anti-cancer agent that can induce apoptosis selectively in cancer cells. |
2020-08-31 |
2023-08-13 |
Not clear |
| Xiaolan Zhang, Chun Lin, Junwei Song, Han Chen, Xuhong Chen, Liangliang Ren, Zhongqiu Zhou, Jinyuan Pan, Zhenjun Yang, Wenhao Bao, Xueping Ke, Jianan Yang, Yingying Liang, Hongbiao Huang, Daolin Tang, Lili Jiang, Jinbao Li. Parkin facilitates proteasome inhibitor-induced apoptosis via suppression of NF-κB activity in hepatocellular carcinoma. Cell death & disease. vol 10. issue 10. 2020-08-27. PMID:31558697. |
mechanistically, parkin promotes tnf receptor-associated factor (traf) 2 and traf6 degradation and thus facilitates nuclear factor-kappa-b (nf-κb) inhibition, which finally results in apoptosis. |
2020-08-27 |
2023-08-13 |
human |
| Nagat Younan, Samah Elattar, Mira Farouk, Laila Rashed, Suzanne Estapha. Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. Physiological reports. vol 7. issue 17. 2020-08-18. PMID:31496048. |
a significant increase in alt level and area of liver tissue defects with a significant increase in glucose homa ir, serum ffa, il6, il1b, tnf α, liver tgs (triglycerides), inflammation, apoptosis, srebp1c, acc1 were found in ovariectomized rats as compared to control group with a significant decrease in ppar α, lc3, ampk and sirt1. |
2020-08-18 |
2023-08-13 |
rat |
| Nagat Younan, Samah Elattar, Mira Farouk, Laila Rashed, Suzanne Estapha. Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats. Physiological reports. vol 7. issue 17. 2020-08-18. PMID:31496048. |
dppi treated rats with and without exercise showed a significant improvement in alt and area of liver tissue defects, inflammation and apoptosis and serum il6, il1b, tnf α, ffa, liver lc3, sirt1, ampk, tgs, ppar α, acc1 and srebp1c as compared to the ovariectomized group. |
2020-08-18 |
2023-08-13 |
rat |
| Hülya Çevik-Aras, Göran Kjeller, Lena Larsso. Expression of tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in minor salivary glands and saliva. Journal of immunological methods. vol 476. 2020-08-17. PMID:31629739. |
expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) in minor salivary glands and saliva. |
2020-08-17 |
2023-08-13 |
Not clear |
| Hülya Çevik-Aras, Göran Kjeller, Lena Larsso. Expression of tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL) in minor salivary glands and saliva. Journal of immunological methods. vol 476. 2020-08-17. PMID:31629739. |
the aim of this study was to characterize the baseline expression of tumor necrosis factor (tnf)-related apoptosis inducing ligand (trail) in minor salivary glands, gingiva and saliva from healthy individuals. |
2020-08-17 |
2023-08-13 |
Not clear |
| Ali Hassanzadeh, Adel Naimi, Majid F Hagh, Raedeh Saraei, Faroogh Marofi, Saeed Solal. Kaempferol Improves TRAIL-Mediated Apoptosis in Leukemia MOLT-4 Cells by the Inhibition of Anti-apoptotic Proteins and Promotion of Death Receptors Expression. Anti-cancer agents in medicinal chemistry. vol 19. issue 15. 2020-08-13. PMID:31364517. |
tumor necrosis factor-related apoptosis-inducing ligand (trail or apo2l) is a member of the tumor necrosis factor (tnf) superfamily, which stimulates apoptosis in a wide range of cancer cells through binding to death receptors 4 and 5 (dr4/5). |
2020-08-13 |
2023-08-13 |
Not clear |
| Mingli Li, Shiyao Sun, Jessica Priest, Xiaolin Bi, Yun Fa. Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression. Cell death & disease. vol 10. issue 8. 2020-07-30. PMID:31409797. |
activation of tnf can lead to distinct cellular outcomes including inflammation, cell survival, and different forms of cell death, such as apoptosis and necrosis in a context-dependent manner. |
2020-07-30 |
2023-08-13 |
drosophila_melanogaster |
| Chandrasekharan Guruvayoorappan, Girija Kutta. β-Carotene down-regulates inducible nitric oxide synthase gene expression and induces apoptosis by suppressing bcl-2 expression and activating caspase-3 and p53 genes in B16F-10 melanoma cells. Nutrition research (New York, N.Y.). vol 27. issue 6. 2020-07-30. PMID:32726891. |
the objective of this research was to assess the effect of β-carotene on the regulation of nitric oxide (no) and tumor necrosis factor (tnf)-α production and stimulation of apoptosis in b16f-10 melanoma cells. |
2020-07-30 |
2023-08-13 |
Not clear |
| Eunbi Jo, Hyun-Jin Jang, Kyeong Eun Yang, Min Su Jang, Yang Hoon Huh, Hwa-Seung Yoo, Jun Soo Park, Ik-Soon Jang, Soo Jung Par. Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation. BMC complementary medicine and therapies. vol 20. issue 1. 2020-07-29. PMID:32020859. |
tumor necrosis factor (tnf) and tnf-α modulates cell survival and apoptosis through nf- κb signaling. |
2020-07-29 |
2023-08-13 |
Not clear |
| Q Liu, H Wang, X Wang, M Lu, X Tan, L Peng, F Tan, T Xiao, S Xiao, Y Xi. Experimental atopic dermatitis is dependent on the TWEAK/Fn14 signaling pathway. Clinical and experimental immunology. vol 199. issue 1. 2020-07-21. PMID:31515807. |
tumor necrosis factor (tnf)-like weak inducer of apoptosis (tweak) acts through its receptor fibroblast growth factor inducible 14 (fn14), and participates in skin inflammation. |
2020-07-21 |
2023-08-13 |
mouse |
| Yutao Wang, Huan Wen, Jiajun Fu, Lin Cai, Peng-Long Li, Chang-Ling Zhao, Zhu-Feng Dong, Jun-Peng Ma, Xi Wang, Han Tian, Yan Zhang, Ye Liu, Jingjing Cai, Zhi-Gang She, Zan Huang, Wenhua Li, Hongliang L. Hepatocyte TNF Receptor-Associated Factor 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lysine 6-Linked Polyubiquitination of Apoptosis Signal-Regulating Kinase 1. Hepatology (Baltimore, Md.). vol 71. issue 1. 2020-07-14. PMID:31222801. |
hepatocyte tnf receptor-associated factor 6 aggravates hepatic inflammation and fibrosis by promoting lysine 6-linked polyubiquitination of apoptosis signal-regulating kinase 1. |
2020-07-14 |
2023-08-13 |
Not clear |
| Shima Abdollahi, Amin Salehi-Abargouei, Mahtab Tabatabaie, Mohammad Hasan Sheikhha, Hossein Fallahzadeh, Masoud Rahmanian, Omid Toupchian, Elham Karimi-Nazari, Hassan Mozaffari-Khosrav. The effect of resveratrol supplementation on the expression levels of factors associated with cellular senescence and sCD163/sTWEAK ratio in patients with type 2 diabetes mellitus: study protocol for a double-blind controlled randomised clinical trial. BMJ open. vol 9. issue 7. 2020-07-06. PMID:31278094. |
we will also measure serum levels of cluster of differentiation 163 (cd163) and tumour necrosis factor (tnf)-like weak inducer of apoptosis (tweak) as the indicators of cardiovascular status. |
2020-07-06 |
2023-08-13 |
Not clear |
| Fei Wang, Nan-Nan Sun, Lan-Lan Li, Wan-Wan Zhu, Jianbo Xiu, Yan Shen, Qi X. Hepatic progenitor cell activation is induced by the depletion of the gut microbiome in mice. MicrobiologyOpen. vol 8. issue 10. 2020-06-22. PMID:31094067. |
the mrna expression levels of proinflammatory factors (interleukin [il]-1β, il-6, tumor necrosis factor [tnf]-α, and tnf-like weak inducer of apoptosis [tweak]) were also significantly higher in the antibiotic-treated mice than the levels in the control mice. |
2020-06-22 |
2023-08-13 |
mouse |
| Sohei Ito, Yohei Hashimoto, Ryohei Majima, Eichi Nakao, Hiroki Aoki, Michihide Nishihara, Satoko Ohno-Urabe, Aya Furusho, Saki Hirakata, Norifumi Nishida, Makiko Hayashi, Koichiro Kuwahara, Yoshihiro Fukumot. MRTF-A promotes angiotensin II-induced inflammatory response and aortic dissection in mice. PloS one. vol 15. issue 3. 2020-06-18. PMID:32208430. |
angii infusion for 1 day induced pro-inflammatory response, as demonstrated by expressions of il6, tnf, and ccl2, and apoptosis of aortic wall cells, as detected by tunel staining, in an mrtf-a-dependent manner. |
2020-06-18 |
2023-08-13 |
mouse |