| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chunyan Liu, Mengying Zheng, Tian Zhang, Rong Fu, Huaquan Wang, Ting Wang, Weiwei Qi, Zonghong Sha. TRAIL in CD8+ T cells from patients with severe aplastic anemia. International journal of hematology. vol 106. issue 4. 2018-01-05. PMID:28631177. |
tumor necrosis factor-related apoptosis-inducing ligand (trail) is a member of tnf family, which can induce apoptosis and play a significant role in the pathogenesis of many autoimmune disorders. |
2018-01-05 |
2023-08-13 |
Not clear |
| Chengxian Xu, Xiaoxia Wu, Xixi Zhang, Qun Xie, Cunxian Fan, Haibing Zhan. Embryonic Lethality and Host Immunity of RelA-Deficient Mice Are Mediated by Both Apoptosis and Necroptosis. Journal of immunology (Baltimore, Md. : 1950). vol 200. issue 1. 2018-01-05. PMID:29167229. |
in mammalian cells, signaling pathways triggered by tnf can be switched from nf-κb activation to apoptosis and/or necroptosis. |
2018-01-05 |
2023-08-13 |
mouse |
| Keum-Young So, Byung-Hoon Lee, Seon-Hee O. The critical role of autophagy in cadmium-induced immunosuppression regulated by endoplasmic reticulum stress-mediated calpain activation in RAW264.7 mouse monocytes. Toxicology. vol 393. 2017-12-19. PMID:29111403. |
cd decreased cell viability in a dose-dependent manner; cleaved caspase-8, caspase-3, and poly (adp-ribose) polymerase (parp)-1; increased dna laddering; induced ccaat-enhancer-binding protein homologous protein (chop); and reduced tumor necrosis factor (tnf)-α expression; indicating that caspase-dependent and endoplasmic reticulum (er)-mediated apoptosis are involved in cd-induced immunotoxicity. |
2017-12-19 |
2023-08-13 |
mouse |
| M A Aguileta, D Rojas-Rivera, V Goossens, Y Estornes, G Van Isterdael, P Vandenabeele, M J M Bertran. A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress. Cell death and differentiation. vol 23. issue 10. 2017-12-11. PMID:27341185. |
we performed a sirna-based screen to identify new regulators of er stress-induced death and found that repression of the carney complex-associated protein prkar1a specifically protected the cells from er stress-induced apoptosis, and not from apoptosis induced by etoposide or tnf. |
2017-12-11 |
2023-08-13 |
human |
| Herryawan Ryadi Eziwar Dyari, Tristan Rawling, Yongjuan Chen, William Sudarmana, Kirsi Bourget, Julie M Dwyer, Sarah E Allison, Michael Murra. A novel synthetic analogue of ω-3 17,18-epoxyeicosatetraenoic acid activates TNF receptor-1/ASK1/JNK signaling to promote apoptosis in human breast cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 12. 2017-12-11. PMID:28798154. |
a novel synthetic analogue of ω-3 17,18-epoxyeicosatetraenoic acid activates tnf receptor-1/ask1/jnk signaling to promote apoptosis in human breast cancer cells. |
2017-12-11 |
2023-08-13 |
human |
| Herryawan Ryadi Eziwar Dyari, Tristan Rawling, Yongjuan Chen, William Sudarmana, Kirsi Bourget, Julie M Dwyer, Sarah E Allison, Michael Murra. A novel synthetic analogue of ω-3 17,18-epoxyeicosatetraenoic acid activates TNF receptor-1/ASK1/JNK signaling to promote apoptosis in human breast cancer cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 12. 2017-12-11. PMID:28798154. |
silencing of the death receptor tnf receptor 1 (tnfr1), but not fas, dr4, or dr5, and the adapters tradd and tnf receptor-associated factor 2, but not fas-associated death domain, prevented c20e-mediated apoptosis. |
2017-12-11 |
2023-08-13 |
human |
| Luísa M D Magalhães, Agostinho Viana, Augusto C de Jesus, Egler Chiari, Lúcia Galvão, Juliana A Gomes, Kenneth J Gollob, Walderez O Dutr. Distinct Trypanosoma cruzi isolates induce activation and apoptosis of human neutrophils. PloS one. vol 12. issue 11. 2017-12-11. PMID:29176759. |
our further analysis showed that neutrophil death was a result of apoptosis, which was associated with an upregulation of tnf-receptor, tnf and fasligand, but not of fas. |
2017-12-11 |
2023-08-13 |
human |
| Olga V Popik, Evgeny D Petrovskiy, Elena L Mishchenko, Inna N Lavrik, Vladimir A Ivanisenk. Mosaic gene network modelling identified new regulatory mechanisms in HCV infection. Virus research. vol 218. 2017-12-06. PMID:26481968. |
further, we used the developed method to construct a mosaic gene regulatory network including hepatitis c virus (hcv) as the first piece and the tumour necrosis factor (tnf)-induced apoptosis and nf-κb induction pathways as the second piece. |
2017-12-06 |
2023-08-13 |
Not clear |
| Tsutomu Nakazawa, Mitsutoshi Nakamura, Ryosuke Matsuda, Fumihiko Nishimura, Young Soo Park, Yasushi Motoyama, Yasuo Hironaka, Ichiro Nakagawa, Hiroshi Yokota, Shuichi Yamada, Kentaro Tamura, Yasuhiro Takeshima, Kouji Omoto, Yoshitaka Tanaka, Yukiteru Ouji, Masahide Yoshikawa, Takahiro Tsujimura, Hiroyuki Nakas. Antitumor effects of minodronate, a third-generation nitrogen-containing bisphosphonate, in synergy with γδT cells in human glioblastoma in vitro and in vivo. Journal of neuro-oncology. vol 129. issue 2. 2017-12-04. PMID:27393349. |
mda/gdt-mediated apoptosis was blocked by the anti-t cell receptor (tcr) vγ9, mevalonate pathway inhibitor, granzyme b inhibitor, and antitumor necrosis factor (tnf)-α. |
2017-12-04 |
2023-08-13 |
mouse |
| Nieves Peltzer, Maurice Darding, Henning Walcza. Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling. Trends in cell biology. vol 26. issue 6. 2017-11-27. PMID:26877205. |
tnf signaling can result in different biological outcomes including gene activation and cell death induction in the form of apoptosis or necroptosis. |
2017-11-27 |
2023-08-13 |
Not clear |
| Lazaros Vasilikos, Lisanne M Spilgies, Janin Knop, Wendy Wei-Lynn Won. Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins. Immunology and cell biology. vol 95. issue 2. 2017-11-27. PMID:27904150. |
mouse genetics shows that there is some functional redundancy and the use of sms has allowed us to understand how changing the composition of proteins recruited to tnf receptor 1 on tnf ligation can alter protein complex formation and activation of apoptosis or necroptosis, particularly when caspases are inhibited. |
2017-11-27 |
2023-08-13 |
mouse |
| Yupeng Wang, Wenqing Gao, Xuyan Shi, Jingjin Ding, Wang Liu, Huabin He, Kun Wang, Feng Sha. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. Nature. vol 547. issue 7661. 2017-11-20. PMID:28459430. |
here we show that gsdme, which was originally identified as dfna5 (deafness, autosomal dominant 5), can switch caspase-3-mediated apoptosis induced by tnf or chemotherapy drugs to pyroptosis. |
2017-11-20 |
2023-08-13 |
human |
| Katja Piras-Straub, Khaleda Khairzada, Peri Kocabayoglu, Andreas Paul, Guido Gerken, Kerstin Herze. A -1573T>C SNP within the human TRAIL promoter determines TRAIL expression and HCC tumor progression. Cancer medicine. vol 5. issue 10. 2017-11-17. PMID:27580702. |
the cytokine tumor necrosis factor (tnf)-related apoptosis-inducing ligand (trail) induces apoptosis in liver cancer cells but not in normal liver cells. |
2017-11-17 |
2023-08-13 |
human |
| Zhaoqun Liu, Zhi Zhou, Lingling Wang, Wenjing Dong, Limei Qiu, Linsheng Son. The cholinergic immune regulation mediated by a novel muscarinic acetylcholine receptor through TNF pathway in oyster Crassostrea gigas. Developmental and comparative immunology. vol 65. 2017-11-13. PMID:27394930. |
when the oysters received lps stimulation, cgmachr-1 mrna expression in haemocyte was increased to the highest level (6.05-fold, p < 0.05) at 24 h, while blocking cgmachr-1 using receptor antagonists before lps stimulation promoted the expression of oyster tnf, resulting in the increase of haemocyte apoptosis index. |
2017-11-13 |
2023-08-13 |
Not clear |
| Zhaoqun Liu, Zhi Zhou, Lingling Wang, Wenjing Dong, Limei Qiu, Linsheng Son. The cholinergic immune regulation mediated by a novel muscarinic acetylcholine receptor through TNF pathway in oyster Crassostrea gigas. Developmental and comparative immunology. vol 65. 2017-11-13. PMID:27394930. |
these results suggested that cgmachr-1 was the key molecule in cholinergic neuroendocrine-immune system contributing to the regulation of tnf expression and apoptosis process. |
2017-11-13 |
2023-08-13 |
Not clear |
| Renli Qi, Jinxiu Huang, Qi Wang, Hong Liu, Ruisheng Wang, Jing Wang, Feiyun Yan. MicroRNA-224-5p regulates adipocyte apoptosis induced by TNFα via controlling NF-κB activation. Journal of cellular physiology. vol 233. issue 2. 2017-11-13. PMID:28488777. |
tumor necrosis factor (tnf) α can induce cell apoptosis and activate nuclear transcription (nf)-κb in different cell types. |
2017-11-13 |
2023-08-13 |
Not clear |
| Julie Chao, Pengfei Li, Lee Cha. Kallistatin: double-edged role in angiogenesis, apoptosis and oxidative stress. Biological chemistry. vol 398. issue 12. 2017-11-13. PMID:28742513. |
kallistatin attenuates organ injury and apoptosis in animal models, and its heparin-binding site is essential for blocking tumor necrosis factor (tnf)-α-induced apoptosis in endothelial cells. |
2017-11-13 |
2023-08-13 |
mouse |
| Xuening Wang, Shengxiang Xiao, Yumin Xi. Tumor Necrosis Factor Receptor Mediates Fibroblast Growth Factor-Inducible 14 Signaling. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 43. issue 2. 2017-10-31. PMID:28934756. |
tumor necrosis factor (tnf)-related weak inducer of apoptosis (tweak) engages its sole receptor, fibroblast growth factor-inducible 14 (fn14), which participates in various inflammatory and immunologic processes. |
2017-10-31 |
2023-08-13 |
Not clear |
| Sandrine Guis, Philippe Berbis, Delphine Stephan, Daniel Bertin, Florent Amatore, Nathalie Balandraud, Nathalie Lesavre, Sophie Desplat-Jég. TWEAK-binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti-TNF therapy. Journal of translational medicine. vol 14. issue 1. 2017-10-20. PMID:27338143. |
tnf weakly inducer of apoptosis (tweak) is member of the tnf ligand superfamily. |
2017-10-20 |
2023-08-13 |
Not clear |
| Zakareya Gamie, Konstantinos Kapriniotis, Dimitra Papanikolaou, Emma Haagensen, Ricardo Da Conceicao Ribeiro, Kenneth Dalgarno, Anja Krippner-Heidenreich, Craig Gerrand, Eleftherios Tsiridis, Kenneth Samora Ranki. TNF-related apoptosis-inducing ligand (TRAIL) for bone sarcoma treatment: Pre-clinical and clinical data. Cancer letters. vol 409. 2017-10-20. PMID:28888998. |
tnf-related apoptosis-inducing ligand (trail), a member of the tumour necrosis factor (tnf) ligand superfamily (tnflsf), has been found to induce apoptosis in cancer cells while sparing nontransformed cells, and may therefore offer a promising new approach to treatment. |
2017-10-20 |
2023-08-13 |
Not clear |